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Combining experimental and observational data through a power likelihood

通过幂似然结合实验与观察数据

Randomized controlled trials are the gold standard for causal inference and play a pivotal role in modern evidence-based medicine. However, the sample sizes they use are often too limited to draw significant causal conclusions for subgroups that are less prevalent in the population. In contrast, observational data are becoming increasingly accessible in large volumes but can be subject to bias as a result of hidden confounding. Given these complementary features, we propose…

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Dropout Regularization Versus $\ell_2$-Penalization in the Linear Model

线性模型中 Dropout 正则化与 ℓ2 惩罚的比较

We investigate the statistical behavior of gradient descent iterates with dropout in the linear regression model. In particular, non-asymptotic bounds for the convergence of expectations and covariance matrices of the iterates are derived. The results shed more light on the widely cited connection between dropout and l2-regularization in the linear model. We indicate a more subtle relationship, owing to interactions between the gradient descent dynamics and the additional…

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Differentially Private Federated Learning: Servers Trustworthiness, Estimation, and Statistical Inference

差分隐私联邦学习:服务器可信性、估计与统计推断

Differentially private federated learning is crucial for maintaining privacy in distributed environments. This paper investigates the challenges of high-dimensional estimation and inference under the constraints of differential privacy. First, we study scenarios involving an untrusted central server, demonstrating the inherent difficulties of accurate estimation in high-dimensional problems. Our findings indicate that the tight minimax rates depends on the…

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Empirical Bayes inference in sparse high-dimensional generalized linear models

稀疏高维广义线性模型中的经验贝叶斯推断

High-dimensional linear models have been widely studied, but the developments in high-dimensional generalized linear models, or GLMs, have been slower. In this paper, we propose an empirical or data-driven prior leading to an empirical Bayes posterior distribution which can be used for estimation of and inference on the coefficient vector in a high-dimensional GLM, as well as for variable selection. We prove that our proposed posterior concentrates around the true/sparse…

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Unlocking Insights: Enhanced Analysis of Covariance in General Factorial Designs through Multiple Contrast Tests under Variance Heteroscedasticity

异方差下一般析因设计的协方差分析:多重对比检验

A common goal in clinical trials is to conduct tests on estimated treatment effects adjusted for covariates such as age or sex. Analysis of Covariance (ANCOVA) is often used in these scenarios to test the global null hypothesis of no treatment effect using an $F$-test. However, in several samples, the $F$-test does not provide any information about individual null hypotheses and has strict assumptions such as variance homoscedasticity. We extend the method proposed by…

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Model-free controlled variable selection via data splitting

基于数据分割的无模型控制变量选择

Addressing the simultaneous identification of contributory variables while controlling the false discovery rate (FDR) in high-dimensional data is a crucial statistical challenge. In this paper, we propose a novel model-free variable selection procedure in sufficient dimension reduction framework via a data splitting technique. The variable selection problem is first converted to a least squares procedure with several response transformations. We construct a series of…

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Inference for multiple change-points in generalized integer-valued autoregressive model

广义整数值自回归模型的多变点推断

In this paper, we propose a computationally valid and theoretically justified methods, the likelihood ratio scan method (LRSM), for estimating multiple change-points in a piecewise stationary generalized conditional integer-valued autoregressive process. LRSM with the usual window parameter $h$ is more satisfied to be used in long-time series with few and even change-points vs. LRSM with the multiple window parameter $h_{mix}$ performs well in short-time series with large…

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Change-point analysis for binomial autoregressive model with application to price stability counts

二项自回归模型的变点分析及价格稳定计数应用

The first-order binomial autoregressive (BAR(1)) model is the most frequently used tool to analyze the bounded count time series. The BAR(1) model is stationary and assumes process parameters to remain constant throughout the time period, which may be incompatible with the non-stationary real data, which indicates piecewise stationary characteristic. To better analyze the non-stationary bounded count time series, this article introduces the BAR(1) process with multiple…

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Inference of Causal Networks using a Topological Threshold

利用拓扑阈值推断因果网络

We propose a constraint-based algorithm, which automatically determines causal relevance thresholds, to infer causal networks from data. We call these topological thresholds. We present two methods for determining the threshold: the first seeks a set of edges that leaves no disconnected nodes in the network; the second seeks a causal large connected component in the data. We tested these methods both for discrete synthetic and real data, and compared the results with those…

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Estimating Conditional Value-at-Risk with Nonstationary Quantile Predictive Regression Models

利用非平稳分位数预测回归估计条件风险价值

This paper develops an asymptotic distribution theory for an endogenous instrumentation approach in quantile predictive regressions when both generated covariates and persistent predictors are used. The generated covariates are obtained from an auxiliary quantile predictive regression model and the statistical problem of interest is the robust estimation and inference of the parameters that correspond to the primary quantile predictive regression in which this generated…

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Corrected generalized cross-validation for finite ensembles of penalized estimators

有限惩罚估计器集成下的修正广义交叉验证

Generalized cross-validation (GCV) is a widely-used method for estimating the squared out-of-sample prediction risk that employs a scalar degrees of freedom adjustment (in a multiplicative sense) to the squared training error. In this paper, we examine the consistency of GCV for estimating the prediction risk of arbitrary ensembles of penalized least-squares estimators. We show that GCV is inconsistent for any finite ensemble of size greater than one. Towards repairing this…

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Statistical Inference for Heterogeneous Treatment Effects Discovered by Generic Machine Learning in Randomized Experiments

随机实验中通用机器学习发现的异质性处理效应:统计推断

Researchers are increasingly turning to machine learning (ML) algorithms to investigate causal heterogeneity in randomized experiments. Despite their promise, ML algorithms may fail to accurately ascertain heterogeneous treatment effects under practical settings with many covariates and small sample size. In addition, the quantification of estimation uncertainty remains a challenge. We develop a general approach to statistical inference for heterogeneous treatment effects…

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lmw: Linear Model Weights for Causal Inference

lmw:用于因果推断的线性模型权重

The linear regression model is widely used in the biomedical and social sciences as well as in policy and business research to adjust for covariates and estimate the average effects of treatments. Behind every causal inference endeavor there is a hypothetical randomized experiment. However, in routine regression analyses in observational studies, it is unclear how well the adjustments made by regression approximate key features of randomized experiments, such as covariate…

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Selection of the Most Probable Best

最可能最优方案的选择

We consider an expected-value ranking and selection (R&S) problem where all k solutions' simulation outputs depend on a common parameter whose uncertainty can be modeled by a distribution. We define the most probable best (MPB) to be the solution that has the largest probability of being optimal with respect to the distribution and design an efficient sequential sampling algorithm to learn the MPB when the parameter has a finite support. We derive the large deviations rate…

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Difference-in-Differences under Bipartite Network Interference: A Framework for Quasi-Experimental Assessment of the Effects of Environmental Policies on Health

二部网络干扰下的双重差分:环境政策健康效应的准实验评估

Pollution from coal-fired power plants has been linked to substantial health and mortality burdens in the US. In recent decades, federal regulatory policies have spurred efforts to curb emissions through various actions, such as the installation of emissions control technologies on power plants. However, assessing the health impacts of these measures, particularly over longer periods of time, is complicated by several factors. First, the units that potentially receive the…

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Graphical criteria for the identification of marginal causal effects in continuous-time survival and event-history analyses

连续时间生存与事件史分析中边际因果效应识别的图准则

We consider continuous-time survival or more general event-history settings, where the aim is to infer the causal effect of a time-dependent treatment process. This is formalised as the effect on the outcome event of a (possibly hypothetical) intervention on the intensity of the treatment process, i.e. a stochastic intervention. To establish whether valid inference about the interventional situation can be drawn from typical observational, i.e. non-experimental, data we…

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Prior Effective Sample Size When Borrowing on the Treatment Effect Scale

在治疗效应尺度借用外部信息时的先验有效样本量

With the robust uptick in the applications of Bayesian external data borrowing, eliciting a prior distribution with the proper amount of information becomes increasingly critical. The prior effective sample size (ESS) is an intuitive and efficient measure for this purpose. The majority of ESS definitions have been proposed in the context of borrowing control information. While many Bayesian models can be naturally extended to leveraging external information on the treatment…

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Efficient Integrated Volatility Estimation in the Presence of Infinite Variation Jumps via Debiased Truncated Realized Variations

通过去偏截断已实现变差有效估计无限变差跳跃下的积分波动率

Statistical inference for stochastic processes based on high-frequency observations has been an active research area for more than two decades. One of the most well-known and widely studied problems has been the estimation of the quadratic variation of the continuous component of an Itô semimartingale with jumps. Several rate- and variance-efficient estimators have been proposed in the literature when the jump component is of bounded variation. However, to date, very few…

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Extrapolation and generative algorithms for three applications in finance

外推与生成算法在三个金融问题中的应用

For three applications of central interest in finance, we demonstrate the relevance of numerical algorithms based on reproducing kernel Hilbert space (RKHS) techniques. Three use cases are investigated. First, we show that extrapolating from few pricer examples leads to sufficiently accurate and computationally efficient results so that our algorithm can serve as a pricing framework. The second use case concerns reverse stress testing, which is formulated as an inversion…

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Estimating weak periodic vector autoregressive time series

弱周期向量自回归时间序列的估计

This article develops the asymptotic distribution of the least squares estimator of the model parameters in periodicvector autoregressive time series models (hereafter PVAR) with uncorrelated but dependent innovations. When theinnovations are dependent, this asymptotic distributions can be quite different from that of PVAR models with in-dependent and identically distributed (iid for short) innovations developed in Ursu and Duchesne (2009). Modifiedversions of the Wald tests…

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Marginal Analysis of Count Time Series in the Presence of Missing Observations

存在缺失观测时计数时间序列的边际分析

Time series in real-world applications often have missing observations, making typical analytical methods unsuitable. One method for dealing with missing data is the concept of amplitude modulation. While this principle works with any data, here, missing data for unbounded and bounded count time series are investigated, where tailor-made dispersion and skewness statistics are used for model diagnostics. General closed-form asymptotic formulas are derived for such statistics…

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Detection of a structural break in intraday volatility pattern

日内波动率模式的结构突变检测

We develop theory leading to testing procedures for the presence of a change point in the intraday volatility pattern. The new theory is developed in the framework of Functional Data Analysis. It is based on a model akin to the stochastic volatility model for scalar point-to-point returns. In our context, we study intraday curves, one curve per trading day. After postulating a suitable model for such functional data, we present three tests focusing, respectively, on changes…

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Propensity Score Analysis with Guaranteed Subgroup Balance

保证亚组平衡的倾向得分分析

Estimating the causal treatment effects by subgroups is important in observational studies when the treatment effect heterogeneity may be present. Existing propensity score methods rely on a correctly specified propensity score model. Model misspecification results in biased treatment effect estimation and covariate imbalance. We proposed a new algorithm, the propensity score analysis with guaranteed subgroup balance (G-SBPS), to achieve covariate mean balance in all…

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Improved bounds and inference on optimal regimes

最优治疗策略的改进界限与推断

Point identification of causal effects requires strong assumptions that are unreasonable in many practical settings. However, informative bounds on these effects can often be derived under plausible assumptions. Even when these bounds are wide or cover null effects, they can guide practical decisions based on formal decision theoretic criteria. Here we derive new results on optimal treatment regimes in settings where the effect of interest is bounded. These results are…

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