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NMF-FFB：具有前馈-反馈结构的非负矩阵分解AI 解读

Non-negative matrix factorization (NMF) approximates a non-negative endogenous data matrix as $Y_1 \approx XB$, with non-negative latent components $X$ and coefficients $B$. Standard covariate-aware NMF is feedforward: $B$ depends only on exogenous variables $Y_2$, with no latent feedback among endogenous variables. We propose NMF-FFB (NMF with feedforward-feedback structure), an exploratory data-fitting framework that embeds the simultaneous equation $B = Θ_1 Y_1 + Θ_2 Y_2$…

重新审视并校准用于因果推断的加权生存分析AI 解读

Causal inference with time-to-event outcomes is fundamental in various scientific studies. In a static setup with fitted propensity scores, weighted Kaplan-Meier estimation for survival probabilities and weighted Breslow-Peto estimation for hazard ratios have been widely used, but their statistical properties have been overlooked or studied only to a limited extent. We re-examine the weighted Kaplan-Meier method by formally linking it with the general framework of augmented…

利用异质性实现可识别性：多个有向无环图的贝叶斯排序学习AI 解读

We propose a joint order-based scoring framework for causal structure learning of directed acyclic graph (DAG) models under heterogeneous data settings. We show that leveraging heterogeneity improves the accuracy of causal ordering estimation. In the most favorable case, the causal ordering is identifiable up to two permutations. Building on this framework, we propose an order-based Bayesian method for Gaussian DAG models and establish its theoretical properties in the…

具有干扰、时间序列数据与随机网络的二部因果推断AI 解读

In bipartite causal inference with interference, interventional units might receive treatment or control, and they might affect the outcome of outcome units through their connections on a bipartite network. We study bipartite causal inference with interference based on observational data across time and a changing bipartite network. Under an exposure mapping framework, we define the immediate and carryover causal effects for each outcome unit, representing contrasts of…

时间序列长期方差估计中的尾部后着色AI 解读

Prewhitening is a common approach to deal with strong autocorrelation. In this article, we propose a new approach called tail postcoloring, motivated by it. It uses parametric models to project, or color back, the neglected tail autocovariances in nonparametric estimators onto the final estimator. This approach bridges the non-parametric variance estimator and the parametric coloring model through a scaling factor. It automatically switches between these two arms using a…

利用 TMLE 提高随机对照试验子组分析的效率AI 解读

Subgroup analyses within randomized controlled trials are often underpowered due to limited sample sizes. We address this challenge by leveraging trial participants outside the subgroup of interest to augment estimation within the subgroup. Specifically, we study two Targeted Maximum Likelihood Estimators (TMLEs) that borrow information from non-subgroup participants within the same trial: a TMLE with pooled regression (TMLE-PR) and an Adaptive Targeted Maximum Likelihood…

存在样本流失与补充样本的面板数据闭式估计与推断AI 解读

It has long been established that, if a panel dataset suffers from attrition, auxiliary (refreshment) sampling restores full identification under additional assumptions that still allow for nontrivial attrition mechanisms. Such identification results rely on implausible assumptions about the attrition process or lead to theoretically and computationally challenging estimation procedures. We propose an alternative identifying assumption that, despite its nonparametric nature,…

具有连续效果与实施终点的二型混合整群随机试验设计方法比较AI 解读

Hybrid type 2 studies are gaining popularity for their ability to assess both implementation and health outcomes as co-primary endpoints. Often conducted as cluster-randomized trials (CRTs), five design methods can validly power these studies: p-value adjustment methods, combined outcomes approach, single weighted 1-DF test, disjunctive 2-DF test, and conjunctive test. We compared these methods theoretically and numerically. Theoretical comparisons of power equations allowed…

条件平均处理效应函数下水平集概率的非参数推断AI 解读

The average treatment effect can obscure important heterogeneity when individuals respond differently to a treatment. While the conditional average treatment effect (CATE) function captures such heterogeneity, it is difficult to communicate when it depends on many covariates. Sublevels sets of a multivariate CATE function are equally complicated objects, but the probability of a sublevel set of a CATE function is a single number with a simple interpretation as the proportion…

检测阴性设计的敏感性分析AI 解读

The test-negative design has become popular for evaluating the effectiveness of post-licensure vaccines using observational data. In addition to its logistical convenience on data collection, the design is also believed to control for the differential health-care-seeking behavior between vaccinated and unvaccinated individuals, an important while often unmeasured confounder between the vaccination and infection. Hence, the design has been employed routinely to monitor…

将嵌套随机试验的条件平均处理效应推广至全部符合资格者AI 解读

Randomized controlled trials often enroll participants whose characteristics differ from those of a target population, which can limit the generalizability of the estimated treatment effects when effect modifiers differ across populations. While existing generalizability methods primarily focus on estimating the average treatment effect (ATE) in the target population, such summaries may obscure important heterogeneity that is relevant for clinical and policy decision-making.…

多个时间序列广义误差模型之间的独立性检验AI 解读

We define generalized innovations associated with generalized error models having arbitrary distributions, that is, distributions that can be mixtures of continuous and discrete distributions. These models include stochastic volatility models and regime-switching models. We also propose statistics for testing independence between the generalized errors of these models, extending previous results of Duchesne, Ghoudi and Remillard (2012) obtained for stochastic volatility…

边界断点设计的估计与推断：基于位置的方法AI 解读

Boundary discontinuity designs are used to learn about causal treatment effects along a continuous assignment boundary that splits units into control and treatment groups according to a bivariate location score. We analyze location-based local polynomial treatment effect estimators that directly employ the bivariate score of each unit. We develop pointwise and uniform estimation and inference methods for the \textit{Boundary Average Treatment Effect Curve} (BATEC), as well…

序贯英式拍卖中估值分布的部分识别AI 解读

This paper extends the incomplete model of Haile and Tamer (2003) from static English auctions to sequential English auctions. Because bidders may wait for future opportunities, the static condition that bidders do not let rivals win at beatable prices need not hold. We replace it with a dynamic opportunity-cost restriction, yielding nonparametric valuation bounds without solving a dynamic equilibrium. Sharp bounds are also characterized. We propose a novel moment-condition…

依赖抽样下的最近邻半径AI 解读

Nearest-neighbor methods are fundamental to classical and modern machine learning, yet their geometric properties are typically analyzed under independent sampling. In this paper, we study the nearest-neighbor radii under dependent sampling. We consider strong mixing dependent observations and ask whether dependence changes the scale of nearest-neighbor neighborhoods. We establish distribution-free almost sure convergence under polynomial mixing and sharp non-asymptotic…

临床试验长期结局分位数处理效应的双重／去偏机器学习AI 解读

Long-term outcomes are often unavailable in randomized clinical trials, although short-term surrogate outcomes are commonly observed. External observational data may contain the long-term outcome, but causal comparisons based on such data alone are vulnerable to confounding. Existing surrogate-based data integration methods for long-term outcomes have focused primarily on average treatment effects. We study estimation of quantile treatment effects for long-term outcomes in…

通过高斯过程稳健、自适应地整合平台试验非同期数据AI 解读

A platform trial is an innovative clinical trial design that enables simultaneous and continuous evaluation of multiple treatments within a single master protocol. Existing robust methods restrict analyses to concurrently randomized participants due to concerns that including nonconcurrent data may introduce bias from temporal trends. However, this exclusion represents a missed opportunity to improve efficiency. We propose a Gaussian process framework for incorporating…

稀疏性的脆弱性AI 解读

We show, using three empirical applications, that linear regression estimates predicated on the assumption of sparsity are fragile in two ways. First, we document that different choices of the regressor matrix which do not impact ordinary least squares (OLS) estimates, such as the choice of baseline category with categorical controls, can move sparsity-based estimates by two standard errors or more. Second, we develop two tests of the sparsity assumption by comparing…

通过统计功效进行因果发现AI 解读

Causal discovery methods aim to infer causal direction from observational data. Functional causal discovery approaches use structural asymmetries to identify causal directionality but rely on strong modeling assumptions and provide limited tools for uncertainty quantification. We introduce Causal Discovery via Statistical Power (CDSP), a statistical inference framework that connects causal direction estimation with statistical power and enables uncertainty quantification.…

非受控概率测度族下能否恢复 L¹–L∞ 对偶性？AI 解读

The duality $L^{\infty}\simeq (L^{1})'$ frequently breaks down in the presence of model uncertainty, where a single reference measure $P$ is replaced by a non-dominated family of probability measures $\mathcal{P}$. The unavailability of classical measure-theoretic and functional-analytic tools in this regime poses a significant obstacle to developing robust probabilistic frameworks. We show that this duality can be restored for a broad class of robust statistical models by…

非随机研究中二元结局因果推断方法的选择手册：模拟研究AI 解读

Applied researchers in biomedicine and related fields are often interested in estimating the causal effect of a treatment or intervention. Although randomized clinical trials are considered the gold standard for establishing causal effects, they are not always feasible, and real-world data may represent the only available source of evidence. In such settings, causal effects must be estimated using statistical methods applied to observational data. Over the last few decades,…

拜占庭鲁棒分布式稀疏学习再审视AI 解读

We revisit Byzantine robust distributed estimation for high-dimensional sparse linear models. By combining local $\ell_1$-regularized robust estimation with robust aggregation at the server, the framework applies to pseudo-Huber regression, quantile regression, and sparse SVM. We show that the resulting estimators yield non-asymptotic guarantees and attain near-optimal statistical rates under mild conditions, while remaining communication-efficient. Simulations confirm…

何时能够检测到 p 值操纵？AI 解读

We show that some forms of p-hacking cannot be detected by examining the histogram of t-statistics or their p-values. Even when p-hacking is detectable, standard tests may lack power. We propose a novel test that detects every form of selective reporting that is detectable from the distribution of reported t-statistics. Our test statistic is the distance between the smoothed empirical t-curve and the set of possible honest distributions. This projection test is sharp and can…

无重叠情况下的平均处理效应界AI 解读

The average treatment effect (ATE), the mean difference in potential outcomes under treatment and control, is a canonical causal effect. Overlap, which says that all subjects have non-zero probability of either treatment status, is necessary to identify and estimate the ATE. When overlap fails, the standard solution is to change the estimand, and target a trimmed effect in a subpopulation satisfying overlap. When the outcome is bounded, we demonstrate that this compromise is…