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Operationalizing Complex Causes: A Pragmatic View of Mediation

复杂原因的可操作化:中介分析的务实视角

We examine the problem of causal response estimation for complex objects (e.g., text, images, genomics). In this setting, classical \emph{atomic} interventions are often not available (e.g., changes to characters, pixels, DNA base-pairs). Instead, we only have access to indirect or \emph{crude} interventions (e.g., enrolling in a writing program, modifying a scene, applying a gene therapy). In this work, we formalize this problem and provide an initial solution. Given a…

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Confidence in Causal Discovery with Linear Causal Models

线性因果模型中因果发现的不确定性推断

Structural causal models postulate noisy functional relations among a set of interacting variables. The causal structure underlying each such model is naturally represented by a directed graph whose edges indicate for each variable which other variables it causally depends upon. Under a number of different model assumptions, it has been shown that this causal graph and, thus also, causal effects are identifiable from mere observational data. For these models, practical…

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A tutorial on individualized treatment effect prediction from randomized trials with a binary endpoint

随机试验中二元结局个体化处理效应预测教程

Randomized trials typically estimate average relative treatment effects, but decisions on the benefit of a treatment are possibly better informed by more individualized predictions of the absolute treatment effect. In case of a binary outcome, these predictions of absolute individualized treatment effect require knowledge of the individual's risk without treatment and incorporation of a possibly differential treatment effect (i.e. varying with patient characteristics). In…

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An Interpretable Neural Network for Parameter Inference

用于参数推断的可解释神经网络

Adoption of deep neural networks in fields such as economics or finance has been constrained by the lack of interpretability of model outcomes. This paper proposes a generative neural network architecture - the parameter encoder neural network (PENN) - capable of estimating local posterior distributions for the parameters of a regression model. The parameters fully explain predictions in terms of the inputs and permit visualization, interpretation and inference in the…

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Markov-Switching State-Space Models with Applications to Neuroimaging

马尔可夫切换状态空间模型及其神经影像应用

State-space models (SSM) with Markov switching offer a powerful framework for detecting multiple regimes in time series, analyzing mutual dependence and dynamics within regimes, and asserting transitions between regimes. These models however present considerable computational challenges due to the exponential number of possible regime sequences to account for. In addition, high dimensionality of time series can hinder likelihood-based inference. This paper proposes novel…

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Controlling False Discovery Rates under Cross-Sectional Correlations

横截面相关下的错误发现率控制

We consider controlling the false discovery rate for testing many time series with an unknown cross-sectional correlation structure. Given a large number of hypotheses, false and missing discoveries can plague an analysis. While many procedures have been proposed to control false discovery, most of them either assume independent hypotheses or lack statistical power. A problem of particular interest is in financial asset pricing, where the goal is to determine which…

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Automatically Differentiable Random Coefficient Logistic Demand Estimation

可自动微分的随机系数 Logit 需求估计

We show how the random coefficient logistic demand (BLP) model can be phrased as an automatically differentiable moment function, including the incorporation of numerical safeguards proposed in the literature. This allows gradient-based frequentist and quasi-Bayesian estimation using the Continuously Updating Estimator (CUE). Drawing from the machine learning literature, we outline hitherto under-utilized best practices in both frequentist and Bayesian estimation techniques.…

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General-order observation-driven models: ergodicity and consistency of the maximum likelihood estimator

一般阶数观测驱动模型的遍历性与极大似然估计一致性

The class of observation-driven models (ODMs) includes many models of non-linear time series which, in a fashion similar to, yet different from, hidden Markov models (HMMs), involve hidden variables. Interestingly, in contrast to most HMMs, ODMs enjoy likelihoods that can be computed exactly with computational complexity of the same order as the number of observations, making maximum likelihood estimation the privileged approach for statistical inference for these models. A…

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Searching for consistent associations with a multi-environment knockoff filter

利用多环境 Knockoff 过滤寻找一致关联

This paper develops a method based on model-X knockoffs to find conditional associations that are consistent across diverse environments, controlling the false discovery rate. The motivation for this problem is that large data sets may contain numerous associations that are statistically significant and yet misleading, as they are induced by confounders or sampling imperfections. However, associations consistently replicated under different conditions may be more…

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Modeling Nonstationary Time Series using Locally Stationary Basis Processes

利用局部平稳基过程建模非平稳时间序列

Methods of estimation and forecasting for stationary models are well known in classical time series analysis. However, stationarity is an idealization which, in practice, can at best hold as an approximation, but for many time series may be an unrealistic assumption. We define a class of locally stationary processes which can lead to more accurate uncertainty quantification over making an invalid assumption of stationarity. This class of processes assumes the model…

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A Meta Learning Approach to Discerning Causal Graph Structure

利用元学习辨识因果图结构

We explore the usage of meta-learning to derive the causal direction between variables by optimizing over a measure of distribution simplicity. We incorporate a stochastic graph representation which includes latent variables and allows for more generalizability and graph structure expression. Our model is able to learn causal direction indicators for complex graph structures despite effects of latent confounders. Further, we explore robustness of our method with respect to…

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Multi-Source Causal Inference Using Control Variates

利用控制变量法进行多来源因果推断

While many areas of machine learning have benefited from the increasing availability of large and varied datasets, the benefit to causal inference has been limited given the strong assumptions needed to ensure identifiability of causal effects; these are often not satisfied in real-world datasets. For example, many large observational datasets (e.g., case-control studies in epidemiology, click-through data in recommender systems) suffer from selection bias on the outcome,…

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Feature Extraction for Functional Time Series: Theory and Application to NIR Spectroscopy Data

函数型时间序列的特征提取:理论与近红外光谱应用

We propose a novel method to extract global and local features of functional time series. The global features concerning the dominant modes of variation over the entire function domain, and local features of function variations over particular short intervals within function domain, are both important in functional data analysis. Functional principal component analysis (FPCA), though a key feature extraction tool, only focus on capturing the dominant global features,…

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Retrospective causal inference via matrix completion, with an evaluation of the effect of European integration on cross-border employment

通过矩阵补全进行回溯因果推断:欧洲一体化与跨境就业

We propose a method of retrospective counterfactual imputation in panel data settings with later-treated and always-treated units, but no never-treated units. We use the observed outcomes to impute the counterfactual outcomes of the later-treated using a matrix completion estimator. We propose a novel propensity-score and elapsed-time weighting of the estimator's objective function to correct for differences in the observed covariate and unobserved fixed effects…

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Post-Contextual-Bandit Inference

情境多臂老虎机实验后的统计推断

Contextual bandit algorithms are increasingly replacing non-adaptive A/B tests in e-commerce, healthcare, and policymaking because they can both improve outcomes for study participants and increase the chance of identifying good or even best policies. To support credible inference on novel interventions at the end of the study, nonetheless, we still want to construct valid confidence intervals on average treatment effects, subgroup effects, or value of new policies. The…

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Adaptive Multi-Source Causal Inference

自适应多来源因果推断

Data scarcity is a tremendous challenge in causal effect estimation. In this paper, we propose to exploit additional data sources to facilitate estimating causal effects in the target population. Specifically, we leverage additional source datasets which share similar causal mechanisms with the target observations to help infer causal effects of the target population. We propose three levels of knowledge transfer, through modelling the outcomes, treatments, and confounders.…

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Federated Estimation of Causal Effects from Observational Data

基于联邦观察数据的因果效应估计

Many modern applications collect data that comes in federated spirit, with data kept locally and undisclosed. Till date, most insight into the causal inference requires data to be stored in a central repository. We present a novel framework for causal inference with federated data sources. We assess and integrate local causal effects from different private data sources without centralizing them. Then, the treatment effects on subjects from observational data using a…

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The equivalence of the Delta method and the cluster-robust variance estimator for the analysis of clustered randomized experiments

整群随机实验中 Delta 方法与聚类稳健方差估计的等价性

It often happens that the same problem presents itself to different communities and the solutions proposed or adopted by those communities are different. We take the case of the variance estimation of the population average treatment effect in cluster-randomized experiments. The econometrics literature promotes the cluster-robust variance estimator (Athey and Imbens, 2017), which can be dated back to the study of linear regression with clustered residuals (Liang and Zeger,…

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Asset volatility forecasting:The optimal decay parameter in the EWMA model

资产波动率预测:EWMA 模型的最优衰减参数

The exponentially weighted moving average (EMWA) could be labeled as a competitive volatility estimator, where its main strength relies on computation simplicity, especially in a multi-asset scenario, due to dependency only on the decay parameter, $λ$. But, what is the best election for $λ$ in the EMWA volatility model? Through a large time-series data set of historical returns of the top US large-cap companies; we test empirically the forecasting performance of the EWMA…

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Randomization Inference of Periodicity in Unequally Spaced Time Series with Application to Exoplanet Detection

不等间隔时间序列周期性的随机化推断及系外行星探测应用

The estimation of periodicity is a fundamental task in many scientific areas of study. Existing methods rely on theoretical assumptions that the observation times have equal or i.i.d. spacings, and that common estimators, such as the periodogram peak, are consistent and asymptotically normal. In practice, however, these assumptions are unrealistic as observation times usually exhibit deterministic patterns -- e.g., the nightly observation cycle in astronomy -- that imprint…

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Specification tests for GARCH processes

GARCH 过程的模型设定检验

This paper develops tests for the correct specification of the conditional variance function in GARCH models when the true parameter may lie on the boundary of the parameter space. The test statistics considered are of Kolmogorov-Smirnov and Cramér-von Mises type, and are based on a certain empirical process marked by centered squared residuals. The limiting distributions of the test statistics are not free from (unknown) nuisance parameters, and hence critical values cannot…

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Epidemic change-point detection in general causal time series

一般因果时间序列中的暂时性变点检测

We consider an epidemic change-point detection in a large class of causal time series models, including among other processes, AR($\infty$), ARCH($\infty$), TARCH($\infty$), ARMA-GARCH. A test statistic based on the Gaussian quasi-maximum likelihood estimator of the parameter is proposed. It is shown that, under the null hypothesis of no change, the test statistic converges to a distribution obtained from a difference of two Brownian bridge and diverges to infinity under the…

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Student-t Stochastic Volatility Model With Composite Likelihood EM-Algorithm

Student-t 随机波动率模型与复合似然 EM 算法

A new robust stochastic volatility (SV) model having Student-t marginals is proposed. Our process is defined through a linear normal regression model driven by a latent gamma process that controls temporal dependence. This gamma process is strategically chosen to enable us to find an explicit expression for the pairwise joint density function of the Student-t response process. With this at hand, we propose a composite likelihood (CL) based inference for our model, which can…

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Covariate adjustment in subgroup analyses of randomized clinical trials: A propensity score approach

随机临床试验亚组分析中的协变量调整:倾向得分方法

Background: Subgroup analyses are frequently conducted in randomized clinical trials to assess evidence of heterogeneous treatment effect across patient subpopulations. Although randomization balances covariates within subgroups in expectation, chance imbalance may be amplified in small subgroups and harm the precision. Covariate adjustment in overall analysis of RCT is often conducted, via either ANCOVA or propensity score weighting, but for subgroup analysis has been…

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