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聚类观察性数据中未测混杂下因果处理效应估计的敏感性分析AI 解读

Identifying causal treatment (or exposure) effects in observational studies requires the data to satisfy the unconfoundedness assumption which is not testable using the observed data. With sensitivity analysis, one can determine how the conclusions might change if assumptions are violated to a certain degree. In this paper, we propose a new technique for sensitivity analysis applicable to clusters observational data with a normally distributed or binary outcome. The proposed…

回归不连续设计中的视觉推断与图形呈现AI 解读

Despite the widespread use of graphs in empirical research, little is known about readers' ability to process the statistical information they are meant to convey ("visual inference"). We study visual inference within the context of regression discontinuity (RD) designs by measuring how accurately readers identify discontinuities in graphs produced from data generating processes calibrated on 11 published papers from leading economics journals. First, we assess the effects…

从自激与互激时间序列中发现因果图AI 解读

We present a generalized linear structural causal model, coupled with a novel data-adaptive linear regularization, to recover causal directed acyclic graphs (DAGs) from time series. By leveraging a recently developed stochastic monotone Variational Inequality (VI) formulation, we cast the causal discovery problem as a general convex optimization. Furthermore, we develop a non-asymptotic recovery guarantee and quantifiable uncertainty by solving a linear program to establish…

用于有效因果推断的卷积神经网络AI 解读

Convolutional neural networks (CNN) have been successful in machine learning applications. Their success relies on their ability to consider space invariant local features. We consider the use of CNN to fit nuisance models in semiparametric estimation of the average causal effect of a treatment. In this setting, nuisance models are functions of pre-treatment covariates that need to be controlled for. In an application where we want to estimate the effect of early retirement…

混合条件下多变量非参数模型的变化点检测与推断AI 解读

This paper studies multivariate nonparametric change point localization and inference problems. The data consists of a multivariate time series with potentially short range dependence. The distribution of this data is assumed to be piecewise constant with densities in a Hölder class. The change points, or times at which the distribution changes, are unknown. We derive the limiting distributions of the change point estimators when the minimal jump size vanishes or remains…

Ananke：基于图模型的因果推断 Python 软件包AI 解读

We implement Ananke: an object-oriented Python package for causal inference with graphical models. At the top of our inheritance structure is an easily extensible Graph class that provides an interface to several broadly useful graph-based algorithms and methods for visualization. We use best practices of object-oriented programming to implement subclasses of the Graph superclass that correspond to types of causal graphs that are popular in the current literature. This…

交互效应面板中的多重结构突变与量化宽松对银行放贷的影响AI 解读

This paper develops a new toolbox for multiple structural break detection in panel data models with interactive effects. The toolbox includes tests for the presence of structural breaks, a break date estimator, and a break date confidence interval. The new toolbox is applied to a large panel of US banks for a period characterized by massive quantitative easing programs aimed at lessening the impact of the global financial crisis and the COVID--19 pandemic. The question we…

存在隐含中介变量时的因果推断AI 解读

Proximal causal inference was recently proposed as a framework to identify causal effects from observational data in the presence of hidden confounders for which proxies are available. In this paper, we extend the proximal causal inference approach to settings where identification of causal effects hinges upon a set of mediators which are not observed, yet error prone proxies of the hidden mediators are measured. Specifically, (i) We establish causal hidden mediation…

双重稳健因果推断中的变量选择AI 解读

Confounding control is crucial and yet challenging for causal inference based on observational studies. Under the typical unconfoundness assumption, augmented inverse probability weighting (AIPW) has been popular for estimating the average causal effect (ACE) due to its double robustness in the sense it relies on either the propensity score model or the outcome mean model to be correctly specified. To ensure the key assumption holds, the effort is often made to collect a…

半参数双重稳健目标化双重机器学习综述AI 解读

In this review we cover the basics of efficient nonparametric parameter estimation (also called functional estimation), with a focus on parameters that arise in causal inference problems. We review both efficiency bounds (i.e., what is the best possible performance for estimating a given parameter?) and the analysis of particular estimators (i.e., what is this estimator's error, and does it attain the efficiency bound?) under weak assumptions. We emphasize minimax-style…

环境流行病学中因果暴露反应曲线的贝叶斯高斯过程估计AI 解读

Motivated by environmental policy questions, we address the challenges of estimation, change point detection, and uncertainty quantification of a causal exposure-response function (CERF). Under a potential outcome framework, the CERF describes the relationship between a continuously varying exposure (or treatment) and its causal effect on an outcome. We propose a new Bayesian approach that relies on a Gaussian process (GP) model to estimate the CERF nonparametrically. To…

边际结构模型中的自动化目标贝叶斯与目标最小损失估计推断AI 解读

Two of the principle tasks of causal inference are to define and estimate the effect of a treatment on an outcome of interest. Formally, such treatment effects are defined as a possibly functional summary of the data generating distribution, and are referred to as target parameters. Estimation of the target parameter can be difficult, especially when it is high-dimensional. Marginal Structural Models (MSMs) provide a way to summarize such target parameters in terms of a…

个体化处理效应估计中的对抗去混杂AI 解读

Observational studies have recently received significant attention from the machine learning community due to the increasingly available non-experimental observational data and the limitations of the experimental studies, such as considerable cost, impracticality, small and less representative sample sizes, etc. In observational studies, de-confounding is a fundamental problem of individualised treatment effects (ITE) estimation. This paper proposes disentangled…

因子结构结局研究中对未观测混杂的敏感性AI 解读

In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal conclusions beyond what can be achieved from analyzing individual outcomes in isolation. We argue that it is often reasonable to make a shared confounding assumption, under which residual dependence amongst outcomes can be used to simplify and…

针对零膨胀中介变量的新型因果中介分析方法AI 解读

Mediation analyses play important roles in making causal inference in biomedical research to examine causal pathways that may be mediated by one or more intermediate variables (i.e., mediators). Although mediation frameworks have been well established such as counterfactual-outcomes (i.e., potential-outcomes) models and traditional linear mediation models, little effort has been devoted to dealing with mediators with zero-inflated structures due to challenges associated with…

利用二元工具变量在未观测混杂下估计个体处理效应AI 解读

Estimating conditional average treatment effects (CATEs) from observational data is relevant in many fields such as personalized medicine. However, in practice, the treatment assignment is usually confounded by unobserved variables and thus introduces bias. A remedy to remove the bias is the use of instrumental variables (IVs). Such settings are widespread in medicine (e.g., trials where the treatment assignment is used as binary IV). In this paper, we propose a novel,…

混合随机化与断点设计的核回归分析AI 解读

Tie-breaker experimental designs are hybrids of Randomized Controlled Trials (RCTs) and Regression Discontinuity Designs (RDDs) in which subjects with moderate scores are placed in an RCT while subjects with extreme scores are deterministically assigned to the treatment or control group. In settings where it is unfair or uneconomical to deny the treatment to the more deserving recipients, the tie-breaker design (TBD) trades off the practical advantages of the RDD with the…

极端依赖与伴随次序统计量的关系AI 解读

The study of concomitants has recently met a renewed interest due to its applications in selection procedures. For instance, concomitants are used in ranked-set sampling, to achieve efficiency and reduce cost when compared to the simple random sampling. In parallel, the search for new methods to provide a rich description of extremal dependence among multiple time series has rapidly grown, due also to its numerous practical implications and the lack of suitable models to…

数据受限条件下的因果推断AI 解读

This dissertation focuses on modern causal inference under uncertainty and data restrictions, with applications to neoadjuvant clinical trials, distributed data networks, and robust individualized decision making. In the first project, we propose a method under the principal stratification framework to identify and estimate the average treatment effects on a binary outcome, conditional on the counterfactual status of a post-treatment intermediate response. Under mild…

协变量调整的对数秩检验：效率增益与广泛适用性AI 解读

Nonparametric covariate adjustment is considered for log-rank type tests of treatment effect with right-censored time-to-event data from clinical trials applying covariate-adaptive randomization. Our proposed covariate-adjusted log-rank test has a simple explicit formula and a guaranteed efficiency gain over the unadjusted test. We also show that our proposed test achieves universal applicability in the sense that the same formula of test can be universally applied to simple…

平均处理效应的回归调整插补估计量AI 解读

Imputing missing potential outcomes using an estimated regression function is a natural idea for estimating causal effects. In the literature, estimators that combine imputation and regression adjustments are believed to be comparable to augmented inverse probability weighting. Accordingly, people for a long time conjectured that such estimators, while avoiding directly constructing the weights, are also doubly robust (Imbens, 2004; Stuart, 2010). Generalizing an earlier…

稳定概率加权：有限重叠下多值处理异质性因果效应的估计与推断AI 解读

In this paper, I try to tame "Basu's elephants" (data with extreme selection on observables). I propose new practical large-sample and finite-sample methods for estimating and inferring heterogeneous causal effects (under unconfoundedness) in the empirically relevant context of limited overlap. I develop a general principle called "Stable Probability Weighting" (SPW) that can be used as an alternative to the widely used Inverse Probability Weighting (IPW) technique, which…

用于反事实估计的最优传输方法AI 解读

Many problems ask a question that can be formulated as a causal question: "what would have happened if...?" For example, "would the person have had surgery if he or she had been Black?" To address this kind of questions, calculating an average treatment effect (ATE) is often uninformative, because one would like to know how much impact a variable (such as skin color) has on a specific individual, characterized by certain covariates. Trying to calculate a conditional ATE…

事件时间结局的主分层分析AI 解读

Post-randomization events, also known as intercurrent events, such as treatment noncompliance and censoring due to a terminal event, are common in clinical trials. Principal stratification is a framework for causal inference in the presence of intercurrent events. Despite the extensive existing literature, there lacks generally applicable and accessible methods for principal stratification analysis with time-to-event outcomes. In this paper, we specify two causal estimands…