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Transfer Learning Meets Functional Linear Regression: No Negative Transfer under Posterior Drift

迁移学习遇上函数线性回归:后验漂移下无负迁移

Posterior drift refers to changes in the relationship between responses and covariates while the distributions of the covariates remain unchanged. In this work, we explore functional linear regression under posterior drift with transfer learning. Specifically, we investigate when and how auxiliary data can be leveraged to improve the estimation accuracy of the slope function in the target model when posterior drift occurs. We employ the approximated least square method…

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Time-Varying Functional Cox Model

时变函数型 Cox 模型

We propose two novel approaches for estimating time-varying effects of functional predictors within a linear functional Cox model framework. This model allows for time-varying associations of a functional predictor observed at baseline, estimated using penalized regression splines for smoothness across the functional domain and event time. The first approach, suitable for small-to-medium datasets, uses the Cox-Poisson likelihood connection for valid estimation and inference.…

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Model-free Approach to Evaluate a Censored Intermediate Outcome as a Surrogate for Overall Survival

以无模型方法评估删失中间结局对总生存期的替代作用

Clinical trials or studies oftentimes require long-term and/or costly follow-up of participants to evaluate a novel treatment/drug/vaccine. There has been increasing interest in the past few decades in using short-term surrogate outcomes as a replacement of the primary outcome i.e., in using the surrogate outcome, which can potentially be observed sooner, to make inference about the treatment effect on the long-term primary outcome. Very few of the available statistical…

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Optimal Exact Recovery in Semi-Supervised Learning: A Study of Spectral Methods and Graph Convolutional Networks

半监督学习中的最优精确恢复:谱方法与图卷积网络研究

We delve into the challenge of semi-supervised node classification on the Contextual Stochastic Block Model (CSBM) dataset. Here, nodes from the two-cluster Stochastic Block Model (SBM) are coupled with feature vectors, which are derived from a Gaussian Mixture Model (GMM) that corresponds to their respective node labels. With only a subset of the CSBM node labels accessible for training, our primary objective becomes the accurate classification of the remaining nodes.…

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First-order integer-valued autoregressive processes with Generalized Katz innovations

具有广义Katz创新项的一阶整数值自回归过程

A new integer--valued autoregressive process (INAR) with Generalised Lagrangian Katz (GLK) innovations is defined. This process family provides a flexible modelling framework for count data, allowing for under and over--dispersion, asymmetry, and excess of kurtosis and includes standard INAR models such as Generalized Poisson and Negative Binomial as special cases. We show that the GLK--INAR process is discrete semi--self--decomposable, infinite divisible, stable by…

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The Estimand Framework and Causal Inference: Complementary not Competing Paradigms

目标估计量框架与因果推断:相互补充的范式

The creation of the ICH E9 (R1) estimands framework has led to more precise specification of the treatment effects of interest in the design and statistical analysis of clinical trials. However, it is unclear how the new framework relates to causal inference, as both approaches appear to define what is being estimated and have a quantity labelled an estimand. Using illustrative examples, we show that both approaches can be used to define a population-based summary of an…

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FDR Control for Online Anomaly Detection

在线异常检测中的错误发现率控制

A new online multiple testing procedure is described in the context of anomaly detection, which controls the False Discovery Rate (FDR). An accurate anomaly detector must control the false positive rate at a prescribed level while keeping the false negative rate as low as possible. However in the online context, such a constraint remains highly challenging due to the usual lack of FDR control: the online framework makes it impossible to use classical multiple testing…

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Variable importance measures for heterogeneous treatment effects with survival outcome

生存结局下异质性处理效应的变量重要性度量

Treatment effect heterogeneity plays an important role in many areas of causal inference and within recent years, estimation of the conditional average treatment effect (CATE) has received much attention in the statistical community. While accurate estimation of the CATE-function through flexible machine learning procedures provides a tool for prediction of the individual treatment effect, it does not provide further insight into the driving features of potential treatment…

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Functional conditional volatility modeling with missing data: inference and application to energy commodities

缺失数据下的函数型条件波动率建模及能源商品应用

This paper explores the nonparametric estimation of the volatility component in a heteroscedastic scalar-on-function regression model, where the underlying discrete-time process is ergodic and subject to a missing-at-random mechanism. We first propose a simplified estimator for the regression and volatility operators, constructed solely from the observed data. The asymptotic properties of these estimators, including the almost sure uniform consistency rate and asymptotic…

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Autoregressive hidden Markov models for high-resolution animal movement data

面向高分辨率动物移动数据的自回归隐马尔可夫模型

New types of high-resolution animal movement data allow for increasingly comprehensive biological inference, but method development to meet the statistical challenges associated with such data is lagging behind. In this contribution, we extend the commonly applied hidden Markov models for step lengths and turning angles to address the specific requirements posed by high-resolution movement data, in particular the very strong within-state correlation induced by the momentum…

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A clarification on the links between potential outcomes and do-interventions

潜在结果与do干预之间关系的澄清

Most of the scientific literature on causal modeling considers the structural framework of Pearl and the potential-outcome framework of Rubin to be formally equivalent, and therefore interchangeably uses do-interventions and the potential-outcome subscript notation to write counterfactual outcomes. In this paper, we agnostically superimpose the two causal models to specify under which mathematical conditions structural counterfactual outcomes and potential outcomes need to,…

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Estimating Conditional Average Treatment Effects with Heteroscedasticity by Model Averaging and Matching

结合模型平均与匹配估计异方差下的条件平均处理效应

We propose a model averaging approach, combined with a partition and matching method to estimate the conditional average treatment effects under heteroskedastic error settings. The proposed approach has asymptotic optimality and consistency of weights and estimator. Numerical studies show that our method has good finite-sample performances.

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Moderating the Mediation Bootstrap for Causal Inference

因果中介分析中Bootstrap推断的校准问题

Mediation analysis is a form of causal inference that investigates indirect effects and causal mechanisms. Confidence intervals for indirect effects play a central role in conducting inference. The problem is non-standard leading to coverage rates that deviate considerably from their nominal level. The default inference method in the mediation model is the paired bootstrap, which resamples directly from the observed data. However, a residual bootstrap that explicitly…

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ABC3: Active Bayesian Causal Inference with Cohn Criteria in Randomized Experiments

ABC3:基于Cohn准则的随机实验贝叶斯主动因果推断

In causal inference, randomized experiment is a de facto method to overcome various theoretical issues in observational study. However, the experimental design requires expensive costs, so an efficient experimental design is necessary. We propose ABC3, a Bayesian active learning policy for causal inference. We show a policy minimizing an estimation error on conditional average treatment effect is equivalent to minimizing an integrated posterior variance, similar to Cohn…

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Nonparametric Causal Decomposition of Group Disparities

群体差距的非参数因果分解

We introduce a new nonparametric causal decomposition approach that identifies the mechanisms by which a treatment variable contributes to a group-based outcome disparity. Our approach distinguishes three mechanisms: group differences in 1) treatment prevalence, 2) average treatment effects, and 3) selection into treatment based on individual-level treatment effects. Our approach reformulates classic Kitagawa-Blinder-Oaxaca decompositions in causal and nonparametric terms,…

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An Identification and Dimensionality Robust Test for Instrumental Variables Models

工具变量模型中对识别与维度稳健的检验

Using modifications of Lindeberg's interpolation technique, I propose a new identification-robust test for the structural parameter in a heteroskedastic instrumental variables model. While my analysis allows the number of instruments to be much larger than the sample size, it does not require many instruments, making my test applicable in settings that have not been well studied. Instead, the proposed test statistic has a limiting chi-squared distribution so long as an…

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Doubly regularized generalized linear models for spatial observations with high-dimensional covariates

面向高维协变量空间观测的双重正则化广义线性模型

A discrete spatial lattice can be cast as a network structure over which spatially-correlated outcomes are observed. A second network structure may also capture similarities among measured features, when such information is available. Incorporating the network structures when analyzing such doubly-structured data can improve predictive power, and lead to better identification of important features in the data-generating process. Motivated by applications in spatial disease…

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Bayesian inference on Cox regression models using catalytic prior distributions

基于催化先验分布的Cox回归模型贝叶斯推断

The Cox proportional hazards model (Cox model) is a popular model for survival data analysis. When the sample size is small relative to the dimension of the model, the standard maximum partial likelihood inference is often problematic. In this work, we propose the Cox catalytic prior distributions for Bayesian inference on Cox models, which is an extension of a general class of prior distributions originally designed for stabilizing complex parametric models. The Cox…

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Identification and estimation of causal effects using non-concurrent controls in platform trials

平台试验中利用非同期对照识别与估计因果效应

Platform trials are multi-arm designs that simultaneously evaluate multiple treatments for a single disease within the same overall trial structure. Unlike traditional randomized controlled trials, they allow treatment arms to enter and exit the trial at distinct times while maintaining a control arm throughout. This control arm comprises both concurrent controls, where participants are randomized concurrently to either the treatment or control arm, and non-concurrent…

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Model Selection for Causal Modeling in Missing Exposure Problems

暴露缺失情形下因果建模的模型选择

In causal inference, properly selecting the propensity score (PS) model is an important topic and has been widely investigated in observational studies. There is also a large literature focusing on the missing data problem. However, there are very few studies investigating the model selection issue for causal inference when the exposure is missing at random (MAR). In this paper, we discuss how to select both imputation and PS models, which can result in the smallest root…

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Sequential Change Point Detection in High-dimensional Vector Auto-regressive Models

高维向量自回归模型中的序贯变点检测

Sequential (online) change-point detection involves continuously monitoring time-series data and triggering an alarm when shifts in the data distribution are detected. We propose an algorithm for real-time identification of alterations in the transition matrices of high-dimensional vector autoregressive models. The algorithm estimates transition matrices and error term variances using regularization techniques applied to training data, then computes a specific test statistic…

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A class of nonparametric methods for evaluating the effect of continuous treatments on survival outcomes

评估连续处理对生存结局影响的一类非参数方法

In randomized trials and observational studies, it is often necessary to evaluate the extent to which an intervention affects a time-to-event outcome, which is only partially observed due to right censoring. For instance, in infectious disease studies, it is frequently of interest to characterize the relationship between risk of acquisition of infection with a pathogen and a biomarker previously measuring for an immune response against that pathogen induced by prior…

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Tucker tensor factor models: matricization and mode-wise PCA estimation

Tucker 张量因子模型:矩阵化与逐模态主成分估计

High-dimensional, higher-order tensor data are gaining prominence in a variety of fields, including but not limited to computer vision and network analysis. Tensor factor models, induced from noisy versions of tensor decompositions or factorizations, are natural potent instruments to study a collection of tensor-variate objects that may be dependent or independent. However, it is still in the early stage of developing statistical inferential theories for the estimation of…

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Doubly-robust inference and optimality in structure-agnostic models with smoothness

带平滑性约束的结构无关模型中的双重稳健推断与最优性

We study the problem of constructing an estimator of the average treatment effect (ATE) with observational data. The celebrated doubly-robust, augmented-IPW (AIPW) estimator generally requires consistent estimation of both nuisance functions for standard root-n inference, and moreover that the product of the errors of the nuisances should shrink at a rate faster than $n^{-1/2}$. A recent strand of research has aimed to understand the extent to which the AIPW estimator can be…

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