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Causal Graph Aided Causal Discovery in an Observational Aneurysmal Subarachnoid Hemorrhage Study

因果图辅助的动脉瘤性蛛网膜下腔出血观察研究因果发现

Causal inference methods for observational data are increasingly recognized as a valuable complement to randomized clinical trials (RCTs). They can, under strong assumptions, emulate RCTs or help refine their focus. Our approach to causal inference uses causal directed acyclic graphs (DAGs). We are motivated by a concern that many observational studies in medicine begin without a clear definition of their objectives, without awareness of the scientific potential, and without…

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Identifying Total Causal Effects in Linear Models under Partial Homoscedasticity

部分同方差条件下线性模型总因果效应的识别

A fundamental challenge of scientific research is inferring causal relations based on observed data. One commonly used approach involves utilizing structural causal models that postulate noisy functional relations among interacting variables. A directed graph naturally represents these models and reflects the underlying causal structure. However, classical identifiability results suggest that, without conducting additional experiments, this causal graph can only be…

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Dynamical causality under invisible confounders

不可观测混杂因素下的动力系统因果关系

Causality inference is prone to spurious causal interactions, due to the substantial confounders in a complex system. While many existing methods based on the statistical methods or dynamical methods attempt to address misidentification challenges, there remains a notable lack of effective methods to infer causality, in particular in the presence of invisible/unobservable confounders. As a result, accurately inferring causation with invisible confounders remains a largely…

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Multiway empirical likelihood

多维交叉索引数据的经验似然

This paper develops a general methodology to conduct statistical inference for observations indexed by multiple sets of entities. We propose a novel multiway empirical likelihood statistic that converges to a chi-square distribution under the non-degenerate case, where corresponding Hoeffding type decomposition is dominated by linear terms. Our methodology is related to the notion of jackknife empirical likelihood but the leave-out pseudo values are constructed by leaving…

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Causal Discovery of Linear Non-Gaussian Causal Models with Unobserved Confounding

存在不可观测混杂的线性非高斯因果模型发现

We consider linear non-Gaussian structural equation models that involve latent confounding. In this setting, the causal structure is identifiable, but, in general, it is not possible to identify the specific causal effects. Instead, a finite number of different causal effects result in the same observational distribution. Most existing algorithms for identifying these causal effects use overcomplete independent component analysis (ICA), which often suffers from convergence…

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Difference-in-Differences for Health Policy and Practice: A Review of Modern Methods

健康政策与实践中的双重差分:现代方法综述

Difference-in-differences (DiD) is the most popular observational causal inference method in health policy, employed to evaluate the real-world impact of policies and programs. To estimate treatment effects, DiD relies on the "parallel trends assumption", that on average treatment and comparison groups would have had parallel trajectories in the absence of an intervention. Historically, DiD has been considered broadly applicable and straightforward to implement, but recent…

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Robust Estimation of Regression Models with Potentially Endogenous Outliers via a Modern Optimization Lens

从现代优化视角稳健估计含潜在内生异常值的回归模型

This paper addresses the robust estimation of linear regression models in the presence of potentially endogenous outliers. Through Monte Carlo simulations, we demonstrate that existing $L_1$-regularized estimation methods, including the Huber estimator and the least absolute deviation (LAD) estimator, exhibit significant bias when outliers are endogenous. Motivated by this finding, we investigate $L_0$-regularized estimation methods. We propose systematic heuristic…

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Parameter estimation for the generalized extreme value distribution: a method that combines bootstrapping and r largest order statistics

结合自助法与前 r 个最大次序统计量的广义极值分布参数估计

A critical problem in extreme value theory (EVT) is the estimation of parameters for the limit probability distributions. Block maxima (BM), an approach in EVT that seeks estimates of parameters of the generalized extreme value distribution (GEV), can be generalized to take into account not just the maximum realization from a given dataset, but the r largest order statistics for a given r. In this work we propose a parameter estimation method that combines the r largest…

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Predicting milk traits from spectral data using Bayesian probabilistic partial least squares regression

用贝叶斯概率偏最小二乘回归从光谱数据预测牛奶性状

High-dimensional spectral data -- routinely generated in dairy production -- are used to predict a range of traits in milk products. Partial least squares (PLS) regression is ubiquitously used for these prediction tasks. However, PLS regression is not typically viewed as arising from a probabilistic model, and parameter uncertainty is rarely quantified. Additionally, PLS regression does not easily lend itself to model-based modifications, coherent prediction intervals are…

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Theory of Evolutionary Spectra for Heteroskedasticity and Autocorrelation Robust Inference in Possibly Misspecified and Nonstationary Models

可能误设与非平稳模型中异方差和自相关稳健推断的演化谱理论

We develop a theory of evolutionary spectra for heteroskedasticity and autocorrelation robust (HAR) inference when the data may not satisfy second-order stationarity. Nonstationarity is a common feature of economic time series which may arise either from parameter variation or model misspecification. In such a context, the theories that support HAR inference are either not applicable or do not provide accurate approximations. HAR tests standardized by existing long-run…

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Change-Point Analysis of Time Series with Evolutionary Spectra

具有演化谱的时间序列变点分析

This paper develops change-point methods for the spectrum of a locally stationary time series. We focus on series with a bounded spectral density that change smoothly under the null hypothesis but exhibits change-points or becomes less smooth under the alternative. We address two local problems. The first is the detection of discontinuities (or breaks) in the spectrum at unknown dates and frequencies. The second involves abrupt yet continuous changes in the spectrum over a…

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The Fixed-b Limiting Distribution and the ERP of HAR Tests Under Nonstationarity

非平稳条件下 fixed-b 极限分布与 HAR 检验的拒绝概率误差

We show that the nonstandard limiting distribution of HAR test statistics under fixed-b asymptotics is not pivotal (even after studentization) when the data are nonstationarity. It takes the form of a complicated function of Gaussian processes and depends on the integrated local long-run variance and on on the second moments of the relevant series (e.g., of the regressors and errors for the case of the linear regression model). Hence, existing fixed-b inference methods based…

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Prewhitened Long-Run Variance Estimation Robust to Nonstationarity

对非平稳性稳健的预白化长期方差估计

We introduce a nonparametric nonlinear VAR prewhitened long-run variance (LRV) estimator for the construction of standard errors robust to autocorrelation and heteroskedasticity that can be used for hypothesis testing in a variety of contexts including the linear regression model. Existing methods either are theoretically valid only under stationarity and have poor finite-sample properties under nonstationarity (i.e., fixed-b methods), or are theoretically valid under the…

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Gaussian Approximation For Non-stationary Time Series with Optimal Rate and Explicit Construction

非平稳时间序列的高斯逼近:最优速率与显式构造

Statistical inference for time series such as curve estimation for time-varying models or testing for existence of change-point have garnered significant attention. However, these works are generally restricted to the assumption of independence and/or stationarity at its best. The main obstacle is that the existing Gaussian approximation results for non-stationary processes only provide an existential proof and thus they are difficult to apply. In this paper, we provide two…

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Hybrid Smoothing for Anomaly Detection in Time Series

用于时间序列异常检测的混合平滑方法

Many industrial and engineering processes monitored as times series have smooth trends that indicate normal behavior and occasionally anomalous patterns that can indicate a problem. This kind of behavior can be modeled by a smooth trend, such as a spline or Gaussian process, and a disruption based on a sparser representation. Our approach is to expand the process signal into two sets of basis functions: one set uses L2 penalties on the coefficients, and the other set uses L1…

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Spatial autoregressive model with measurement error in covariates

含协变量测量误差的空间自回归模型

The Spatial AutoRegressive model (SAR) is commonly used in studies involving spatial and network data to estimate the spatial or network peer influence and the effects of covariates on the response, taking into account the dependence among units. While the model can be efficiently estimated with a Quasi maximum likelihood approach (QMLE), the detrimental effect of covariate measurement error on the QMLE and how to remedy it is currently unknown. If covariates are measured…

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Advances in projection predictive inference

投影预测推断的进展

The concepts of Bayesian prediction, model comparison, and model selection have developed significantly over the last decade. As a result, the Bayesian community has witnessed a rapid growth in theoretical and applied contributions to building and selecting predictive models. Projection predictive inference in particular has shown promise to this end, finding application across a broad range of fields. It is less prone to over-fitting than naïve selection based purely on…

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PySDTest: a Python/Stata Package for Stochastic Dominance Tests

PySDTest:用于随机占优检验的 Python/Stata 软件包

We introduce PySDTest, a Python/Stata package for statistical tests of stochastic dominance. PySDTest implements various testing procedures such as Barrett and Donald (2003), Linton et al. (2005), Linton et al. (2010), and Donald and Hsu (2016), along with their extensions. Users can flexibly combine several resampling methods and test statistics, including the numerical delta method (Dümbgen, 1993; Hong and Li, 2018; Fang and Santos, 2019). The package allows for testing…

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Setting the duration of online A/B experiments

如何设定在线 A/B 实验的持续时间

In designing an online A/B experiment, it is crucial to select a sample size and duration that ensure the resulting confidence interval (CI) for the treatment effect is the right width to detect an effect of meaningful magnitude with sufficient statistical power without wasting resources. While the relationship between sample size and CI width is well understood, the effect of experiment duration on CI width remains less clear. This paper provides an analytical formula for…

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The projected dynamic linear model for time series on the sphere

球面时间序列的投影动态线性模型

Time series on the unit n-sphere arise in directional statistics, compositional data analysis, and many scientific fields. There are few models for such data, and the ones that exist suffer from several limitations: they are often computationally challenging to fit, many of them apply only to the circular case of n=2, and they are usually based on families of distributions that are not flexible enough to capture the complexities observed in real data. Furthermore, there is…

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Conformal Diffusion Models for Individual Treatment Effect Estimation and Inference

用于个体处理效应估计与推断的共形扩散模型

Estimating treatment effects from observational data is of central interest across numerous application domains. Individual treatment effect offers the most granular measure of treatment effect on an individual level, and is the most useful to facilitate personalized care. However, its estimation and inference remain underdeveloped due to several challenges. In this article, we propose a novel conformal diffusion model-based approach that addresses those intricate…

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Mixed moving average field guided learning for spatio-temporal data

混合移动平均场引导的时空数据学习

Influenced mixed moving average fields are a versatile modeling class for spatio-temporal data. However, their predictive distribution is not generally known. Under this modeling assumption, we define a novel spatio-temporal embedding and a theory-guided machine learning approach that employs a generalized Bayesian algorithm to make ensemble forecasts. We use Lipschitz predictors and determine fixed-time and any-time PAC Bayesian bounds in the batch learning setting.…

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Distilling interpretable causal trees from causal forests

从因果森林中蒸馏可解释的因果树

Machine learning methods for estimating treatment effect heterogeneity promise greater flexibility than existing methods that test a few pre-specified hypotheses. However, one problem these methods can have is that it can be challenging to extract insights from complicated machine learning models. A high-dimensional distribution of conditional average treatment effects may give accurate, individual-level estimates, but it can be hard to understand the underlying patterns;…

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More power to you: Using machine learning to augment human coding for more efficient inference in text-based randomized trials

用机器学习辅助人工编码,提高文本随机试验的推断效率

For randomized trials that use text as an outcome, traditional approaches for assessing treatment impact require that each document first be manually coded for constructs of interest by trained human raters. This process, the current standard, is both time-consuming and limiting: even the largest human coding efforts are typically constrained to measure only a small set of dimensions across a subsample of available texts. In this work, we present an inferential framework…

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