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A Shrinkage Likelihood Ratio Test for High-Dimensional Subgroup Analysis with a Logistic-Normal Mixture Model

逻辑斯蒂—正态混合模型下高维亚组分析的收缩似然比检验

In subgroup analysis, testing the existence of a subgroup with a differential treatment effect serves as protection against spurious subgroup discovery. Despite its importance, this hypothesis testing possesses a complicated nature: parameter characterizing subgroup classification is not identified under the null hypothesis of no subgroup. Due to this irregularity, the existing methods have the following two limitations. First, the asymptotic null distribution of test…

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An extensive simulation study evaluating the interaction of resampling techniques across multiple causal discovery contexts

不同因果发现情境下重抽样技术交互作用的大规模模拟研究

Despite the accelerating presence of exploratory causal analysis in modern science and medicine, the available non-experimental methods for validating causal models are not well characterized. One of the most popular methods is to evaluate the stability of model features after resampling the data, similar to resampling methods for estimating confidence intervals in statistics. Many aspects of this approach have received little to no attention, however, such as whether the…

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Dynamic Investment Strategies Through Market Classification and Volatility: A Machine Learning Approach

基于市场分类与波动率的动态投资策略:机器学习方法

This study introduces a dynamic investment framework to enhance portfolio management in volatile markets, offering clear advantages over traditional static strategies. Evaluates four conventional approaches : equal weighted, minimum variance, maximum diversification, and equal risk contribution under dynamic conditions. Using K means clustering, the market is segmented into ten volatility-based states, with transitions forecasted by a Bayesian Markov switching model…

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Spatial Data Analysis

空间数据分析

This handbook chapter provides an essential introduction to the field of spatial econometrics, offering a comprehensive overview of techniques and methodologies for analysing spatial data in the social sciences. Spatial econometrics addresses the unique challenges posed by spatially dependent observations, where spatial relationships among data points can be of substantive interest or can significantly impact statistical analyses. The chapter begins by exploring the…

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A Note on Local Linear Regression for Time Series in Banach Spaces

Banach 空间值时间序列的局部线性回归札记

This work extends local linear regression to Banach space-valued time series for estimating smoothly varying means and their derivatives in non-stationary data. The asymptotic properties of both the standard and bias-reduced Jackknife estimators are analyzed under mild moment conditions, establishing their convergence rates. Simulation studies assess the finite sample performance of these estimators and compare them with the Nadaraya-Watson estimator. Additionally, the…

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Linear programming approach to partially identified econometric models

部分识别计量模型的线性规划方法

Sharp bounds on partially identified parameters are often given by the values of linear programs (LPs). This paper introduces a novel estimator of the LP value. Unlike existing procedures, our estimator is root-n-consistent, pointwise in the probability measure, whenever the population LP is feasible and finite. Our estimator is valid under point-identification, over-identifying constraints, and solution multiplicity. Turning to uniformity properties, we prove that the LP…

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Information-theoretic limits and approximate message-passing for high-dimensional time series

高维时间序列的信息论极限与近似消息传递

High-dimensional time series appear in many scientific setups, demanding a nuanced approach to model and analyze the underlying dependence structure. Theoretical advancements so far often rely on stringent assumptions regarding the sparsity of the underlying signal. In non-sparse regimes, analyses have primarily focused on linear regression models with the design matrix having independent rows. In this paper, we expand the scope by investigating a high-dimensional time…

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Uniform Convergence Rate of the Nonparametric Estimator for Integrated Diffusion Processes

积分扩散过程非参数估计量的一致收敛速度

The nonparametric estimation of integrated diffusion processes has been extensively studied, with most existing research focusing on pointwise convergence. This paper is the first to establish uniform convergence rates for the Nadaraya-Watson estimators of their coefficients. We derive these rates over unbounded support under the assumptions of a vanishing observation interval and a long time horizon. Our findings serve as essential tools for specification testing and…

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The Hardness of Validating Observational Studies with Experimental Data

使用实验数据验证观察研究的理论困难

Observational data is often readily available in large quantities, but can lead to biased causal effect estimates due to the presence of unobserved confounding. Recent works attempt to remove this bias by supplementing observational data with experimental data, which, when available, is typically on a smaller scale due to the time and cost involved in running a randomised controlled trial. In this work, we prove a theorem that places fundamental limits on this ``best of both…

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A Unified Framework for Semiparametrically Efficient Semi-Supervised Learning

半参数有效半监督学习的统一框架

We consider statistical inference under a semi-supervised setting where we have access to both a labeled dataset consisting of pairs $\{X_i, Y_i \}_{i=1}^n$ and an unlabeled dataset $\{ X_i \}_{i=n+1}^{n+N}$. We ask the question: under what circumstances, and by how much, can incorporating the unlabeled dataset improve upon inference using the labeled data? To answer this question, we investigate semi-supervised learning through the lens of semiparametric efficiency theory.…

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Hazard Rate for Associated Data in Deconvolution Problems: Asymptotic Normality

反卷积问题中关联数据的风险率:渐近正态性

In reliability theory and survival analysis, observed data are often weakly dependent and subject to additive measurement errors. Such contamination arises when the underlying data are neither independent nor strongly mixed but instead exhibit association. This paper focuses on estimating the hazard rate by deconvolving the density function and constructing an estimator of the distribution function. We assume that the data originate from a strictly stationary sequence…

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Counterfactual Generative Modeling with Variational Causal Inference

基于变分因果推断的反事实生成建模

Estimating an individual's counterfactual outcomes under interventions is a challenging task for traditional causal inference and supervised learning approaches when the outcome is high-dimensional (e.g. gene expressions, facial images) and covariates are relatively limited. In this case, to predict one's outcomes under counterfactual treatments, it is crucial to leverage individual information contained in the observed outcome in addition to the covariates. Prior works…

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Robust tests for log-logistic models based on minimum density power divergence estimators

基于最小密度幂散度估计的对数逻辑斯蒂模型稳健检验

The log-logistic distribution is a versatile parametric family widely used across various applied fields, including survival analysis, reliability engineering, and econometrics. When estimating parameters of the log-logistic distribution, hypothesis testing is necessary to verify assumptions about these parameters. The Wald test and Rao test provide formal methods for testing hypotheses about these parameters. However, these test statistics are not robust, and their…

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The covariance of causal effect estimators for binary v-structures

二元 V 形结构中因果效应估计量的协方差

Previously [Journal of Causal Inference, 10, 90-105 (2022)], we computed the variance of two estimators of causal effects for a v-structure of binary variables. Here we show that a linear combination of these estimators has lower variance than either. Furthermore, we show that this holds also when the treatment variable is block randomised with a predefined number receiving treatment, with analogous results to when it is sampled randomly.

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A flexible control function approach for survival data subject to different types of censoring

适用于多种删失机制的生存数据灵活控制函数方法

This paper addresses the problem of identifying and estimating the causal effect of a treatment in the presence of unmeasured confounding and various types of right-censoring. Examples of these censoring mechanisms are administrative censoring, competing risks and dependent censoring (e.g. loss to follow-up). Different parametric transformations are applied to each event time, resulting in a regression model with a more additive structure and error terms that are…

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A Note on the Asymptotic Properties of the GLS Estimator in Multivariate Regression with Heteroskedastic and Autocorrelated Errors

异方差与自相关误差下多元回归 GLS 估计量的渐近性质札记

We study the asymptotic properties of the GLS estimator in multivariate regression with heteroskedastic and autocorrelated errors. We derive Wald statistics for linear restrictions and assess their performance. The statistics remains robust to heteroskedasticity and autocorrelation.

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Nonparametric estimation of conditional densities by generalized random forests

利用广义随机森林非参数估计条件密度

Considering a continuous random variable Y together with a continuous random vector X, I propose a nonparametric estimator f^(.|x) for the conditional density of Y given X=x. This estimator takes the form of an exponential series whose coefficients Tx = (Tx1,...,TxJ) are the solution of a system of nonlinear equations that depends on an estimator of the conditional expectation E[p(Y)|X=x], where p is a J-dimensional vector of basis functions. The distinguishing feature of…

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Debiased Nonparametric Regression for Statistical Inference and Distributionally Robustness

用于统计推断与分布稳健性的去偏非参数回归

This study proposes a debiasing method for smooth nonparametric estimators. While machine learning techniques such as random forests and neural networks have demonstrated strong predictive performance, their theoretical properties remain relatively underexplored. In particular, many modern algorithms lack guarantees of pointwise and uniform risk convergence, as well as asymptotic normality. These properties are essential for statistical inference and robust estimation and…

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fkbma: An R Package for Detecting Tailoring Variables with Free-Knot B-Splines and Bayesian Model Averaging

fkbma:以自由节点 B 样条和贝叶斯模型平均识别治疗定制变量的 R 包

Precision medicine aims to optimize treatment by identifying patient subgroups most likely to benefit from specific interventions. To support this goal, we introduce fkbma, an R package that implements a Bayesian model averaging approach with free-knot B-splines for identifying tailoring variables. The package employs a reversible jump Markov chain Monte Carlo algorithm to flexibly model treatment effect heterogeneity while accounting for uncertainty in both variable…

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A robust score test in g-computation for covariate adjustment in randomized clinical trials leveraging different variance estimators via influence functions

随机临床试验协变量调整中基于影响函数方差的稳健 g 计算得分检验

G-computation has become a widely used robust method for estimating unconditional (marginal) treatment effects with covariate adjustment in the analysis of randomized clinical trials. Statistical inference in this context typically relies on the Wald test or Wald interval, which can be easily implemented using a consistent variance estimator. However, existing literature suggests that when sample sizes are small or when parameters of interest are near boundary values,…

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H-AddiVortes: Heteroscedastic (Bayesian) Additive Voronoi Tessellations

异方差贝叶斯加性 Voronoi 镶嵌模型

This paper introduces the Heteroscedastic AddiVortes model, a Bayesian non-parametric regression framework that simultaneously models the conditional mean and variance of a response variable using adaptive Voronoi tessellations. By employing a sum-of-tessellations approach for the mean and a product-of-tessellations approach for the variance, the model provides a flexible and interpretable means to capture complex, predictor-dependent relationships and heteroscedastic…

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A Doubly Robust Instrumental Variable Approach for Estimating Average Treatment Effects in Time-to-Event Data with Unmeasured Confounding: Application to Real-World Data on ICU Patients with Septic Shock

未测混杂下生存结局平均处理效应的双重稳健工具变量方法

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE) in time-to-event data. In real-world data, IV methods are widely used for estimating causal treatment effects in the presence of unmeasured confounding, but existing approaches for time-to-event outcomes are often constrained by strong…

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BudgetIV: Optimal Partial Identification of Causal Effects with Mostly Invalid Instruments

BudgetIV:多数工具变量无效时因果效应的最优部分识别

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the outcome. We present a framework for relaxing either or both of these strong assumptions with tuneable and interpretable budget constraints. Our algorithm returns a feasible set of causal effects that can be identified exactly given relevant…

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Identification and estimation of structural vector autoregressive models via LU decomposition

利用 LU 分解识别与估计结构向量自回归模型

Structural vector autoregressive (SVAR) models are widely used to analyze the simultaneous relationships between multiple time-dependent data. Various statistical inference methods have been studied to overcome the identification problems of SVAR models. However, most of these methods impose strong assumptions for innovation processes such as the uncorrelation of components. In this study, we relax the assumptions for innovation processes and propose an identification method…

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