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Minimax Optimal Estimator and Improved Error Rate for the MLE in Logistic Regression with Gaussian Design

高斯设计 Logistic 回归的极小极大最优估计与 MLE 误差界改进

We study finite-sample parameter estimation in logistic regression with Gaussian design, where the goal is to estimate $\mathbfθ^*\in \mathbb{R}^d$ with $R=\|\mathbfθ^*\|_2\ge 1$ from i.i.d. samples $\{(\mathbf{x}_i,y_i)\}_{i=1}^n,$ $\mathbf{x}_i \sim N(0,\mathbf{I}_d)$, $y_i\mid \mathbf{x}_i \sim \mathrm{Bernoulli}((1+\exp(-\mathbf{x}_i^\top \mathbfθ^*))^{-1})$. In this paper, we provide the first minimax optimal estimator, and improve on the best known finite-sample error…

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Sensitivity of weighted least squares estimators to omitted variables

加权最小二乘估计量对遗漏变量的敏感性

We introduce tools for assessing the sensitivity, to unobserved confounding, of a common estimator of causal effects that employs weights: the weighted linear regression of the outcome on the treatment and observed covariates. This estimator's bias is a function of two intuitive weighted partial $R^2$ values: (i) the proportion of weighted variance in the treatment that unobserved confounding explains given the covariates and (ii) the proportion of weighted variance in the…

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Testing Conditional Stochastic Dominance at Target Points

目标点处的条件随机占优检验

This paper introduces a test for conditional stochastic dominance between two distributions at prespecified values of a conditioning covariate, referred to as target points. The test uses a one-sided Kolmogorov--Smirnov statistic computed from induced order statistics, the outcomes attached to the conditioning observations closest to the target point, and compares it to a critical value that, given the number of neighbors, requires no resampling, kernel smoothing, or…

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Pattern-Based Sequential Multiple Imputation for Missing Data in Clinical Trials: An Extension for Baseline-Only Early Dropout Subjects

临床试验序贯多重插补:仅有基线数据的早期退出者扩展

Under the ICH E9 (R1) addendum, treatment policy strategies for intercurrent events target the treatment effect regardless of treatment discontinuation. Sequential multiple imputation (MI) models that condition each visit's imputation on discontinuation status or pattern reduce bias relative to mixed models and standard MI, but require every subject to contribute at least one post-baseline observation, an assumption violated by subjects who withdraw before any post-baseline…

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Learning the Macroeconomic Language

学习宏观经济语言

We show how state-of-the-art large language models (LLMs) can be trained effectively on limited historical data for macroeconomic forecasting. We estimate a dynamic stochastic general equilibrium (DSGE) model with stochastic volatility and Student-t shocks on an initial segment of the data to obtain a posterior distribution over structural parameters. We sample from this posterior to generate millions of theory-consistent synthetic panels that, when mixed with macroeconomic…

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Quantile restrictions, revealed rankings, and the limits of multinomial choice

分位数限制、揭示排序与多项选择的边界

This paper analyzes when choice probabilities reveal rankings of deterministic utility indices in semiparametric discrete choice models. It begins with binary choice, where quantile thresholds guarantee ranking recovery, and shows that such thresholds can arise either from behavioral departures from utility maximization (e.g., limited attention) under exchangeable unobservables, or from non-exchangeable unobservables under standard utility maximization. These behavioral and…

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Recursive Multiple Change Point Detection of Nonstationary Time Series: Instability Tests, Estimation and Confidence Intervals

非平稳时间序列的递归多变点检测、估计与置信区间

We develop bootstrap-assisted robust binary segmentation (BARBS), a recursive binary segmentation method for multiple change point detection under general nonstationary temporal dynamics. A novel Gaussian multiplier bootstrap for the CUSUM statistics is proposed, offering robustness to complex dependence structures. Through meticulous calibration of the critical values at each stage of the recursion, BARBS ensures control of the Type I error under the null hypothesis of no…

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From Estimands to Robust Inference of Treatment Effects in Master Protocol Trials

主方案试验:从目标量定义到治疗效应的稳健推断

Master protocol trials use a single overarching protocol to evaluate multiple interventions, diseases, or disease subtypes, where individuals are often randomized to different subsets of intervention arms based on individual characteristics, enrollment timing, and intervention availability. While offering increased flexibility, this constrained and non-uniform intervention assignment poses two fundamental inferential challenges: the precise definition of treatment effects…

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A Neyman-Orthogonalization Approach to the Incidental Parameter Problem in Likelihood Models

似然模型偶然参数问题的 Neyman 正交化方法

A popular approach to perform inference on a target parameter in the presence of nuisance parameters is to construct estimating equations that are orthogonal to the nuisance parameters, in the sense that their expected first derivative is zero. Such first-order orthogonalization allows the estimator of the nuisance parameters to converge at a slower-than-parametric rate. It may, however, not suffice when the nuisance parameters are very imprecisely estimated. Leading…

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Randomization inference for treatment effects on survival outcomes

生存结局治疗效应的随机化推断

The log-rank test and Kaplan--Meier plot are standard tools for analyzing time-to-event data in randomized clinical trials, yet neither provides a summary of the magnitude of the treatment effect. Practitioners typically fill this gap by reporting a hazard ratio from a Cox proportional-hazards model or an acceleration factor from an accelerated failure time (AFT) model, but both require assumptions beyond those needed for the log-rank test or Kaplan--Meier estimator. We…

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Estimation and Inference for Peer Effects under Conditional Random Assignment

条件随机分组下同伴效应的估计与推断

Empirical studies of peer effects often exploit conditional random assignment to peer groups within urns. We develop a GMM framework for estimation and inference in this setting. The framework separately identifies endogenous and contextual peer effects and nests tests of random peer-group assignment as a special case. It permits unknown heteroskedasticity and corrects finite-urn bias in variance estimation. Its asymptotic theory allows the number of peer groups to grow…

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High-Dimensional Assisted Learning for Vertically Distributed Data with Blockwise Missingness

块状缺失的纵向特征分布数据:高维辅助学习

In multi-institutional studies, different parties hold distinct feature blocks for partially overlapping sets of individuals. Responses may also be missing for some records. In such settings, we propose Assisted Learning with Block-Missing Data (ALB) for sparse high-dimensional linear estimation and coordinatewise inference without pooling records or relying on a coordinating server. ALB minimizes a regularized available-case quadratic loss using cyclic block updates. Each…

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Estimating and Testing Kinks in Panel Data Models

面板数据模型中折点的估计与检验

Many economic and financial relationships may change gradually rather than abruptly. We study panel data models in which the coefficient vector is continuous and piecewise linear in calendar time, with a finite number of unknown kink dates at which its slope changes. We propose a penalised least squares estimator that applies adaptive weighted group penalties to the second differences of the coefficient path, and develop asymptotic theory showing that it recovers both the…

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Neural networks for nonlinear regression with serially correlated disturbances: Evidence from cloud cover

带序列相关扰动的非线性回归神经网络:来自云量的证据

We propose a new treatment of nonlinear regression with serially correlated disturbances that incorporates autoregressive moving average structures into feedforward neural networks. The resulting model provides an alternative to modeling temporal dependence using lagged variables. In simulations, the proposed method accurately recovers regression functions of varying complexity and the underlying error dynamics across a range of time-series lengths and signal-to-noise…

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Gaussianization-Based Parameter Estimation for Gamma-Gamma and Lognormal-Rician Turbulence Channels

Gamma–Gamma与对数正态–Rician湍流信道的高斯化参数估计

Accurate parameter estimation for atmospheric turbulence channels is challenging because the probability density functions of the Gamma-Gamma (GG) and Lognormal-Rician (LR) models involve special functions and numerical integrations. This paper proposes two Gaussianization parameter estimators for GG and LR turbulence channels, i.e., the quantile-transformation (QT) estimator and the Box-Cox estimator. The QT estimator employs bidirectional cross-transformation together with…

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A compensatory model for quantile estimation and application to VaR

分位数估计的补偿模型及其在 VaR 中的应用

Unlike the standard two-step workflow of estimating a time series distribution and extracting quantiles from it, this paper proposes a compensatory model to refine quantile estimates based on an existing fitted distribution. We embed a new penalty term in the model and theoretically characterize its ability to bound realized coverage errors, yielding an adaptive quantile estimator. Backtests on the S&P 500 and NASDAQ Composite show that the compensatory model substantially…

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Doubly robust estimation of while-alive estimands in individually-randomized and cluster-randomized trials

个体与整群随机试验中存活期间目标量的双重稳健估计

Randomized trials in chronic disease settings often measure treatment benefit through recurrent non-fatal events that are truncated by death, where conventional summaries either discard recurrences, conflate the treatment effect with survival, or treat death as censoring and forfeit a causal interpretation. While-alive estimands measure event burden per unit time alive, but doubly robust estimation for the exposure-weighted while-alive rate remains undeveloped, particularly…

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Leveraging Generative Artificial Intelligence for Causal Inference with Unstructured Data

利用生成式人工智能对非结构化数据开展因果推断

We introduce GenAI-Powered Inference (GPI), a statistical framework for both causal and predictive inference using unstructured data, including text and images. GPI leverages open-source Generative Artificial Intelligence (GenAI) models---such as large language models and diffusion models---not only to generate unstructured data at scale but also to extract low-dimensional representations that are guaranteed to capture their underlying structure. Applying machine learning to…

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Synthetic Control with Weight Uncertainty: Robust Identification and Statistical Inference

权重不确定性下的合成控制:稳健识别与统计推断

The synthetic control method estimates causal effects by comparing a treated unit with weighted controls matched on its pre-treatment trajectory. However, validity can be compromised when highly correlated controls leave the synthetic weights weakly determined or when treated-control relationships shift after treatment. We propose a new estimand, the weight-robust treatment effect, defined as the optimizer of a worst-case optimization problem over an uncertainty class of…

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Multiscale Dynamic Dependence Estimation over Networks

网络上的多尺度动态依赖估计

In many settings, observed multivariate time series are often nonstationary in nature, i.e., their second order properties vary over time. An additional feature is that their cross-channel dependencies are structured by an underlying network. Together, they give rise to complex interactions between temporal dynamics and network topology. We propose Locally Stationary Wavelet processes on Networks (Net-LSW), a new framework for modelling multiscale, time-varying dependencies…

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Rectified Linear Unit Regression

修正线性单元回归

This paper develops a regression framework for analyzing integrated conditional distribution and quantile functions. The proposed method, termed rectified linear unit (ReLU) regression, projects the ReLU-transformed outcome onto covariates and admits a closed-form estimator. Its population regression function is the best linear approximation to the integrated conditional distribution function of the outcome, and the corresponding convex conjugate, obtained via the…

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On the Graphical Rules for Recovering the Average Treatment Effect Under Selection Bias

选择偏差下恢复平均处理效应的图形规则

Selection bias is a major obstacle toward valid causal inference in epidemiology. Over the past decade, several graphical rules based on causal diagrams have been proposed as sufficient identification conditions for addressing selection bias and recovering causal effects. However, these simple graphical rules are typically coupled with specific identification strategies and estimators. In this article, we show two important cases of selection bias that fall outside the scope…

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Bootstrap Error Estimation and Sketch-Size Selection for Sketched Ridge Regression

压缩岭回归的自助法误差估计与压缩规模选择

Randomized sketching reduces the computational cost of large ridge-regression problems, but the coefficient error depends on the realized sketch. We extend the paired-row bootstrap from randomized least squares to ridge regression, enabling coefficient-error estimation using only compressed data. Under a fixed coefficient dimension and increasing data and sketch sizes, we derive asymptotic linear representations and Gaussian limits for the sketched estimator and the…

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Toward Efficient Estimation of Regional Treatment Effects in Multi-Regional Clinical Trials

多区域临床试验中区域处理效应的有效估计

A multi-regional clinical trial (MRCT) is a single clinical trial conducted in multiple regions simultaneously under a common protocol, which may be used to support parallel submissions to multiple regulatory authorities. For a regional regulatory authority, treatment effects defined specifically for its own region are more relevant to consider than overall treatment effects based on all regions included in an MRCT. A regional treatment effect can be estimated consistently…

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