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Interpretable Causal Inference for Analyzing Wearable, Sensor, and Distributional Data

可穿戴设备、传感器与分布型数据的可解释因果推断

Many modern causal questions ask how treatments affect complex outcomes that are measured using wearable devices and sensors. Current analysis approaches require summarizing these data into scalar statistics (e.g., the mean), but these summaries can be misleading. For example, disparate distributions can have the same means, variances, and other statistics. Researchers can overcome the loss of information by instead representing the data as distributions. We develop an…

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Forster-Warmuth Counterfactual Regression: A Unified Learning Approach

Forster–Warmuth 反事实回归:统一学习方法

Series or orthogonal basis regression is one of the most popular non-parametric regression techniques in practice, obtained by regressing the response on features generated by evaluating the basis functions at observed covariate values. The most routinely used series estimator is based on ordinary least squares fitting, which is known to be minimax rate optimal in various settings, albeit under stringent restrictions on the basis functions and the distribution of covariates.…

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Data integration methods for micro-randomized trials

微随机试验的数据整合方法

Existing statistical methods for the analysis of micro-randomized trials (MRTs) are designed to estimate causal excursion effects using data from a single MRT. In practice, however, researchers can often find previous MRTs that employ similar interventions. In this paper, we develop data integration methods that capitalize on this additional information, leading to statistical efficiency gains. To further increase efficiency, we demonstrate how to combine these approaches…

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Robust Inference in Locally Misspecified Bipartite Networks

局部误设双部网络中的稳健推断

This paper introduces a methodology to conduct robust inference in bipartite networks under local misspecification. We focus on a class of dyadic network models with misspecified conditional moment restrictions. The framework of misspecification is local, as the effect of misspecification varies with the sample size. We utilize this local asymptotic approach to construct a robust estimator that is minimax optimal for the mean square error within a neighborhood of…

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Adaptive estimation for Weakly Dependent Functional Times Series

弱依赖函数型时间序列的自适应估计

The local regularity of functional time series is studied under $L^p-m-$appro\-ximability assumptions. The sample paths are observed with error at possibly random design points. Non-asymptotic concentration bounds of the regularity estimators are derived. As an application, we build nonparametric mean and autocovariance functions estimators that adapt to the regularity and the design, which can be sparse or dense. We also derive the asymptotic normality of the mean…

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kDGLM: a R package for Bayesian analysis of Generalized Dynamic Linear Models

kDGLM:广义动态线性模型贝叶斯分析的 R 包

This paper introduces kDGLM, an R package designed for Bayesian analysis of Generalized Dynamic Linear Models (GDLM), with a primary focus on both uni- and multivariate exponential families. Emphasizing sequential inference for time series data, the kDGLM package provides comprehensive support for fitting, smoothing, monitoring, and feed-forward interventions. The methodology employed by kDGLM, as proposed in Alves et al. (2024), seamlessly integrates with well-established…

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On the use of the cumulant generating function for inference on time series

利用累积量生成函数进行时间序列推断

We introduce innovative inference procedures for analyzing time series data. Our methodology enables density approximation and composite hypothesis testing based on Whittle's estimator, a widely applied M-estimator in the frequency domain. Its core feature involves the (general Legendre transform of the) cumulant generating function of the Whittle likelihood score, as obtained using an approximated distribution of the periodogram ordinates. We present a testing algorithm…

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A Bayesian multilevel hidden Markov model with Poisson-lognormal emissions for intense longitudinal count data

密集纵向计数数据的贝叶斯多层泊松对数正态隐马尔可夫模型

Hidden Markov models (HMMs) are probabilistic methods in which observations are seen as realizations of a latent Markov process with discrete states that switch over time. Moving beyond standard statistical tests, HMMs offer a statistical environment to optimally exploit the information present in multivariate time series, uncovering the latent dynamics that rule them. Here, we extend the Poisson HMM to the multilevel framework, accommodating variability between individuals…

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A modified debiased inverse-variance weighted estimator in two-sample summary-data Mendelian randomization

两样本汇总数据孟德尔随机化中的修正去偏逆方差加权估计

Mendelian randomization uses genetic variants as instrumental variables to make causal inferences about the effects of modifiable risk factors on diseases from observational data. One of the major challenges in Mendelian randomization is that many genetic variants are only modestly or even weakly associated with the risk factor of interest, a setting known as many weak instruments. Many existing methods, such as the popular inverse-variance weighted (IVW) method, could be…

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ODE Discovery for Longitudinal Heterogeneous Treatment Effects Inference

用于纵向异质性处理效应推断的常微分方程发现

Inferring unbiased treatment effects has received widespread attention in the machine learning community. In recent years, our community has proposed numerous solutions in standard settings, high-dimensional treatment settings, and even longitudinal settings. While very diverse, the solution has mostly relied on neural networks for inference and simultaneous correction of assignment bias. New approaches typically build on top of previous approaches by proposing new (or…

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Assessing Delayed Treatment Benefits of Immunotherapy Using Long-Term Average Hazard: A Novel Test/Estimation Approach

用长期平均风险评估免疫治疗的延迟获益

Delayed treatment effects on time-to-event outcomes have often been observed in randomized controlled studies of cancer immunotherapies. In the case of delayed onset of treatment effect, the conventional test/estimation approach using the log-rank test for between-group comparison and Cox's hazard ratio to estimate the magnitude of treatment effect is not optimal, because the log-rank test is not the most powerful option, and the interpretation of the resulting hazard ratio…

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Limits of Approximating the Median Treatment Effect

中位数处理效应的近似极限

Average Treatment Effect (ATE) estimation is a well-studied problem in causal inference. However, it does not necessarily capture the heterogeneity in the data, and several approaches have been proposed to tackle the issue, including estimating the Quantile Treatment Effects. In the finite population setting containing $n$ individuals, with treatment and control values denoted by the potential outcome vectors $\mathbf{a}, \mathbf{b}$, much of the prior work focused on…

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Self-Compatibility: Evaluating Causal Discovery without Ground Truth

自兼容性:在没有真实因果结构时评估因果发现

As causal ground truth is incredibly rare, causal discovery algorithms are commonly only evaluated on simulated data. This is concerning, given that simulations reflect preconceptions about generating processes regarding noise distributions, model classes, and more. In this work, we propose a novel method for falsifying the output of a causal discovery algorithm in the absence of ground truth. Our key insight is that while statistical learning seeks stability across subsets…

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On the Time-Varying Structure of the Arbitrage Pricing Theory using the Japanese Sector Indices

基于日本行业指数的套利定价理论时变结构研究

This paper is the first study to examine the time instability of the APT in the Japanese stock market. In particular, we measure how changes in each risk factor affect the stock risk premiums to investigate the validity of the APT over time, applying the rolling window method to Fama and MacBeth's (1973) two-step regression and Kamstra and Shi's (2023) generalized GRS test. We summarize our empirical results as follows: (1) the changes in monetary policy by major central…

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Automatic Debiased Machine Learning via Riesz Regression

通过 Riesz 回归实现自动去偏机器学习

A variety of interesting parameters may depend on high dimensional regressions. Machine learning can be used to estimate such parameters. However estimators based on machine learners can be severely biased by regularization and/or model selection. Debiased machine learning uses Neyman orthogonal estimating equations to reduce such biases. Debiased machine learning generally requires estimation of unknown Riesz representers. A primary innovation of this paper is to provide…

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Recurrent Events Modeling Based on a Reflected Brownian Motion with Application to Hypoglycemia

基于反射布朗运动的重复事件模型及其低血糖应用

Patients with type 2 diabetes need to closely monitor blood sugar levels as their routine diabetes self-management. Although many treatment agents aim to tightly control blood sugar, hypoglycemia often stands as an adverse event. In practice, patients can observe hypoglycemic events more easily than hyperglycemic events due to the perception of neurogenic symptoms. We propose to model each patient's observed hypoglycemic event as a lower-boundary crossing event for a…

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Reducing Marketplace Interference Bias Via Shadow Prices

利用影子价格降低交易平台的市场干扰偏差

Marketplace companies rely heavily on experimentation when making changes to the design or operation of their platforms. The workhorse of experimentation is the randomized controlled trial (RCT), or A/B test, in which users are randomly assigned to treatment or control groups. However, marketplace interference causes the Stable Unit Treatment Value Assumption (SUTVA) to be violated, leading to bias in the standard RCT metric. In this work, we propose techniques for platforms…

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Time-uniform central limit theory and asymptotic confidence sequences

时间一致的中心极限定理与渐近置信序列

Confidence intervals based on the central limit theorem (CLT) are a cornerstone of classical statistics. Despite being only asymptotically valid, they are ubiquitous because they permit statistical inference under weak assumptions and can often be applied to problems even when nonasymptotic inference is impossible. This paper introduces time-uniform analogues of such asymptotic confidence intervals, adding to the literature on confidence sequences (CS) -- sequences of…

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Reweighting the RCT for generalization: finite sample error and variable selection

随机试验重加权推广:有限样本误差与变量选择

Randomized Controlled Trials (RCTs) may suffer from limited scope. In particular, samples may be unrepresentative: some RCTs over- or under- sample individuals with certain characteristics compared to the target population, for which one wants conclusions on treatment effectiveness. Re-weighting trial individuals to match the target population can improve the treatment effect estimation. In this work, we establish the exact expressions of the bias and variance of such…

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Survey calibration for causal inference: a simple method to balance covariate distributions

用于因果推断的调查校准:协变量分布平衡的简便方法

This paper proposes a~simple, yet powerful, method for balancing distributions of covariates for causal inference based on observational studies. The method makes it possible to balance an arbitrary number of quantiles (e.g., medians, quartiles, or deciles) together with means if necessary. The proposed approach is based on the theory of calibration estimators (Deville and Särndal 1992), in particular, calibration estimators for quantiles, proposed by Harms and Duchesne…

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A Two-Stage Feature Selection Approach for Robust Evaluation of Treatment Effects in High-Dimensional Observational Data

高维观察数据中稳健处理效应评估的两阶段特征选择

A Randomized Control Trial (RCT) is considered as the gold standard for evaluating the effect of any intervention or treatment. However, its feasibility is often hindered by ethical, economical, and legal considerations, making observational data a valuable alternative for drawing causal conclusions. Nevertheless, healthcare observational data presents a difficult challenge due to its high dimensionality, requiring careful consideration to ensure unbiased, reliable, and…

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Bayesian Analysis of High Dimensional Vector Error Correction Model

高维向量误差修正模型的贝叶斯分析

Vector Error Correction Model (VECM) is a classic method to analyse cointegration relationships amongst multivariate non-stationary time series. In this paper, we focus on high dimensional setting and seek for sample-size-efficient methodology to determine the level of cointegration. Our investigation centres at a Bayesian approach to analyse the cointegration matrix, henceforth determining the cointegration rank. We design two algorithms and implement them on simulated…

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Empirical study of periodic autoregressive models with additive noise -- estimation and testing

带加性噪声的周期自回归模型:估计与检验的实证研究

Periodic autoregressive (PAR) time series with finite variance is considered as one of the most common models of second-order cyclostationary processes. However, in the real applications, the signals with periodic characteristics may be disturbed by additional noise related to measurement device disturbances or to other external sources. Thus, the known estimation techniques dedicated for PAR models may be inefficient for such cases. When the variance of the additive noise…

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Sample Splitting and Assessing Goodness-of-fit of Time Series

样本分割与时间序列拟合优度评估

A fundamental and often final step in time series modeling is to assess the quality of fit of a proposed model to the data. Since the underlying distribution of the innovations that generate a model is often not prescribed, goodness-of-fit tests typically take the form of testing the fitted residuals for serial independence. However, these fitted residuals are inherently dependent since they are based on the same parameter estimates and thus standard tests of serial…

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