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Structured prior distributions for the covariance matrix in latent factor models

潜在因子模型协方差矩阵的结构化先验

Factor models are widely used for dimension reduction in the analysis of multivariate data. This is achieved through decomposition of a p x p covariance matrix into the sum of two components. Through a latent factor representation, they can be interpreted as a diagonal matrix of idiosyncratic variances and a shared variation matrix, that is, the product of a p x k factor loadings matrix and its transpose. If k << p, this defines a parsimonious factorisation of the covariance…

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Design-based theory for Lasso adjustment in randomized block experiments and rerandomized experiments

随机区组与再随机化实验中 Lasso 调整的设计型理论

Blocking, a special case of rerandomization, is routinely implemented in the design stage of randomized experiments to balance the baseline covariates. This study proposes a regression adjustment method based on the least absolute shrinkage and selection operator (Lasso) to efficiently estimate the average treatment effect in randomized block experiments with high-dimensional covariates. We derive the asymptotic properties of the proposed estimator and outline the conditions…

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On Counterfactual Interventions in Vector Autoregressive Models

向量自回归模型中的反事实干预

Counterfactual reasoning allows us to explore hypothetical scenarios in order to explain the impacts of our decisions. However, addressing such inquires is impossible without establishing the appropriate mathematical framework. In this work, we introduce the problem of counterfactual reasoning in the context of vector autoregressive (VAR) processes. We also formulate the inference of a causal model as a joint regression task where for inference we use both data with and…

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Improving Finite Sample Performance of Causal Discovery by Exploiting Temporal Structure

利用时间结构改善因果发现的有限样本表现

Methods of causal discovery aim to identify causal structures in a data driven way. Existing algorithms are known to be unstable and sensitive to statistical errors, and are therefore rarely used with biomedical or epidemiological data. We present an algorithm that efficiently exploits temporal structure, so-called tiered background knowledge, for estimating causal structures. Tiered background knowledge is readily available from, e.g., cohort or registry data. When used…

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Functional knockoffs selection with applications to functional data analysis in high dimensions

高维函数型数据分析中的函数型 knockoffs 变量选择

The knockoffs is a recently proposed powerful framework that effectively controls the false discovery rate (FDR) for variable selection. However, none of the existing knockoff solutions are directly suited to handle multivariate or high-dimensional functional data, which has become increasingly prevalent in various scientific applications. In this paper, we propose a novel functional model-X knockoffs selection framework tailored to sparse high-dimensional functional models,…

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Asymptotic equivalence of Principal Components and Quasi Maximum Likelihood estimators in Large Approximate Factor Models

大型近似因子模型中主成分与拟极大似然估计的渐近等价性

This paper investigates the properties of Quasi Maximum Likelihood estimation of an approximate factor model for an $n$-dimensional vector of stationary time series. We prove that the factor loadings estimated by Quasi Maximum Likelihood are asymptotically equivalent, as $n\to\infty$, to those estimated via Principal Components. Both estimators are, in turn, also asymptotically equivalent, as $n\to\infty$, to the unfeasible Ordinary Least Squares estimator we would have if…

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Cutting Feedback in Misspecified Copula Models

错设 Copula 模型中的反馈切断

In copula models the marginal distributions and copula function are specified separately. We treat these as two modules in a modular Bayesian inference framework, and propose conducting modified Bayesian inference by "cutting feedback". Cutting feedback limits the influence of potentially misspecified modules in posterior inference. We consider two types of cuts. The first limits the influence of a misspecified copula on inference for the marginals, which is a Bayesian…

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Bayesian Hierarchical Modeling and Inference for Mechanistic Systems in Industrial Hygiene

工业卫生中机理系统的贝叶斯分层建模与推断

A series of experiments in stationary and moving passenger rail cars were conducted to measure removal rates of particles in the size ranges of SARS-CoV-2 viral aerosols, and the air changes per hour provided by existing and modified air handling systems. Such methods for exposure assessments are customarily based on mechanistic models derived from physical laws of particle movement that are deterministic and do not account for measurement errors inherent in data collection.…

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Shrinkage MMSE estimators of covariances beyond the zero-mean and stationary variance assumptions

超越零均值与平稳方差假设的协方差收缩MMSE估计

We tackle covariance estimation in low-sample scenarios, employing a structured covariance matrix with shrinkage methods. These involve convexly combining a low-bias/high-variance empirical estimate with a biased regularization estimator, striking a bias-variance trade-off. Literature provides optimal settings of the regularization amount through risk minimization between the true covariance and its shrunk counterpart. Such estimators were derived for zero-mean statistics…

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Manipulation Test for Multidimensional RDD

多维回归不连续设计的操纵检验

The causal inference model proposed by Lee (2008) for the regression discontinuity design (RDD) relies on assumptions that imply the continuity of the density of the assignment (running) variable. The test for this implication is commonly referred to as the manipulation test and is regularly reported in applied research to strengthen the design's validity. The multidimensional RDD (MRDD) extends the RDD to contexts where treatment assignment depends on several running…

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Inference in Experiments with Matched Pairs and Imperfect Compliance

配对随机实验与不完全依从下的统计推断

This paper studies inference for the local average treatment effect in randomized controlled trials with imperfect compliance where treatment status is determined according to "matched pairs." By "matched pairs," we mean that units are sampled i.i.d. from the population of interest, paired according to observed, baseline covariates and finally, within each pair, one unit is selected at random for treatment. Under weak assumptions governing the quality of the pairings, we…

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Sub-Gaussian High-Dimensional Covariance Matrix Estimation under Elliptical Factor Model with 2 + εth Moment

具有 2+ε 阶矩的椭圆因子模型下高维协方差矩阵的次高斯率估计

We study the estimation of high-dimensional covariance matrices under elliptical factor models with 2 + εth moment. For such heavy-tailed data, robust estimators like the Huber-type estimator in Fan, Liu and Wang (2018) can not achieve sub-Gaussian convergence rate. In this paper, we develop an idiosyncratic-projected self-normalization (IPSN) method to remove the effect of heavy-tailed scalar parameter, and propose a robust pilot estimator for the scatter matrix that…

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Asymptotic Uncertainty in the Estimation of Frequency Domain Causal Effects for Linear Processes

线性过程频域因果效应估计的渐近不确定性

Structural vector autoregressive (SVAR) processes are commonly used time series models to identify and quantify causal interactions between dynamically interacting processes from observational data. The causal relationships between these processes can be effectively represented by a finite directed process graph - a graph that connects two processes whenever there is a direct delayed or simultaneous effect between them. Recent research has introduced a framework for…

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Causal Responder Detection

因果响应者检测

We introduce the causal responders detection (CARD), a novel method for responder analysis that identifies treated subjects who significantly respond to a treatment. Leveraging recent advances in conformal prediction, CARD employs machine learning techniques to accurately identify responders while controlling the false discovery rate in finite sample sizes. Additionally, we incorporate a propensity score adjustment to mitigate bias arising from non-random treatment…

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Transfer Learning for High Dimensional Robust Regression

高维稳健回归中的迁移学习

Transfer learning has become an essential technique for utilizing information from source datasets to improve the performance of the target task. However, in the context of high-dimensional data, heterogeneity arises due to heteroscedastic variance or inhomogeneous covariate effects. To solve this problem, this paper proposes a robust transfer learning based on the Huber regression, specifically designed for scenarios where the transferable source data set is known. This…

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Practical identifiability and parameter estimation of compartmental epidemiological models

分舱流行病模型的实际可识别性与参数估计

Practical parameter identifiability in ODE-based epidemiological models is a known issue, yet one that merits further study. It is essentially ubiquitous due to noise and errors in real data. In this study, to avoid uncertainty stemming from data of unknown quality, simulated data with added noise are used to investigate practical identifiability in two distinct epidemiological models. Particular emphasis is placed on the role of initial conditions, which are assumed…

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Two-Stage Testing in a high dimensional setting

高维设定下的两阶段检验

In a high dimensional regression setting in which the number of variables ($p$) is much larger than the sample size ($n$), the number of possible two-way interactions between the variables is immense. If the number of variables is in the order of one million, which is usually the case in e.g., genetics, the number of two-way interactions is of the order one million squared. In the pursuit of detecting two-way interactions, testing all pairs for interactions one-by-one is…

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The Influence of Nuisance Parameter Uncertainty on Statistical Inference in Practical Data Science Models

干扰参数不确定性对实用数据科学模型统计推断的影响

For multiple reasons -- such as avoiding overtraining from one data set or because of having received numerical estimates for some parameters in a model from an alternative source -- it is sometimes useful to divide a model's parameters into one group of primary parameters and one group of nuisance parameters. However, uncertainty in the values of nuisance parameters is an inevitable factor that impacts the model's reliability. This paper examines the issue of uncertainty…

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Efficient two-sample instrumental variable estimators with change points and near-weak identification

存在变点与近弱识别时的高效两样本工具变量估计

We consider estimation and inference in a linear model with endogenous regressors where the parameters of interest change across two samples. If the first-stage is common, we show how to use this information to obtain more efficient two-sample GMM estimators than the standard split-sample GMM, even in the presence of near-weak instruments. We also propose two tests to detect change points in the parameters of interest, depending on whether the first-stage is common or not.…

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A joint test of unconfoundedness and common trends

无混杂与共同趋势的联合检验

This paper introduces an overidentification test of two alternative assumptions to identify the average treatment effect on the treated in a two-period panel data setting: unconfoundedness and common trends. Under the unconfoundedness assumption, treatment assignment and post-treatment outcomes are independent, conditional on control variables and pre-treatment outcomes, which motivates including pre-treatment outcomes in the set of controls. Conversely, under the common…

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Statistical Inference for Bures-Wasserstein Flows

Bures–Wasserstein 协方差流的统计推断

We develop a statistical framework for conducting inference on collections of time-varying covariance operators (covariance flows) over a general, possibly infinite dimensional, Hilbert space. We model the intrinsically non-linear structure of covariances by means of the Bures-Wasserstein metric geometry. We make use of the Riemmanian-like structure induced by this metric to define a notion of mean and covariance of a random flow, and develop an associated Karhunen-Loève…

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Difference in Differences with Time-Varying Covariates

含时变协变量的双重差分

This paper considers identification and estimation of causal effect parameters from participating in a binary treatment in a difference in differences (DID) setup when the parallel trends assumption holds after conditioning on observed covariates. Relative to existing work in the econometrics literature, we consider the case where the value of covariates can change over time and, potentially, where participating in the treatment can affect the covariates themselves. We…

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Efficient estimation of longitudinal treatment effects using difference-in-differences and machine learning

利用双重差分与机器学习高效估计纵向处理效应

Difference-in-differences is based on a parallel trends assumption, which states that changes over time in average potential outcomes are independent of treatment assignment, possibly conditional on covariates. With time-varying treatments, parallel trends assumptions can identify many types of parameters, but most work has focused on group-time average treatment effects and similar parameters conditional on the treatment trajectory. This paper focuses instead on…

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Communication-Efficient Distributed Estimation and Inference for Cox's Model

Cox 模型的通信高效分布式估计与推断

Motivated by multi-center biomedical studies that cannot share individual data due to privacy and ownership concerns, we develop communication-efficient iterative distributed algorithms for estimation and inference in the high-dimensional sparse Cox proportional hazards model. We demonstrate that our estimator, even with a relatively small number of iterations, achieves the same convergence rate as the ideal full-sample estimator under very mild conditions. To construct…

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