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将目标估计量与目标试验框架用于观察数据外部对照：实体瘤案例AI 解读

In causal inference, the correct formulation of the scientific question of interest is a crucial step. Here we apply the estimand framework to a comparison of the outcomes of patient-level clinical trials and observational data to help structure the clinical question. In addition, we complement the estimand framework with the target trial framework to address specific issues in defining the estimand attributes using observational data and discuss synergies and differences of…

具有双向不可观测异质性的线性面板回归AI 解读

We study linear panel regression models in which the unobserved error term is an unknown smooth function of two-way unobserved fixed effects. In standard additive or interactive fixed effect models the individual specific and time specific effects are assumed to enter with a known functional form (additive or multiplicative). In this paper, we allow for this functional form to be more general and unknown. We discuss two different estimation approaches that allow consistent…

贝叶斯孟德尔随机化的区间因果零假设检验：三元决策与损失函数校准AI 解读

Our approach to Mendelian Randomization (MR) analysis is designed to increase reproducibility of causal effect "discoveries" by: (i) using a Bayesian approach to inference; (ii) replacing the point null hypothesis with a region of practical equivalence consisting of values of negligible magnitude for the effect of interest, while exploiting the ability of Bayesian analysis to quantify the evidence of the effect falling inside/outside the region; (iii) rejecting the usual…

无需单调性的弱可分模型内生性处理AI 解读

We identify and estimate treatment effects when potential outcomes are weakly separable with a binary endogenous treatment. Vytlacil and Yildiz (2007) proposed an identification strategy that exploits the mean of observed outcomes, but their approach requires a monotonicity condition. In comparison, we exploit full information in the entire outcome distribution, instead of just its mean. As a result, our method does not require monotonicity and is also applicable to general…

近端识别假设违反时的偏差公式AI 解读

Causal inference from observational data often rests on the unverifiable assumption of no unmeasured confounding. Recently, Tchetgen Tchetgen and colleagues have introduced proximal inference to leverage negative control outcomes and exposures as proxies to adjust for bias from unmeasured confounding. However, some of the key assumptions that proximal inference relies on are themselves empirically untestable. Additionally, the impact of violations of proximal inference…

结构工程中的因果性、因果发现与因果推断AI 解读

Much of our experiments are designed to uncover the cause(s) and effect(s) behind a data generating mechanism (i.e., phenomenon) we happen to be interested in. Uncovering such relationships allows us to identify the true working of a phenomenon and, most importantly, articulate a model that may enable us to further explore the phenomenon on hand and/or allow us to predict it accurately. Fundamentally, such models are likely to be derived via a causal approach (as opposed to…

粒子滤波的蒙特卡洛扭曲方法AI 解读

We consider the problem of designing efficient particle filters for twisted Feynman--Kac models. Particle filters using twisted models can deliver low error approximations of statistical quantities and such twisting functions can be learnt iteratively. Practical implementations of these algorithms are complicated by the need to (i) sample from the twisted transition dynamics, and (ii) calculate the twisted potential functions. We expand the class of applicable models using…

先验强化信息准则AI 解读

The widely applicable information criterion (WAIC) has been used as a model selection criterion for Bayesian statistics in recent years. It is an asymptotically unbiased estimator of the Kullback-Leibler divergence between a Bayesian predictive distribution and the true distribution. Not only is the WAIC theoretically more sound than other information criteria, its usefulness in practice has also been reported. On the other hand, the WAIC is intended for settings in which…

基于 Wasserstein 距离的分布稳健政策学习AI 解读

The effects of treatments are often heterogeneous, depending on the observable characteristics, and it is necessary to exploit such heterogeneity to devise individualized treatment rules (ITRs). Existing estimation methods of such ITRs assume that the available experimental or observational data are derived from the target population in which the estimated policy is implemented. However, this assumption often fails in practice because of limited useful data. In this case,…

随机时间序列中的频率调制检测AI 解读

We propose a new statistical test to identify non-stationary frequency-modulated stochastic processes from time series data. Our method uses the instantaneous phase as a discriminatory statistics with reliable critical values derived from surrogate data. We simulated an oscillatory second-order autoregressive process to evaluate the size and power of the test. We found that the test we propose is able to correctly identify more than 99% of non-stationary data when the…

处理状态误分类下的双重差分AI 解读

This paper studies identification and estimation of the average treatment effect on the treated (ATT) in difference-in-difference (DID) designs when the variable that classifies individuals into treatment and control groups (treatment status, D) is endogenously misclassified. We show that misclassification in D hampers consistent estimation of ATT because 1) it restricts us from identifying the truly treated from those misclassified as being treated and 2) differential…

贝叶斯排序与筛选：田野研究、经济流动性及预测应用AI 解读

Decision-making often involves ranking and selection. For example, to assemble a team of political forecasters, we might begin by narrowing our choice set to the candidates we are confident rank among the top 10% in forecasting ability. Unfortunately, we do not know each candidate's true ability but observe a noisy estimate of it. This paper develops new Bayesian algorithms to rank and select candidates based on noisy estimates. Using simulations based on empirical data, we…

弱工具变量、第一阶段异方差、稳健 F 检验与基于第一阶段残差的 GMMAI 解读

This paper is concerned with the findings related to the robust first-stage F-statistic in the Monte Carlo analysis of Andrews (2018), who found in a heteroskedastic grouped-data design that even for very large values of the robust F-statistic, the standard 2SLS confidence intervals had large coverage distortions. This finding appears to discredit the robust F-statistic as a test for underidentification. However, it is shown here that large values of the robust F-statistic…

复杂纵向研究中的近端因果推断AI 解读

A standard assumption for causal inference about the joint effects of time-varying treatment is that one has measured sufficient covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values, also known as "sequential randomization assumption (SRA)". SRA is often criticized as it requires one to accurately measure all confounders. Realistically, measured covariates can rarely capture all confounders with certainty. Often…

高斯从属长程依赖过程的最优分块重抽样AI 解读

Block-based resampling estimators have been intensively investigated for weakly dependent time processes, which has helped to inform implementation (e.g., best block sizes). However, little is known about resampling performance and block sizes under strong or long-range dependence. To establish guideposts in block selection, we consider a broad class of strongly dependent time processes, formed by a transformation of a stationary long-memory Gaussian series, and examine…

混杂性结局依赖抽样下的双重稳健近端因果推断AI 解读

Unmeasured confounding and selection bias are often of concern in observational studies and may invalidate a causal analysis if not appropriately accounted for. Under outcome-dependent sampling, a latent factor that has causal effects on the treatment, outcome, and sample selection process may cause both unmeasured confounding and selection bias, rendering standard causal parameters unidentifiable without additional assumptions. Under an odds ratio model for the treatment…

融合机器学习的时变参数全球向量自回归：经济动态解释与预测AI 解读

The paper proposes a time-varying parameter global vector autoregressive (TVP-GVAR) framework for predicting and analysing developed region economic variables. We want to provide an easily accessible approach for the economy application settings, where a variety of machine learning models can be incorporated for out-of-sample prediction. The LASSO-type technique for numerically efficient model selection of mean squared errors (MSEs) is selected. We show the convincing…

因果推断方法的验证：Credence 生成式框架AI 解读

The fundamental challenge of drawing causal inference is that counterfactual outcomes are not fully observed for any unit. Furthermore, in observational studies, treatment assignment is likely to be confounded. Many statistical methods have emerged for causal inference under unconfoundedness conditions given pre-treatment covariates, including propensity score-based methods, prognostic score-based methods, and doubly robust methods. Unfortunately for applied researchers,…

劳动市场公平性度量中最小—最大估计量的识别与推断AI 解读

These notes shows how to do inference on the Demographic Parity (DP) metric. Although the metric is a complex statistic involving min and max computations, we propose a smooth approximation of those functions and derive its asymptotic distribution. The limit of these approximations and their gradients converge to those of the true max and min functions, wherever they exist. More importantly, when the true max and min functions are not differentiable, the approximations still…

结合自回归与得分驱动动态的时变排名模型AI 解读

We develop a new statistical model to analyse time-varying ranking data. The model can be used with a large number of ranked items, accommodates exogenous time-varying covariates and partial rankings, and is estimated via the maximum likelihood in a straightforward manner. Rankings are modelled using the Plackett-Luce distribution with time-varying worth parameters that follow a mean-reverting time series process. To capture the dependence of the worth parameters on past…

观察性比较效果研究中的工具变量、混杂调整与双重差分三角验证AI 解读

Observational studies can play a useful role in assessing the comparative effectiveness of competing treatments. In a clinical trial the randomization of participants to treatment and control groups generally results in well-balanced groups with respect to possible confounders, which makes the analysis straightforward. However, when analysing observational data, the potential for unmeasured confounding makes comparing treatment effects much more challenging. Causal inference…

通过重复测量加权聚合提高检验功效AI 解读

We present an aggregation scheme that increases power in randomized controlled trials and quasi-experiments when the intervention possesses a robust and well-articulated theory of change. Longitudinal data analyzing interventions often include multiple observations on individuals, some of which may be more likely to manifest a treatment effect than others. An intervention's theory of change provides guidance as to which of those observations are best situated to exhibit that…

存在不依从的序贯随机实验中的贝叶斯因果推断AI 解读

Scientific researchers utilize randomized experiments to draw casual statements. Most early studies as well as current work on experiments with sequential intervention decisions has been focusing on estimating the causal effects among sequential treatments, ignoring the non-compliance issues that experimental units might not be compliant with the treatment assignments that they were originally allocated. A series of methodologies have been developed to address the…

因果预测推断与目标试验模拟AI 解读

Causal inference from observational data can be viewed as a missing data problem arising from a hypothetical population-scale randomized trial matched to the observational study. This links a target trial protocol with a corresponding generative predictive model for inference, providing a complete framework for transparent communication of causal assumptions and statistical uncertainty on treatment effects, without the need for counterfactuals. The intuitive foundation for…