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Simulating data from marginal structural models for a survival time outcome

从生存结局边际结构模型生成模拟数据

Marginal structural models (MSMs) are often used to estimate causal effects of treatments on survival time outcomes from observational data when time-dependent confounding may be present. They can be fitted using, e.g., inverse probability of treatment weighting (IPTW). It is important to evaluate the performance of statistical methods in different scenarios, and simulation studies are a key tool for such evaluations. In such simulation studies, it is common to generate data…

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Minimax rates for heterogeneous causal effect estimation

异质性因果效应估计的极小极大收敛速率

Estimation of heterogeneous causal effects - i.e., how effects of policies and treatments vary across subjects - is a fundamental task in causal inference. Many methods for estimating conditional average treatment effects (CATEs) have been proposed in recent years, but questions surrounding optimality have remained largely unanswered. In particular, a minimax theory of optimality has yet to be developed, with the minimax rate of convergence and construction of rate-optimal…

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Piecewise monotone estimation in one-parameter exponential family

单参数指数族中的分段单调估计

The problem of estimating a piecewise monotone sequence of normal means is called the nearly isotonic regression. For this problem, an efficient algorithm has been devised by modifying the pool adjacent violators algorithm (PAVA). In this study, we investigate estimation of a piecewise monotone parameter sequence for general one-parameter exponential families such as binomial, Poisson and chi-square. We develop an efficient algorithm based on the modified PAVA, which…

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Exploring Distributions of House Prices and House Price Indices

房价与房价指数的分布探索

We use house prices (HP) and house price indices (HPI) as a proxy to income distribution. Specifically, we analyze sale prices in the 1970-2010 window of over 116,000 single-family homes in Hamilton County, Ohio, including Cincinnati metro area of about 2.2 million people. We also analyze HPI, published by Federal Housing Finance Agency (FHFA), for nearly 18,000 US ZIP codes that cover a period of over 40 years starting in 1980's. If HP can be viewed as a first derivative of…

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Evaluating individualized treatment effect predictions: a model-based perspective on discrimination and calibration assessment

个体化处理效应预测的评价:区分度与校准的模型视角

In recent years, there has been a growing interest in the prediction of individualized treatment effects. While there is a rapidly growing literature on the development of such models, there is little literature on the evaluation of their performance. In this paper, we aim to facilitate the validation of prediction models for individualized treatment effects. The estimands of interest are defined as based on the potential outcomes framework, which facilitates a comparison of…

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Particle Gibbs for Likelihood-Free Inference of State Space Models with Application to Stochastic Volatility

用于状态空间模型无似然推断的粒子 Gibbs 方法及随机波动率应用

State space models (SSMs) are widely used to describe dynamic systems. However, when the likelihood of the observations is intractable, parameter inference for SSMs cannot be easily carried out using standard Markov chain Monte Carlo or sequential Monte Carlo methods. In this paper, we propose a particle Gibbs sampler as a general strategy to handle SSMs with intractable likelihoods in the approximate Bayesian computation (ABC) setting. The proposed sampler incorporates a…

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Fair and Robust Estimation of Heterogeneous Treatment Effects for Policy Learning

面向政策学习的公平且稳健的异质处理效应估计

We propose a simple and general framework for nonparametric estimation of heterogeneous treatment effects under fairness constraints. Under standard regularity conditions, we show that the resulting estimators possess the double robustness property. We use this framework to characterize the trade-off between fairness and the maximum welfare achievable by the optimal policy. We evaluate the methods in a simulation study and illustrate them in a real-world case study.

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Finding Subgroups with Significant Treatment Effects

寻找具有显著处理效应的子群体

Researchers often run resource-intensive randomized controlled trials (RCTs) to estimate the causal effects of interventions on outcomes of interest. Yet these outcomes are often noisy, and estimated overall effects can be small or imprecise. Nevertheless, we may still be able to produce reliable evidence of the efficacy of an intervention by finding subgroups with significant effects. In this paper, we propose a machine-learning method that is specifically optimized for…

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Optimal Recovery for Causal Inference

用于因果推断的最优恢复

Problems in causal inference can be fruitfully addressed using signal processing techniques. As an example, it is crucial to successfully quantify the causal effects of an intervention to determine whether the intervention achieved desired outcomes. We present a new geometric signal processing approach to classical synthetic control called ellipsoidal optimal recovery (EOpR), for estimating the unobservable outcome of a treatment unit. EOpR provides policy evaluators with…

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Confidence and Uncertainty Assessment for Distributional Random Forests

分布随机森林的置信与不确定性评估

The Distributional Random Forest (DRF) is a recently introduced Random Forest algorithm to estimate multivariate conditional distributions. Due to its general estimation procedure, it can be employed to estimate a wide range of targets such as conditional average treatment effects, conditional quantiles, and conditional correlations. However, only results about the consistency and convergence rate of the DRF prediction are available so far. We characterize the asymptotic…

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Distribution Regression with Sample Selection, with an Application to Wage Decompositions in the UK

内生样本选择下的分布回归及英国工资分解

We develop a distribution regression model under endogenous sample selection. This model is a semi-parametric generalization of the Heckman selection model. It accommodates much richer effects of the covariates on outcome distribution and patterns of heterogeneity in the selection process, and allows for drastic departures from the Gaussian error structure, while maintaining the same level tractability as the classical model. The model applies to continuous, discrete and…

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Random multiplication versus random sum: auto-regressive-like models with integer-valued random inputs

随机乘法与随机求和:整数随机输入的类自回归模型

A common approach to analyze count time series is to fit models based on random sum operators. As an alternative, this paper introduces time series models based on a random multiplication operator, which is simply the multiplication of a variable operand by an integer-valued random coefficient, whose mean is the constant operand. Such operation is endowed into auto-regressive-like models with integer-valued random inputs, addressed as RMINAR. Two special variants are…

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A Random Effects Model-based Method of Moments Estimation of Causal Effect in Mendelian Randomization Studies

孟德尔随机化因果效应的随机效应模型矩估计

Recent advances in genotyping technology have delivered a wealth of genetic data, which is rapidly advancing our understanding of the underlying genetic architecture of complex diseases. Mendelian Randomization (MR) leverages such genetic data to estimate the causal effect of an exposure factor on an outcome from observational studies. In this paper, we utilize genetic correlations to summarize information on a large set of genetic variants associated with the exposure…

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Boundary Adaptive Local Polynomial Conditional Density Estimators

边界自适应的局部多项式条件密度估计

We begin by introducing a class of conditional density estimators based on local polynomial techniques. The estimators are boundary adaptive and easy to implement. We then study the (pointwise and) uniform statistical properties of the estimators, offering characterizations of both probability concentration and distributional approximation. In particular, we establish uniform convergence rates in probability and valid Gaussian distributional approximations for the…

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Margin-closed regime-switching multivariate time series models

边际封闭的状态切换多元时间序列模型

A regime-switching multivariate time series model which is closed under margins is built. The model imposes a restriction on all lower-dimensional sub-processes to follow a regime-switching process sharing the same latent regime sequence and having the same Markov order as the original process. The margin-closed regime-switching model is constructed by considering the multivariate margin-closed Gaussian VAR($k$) dependence as a copula within each regime, and builds…

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Some Finite-Sample Results on the Hausman Test

Hausman 检验的若干有限样本结果

This paper shows that the endogeneity test using the control function approach in linear instrumental variable models is a variant of the Hausman test. Moreover, we find that the test statistics used in these tests can be numerically ordered, indicating their relative power properties in finite samples.

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Uncertainty Quantification in Heterogeneous Treatment Effect Estimation with Gaussian-Process-Based Partially Linear Model

基于高斯过程部分线性模型的异质性处理效应不确定性量化

Estimating heterogeneous treatment effects across individuals has attracted growing attention as a statistical tool for performing critical decision-making. We propose a Bayesian inference framework that quantifies the uncertainty in treatment effect estimation to support decision-making in a relatively small sample size setting. Our proposed model places Gaussian process priors on the nonparametric components of a semiparametric model called a partially linear model. This…

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Debiased inference for a covariate-adjusted regression function

协变量调整回归函数的去偏推断

In this article, we study nonparametric inference for a covariate-adjusted regression function. This parameter captures the average association between a continuous exposure and an outcome after adjusting for other covariates. In particular, under certain causal conditions, this parameter corresponds to the average outcome had all units been assigned to a specific exposure level, known as the causal dose-response curve. We propose a debiased local linear estimator of the…

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Inferring Causality from Time Series data based on Structural Causal Model and its application to Neural Connectomics

基于结构因果模型的时间序列因果推断及其神经连接组应用

Inferring causation from time series data is of scientific interest in different disciplines, particularly in neural connectomics. While different approaches exist in the literature with parametric modeling assumptions, we focus on a non-parametric model for time series satisfying a Markovian structural causal model with stationary distribution and without concurrent effects. We show that the model structure can be used to its advantage to obtain an elegant algorithm for…

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Metastable Financial Markets

亚稳态金融市场

Metastability is a phenomenon observed in stochastic systems which stay in a false-equilibrium within a region of its state space until the occurrence of a sequence of rare events that leads to an abrupt transition to a different region. This paper presents financial markets as metastable systems and shows that, under this assumption, financial time series evolve as hidden Markov models. In special, we propose a theory that outlines an explicit causal relation between a…

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Inference on Optimal Dynamic Policies via Softmax Approximation

通过 Softmax 近似对最优动态政策进行推断

Estimating optimal dynamic policies from offline data is a fundamental problem in dynamic decision making. In the context of causal inference, the problem is known as estimating the optimal dynamic treatment regime. Even though there exists a plethora of methods for estimation, constructing confidence intervals for the value of the optimal regime and structural parameters associated with it is inherently harder, as it involves non-linear and non-differentiable functionals of…

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Standard errors for two-way clustering with serially correlated time effects

允许时间效应序列相关的双向聚类标准误

We propose improved standard errors and an asymptotic distribution theory for two-way clustered panels. Our proposed estimator and theory allow for arbitrary serial dependence in the common time effects, which is excluded by existing two-way methods, including the popular two-way cluster standard errors of Cameron, Gelbach, and Miller (2011) and the cluster bootstrap of Menzel (2021). Our asymptotic distribution theory is the first which allows for this level of…

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GMM-lev estimation and individual heterogeneity: Monte Carlo evidence and empirical applications

水平式 GMM 估计与个体异质性:蒙特卡洛证据及实证应用

We introduce a new estimator, CRE-GMM, which exploits the correlated random effects (CRE) approach within the generalised method of moments (GMM), specifically applied to level equations, GMM-lev. It has the advantage of estimating the effect of measurable time-invariant covariates using all available information. This is not possible with GMM-dif, applied to the equations of each period transformed into first differences, while GMM-sys uses little information as it adds the…

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Evaluating the Conservativeness of Robust Sandwich Variance Estimator in Weighted Average Treatment Effects

加权平均处理效应中稳健三明治方差估计的保守性评估

In causal inference, the Inverse Probability Weighting (IPW) estimator is commonly used to estimate causal effects for estimands within the class of Weighted Average Treatment Effect (WATE). When constructing confidence intervals (CIs), robust sandwich variance estimators are frequently used for practical reasons. Although these estimators are easy to calculate using widely-used statistical software, they often yield narrow CIs for commonly applied estimands, such as the…

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