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Transportability of Principal Causal Effects

主层因果效应的可迁移性

Recent research in causal inference has made important progress in addressing challenges to the external validity of trial findings. Such methods weight trial participant data to more closely resemble the distribution of effect-modifying covariates in a well-defined target population. In the presence of participant non-adherence to study medication, these methods effectively transport an intention-to-treat effect that averages over heterogeneous compliance behaviors. In this…

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Variable Selection in High Dimensional Linear Regressions with Parameter Instability

参数不稳定下的高维线性回归变量选择

This paper considers the problem of variable selection allowing for parameter instability. It distinguishes between signal and pseudo-signal variables that are correlated with the target variable, and noise variables that are not, and investigate the asymptotic properties of the One Covariate at a Time Multiple Testing (OCMT) method proposed by Chudik et al. (2018) under parameter insatiability. It is established that OCMT continues to asymptotically select an approximating…

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Hierarchical DCC-HEAVY Model for High-Dimensional Covariance Matrices

用于高维协方差矩阵的层级 DCC-HEAVY 模型

We introduce a HD DCC-HEAVY class of hierarchical-type factor models for high-dimensional covariance matrices, employing the realized measures built from higher-frequency data. The modelling approach features straightforward estimation and forecasting schemes, independent of the cross-sectional dimension of the assets under consideration, and accounts for sophisticated asymmetric dynamics in the covariances. Empirical analyses suggest that the HD DCC-HEAVY models have a…

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Discovery and inference of possibly bi-directional causal relationships with invalid instrumental variables

利用可能无效的工具变量发现双向因果关系并进行推断

Learning causal relationships between pairs of complex traits from observational studies is of great interest across various scientific domains. However, most existing methods assume the absence of unmeasured confounding and restrict causal relationships between two traits to be uni-directional, which may be violated in real-world systems. In this paper, we address the challenge of causal discovery and effect inference for two traits while accounting for unmeasured…

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ERM-Lasso classification algorithm for Multivariate Hawkes Processes paths

多元Hawkes过程路径的ERM-Lasso分类算法

We are interested in the problem of classifying Multivariate Hawkes Processes (MHP) paths coming from several classes. MHP form a versatile family of point processes that models interactions between connected individuals within a network. In this paper, the classes are discriminated by the exogenous intensity vector and the adjacency matrix, which encodes the strength of the interactions. The observed learning data consist of labeled repeated and independent paths on a fixed…

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A nonparametric test for rough volatility

粗糙波动率的非参数检验

We develop a nonparametric test for deciding whether volatility of an asset follows a standard semimartingale process, with paths of finite quadratic variation, or a rough process with paths of infinite quadratic variation. The test utilizes the fact that volatility is rough if and only if volatility increments are negatively autocorrelated at high frequencies. It is based on the sample autocovariance of increments of spot volatility estimates computed from high-frequency…

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Theory and inference for multivariate autoregressive binary models with an application to absence-presence data in ecology

多元自回归二元模型的理论与推断:生态出现数据应用

We introduce a general class of autoregressive models for studying the dynamic of multivariate binary time series with stationary exogenous covariates. Using a high-level set of assumptions, we show that existence of a stationary path for such models is almost automatic and does not require parameter restrictions when the noise term is not compactly supported. We then study in details statistical inference in a dynamic version of a multivariate probit type model, as a…

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Semiparametric Efficient Inference for the Probability of Necessary and Sufficient Causation

必要与充分因果概率的半参数有效推断

Causal attribution, which aims to explain why events or behaviors occur, is crucial in causal inference and enhances our understanding of cause-and-effect relationships in scientific research. The probabilities of necessary causation (PN) and sufficient causation (PS) are two of the most common quantities for attribution in causal inference. While many works have explored the identification or bounds of PN and PS, efficient estimation remains unaddressed. To fill this gap,…

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Low Volatility Stock Portfolio Through High Dimensional Bayesian Cointegration

通过高维贝叶斯协整构建低波动股票组合

We employ a Bayesian modelling technique for high dimensional cointegration estimation to construct low volatility portfolios from a large number of stocks. The proposed Bayesian framework effectively identifies sparse and important cointegration relationships amongst large baskets of stocks across various asset spaces, resulting in portfolios with reduced volatility. Such cointegration relationships persist well over the out-of-sample testing time, providing practical…

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Identification of Average Causal Effects in Confounded Additive Noise Models

存在混杂的加性噪声模型中平均因果效应的识别

Additive noise models (ANMs) are an important setting studied in causal inference. Most of the existing works on ANMs assume causal sufficiency, i.e., there are no unobserved confounders. This paper focuses on confounded ANMs, where a set of treatment variables and a target variable are affected by an unobserved confounder that follows a multivariate Gaussian distribution. We introduce a novel approach for estimating the average causal effects (ACEs) of any subset of the…

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Quantifying predictive uncertainty of aphasia severity in stroke patients with sparse heteroscedastic Bayesian high-dimensional regression

稀疏异方差贝叶斯高维回归量化卒中失语症严重程度的预测不确定性

Sparse linear regression methods for high-dimensional data commonly assume that residuals have constant variance, which can be violated in practice. For example, Aphasia Quotient (AQ) is a critical measure of language impairment and informs treatment decisions, but it is challenging to measure in stroke patients. It is of interest to use high-resolution T2 neuroimages of brain damage to predict AQ. However, sparse regression models show marked evidence of heteroscedastic…

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Regularizing stock return covariance matrices via multiple testing of correlations

通过相关系数多重检验正则化股票收益协方差矩阵

This paper develops a large-scale inference approach for the regularization of stock return covariance matrices. The framework allows for the presence of heavy tails and multivariate GARCH-type effects of unknown form among the stock returns. The approach involves simultaneous testing of all pairwise correlations, followed by setting non-statistically significant elements to zero. This adaptive thresholding is achieved through sign-based Monte Carlo resampling within…

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Inference procedures in sequential trial emulation with survival outcomes: comparing confidence intervals based on the sandwich variance estimator, bootstrap and jackknife

生存结局序贯试验模拟的推断:夹心方差、Bootstrap 与 Jackknife 比较

Sequential trial emulation (STE) is an approach to estimating causal treatment effects by emulating a sequence of target trials from observational data. In STE, inverse probability weighting is commonly utilised to address time-varying confounding and/or dependent censoring. Then structural models for potential outcomes are applied to the weighted data to estimate treatment effects. For inference, the simple sandwich variance estimator is popular but conservative, while…

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Maximum Entropy Estimation of Heterogeneous Causal Effects

异质性因果效应的最大熵估计

For the purpose of causal inference we employ a stochastic model of the data generating process, utilizing individual propensity probabilities for the treatment, and also individual and counterfactual prognosis probabilities for the outcome. We assume a generalized version of the stable unit treatment value assumption, but we do not assume any version of strongly ignorable treatment assignment. Instead of conducting a sensitivity analysis, we utilize the principle of maximum…

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An Introduction to Causal Discovery

因果发现导论

In social sciences and economics, causal inference traditionally focuses on assessing the impact of predefined treatments (or interventions) on predefined outcomes, such as the effect of education programs on earnings. Causal discovery, in contrast, aims to uncover causal relationships among multiple variables in a data-driven manner, by investigating statistical associations rather than relying on predefined causal structures. This approach, more common in computer science,…

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Information matrix test for normality of innovations in stationary time series models

平稳时间序列模型创新项正态性的信息矩阵检验

This study focuses on the problem of testing for normality of innovations in stationary time series models.To achieve this, we introduce an information matrix (IM) based test. While the IM test was originally developed to test for model misspecification, our study addresses that the test can also be used to test for the normality of innovations in various time series models. We provide sufficient conditions under which the limiting null distribution of the test statistics…

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Causal inference through multi-stage learning and doubly robust deep neural networks

多阶段学习与双重稳健深度神经网络的因果推断

Deep neural networks (DNNs) have demonstrated remarkable empirical performance in large-scale supervised learning problems, particularly in scenarios where both the sample size $n$ and the dimension of covariates $p$ are large. This study delves into the application of DNNs across a wide spectrum of intricate causal inference tasks, where direct estimation falls short and necessitates multi-stage learning. Examples include estimating the conditional average treatment effect…

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Robust CATE Estimation Using Novel Ensemble Methods

使用新型集成方法稳健估计条件平均处理效应

The estimation of Conditional Average Treatment Effects (CATE) is crucial for understanding the heterogeneity of treatment effects in clinical trials. We evaluate the performance of common methods, including causal forests and various meta-learners, across a diverse set of scenarios, revealing that each of the methods struggles in one or more of the tested scenarios. Given the inherent uncertainty of the data-generating process in real-life scenarios, the robustness of a…

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Adaptive Experiments Toward Learning Treatment Effect Heterogeneity

面向处理效应异质性学习的自适应实验

Understanding treatment effect heterogeneity has become an increasingly popular task in various fields, as it helps design personalized advertisements in e-commerce or targeted treatment in biomedical studies. However, most of the existing work in this research area focused on either analyzing observational data based on strong causal assumptions or conducting post hoc analyses of randomized controlled trial data, and there has been limited effort dedicated to the design of…

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Direct estimation and inference of higher-level correlations from lower-level measurements with applications in gene-pathway and proteomics studies

从低层级测量直接估计高层级相关性:基因通路与蛋白质组应用

This paper tackles the challenge of estimating correlations between higher-level biological variables (e.g., proteins and gene pathways) when only lower-level measurements are directly observed (e.g., peptides and individual genes). Existing methods typically aggregate lower-level data into higher-level variables and then estimate correlations based on the aggregated data. However, different data aggregation methods can yield varying correlation estimates as they target…

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Testing for sparse idiosyncratic components in factor-augmented regression models

检验因子增强回归中的稀疏特异成分

We propose a novel bootstrap test of a dense model, namely factor regression, against a sparse plus dense alternative augmenting model with sparse idiosyncratic components. The asymptotic properties of the test are established under time series dependence and polynomial tails. We outline a data-driven rule to select the tuning parameter and prove its theoretical validity. In simulation experiments, our procedure exhibits high power against sparse alternatives and low power…

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Two Stage Least Squares with Time-Varying Instruments: An Application to an Evaluation of Treatment Intensification for Type-2 Diabetes

使用时变工具变量的两阶段最小二乘:二型糖尿病治疗强化评估

As longitudinal data becomes more available in many settings, policy makers are increasingly interested in the effect of time-varying treatments (e.g. sustained treatment strategies). In settings such as this, the preferred analysis techniques are the g-methods, however these require the untestable assumption of no unmeasured confounding. Instrumental variable analyses can minimise bias through unmeasured confounding. Of these methods, the Two Stage Least Squares technique…

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Asymptotic locations of bounded and unbounded eigenvalues of sample correlation matrices of certain factor models -- application to a components retention rule

特定因子模型样本相关矩阵有界与发散特征值的渐近位置及成分保留规则

Let the dimension $N$ of data and the sample size $T$ tend to $\infty$ with $N/T \to c > 0$. The spectral properties of a sample correlation matrix $\mathbf{C}$ and a sample covariance matrix $\mathbf{S}$ are asymptotically equal whenever the population correlation matrix $\mathbf{R}$ is bounded (El Karoui 2009). We demonstrate this also for general linear models for unbounded $\mathbf{R}$, by examining the behavior of the singular values of multiplicatively perturbed…

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Covariate Assisted Entity Ranking with Sparse Intrinsic Scores

稀疏内在得分下的协变量辅助对象排序

This paper addresses the item ranking problem with associate covariates, focusing on scenarios where the preference scores can not be fully explained by covariates, and the remaining intrinsic scores, are sparse. Specifically, we extend the pioneering Bradley-Terry-Luce (BTL) model by incorporating covariate information and considering sparse individual intrinsic scores. Our work introduces novel model identification conditions and examines the regularized penalized Maximum…

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