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Structural restrictions in local causal discovery: identifying direct causes of a target variable

局部因果发现中的结构限制:识别目标变量的直接原因

We consider the problem of learning a set of direct causes of a target variable from an observational joint distribution. Learning directed acyclic graphs (DAGs) that represent the causal structure is a fundamental problem in science. Several results are known when the full DAG is identifiable from the distribution, such as assuming a nonlinear Gaussian data-generating process. Here, we are only interested in identifying the direct causes of one target variable (local causal…

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Efficient Difference-in-Differences and Event Study Estimators

高效的双重差分与事件研究估计量

This paper investigates efficient Difference-in-Differences (DiD) and Event Study (ES) estimation using short panel data sets within the heterogeneous treatment effect framework, free from parametric functional form assumptions and allowing for variation in treatment timing. We provide an equivalent characterization of the DiD potential outcome model using sequential conditional moment restrictions on observables, which shows that the DiD identification assumptions typically…

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Asymptotic theory for the likelihood-based block maxima method in time series

时间序列中基于似然的分块最大值方法的渐近理论

This paper develops a rigorous asymptotic framework for likelihood-based inference in the Block Maxima (BM) method for stationary time series. While Bayesian inference under the BM approach has been widely studied in the independence setting, no asymptotic theory currently exists for time series. Further results are needed to establish that BM method can be applied with the kind of dependent time series models relevant to applied fields. To address this gap we first…

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Autoregressive Hypergraph

自回归超图模型

Traditional graph representations are insufficient for modelling real-world phenomena involving multi-entity interactions, such as collaborative projects or protein complexes, necessitating the use of hypergraphs. While hypergraphs preserve the intrinsic nature of such complex relationships, existing models often overlook temporal evolution in relational data. To address this, we introduce a first-order autoregressive (i.e. AR(1)) model for dynamic non-uniform hypergraphs.…

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FedECA: Federated External Control Arms for Causal Inference with Time-To-Event Data in Distributed Settings

FedECA:分布式生存数据因果推断的联邦外部对照组

External control arms can inform early clinical development of experimental drugs and provide efficacy evidence for regulatory approval. However, accessing sufficient real-world or historical clinical trials data is challenging. Indeed, regulations protecting patients' rights by strictly controlling data processing make pooling data from multiple sources in a central server often difficult. To address these limitations, we develop a method that leverages federated learning…

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Dimension free ridge regression

无维度限制的岭回归

Random matrix theory has become a widely useful tool in high-dimensional statistics and theoretical machine learning. However, random matrix theory is largely focused on the proportional asymptotics in which the number of columns grows proportionally to the number of rows of the data matrix. This is not always the most natural setting in statistics where columns correspond to covariates and rows to samples. With the objective to move beyond the proportional asymptotics, we…

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Sequential Synthetic Difference in Differences

序贯合成双重差分

We propose the Sequential Synthetic Difference-in-Differences (Sequential SDiD) estimator for event studies with staggered treatment adoption, particularly when the parallel trends assumption fails. The method uses an iterative imputation procedure on aggregated data, where estimates for early-adopting cohorts are used to construct counterfactuals for later ones. We prove the estimator is asymptotically equivalent to an infeasible oracle OLS estimator within a linear model…

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Statistical Learning for Heterogeneous Treatment Effects: Pretraining, Prognosis, and Prediction

异质性处理效应的统计学习:预训练、预后与预测

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a valuable toolbox for causal estimation, enabling more flexible effect estimation. However, accurately estimating conditional average treatment effects (CATE) remains a major challenge, particularly in the presence of many covariates. In…

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TRUST: Transparent, Robust and Ultra-Sparse Trees

TRUST:透明、稳健且超稀疏的回归树

Piecewise-constant regression trees remain popular for their interpretability, yet often lag behind black-box models like Random Forest in predictive accuracy. In this work, we introduce TRUST (Transparent, Robust, and Ultra-Sparse Trees), a novel regression tree model that combines the accuracy of Random Forests with the interpretability of shallow decision trees and sparse linear models. TRUST further enhances transparency by leveraging Large Language Models to generate…

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Independent increments and group sequential tests

独立增量与组序贯检验

Widely used methods and software for group sequential tests of a null hypothesis of no treatment difference that allow for early stopping of a clinical trial depend primarily on the fact that sequentially-computed test statistics have the independent increments property. However, there are many practical situations where the sequentially-computed test statistics do not possess this property. Key examples are in trials where the primary outcome is a time to an event but where…

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Sensitivity Analysis of Priors in the Bayesian Dirichlet Auto-Regressive Moving Average Model

贝叶斯 Dirichlet 自回归移动平均模型的先验敏感性分析

Prior choice can strongly influence Bayesian Dirichlet ARMA (B-DARMA) inference for compositional time-series. Using simulations with (i) correct lag order, (ii) overfitting, and (iii) underfitting, we assess five priors: weakly-informative, horseshoe, Laplace, mixture-of-normals, and hierarchical. With the true lag order, all priors achieve comparable RMSE, though horseshoe and hierarchical slightly reduce bias. Under overfitting, aggressive shrinkage-especially the…

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Towards Robust Causal Effect Identification Beyond Markov Equivalence

超越马尔可夫等价类的稳健因果效应识别

Causal effect identification typically requires a fully specified causal graph, which can be difficult to obtain in practice. We provide a sufficient criterion for identifying causal effects from a candidate set of Markov equivalence classes with added background knowledge, which represents cases where determining the causal graph up to a single Markov equivalence class is challenging. Such cases can happen, for example, when the untestable assumptions (e.g. faithfulness)…

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KANITE: Kolmogorov-Arnold Networks for ITE estimation

KANITE:用于个体处理效应估计的 Kolmogorov–Arnold 网络

We introduce KANITE, a framework leveraging Kolmogorov-Arnold Networks (KANs) for Individual Treatment Effect (ITE) estimation under multiple treatments setting in causal inference. By utilizing KAN's unique abilities to learn univariate activation functions as opposed to learning linear weights by Multi-Layer Perceptrons (MLPs), we improve the estimates of ITEs. The KANITE framework comprises two key architectures: 1.Integral Probability Metric (IPM) architecture: This…

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Identifiable and interpretable nonparametric factor analysis

可识别且可解释的非参数因子分析

Factor models are widely used to reduce dimensionality in modeling high-dimensional data. However, there remains a need for models that can be reliably fit in modest sample sizes and are identifiable, interpretable, and flexible. To address this gap, we propose a NIFTY model that uses a linear factor structure with Gaussian residuals, but with a novel latent variable modeling structure. In particular, we model each latent variable as a one-dimensional nonlinear mapping of a…

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Fast computation of exact confidence intervals for randomized experiments with binary outcomes

二元结果随机实验精确置信区间的快速计算

Given a randomized experiment with binary outcomes, exact confidence intervals for the average causal effect of the treatment can be computed through a series of permutation tests. This approach requires minimal assumptions and is valid for all sample sizes, as it does not rely on large-sample approximations such as those implied by the central limit theorem. We show that these confidence intervals can be found in $O(n \log n)$ permutation tests in the case of balanced…

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Causal inference amid missingness-specific independencies and mechanism shifts

缺失特定独立性与机制变化下的因果推断

The recovery of causal effects in structural models with missing data often relies on $m$-graphs, which assume that missingness mechanisms do not directly influence substantive variables. Yet, in many real-world settings, missing data can alter decision-making processes, as the absence of key information may affect downstream actions and states. To overcome this limitation, we introduce $lm$-SCMs and $lm$-graphs, which extend $m$-graphs by integrating a label set that…

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Linear-Time Primitives for Algorithm Development in Graphical Causal Inference

图形因果推断算法开发的线性时间基础操作

We introduce CIfly, a framework for efficient algorithmic primitives in graphical causal inference that isolates reachability as a reusable core operation. It builds on the insight that many causal reasoning tasks can be reduced to reachability in purpose-built state-space graphs that can be constructed on the fly during traversal. We formalize a rule table schema for specifying such algorithms and prove they run in linear time. We establish CIfly as a more efficient…

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A New Fit Assessment Framework for Common Factor Models Using Generalized Residuals

利用广义残差评估共同因子模型拟合的新框架

Assessing fit in common factor models solely through the lens of mean and covariance structures, as is commonly done with conventional goodness-of-fit (GOF) assessments, may overlook critical aspects of misfit, potentially leading to misleading conclusions. To achieve more flexible fit assessment, we extend the theory of generalized residuals (Haberman & Sinharay, 2013), originally developed for models with categorical data, to encompass more general measurement models.…

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Quantile Treatment Effects in High Dimensional Panel Data

高维面板数据中的分位数处理效应

We introduce novel estimators for quantile causal effects with high dimensional panel data (large $N$ and $T$), where only one or a few units are affected by the intervention or policy. Our method extends the generalized synthetic control method \citep{xu_2017} from average treatment effects on the treated to quantile treatment effects on the treated, allowing the underlying factor structure to change across the quantile of the interested outcome distribution. Our method…

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On the relationship between prediction intervals, tests of sharp nulls and inference on realized treatment effects in settings with few treated units

少量处理单位下预测区间、尖锐原假设检验与已实现处理效应推断的关系

We study how inference methods for settings with few treated units that rely on treatment effect homogeneity extend to alternative inferential targets when treatment effects are heterogeneous -- namely, tests of sharp null hypotheses, inference on realized treatment effects, and prediction intervals. We show that inference methods for these alternative targets are deeply interconnected: they are either equivalent or become equivalent under additional assumptions. Our results…

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Missing data in non-stationary multivariate time series from digital studies in Psychiatry

精神医学数字研究中非平稳多元时间序列的缺失数据

Mobile technology (e.g., mobile phones and wearable devices) provides scalable methods for collecting physiological and behavioral biomarkers in patients' naturalistic settings, as well as opportunities for therapeutic advancements and scientific discoveries regarding the etiology of psychiatric illness. Continuous data collection through mobile devices generates highly complex data: entangled multivariate time series of outcomes, exposures, and covariates. Missing data is a…

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When are dynamical systems learned from time series data statistically accurate?

从时间序列学习的动力系统何时具有统计准确性?

Conventional notions of generalization often fail to describe the ability of learned models to capture meaningful information from dynamical data. A neural network that learns complex dynamics with a small test error may still fail to reproduce its \emph{physical} behavior, including associated statistical moments and Lyapunov exponents. To address this gap, we propose an ergodic theoretic approach to generalization of complex dynamical models learned from time series data.…

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Testing Goodness-of-Fit for Conditional Distributions: A New Perspective based on Principal Component Analysis

条件分布拟合优度检验:基于主成分分析的新视角

This paper introduces a novel goodness-of-fit test technique for parametric conditional distributions. The proposed tests are based on a residual marked empirical process, for which we develop a conditional Principal Component Analysis. The obtained components provide a basis for various types of new tests in addition to the omnibus one. Component tests that based on each component serve as experts in detecting certain directions. Smooth tests that assemble a few components…

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Identification of dynamic treatment effects when treatment histories are partially observed

处理历史部分可观测时动态处理效应的识别

This paper presents a general difference-in-differences framework for identifying path-dependent treatment effects when treatment histories are partially observed. We introduce a novel robust estimator that adjusts for missing histories using a combination of outcome, propensity score, and missing treatment models. We show that this approach identifies the target parameter as long as \textit{any two} of the three models are correctly specified. The method delivers improved…

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