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Sharp Inference on Selected Subgroups in Observational Studies

观察性研究中所选子群的锐利推断

In modern drug development, the broader availability of high-dimensional observational data provides opportunities for scientist to explore subgroup heterogeneity, especially when randomized clinical trials are unavailable due to cost and ethical constraints. However, a common practice that naively searches the subgroup with a high treatment level is often misleading due to the "subgroup selection bias." More importantly, the nature of high-dimensional observational data has…

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Approximate Bayes factors for unit root testing

单位根检验的近似贝叶斯因子

This paper introduces a feasible and practical Bayesian method for unit root testing in financial time series. We propose a convenient approximation of the Bayes factor in terms of the Bayesian Information Criterion as a straightforward and effective strategy for testing the unit root hypothesis. Our approximate approach relies on few assumptions, is of general applicability, and preserves a satisfactory error rate. Among its advantages, it does not require the prior…

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Accounting for recall bias in case-control studies: a causal inference approach

病例对照研究中的回忆偏差:因果推断方法

A case-control study is designed to help determine if an exposure is associated with an outcome. However, since case-control studies are retrospective, they are often subject to recall bias. Recall bias can occur when study subjects do not remember previous events accurately. In this paper, we first define the estimand of interest: the causal odds ratio (COR) for a case-control study. Second, we develop estimation approaches for the COR and present estimates as a function of…

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Estimation and Inference by Stochastic Optimization: Three Examples

通过随机优化进行估计与推断:三个实例

This paper illustrates two algorithms designed in Forneron & Ng (2020): the resampled Newton-Raphson (rNR) and resampled quasi-Newton (rqN) algorithms which speed-up estimation and bootstrap inference for structural models. An empirical application to BLP shows that computation time decreases from nearly 5 hours with the standard bootstrap to just over 1 hour with rNR, and only 15 minutes using rqN. A first Monte-Carlo exercise illustrates the accuracy of the method for…

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Designing Experiments Informed by Observational Studies

利用观察性研究信息设计实验

The increasing availability of passively observed data has yielded a growing methodological interest in "data fusion." These methods involve merging data from observational and experimental sources to draw causal conclusions -- and they typically require a precarious tradeoff between the unknown bias in the observational dataset and the often-large variance in the experimental dataset. We propose an alternative approach to leveraging observational data, which avoids this…

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Spatial Correlation Robust Inference

空间相关稳健推断

We propose a method for constructing confidence intervals that account for many forms of spatial correlation. The interval has the familiar `estimator plus and minus a standard error times a critical value' form, but we propose new methods for constructing the standard error and the critical value. The standard error is constructed using population principal components from a given `worst-case' spatial covariance model. The critical value is chosen to ensure coverage in a…

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Novelty and Primacy: A Long-Term Estimator for Online Experiments

新奇效应与先入效应:在线实验的长期效应估计

Online experiments are the gold standard for evaluating impact on user experience and accelerating innovation in software. However, since experiments are typically limited in duration, observed treatment effects are not always permanently stable, sometimes revealing increasing or decreasing patterns over time. There are multiple causes for a treatment effect to change over time. In this paper, we focus on a particular cause, user-learning, which is primarily associated with…

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Causal Estimation with Functional Confounders

函数型混杂变量下的因果估计

Causal inference relies on two fundamental assumptions: ignorability and positivity. We study causal inference when the true confounder value can be expressed as a function of the observed data; we call this setting estimation with functional confounders (EFC). In this setting, ignorability is satisfied, however positivity is violated, and causal inference is impossible in general. We consider two scenarios where causal effects are estimable. First, we discuss interventions…

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Constructing valid instrumental variables in generalized linear causal models from directed acyclic graphs

从有向无环图构造广义线性因果模型的有效工具变量

Unlike other techniques of causality inference, the use of valid instrumental variables can deal with unobserved sources of both variable errors, variable omissions, and sampling bias, and still arrive at consistent estimates of average treatment effects. The only problem is to find the valid instruments. Using the definition of Pearl (2009) of valid instrumental variables, a formal condition for validity can be stated for variables in generalized linear causal models. The…

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Global jump filters and realized volatility

全局跳跃过滤与已实现波动率

For a semimartingale with jumps, we propose a new estimation method for integrated volatility, i.e., the quadratic variation of the continuous martingale part, based on the global jump filter proposed by Inatsugu and Yoshida [8]. To decide whether each increment of the process has jumps, the global jump filter adopts the upper $α$-quantile of the absolute increments as the threshold. This jump filter is called global since it uses all the observations to classify one…

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Shape-Enforcing Operators for Point and Interval Estimators

点估计与区间估计的形状约束算子

A common problem in econometrics, statistics, and machine learning is to estimate and make inference on functions that satisfy shape restrictions. For example, distribution functions are nondecreasing and range between zero and one, height growth charts are nondecreasing in age, and production functions are nondecreasing and quasi-concave in input quantities. We propose a method to enforce these restrictions ex post on point and interval estimates of the target function by…

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Confidence Intervals for Policy Evaluation in Adaptive Experiments

自适应实验中政策评估的置信区间

Adaptive experiment designs can dramatically improve statistical efficiency in randomized trials, but they also complicate statistical inference. For example, it is now well known that the sample mean is biased in adaptive trials. Inferential challenges are exacerbated when our parameter of interest differs from the parameter the trial was designed to target, such as when we are interested in estimating the value of a sub-optimal treatment after running a trial to determine…

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Linear programming approach to nonparametric inference under shape restrictions: with an application to regression kink designs

形状约束下非参数推断的线性规划方法:回归折点设计应用

We develop a novel method of constructing confidence bands for nonparametric regression functions under shape constraints. This method can be implemented via a linear programming, and it is thus computationally appealing. We illustrate a usage of our proposed method with an application to the regression kink design (RKD). Econometric analyses based on the RKD often suffer from wide confidence intervals due to slow convergence rates of nonparametric derivative estimators. We…

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Identification and Inference Under Narrative Restrictions

叙事约束下的识别与推断

We consider structural vector autoregressions subject to 'narrative restrictions', which are inequality restrictions on functions of the structural shocks in specific periods. These restrictions raise novel problems related to identification and inference, and there is currently no frequentist procedure for conducting inference in these models. We propose a solution that is valid from both Bayesian and frequentist perspectives by: 1) formalizing the identification problem…

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Inference on two component mixtures under tail restrictions

尾部约束下双成分混合模型的推断

Many econometric models can be analyzed as finite mixtures. We focus on two-component mixtures and we show that they are nonparametrically point identified by a combination of an exclusion restriction and tail restrictions. Our identification analysis suggests simple closed-form estimators of the component distributions and mixing proportions, as well as a specification test. We derive their asymptotic properties using results on tail empirical processes and we present a…

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Optimal estimation of functionals of high-dimensional mean and covariance matrix

高维均值与协方差矩阵泛函的最优估计

Motivated by portfolio allocation and linear discriminant analysis, we consider estimating a functional $\mathbfμ^T \mathbfΣ^{-1} \mathbfμ$ involving both the mean vector $\mathbfμ$ and covariance matrix $\mathbfΣ$. We study the minimax estimation of the functional in the high-dimensional setting where $\mathbfΣ^{-1} \mathbfμ$ is sparse. Akin to past works on functional estimation, we show that the optimal rate for estimating the functional undergoes a phase transition…

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Assessing Sensitivity of Machine Learning Predictions.A Novel Toolbox with an Application to Financial Literacy

机器学习预测敏感性评估:金融素养应用的新工具箱

Despite their popularity, machine learning predictions are sensitive to potential unobserved predictors. This paper proposes a general algorithm that assesses how the omission of an unobserved variable with high explanatory power could affect the predictions of the model. Moreover, the algorithm extends the usage of machine learning from pointwise predictions to inference and sensitivity analysis. In the application, we show how the framework can be applied to data with…

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Extreme dependence for multivariate data

多元数据的极端依赖

This article proposes a generalized notion of extreme multivariate dependence between two random vectors which relies on the extremality of the cross-covariance matrix between these two vectors. Using a partial ordering on the cross-covariance matrices, we also generalize the notion of positive upper dependence. We then proposes a means to quantify the strength of the dependence between two given multivariate series and to increase this strength while preserving the marginal…

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Dilation bootstrap

扩张自助法

We propose a methodology for constructing confidence regions with partially identified models of general form. The region is obtained by inverting a test of internal consistency of the econometric structure. We develop a dilation bootstrap methodology to deal with sampling uncertainty without reference to the hypothesized economic structure. It requires bootstrapping the quantile process for univariate data and a novel generalization of the latter to higher dimensions. Once…

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A test of non-identifying restrictions and confidence regions for partially identified parameters

非识别性限制的检验与部分识别参数置信区域

We propose an easily implementable test of the validity of a set of theoretical restrictions on the relationship between economic variables, which do not necessarily identify the data generating process. The restrictions can be derived from any model of interactions, allowing censoring and multiple equilibria. When the restrictions are parameterized, the test can be inverted to yield confidence regions for partially identified parameters, thereby complementing other…

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Few-shot time series segmentation using prototype-defined infinite hidden Markov models

基于原型定义的无限隐马尔可夫模型:小样本时间序列分段

We propose a robust framework for interpretable, few-shot analysis of non-stationary sequential data based on flexible graphical models to express the structured distribution of sequential events, using prototype radial basis function (RBF) neural network emissions. A motivational link is demonstrated between prototypical neural network architectures for few-shot learning and the proposed RBF network infinite hidden Markov model (RBF-iHMM). We show that RBF networks can be…

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Factor-augmented Smoothing Model for Functional Data

函数型数据的因子增强平滑模型

We propose modeling raw functional data as a mixture of a smooth function and a highdimensional factor component. The conventional approach to retrieving the smooth function from the raw data is through various smoothing techniques. However, the smoothing model is not adequate to recover the smooth curve or capture the data variation in some situations. These include cases where there is a large amount of measurement error, the smoothing basis functions are incorrectly…

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The Econometrics and Some Properties of Separable Matching Models

可分离匹配模型的计量方法与若干性质

We present a class of one-to-one matching models with perfectly transferable utility. We discuss identification and inference in these separable models, and we show how their comparative statics are readily analyzed.

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Discretizing Unobserved Heterogeneity

将不可观测异质性离散化

We study discrete panel data methods where unobserved heterogeneity is revealed in a first step, in environments where population heterogeneity is not discrete. We focus on two-step grouped fixed-effects (GFE) estimators, where individuals are first classified into groups using kmeans clustering, and the model is then estimated allowing for group-specific heterogeneity. Our framework relies on two key properties: heterogeneity is a function - possibly nonlinear and…

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