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Conditional nonparametric variable screening by neural factor regression

基于神经因子回归的条件非参数变量筛选

High-dimensional covariates often admit linear factor structure. To effectively screen correlated covariates in high-dimension, we propose a conditional variable screening test based on non-parametric regression using neural networks due to their representation power. We ask the question whether individual covariates have additional contributions given the latent factors or more generally a set of variables. Our test statistics are based on the estimated partial derivative…

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Gradient Wild Bootstrap for Instrumental Variable Quantile Regressions with Weak and Few Clusters

少数大聚类与弱识别下工具变量分位数回归的梯度野生自助法

We study the gradient wild bootstrap-based inference for instrumental variable quantile regressions in the framework of a small number of large clusters in which the number of clusters is viewed as fixed, and the number of observations for each cluster diverges to infinity. For the Wald inference, we show that our wild bootstrap Wald test, with or without studentization using the cluster-robust covariance estimator (CRVE), controls size asymptotically up to a small error as…

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High-Dimensional Covariate-Augmented Overdispersed Multi-Study Poisson Factor Model

高维协变量增强的过度离散多研究泊松因子模型

Factor analysis for high-dimensional data is a canonical problem in statistics and has a wide range of applications. However, there is currently no factor model tailored to effectively analyze high-dimensional count responses with corresponding covariates across multiple studies, such as the single-cell sequencing dataset from a case-control study. In this paper, we introduce factor models designed to jointly analyze multiple studies by extracting study-shared and specified…

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Valid Inference After Causal Discovery

因果发现之后的有效推断

Causal discovery and causal effect estimation are two fundamental tasks in causal inference. While many methods have been developed for each task individually, statistical challenges arise when applying these methods jointly: estimating causal effects after running causal discovery algorithms on the same data leads to "double dipping," invalidating the coverage guarantees of classical confidence intervals. To this end, we develop tools for valid post-causal-discovery…

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Spatial Knockoff Bayesian Variable Selection in Genome-Wide Association Studies

全基因组关联研究中的空间 Knockoff 贝叶斯变量选择

High-dimensional variable selection has emerged as one of the prevailing statistical challenges in the big data revolution. Many variable selection methods have been adapted for identifying single nucleotide polymorphisms (SNPs) linked to phenotypic variation in genome-wide association studies. We develop a Bayesian variable selection regression model for identifying SNPs linked to phenotypic variation. We modify our Bayesian variable selection regression models to control…

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Treatment bootstrapping: A new approach to quantify uncertainty of average treatment effect estimates

处理组自助法:量化匹配处理效应估计的不确定性

This paper proposes a new non-parametric bootstrap method to quantify the uncertainty of average treatment effect estimate for the treated from matching estimators. More specifically, it seeks to quantify the uncertainty associated with the average treatment effect estimate for the treated by bootstrapping the treatment group only and finding the counterpart control group by pair matching on estimated propensity score without replacement. We demonstrate the validity of this…

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Non-Plug-In Estimators Could Outperform Plug-In Estimators: a Cautionary Note and a Diagnosis

非代入估计量可能优于代入估计量:警示与诊断

Objectives: Highly flexible nonparametric estimators have gained popularity in causal inference and epidemiology. Popular examples of such estimators include targeted maximum likelihood estimators (TMLE) and double machine learning (DML). TMLE is often argued or suggested to be better than DML estimators and several other estimators in small to moderate samples -- even if they share the same large-sample properties -- because TMLE is a plug-in estimator and respects the…

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Measuring Diagnostic Test Performance Using Imperfect Reference Tests: A Partial Identification Approach

不完美参照检测下诊断性能的部分识别

Diagnostic tests are almost never perfect. Studies quantifying their performance use knowledge of the true health status, measured with a reference diagnostic test. Researchers commonly assume that the reference test is perfect, which is often not the case in practice. When the assumption fails, conventional studies identify "apparent" performance or performance with respect to the reference, but not true performance. This paper provides the smallest possible bounds on the…

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Deep Learning for the Estimation of Heterogeneous Parameters in Discrete Choice Models

离散选择模型异质参数估计中的深度学习

This paper studies the finite sample performance of the flexible estimation approach of Farrell, Liang, and Misra (2021a), who propose to use deep learning for the estimation of heterogeneous parameters in economic models, in the context of discrete choice models. The approach combines the structure imposed by economic models with the flexibility of deep learning, which assures the interpretebility of results on the one hand, and allows estimating flexible functional forms…

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An exhaustive selection of sufficient adjustment sets for causal inference

因果推断中充分调整集的穷尽选择

A subvector of predictor that satisfies the ignorability assumption, whose index set is called a sufficient adjustment set, is crucial for conducting reliable causal inference based on observational data. In this paper, we propose a general family of methods to detect all such sets for the first time in the literature, with no parametric assumptions on the outcome models and with flexible parametric and semiparametric assumptions on the predictor within the treatment groups;…

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Method of Moments Estimation for Affine Stochastic Volatility Models

仿射随机波动率模型的矩估计

We develop moment estimators for the parameters of affine stochastic volatility models. We first address the challenge of calculating moments for the models by introducing a recursive equation for deriving closed-form expressions for moments of any order. Consequently, we propose our moment estimators. We then establish a central limit theorem for our estimators and derive the explicit formulas for the asymptotic covariance matrix. Finally, we provide numerical results to…

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On Doubly Robust Estimation with Nonignorable Missing Data Using Instrumental Variables

利用工具变量处理不可忽略缺失的双重稳健估计

Suppose we are interested in the mean of an outcome that is subject to nonignorable nonresponse. This paper develops new semiparametric estimation methods with instrumental variables which affect nonresponse, but not the outcome. The proposed estimators remain consistent and asymptotically normal even under partial model misspecifications for two variation independent nuisance components. We evaluate the performance of the proposed estimators via a simulation study, and…

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Causal Inference on Process Graphs, Part I: The Structural Equation Process Representation

过程图上的因果推断(一):结构方程过程表示

When dealing with time series data, causal inference methods often employ structural vector autoregressive (SVAR) processes to model time-evolving random systems. In this work, we rephrase recursive SVAR processes with possible latent component processes as a linear Structural Causal Model (SCM) of stochastic processes on a simple causal graph, the process graph, that models every process as a single node. Using this reformulation, we generalise Wright's well-known path-rule…

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Causal Inference on Process Graphs, Part II: Causal Structure and Effect Identification

过程图上的因果推断(二):因果结构与效应识别

A structural vector autoregressive (SVAR) process is a linear causal model for variables that evolve over a discrete set of time points and between which there may be lagged and instantaneous effects. The qualitative causal structure of an SVAR process can be represented by its finite and directed process graph, in which a directed link connects two processes whenever there is a lagged or instantaneous effect between them. At the process graph level, the causal structure of…

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Estimating Causal Effects for Binary Outcomes Using Per-Decision Inverse Probability Weighting

用逐决策逆概率加权估计二元结局因果效应

Micro-randomized trials are commonly conducted for optimizing mobile health interventions such as push notifications for behavior change. In analyzing such trials, causal excursion effects are often of primary interest, and their estimation typically involves inverse probability weighting (IPW). However, in a micro-randomized trial, additional treatments can often occur during the time window over which an outcome is defined, and this can greatly inflate the variance of the…

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Anytime-valid off-policy inference for contextual bandits

情境赌博机的任意时刻有效离策略推断

Contextual bandit algorithms are ubiquitous tools for active sequential experimentation in healthcare and the tech industry. They involve online learning algorithms that adaptively learn policies over time to map observed contexts $X_t$ to actions $A_t$ in an attempt to maximize stochastic rewards $R_t$. This adaptivity raises interesting but hard statistical inference questions, especially counterfactual ones: for example, it is often of interest to estimate the properties…

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Classification of High-dimensional Time Series in Spectral Domain using Explainable Features

利用可解释频域特征分类高维时间序列

Interpretable classification of time series presents significant challenges in high dimensions. Traditional feature selection methods in the frequency domain often assume sparsity in spectral density matrices (SDMs) or their inverses, which can be restrictive for real-world applications. In this article, we propose a model-based approach for classifying high-dimensional stationary time series by assuming sparsity in the difference between inverse SDMs. Our approach…

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On the effect of noise on fitting linear regression models

噪声对线性回归模型拟合的影响

In this study, we explore the effects of including noise predictors and noise observations when fitting linear regression models. We present empirical and theoretical results that show that double descent occurs in both cases, albeit with contradictory implications: the implication for noise predictors is that complex models are often better than simple ones, while the implication for noise observations is that simple models are often better than complex ones. We resolve…

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Inverting estimating equations for causal inference on quantiles

通过反演估计方程进行分位数因果推断

The causal inference literature frequently focuses on estimating the mean of the potential outcome, whereas quantiles of the potential outcome may carry important additional information. We propose a unified approach, based on the inverse estimating equations, to generalize a class of causal inference solutions from estimating the mean of the potential outcome to its quantiles. We assume that a moment function is available to identify the mean of the threshold-transformed…

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A General Framework for Treatment Effect Estimation in Semi-Supervised and High Dimensional Settings

半监督与高维环境下处理效应估计的一般框架

In this article, we aim to provide a general and complete understanding of semi-supervised (SS) causal inference for treatment effects. Specifically, we consider two such estimands: (a) the average treatment effect and (b) the quantile treatment effect, as prototype cases, in an SS setting, characterized by two available data sets: (i) a labeled data set of size $n$, providing observations for a response and a set of high dimensional covariates, as well as a binary treatment…

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Estimation of the Number Needed to Treat, the Number Needed to be Exposed, and the Exposure Impact Number with Instrumental Variables

使用工具变量估计需治疗人数、需暴露人数与暴露影响人数

The Number needed to treat (NNT) is an efficacy index defined as the average number of patients needed to treat to attain one additional treatment benefit. In observational studies, specifically in epidemiology, the adequacy of the populationwise NNT is questionable since the exposed group characteristics may substantially differ from the unexposed. To address this issue, groupwise efficacy indices were defined: the Exposure Impact Number (EIN) for the exposed group and the…

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Inference for Local Projections

局部投影的推断

Inference for impulse responses estimated with local projections presents interesting challenges and opportunities. Analysts typically want to assess the precision of individual estimates, explore the dynamic evolution of the response over particular regions, and generally determine whether the impulse generates a response that is any different from the null of no effect. Each of these goals requires a different approach to inference. In this article, we provide an overview…

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Panel Data Unit Root testing: Overview

面板数据单位根检验综述

This review discusses methods of testing for a panel unit root. Modern approaches to testing in cross-sectionally correlated panels are discussed, preceding the analysis with an analysis of independent panels. In addition, methods for testing in the case of non-linearity in the data (for example, in the case of structural breaks) are presented, as well as methods for testing in short panels, when the time dimension is small and finite. In conclusion, links to existing…

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Post-selection inference for high-dimensional mediation analysis with survival outcomes

生存结局高维中介分析的选择后推断

It is of substantial scientific interest to detect mediators that lie in the causal pathway from an exposure to a survival outcome. However, with high-dimensional mediators, as often encountered in modern genomic data settings, there is a lack of powerful methods that can provide valid post-selection inference for the identified marginal mediation effect. To resolve this challenge, we develop a post-selection inference procedure for the maximally selected natural indirect…

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