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Causal Inference with Invalid Instruments: Post-selection Problems and A Solution Using Searching and Sampling

无效工具变量下的因果推断:选择后问题与搜索、抽样解法

Instrumental variable methods are among the most commonly used causal inference approaches to deal with unmeasured confounders in observational studies. The presence of invalid instruments is the primary concern for practical applications, and a fast-growing area of research is inference for the causal effect with possibly invalid instruments. This paper illustrates that the existing confidence intervals may undercover when the valid and invalid instruments are hard to…

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Penalized Likelihood Inference with Survey Data

调查数据中的惩罚似然推断

This paper extends three Lasso inferential methods, Debiased Lasso, $C(α)$ and Selective Inference to a survey environment. We establish the asymptotic validity of the inference procedures in generalized linear models with survey weights and/or heteroskedasticity. Moreover, we generalize the methods to inference on nonlinear parameter functions e.g. the average marginal effect in survey logit models. We illustrate the effectiveness of the approach in simulated data and…

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Specification tests for generalized propensity scores using double projections

利用双重投影检验广义倾向得分模型的设定

This paper proposes a new class of nonparametric tests for the correct specification of models based on conditional moment restrictions, paying particular attention to generalized propensity score models. The test procedure is based on two different projection arguments, leading to test statistics that are suitable to setups with many covariates, and are (asymptotically) invariant to the estimation method used to estimate the nuisance parameters. We show that our proposed…

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Causal Structural Learning from Time Series: A Convex Optimization Approach

时间序列因果结构学习:一种凸优化方法

Structural learning, which aims to learn directed acyclic graphs (DAGs) from observational data, is foundational to causal reasoning and scientific discovery. Recent advancements formulate structural learning into a continuous optimization problem; however, DAG learning remains a highly non-convex problem, and there has not been much work on leveraging well-developed convex optimization techniques for causal structural learning. We fill this gap by proposing a data-adaptive…

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Marginal expected shortfall inference under multivariate regular variation

多元正则变动下边际期望损失的统计推断

Marginal expected shortfall is unquestionably one of the most popular systemic risk measures. Studying its extreme behaviour is particularly relevant for risk protection against severe global financial market downturns. In this context, results of statistical inference rely on the bivariate extreme values approach, disregarding the extremal dependence among a large number of financial institutions that make up the market. In order to take it into account we propose an…

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Improve Efficiency of Doubly Robust Estimator when Propensity Score is Misspecified

倾向评分误设时提高双重稳健估计的效率

Doubly robust (DR) estimation is a crucial technique in causal inference and missing data problems. We propose a novel Propensity score Augmentved Doubly robust (PAD) estimator to enhance the commonly used DR estimator for average treatment effect on the treated (ATT), or equivalently, the mean of the outcome under covariate shift. Our proposed estimator attains a lower asymptotic variance than the conventional DR estimator when the propensity score (PS) model is…

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Context-tree weighting for real-valued time series: Bayesian inference with hierarchical mixture models

实值时间序列的上下文树加权:层级混合模型的贝叶斯推断

Real-valued time series are ubiquitous in the sciences and engineering. In this work, a general, hierarchical Bayesian modelling framework is developed for building mixture models for times series. This development is based, in part, on the use of context trees, and it includes a collection of effective algorithmic tools for learning and inference. A discrete context (or 'state') is extracted for each sample, consisting of a discretised version of some of the most recent…

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Generalized Automatic Least Squares: Efficiency Gains from Misspecified Heteroscedasticity Models

广义自动最小二乘:异方差模型误设下的效率增益

It is well known that in the presence of heteroscedasticity ordinary least squares estimator is not efficient. I propose a generalized automatic least squares estimator (GALS) that makes partial correction of heteroscedasticity based on a (potentially) misspecified model without a pretest. Such an estimator is guaranteed to be at least as efficient as either OLS or WLS but can provide some asymptotic efficiency gains over OLS if the misspecified model is approximately…

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Testing for homogeneous treatment effects in linear and nonparametric instrumental variable models

线性与非参数工具变量模型中的处理效应同质性检验

The hypothesis of homogeneous treatment effects is central to the instrumental variables literature. This assumption signifies that treatment effects are constant across all subjects. It allows to interpret instrumental variable estimates as average treatment effects over the whole population of the study. When this assumption does not hold, the bias of instrumental variable estimators can be larger than that of naive estimators ignoring endogeneity. This paper develops two…

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Detection and Estimation of Structural Breaks in High-Dimensional Functional Time Series

高维函数型时间序列的结构突变检测与估计

In this paper, we consider detecting and estimating breaks in heterogeneous mean functions of high-dimensional functional time series which are allowed to be cross-sectionally correlated and temporally dependent. A new test statistic combining the functional CUSUM statistic and power enhancement component is proposed with asymptotic null distribution theory comparable to the conventional CUSUM theory derived for a single functional time series. In particular, the extra power…

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State space model multiple imputation for missing data in non-stationary multivariate time series with application in digital Psychiatry

非平稳多变量时间序列的状态空间多重填补及数字精神医学应用

Mobile technology enables unprecedented continuous monitoring of an individual's behavior, social interactions, symptoms, and other health conditions, presenting an enormous opportunity for therapeutic advancements and scientific discoveries regarding the etiology of psychiatric illness. Continuous collection of mobile data results in the generation of a new type of data: entangled multivariate time series of outcome, exposure, and covariates. Missing data is a pervasive…

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Bayesian Causal Inference in Doubly Gaussian DAG-probit Models

双组高斯 DAG-probit 模型中的贝叶斯因果推断

We consider modeling a binary response variable together with a set of covariates for two groups under observational data. The grouping variable can be the confounding variable (the common cause of treatment and outcome), gender, case/control, ethnicity, etc. Given the covariates and a binary latent variable, the goal is to construct two directed acyclic graphs (DAGs), while sharing some common parameters. The set of nodes, which represent the variables, are the same for…

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Estimating Marginal Treatment Effect in Cluster Randomized Trials with Multi-level Missing Outcomes

多层结局缺失下整群随机试验的边际处理效应估计

Analyses of cluster randomized trials (CRTs) can be complicated by informative missing outcome data. Methods such as inverse probability weighted generalized estimating equations have been proposed to account for informative missingness by weighting the observed individual outcome data in each cluster. These existing methods have focused on settings where missingness occurs at the individual level and each cluster has partially or fully observed individual outcomes. In the…

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Targeted Maximum Likelihood Based Estimation for Longitudinal Mediation Analysis

纵向中介分析的目标最大似然估计

Causal mediation analysis with random interventions has become an area of significant interest for understanding time-varying effects with longitudinal and survival outcomes. To tackle causal and statistical challenges due to the complex longitudinal data structure with time-varying confounders, competing risks, and informative censoring, there exists a general desire to combine machine learning techniques and semiparametric theory. In this manuscript, we focus on targeted…

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Estimation and Inference for High Dimensional Factor Model with Regime Switching

载荷状态切换的高维因子模型:估计与推断

This paper proposes maximum (quasi)likelihood estimation for high dimensional factor models with regime switching in the loadings. The model parameters are estimated jointly by the EM (expectation maximization) algorithm, which in the current context only requires iteratively calculating regime probabilities and principal components of the weighted sample covariance matrix. When regime dynamics are taken into account, smoothed regime probabilities are calculated using a…

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Linking a predictive model to causal effect estimation

将预测模型与因果效应估计相连接

A predictive model makes outcome predictions based on some given features, i.e., it estimates the conditional probability of the outcome given a feature vector. In general, a predictive model cannot estimate the causal effect of a feature on the outcome, i.e., how the outcome will change if the feature is changed while keeping the values of other features unchanged. This is because causal effect estimation requires interventional probabilities. However, many real world…

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Asymptotic expansion for batched bandits

批次式多臂老虎机的渐近展开

In bandit algorithms, the randomly time-varying adaptive experimental design makes it difficult to apply traditional limit theorems to off-policy evaluation of the treatment effect. Moreover, the normal approximation by the central limit theorem becomes unsatisfactory for lack of information due to the small sample size of the inferior arm. To resolve this issue, we introduce a backwards asymptotic expansion method and prove the validity of this scheme based on the partial…

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Causal Discovery with Score Matching on Additive Models with Arbitrary Noise

任意噪声加性模型中基于分数匹配的因果发现

Causal discovery methods are intrinsically constrained by the set of assumptions needed to ensure structure identifiability. Moreover additional restrictions are often imposed in order to simplify the inference task: this is the case for the Gaussian noise assumption on additive non-linear models, which is common to many causal discovery approaches. In this paper we show the shortcomings of inference under this hypothesis, analyzing the risk of edge inversion under violation…

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Independence weights for causal inference with continuous treatments

连续处理因果推断的独立性权重

Studying causal effects of continuous treatments is important for gaining a deeper understanding of many interventions, policies, or medications, yet researchers are often left with observational studies for doing so. In the observational setting, confounding is a barrier to the estimation of causal effects. Weighting approaches seek to control for confounding by reweighting samples so that confounders are comparable across different treatment values. Yet, for continuous…

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PStrata: An R Package for Principal Stratification

PStrata:用于主分层分析的 R 软件包

Post-treatment confounding is a common problem in causal inference, including special cases of noncompliance, truncation by death, surrogate endpoint, etc. Principal stratification (Frangakis and Rubin 2002) is a general framework for defining and estimating causal effects in the presence of post-treatment confounding. A prominent special case is the instrumental variable approach to noncompliance in randomized experiments (Angrist, Imbens, and Rubin 1996). Despite its…

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On the failure of the bootstrap for Chatterjee's rank correlation

Chatterjee 秩相关的 bootstrap 失效

While researchers commonly use the bootstrap for statistical inference, many of us have realized that the standard bootstrap, in general, does not work for Chatterjee's rank correlation. In this paper, we provide proof of this issue under an additional independence assumption, and complement our theory with simulation evidence for general settings. Chatterjee's rank correlation thus falls into a category of statistics that are asymptotically normal but bootstrap…

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A step towards the applicability of algorithms based on invariant causal learning on observational data

推进不变因果学习算法在观测数据中的应用

Machine learning can benefit from causal discovery for interpretation and from causal inference for generalization. In this line of research, a few invariant learning algorithms for out-of-distribution (OOD) generalization have been proposed by using multiple training environments to find invariant relationships. Some of them are focused on causal discovery as Invariant Causal Prediction (ICP), which finds causal parents of a variable of interest, and some directly provide a…

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A Bayesian Analysis of Two-Stage Randomized Experiments in the Presence of Interference, Treatment Nonadherence, and Missing Outcomes

存在干扰、不依从和结果缺失的两阶段随机实验贝叶斯分析

Three critical issues for causal inference that often occur in modern, complicated experiments are interference, treatment nonadherence, and missing outcomes. A great deal of research efforts has been dedicated to developing causal inferential methodologies that address these issues separately. However, methodologies that can address these issues simultaneously are lacking. We propose a Bayesian causal inference methodology to address this gap. Our methodology extends…

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Graphical Models of Entangled Missingness

纠缠缺失的图模型

Despite the growing interest in causal and statistical inference for settings with data dependence, few methods currently exist to account for missing data in dependent data settings; most classical missing data methods in statistics and causal inference treat data units as independent and identically distributed (i.i.d.). We develop a graphical modeling based framework for causal inference in the presence of entangled missingness, defined as missingness with data…

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