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Adaptive adequacy testing of high-dimensional factor-augmented regression model

高维因子增广回归模型的自适应充分性检验

In this paper, we investigate the adequacy testing problem of high-dimensional factor-augmented regression model. Existing test procedures perform not well under dense alternatives. To address this critical issue, we introduce a novel quadratic-type test statistic which can efficiently detect dense alternative hypotheses. We further propose an adaptive test procedure to remain powerful under both sparse and dense alternative hypotheses. Theoretically, under the null…

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Multiple Testing under High-dimensional Dynamic Factor Model

高维动态因子模型下的多重检验

Large-scale multiple testing under static factor models is widely used to detect sparse signals in high-dimensional data. However, static factor models are arguably too stringent because they ignore serial correlation, which seriously distorts error rate control in large-scale inference. In this manuscript, we propose a new multiple testing procedure under dynamic factor models that is robust to nonlinear serial dependence. The idea is to integrate a new sample-splitting…

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Estimation of the complier causal hazard ratio under dependent censoring

依赖删失下服从者因果风险比的估计

In this work, we are interested in studying the causal effect of an endogenous binary treatment on a dependently censored duration outcome. By dependent censoring, it is meant that the duration time ($T$) and right censoring time ($C$) are not statistically independent of each other, even after conditioning on the measured covariates. The endogeneity issue is handled by making use of a binary instrumental variable for the treatment. To deal with the dependent censoring…

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Non-parametric Quantile Regression and Uniform Inference with Unknown Error Distribution

未知测量误差分布下的非参数分位数回归与一致推断

This paper studies the non-parametric estimation and uniform inference for the conditional quantile regression function (CQRF) with covariates exposed to measurement errors. We consider the case that the distribution of the measurement error is unknown and allowed to be either ordinary or super smooth. We estimate the density of the measurement error by the repeated measurements and propose the deconvolution kernel estimator for the CQRF. We derive the uniform Bahadur…

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A Causal Inference Framework for Data Rich Environments

数据丰富环境下的因果推断框架

We propose a formal model for counterfactual estimation with unobserved confounding in "data-rich" settings, i.e., where there are a large number of units and a large number of measurements per unit. Our model provides a bridge between the structural causal model view of causal inference common in the graphical models literature with that of the latent factor model view common in the potential outcomes literature. We show how classic models for potential outcomes and…

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Assessing mediation in cross-sectional stepped wedge cluster randomized trials

横截面阶梯楔形整群随机试验中的中介分析

Mediation analysis has been comprehensively studied for independent data but relatively little work has been done for correlated data, especially for the increasingly adopted stepped wedge cluster randomized trials (SW-CRTs). Motivated by challenges in underlying the effect mechanisms in pragmatic and implementation science clinical trials, we develop new methods for mediation analysis in SW-CRTs. Specifically, based on a linear and generalized linear mixed models, we…

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MMCE: A Framework for Deep Monotonic Modeling of Multiple Causal Effects

MMCE:多重因果效应的深度单调建模框架

When we plan to use money as an incentive to change the behavior of a person (such as making riders to deliver more orders or making consumers to buy more items), the common approach of this problem is to adopt a two-stage framework in order to maximize ROI under cost constraints. In the first stage, the individual price response curve is obtained. In the second stage, business goals and resource constraints are formally expressed and modeled as an optimization problem. The…

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Causal Models for Growing Networks

增长网络的因果模型

Real-world networks grow over time; statistical models based on node exchangeability are not appropriate. Instead of constraining the structure of the \textit{distribution} of edges, we propose that the relevant symmetries refer to the \textit{causal structure} between them. We first enumerate the 96 causal directed acyclic graph (DAG) models over pairs of nodes (dyad variables) in a growing network with finite ancestral sets that are invariant to node deletion. We then…

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Dynamic Factor Analysis of High-dimensional Recurrent Events

高维重复事件的动态因子分析

Recurrent event time data arise in many studies, including biomedicine, public health, marketing, and social media analysis. High-dimensional recurrent event data involving many event types and observations have become prevalent with advances in information technology. This paper proposes a semiparametric dynamic factor model for the dimension reduction of high-dimensional recurrent event data. The proposed model imposes a low-dimensional structure on the mean intensity…

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Individualized Policy Evaluation and Learning under Clustered Network Interference

聚类网络干扰下的个体化政策评估与学习

Although there is now a large literature on policy evaluation and learning, much of the prior work assumes that the treatment assignment of one unit does not affect the outcome of another unit. Unfortunately, ignoring interference can lead to biased policy evaluation and ineffective learned policies. For example, treating influential individuals who have many friends can generate positive spillover effects, thereby improving the overall performance of an individualized…

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Addressing pitfalls in implicit unobserved confounding synthesis using explicit block hierarchical ancestral sampling

用显式分块层级祖先抽样改进不可观测混杂数据生成

Unbiased data synthesis is crucial for evaluating causal discovery algorithms in the presence of unobserved confounding, given the scarcity of real-world datasets. A common approach, implicit parameterization, encodes unobserved confounding by modifying the off-diagonal entries of the idiosyncratic covariance matrix while preserving positive definiteness. Within this approach, we identify that state-of-the-art protocols have two distinct issues that hinder unbiased sampling…

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Non-parametric cure models through extreme-value tail estimation

基于极值尾部估计的非参数治愈模型

In survival analysis, the estimation of the proportion of subjects who will never experience the event of interest, termed the cure rate, has received considerable attention recently. Its estimation can be a particularly difficult task when follow-up is not sufficient, that is when the censoring mechanism has a smaller support than the distribution of the target data. In the latter case, non-parametric estimators were recently proposed using extreme value methodology,…

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Unsupervised domain adaptation under hidden confounding

隐藏混杂下的无监督领域适应

We introduce a new predictive mechanism that operates in the presence of hidden confounding across distributionally diverse data sources while ensuring consistent estimation of causal parameters-despite their recognized suboptimality for prediction in the literature. Our method is based on a novel estimand that captures the dependence structure between response noise and covariates, incorporating causal parameters into a generative model that adaptively replicates the…

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Noise-Induced Randomization in Regression Discontinuity Designs

断点回归设计中的噪声诱导随机化

Regression discontinuity designs assess causal effects in settings where treatment is determined by whether an observed running variable crosses a pre-specified threshold. Here we propose a new approach to identification, estimation, and inference in regression discontinuity designs that uses knowledge about exogenous noise (e.g., measurement error) in the running variable. In our strategy, we weight treated and control units to balance a latent variable of which the running…

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Inference for Cumulative Incidences and Treatment Effects in Randomized Controlled Trials with Time-to-Event Outcomes under ICH E9 (R1)

ICH E9(R1)框架下随机试验累积发生率与处理效应的推断

In randomized controlled trials (RCTs) that focus on time-to-event outcomes, intercurrent events can arise in two ways: as semi-competing events, which modify the hazard of the primary outcome events, or as competing events, which make the definition of the primary outcome events unclear. Although five strategies have been proposed in the ICH E9 (R1) addendum to address intercurrent events in RCTs, these strategies are not easily applicable to time-to-event outcomes when…

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Relational Graph in Vector Autoregression: A Case Study on the Effect of the Great Recession on Connectivity of Economic Indicators

向量自回归中的关系图:大衰退与经济指标连接变化

Under a high-dimensional vector autoregressive (VAR) model, we propose a way of efficiently estimating both the stationary graph structure between the nodal time series and their temporal dynamics. The framework is then used to make inferences on the change in interdependencies between several economic indicators due to the impact of the Great Recession, the financial crisis that lasted from 2007 through 2009. There are several key advantages of the proposed framework; (1)…

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Incorporating Auxiliary Variables to Improve the Efficiency of Time-Varying Treatment Effect Estimation

利用辅助变量提高时变处理效应估计效率

Contextual sensing and delivery of digital interventions to improve health outcomes have gained significant traction in behavioral and psychiatric studies. Micro-randomized trials (MRTs) are a common experimental design for obtaining data-driven evidence on the effectiveness of digital interventions where each individual is repeatedly randomized to receive treatments over numerous time points. Throughout the study, individual characteristics and contextual factors around…

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Improving Transportability of Regression Calibration Under the Main/External Validation Study Design

改进主研究/外部验证研究设计下回归校准的可迁移性

In epidemiology, obtaining accurate individual exposure measurements can be costly and challenging. Thus, these measurements are often subject to error. Regression calibration with a validation study is widely employed as a study design and analysis method to correct for measurement error in the main study due to its broad applicability and simple implementation. However, relying on an external validation study to assess the measurement error process carries the risk of…

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Probabilistic Crop Yields Forecasts With Spatio-Temporal Conditional Copula Using Extreme Weather Covariates

结合极端天气协变量与时空条件 Copula 的作物产量概率预测

We introduce a novel forecasting model for crop yields that explicitly accounts for spatio-temporal dependence and the influence of extreme weather and climatic events. Our approach combines Bayesian Structural Time Series for modeling marginal crop yields, ensuring a more robust quantification of uncertainty given the typically short historical records. To capture dynamic dependencies between regions, we develop a time-varying conditional copula model, where the copula…

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A Unified Approach for Estimating Various Treatment Effects in Causal Inference

因果推断中多类处理效应的统一估计方法

In this paper, we introduce a unified estimator to analyze various treatment effects in causal inference, including but not limited to the average treatment effect (ATE) and the quantile treatment effect (QTE). The proposed estimator is developed under the statistical functional and cumulative distribution function structure, which leads to a flexible and robust estimator and covers some frequent treatment effects. In addition, our approach also takes variable selection into…

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tempdisagg: A Python Framework for Temporal Disaggregation of Time Series Data

tempdisagg:时间序列时间分解的 Python 框架

tempdisagg is a modern, extensible, and production-ready Python framework for temporal disaggregation of time series data. It transforms low-frequency aggregates into consistent, high-frequency estimates using a wide array of econometric techniques-including Chow-Lin, Denton, Litterman, Fernandez, and uniform interpolation-as well as enhanced variants with automated estimation of key parameters such as the autocorrelation coefficient rho. The package introduces features…

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Dynamic Regression Discontinuity: An Event-Study Approach

动态断点回归:事件研究方法

I propose a novel argument to identify economically interpretable intertemporal treatment effects in dynamic regression discontinuity designs (RDDs). Specifically, I develop a dynamic potential outcomes model and reformulate two assumptions from the difference-in-differences literature, no anticipation and common trends, to attain point identification of cutoff-specific impulse responses. The estimand of each target parameter can be expressed as the sum of two static RDD…

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Integrate Meta-analysis into Specific Study (InMASS) for Estimating Conditional Average Treatment Effect

将元分析整合到特定研究中以估计条件平均处理效应:InMASS

Randomized controlled trials are the standard method for estimating causal effects, ensuring sufficient statistical power and confidence through adequate sample sizes. However, achieving such sample sizes is often challenging. This study proposes a novel method for estimating the average treatment effect (ATE) in a target population by integrating and reconstructing information from previous trials using only summary statistics of outcomes and covariates through…

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Copula-based Sensitivity Analysis for Multi-Treatment Causal Inference with Unobserved Confounding

未观测混杂下多处理因果推断的copula敏感性分析

Recent work has focused on the potential and pitfalls of causal identification in observational studies with multiple simultaneous treatments. Building on previous work, we show that even if the conditional distribution of unmeasured confounders given treatments were known exactly, the causal effects would not in general be identifiable, although they may be partially identified. Given these results, we propose a sensitivity analysis method for characterizing the effects of…

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