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The Exact Variance of the Average Treatment Effect Estimator in Cluster Randomized Controlled Trials

整群随机对照试验中平均处理效应估计量的精确方差

In cluster randomized controlled trials (CRCT) with a finite populations, the exact design-based variance of the Horvitz-Thompson (HT) estimator for the average treatment effect (ATE) depends on the joint distribution of unobserved cluster-aggregated potential outcomes and is therefore not point-identifiable. We study a common two-stage sampling design-random sampling of clusters followed by sampling units within sampled clusters-with treatment assigned at the cluster level.…

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On the Hardness of Conditional Independence Testing In Practice

条件独立性检验在实践中的困难

Tests of conditional independence (CI) underpin a number of important problems in machine learning and statistics, from causal discovery to evaluation of predictor fairness and out-of-distribution robustness. Shah and Peters (2020) showed that, contrary to the unconditional case, no universally finite-sample valid test can ever achieve nontrivial power. While informative, this result (based on "hiding" dependence) does not seem to explain the frequent practical failures…

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Bayesian Global-Local Regularization

贝叶斯全局-局部正则化

We propose a unified framework for global-local regularization that bridges the gap between classical techniques -- such as ridge regression and the nonnegative garotte -- and modern Bayesian hierarchical modeling. By estimating local regularization strengths via marginal likelihood under order constraints, our approach generalizes Stein's positive-part estimator and provides a principled mechanism for adaptive shrinkage in high-dimensional settings. We establish that this…

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Theoretical Guarantees of Learning Ensembling Strategies with Applications to Time Series Forecasting

集成策略学习的理论保证及其时间序列预测应用

Ensembling is among the most popular tools in machine learning (ML) due to its effectiveness in minimizing variance and thus improving generalization. Most ensembling methods for black-box base learners fall under the umbrella of "stacked generalization," namely training an ML algorithm that takes the inferences from the base learners as input. While stacking has been widely applied in practice, its theoretical properties are poorly understood. In this paper, we prove a…

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Partially Retargeted Balancing Weights for Causal Effect Estimation Under Positivity Violations

正值性违背下用于因果效应估计的部分重定向平衡权重

Positivity violations, which occur when some subgroups either always or never receive a treatment of interest, pose significant challenges for causal effect estimation with observational data. Recent balancing weight methods have proved to be highly effective in confounding control, however their utility is diminished in the presence of positivity violations, resulting in bias and excess variance. Approaches that deal with positivity violations, on the other hand, work by…

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Testing identifying assumptions in Tobit Models

Tobit 模型识别假设的检验

We develop sharp, testable implications for the identifying assumptions of Tobit and IV-Tobit models: linear index, (joint) normality of errors, treatment (instrument) exogeneity, and relevance. The new sharp testable equalities can detect all possible observable violations of the identifying conditions. The proposed test procedure for the model's validity uses existing inference methods for intersection bounds. Simulations suggest adequate test size and power in detecting…

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Convergence of covariance and spectral density estimates for high-dimensional functional time series

高维函数型时间序列协方差与谱密度估计的收敛性

Second-order characteristics including covariance and spectral density functions are fundamentally important for both statistical applications and theoretical analysis in functional time series. In the high-dimensional setting where the number of functional variables is large relative to the length of functional time series, non-asymptotic theory for covariance function estimation has been developed for Gaussian and sub-Gaussian functional linear processes. However,…

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Testing Shape Restrictions with Continuous Treatment: A Transformation Model Approach

连续处理下的形状限制检验:变换模型方法

We propose tests for the convexity/linearity/concavity of a transformation of the dependent variable in a semiparametric transformation model. These tests can be used to verify monotonicity of the treatment effect, or, equivalently, concavity/convexity of the outcome with respect to the treatment, in (quasi-)experimental settings. Our procedure does not require estimation of the transformation or the distribution of the error terms. The statistic takes the form of a U…

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Clinical transfusion-outcomes research: A practical guide

临床输血结局研究:实用方法指南

Clinical transfusion-outcomes research faces unique methodological challenges compared with other areas of clinical research. These challenges arise because patients frequently receive multiple transfusions, each unit originates from a different donor, and the probability of receiving specific blood product characteristics is influenced by external, often uncontrollable, factors. These complexities complicate causal inference in observational studies of transfusion…

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Active multiple testing with proxy p-values and e-values

利用代理 p 值与 e 值的主动多重检验

Researchers often lack the resources to test every hypothesis of interest directly or compute test statistics comprehensively, but often possess auxiliary data from which we can compute an estimate of the experimental outcome. We introduce a novel approach for selecting which hypotheses to query a statistic (e.g., run an experiment, perform expensive computation, etc.) in a hypothesis testing setup by leveraging estimates to compute proxy statistics. Our framework allows a…

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Variational Inference for Fully Bayesian Hierarchical Linear Models

全贝叶斯分层线性模型的变分推断

Bayesian hierarchical linear models provide a natural framework to analyze nested and clustered data. Classical estimation with Markov chain Monte Carlo produces well calibrated posterior distributions but becomes computationally expensive in high dimensional or large sample settings. Variational Inference and Stochastic Variational Inference offer faster optimization based alternatives, but their accuracy in hierarchical structures is uncertain when group separation is…

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Uniform Quasi ML based inference for the panel AR(1) model

面板 AR(1) 模型中基于准极大似然的一致有效推断

Maximum Likelihood (ML) offers attractive alternatives to Generalized Method of Moments (GMM) estimators for dynamic panel data models. However, to date no identification-robust inference methods exist that can be used in conjunction with the ML estimators for these models. In this paper we propose ML based inference methods for panel AR(1) models with arbitrary initial conditions and heteroskedasticity that are robust to the strength of identification. We show that (Quasi)…

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Incorporating Interventional Independence Improves Robustness against Interventional Distribution Shift

利用干预独立性提高对干预分布偏移的稳健性

We study the problem of learning robust discriminative representations of causally related latent variables given the underlying causal graph and a training set comprising passively collected observational data and interventional data obtained through targeted interventions on some of these latent variables. We desire to learn representations that are robust against the resulting interventional distribution shifts. Existing approaches treat observational and interventional…

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Projected Bayesian Spatial Factor Models

投影贝叶斯空间因子模型

Factor models balance flexibility, identifiability, and computational efficiency, with Bayesian spatial factor models particularly prone to identifiability challenges and scaling limitations. This work introduces Projected Bayesian Spatial Factor (PBSF) models, a new class of models designed to achieve scalability and robust identifiability for spatial factor analysis. PBSF models are defined through a novel Markov chain Monte Carlo construction, Projected MCMC (ProjMC$^2$),…

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The Group R2D2 Shrinkage Prior for Sparse Linear Models with Grouped Covariates

面向分组协变量稀疏线性模型的 Group R2D2 收缩先验

Shrinkage priors are a popular Bayesian paradigm to handle sparsity in high-dimensional regression. Still limited, however, is a flexible class of shrinkage priors to handle grouped sparsity, where covariates exhibit some natural grouping structure. This paper proposes a novel extension of the $R^2$-induced Dirichlet Decomposition (R2D2) prior to accommodate grouped variable selection in linear regression models. The proposed method, called the Group R2D2 prior, employs a…

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Nonparametric Uniform Inference in Binary Classification and Policy Values

二元分类与政策价值的非参数一致推断

We develop methods for nonparametric uniform inference in cost-sensitive binary classification, a framework that encompasses maximum score estimation, predicting utility maximizing actions, and policy learning. These problems are well known for slow convergence rates and non-standard limiting behavior, even under point identified parametric frameworks. In nonparametric settings, they may further suffer from failures of identification. To address these challenges, we…

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Estimation of a Dynamic Tobit Model with a Unit Root

具有单位根的动态 Tobit 模型估计

This paper studies robust estimation in the dynamic Tobit model under local-to-unity (LUR) asymptotics. We show that both Gaussian maximum likelihood (ML) and censored least absolute deviations (CLAD) estimators are consistent, extending results from the stationary case where ordinary least squares (OLS) is inconsistent. The asymptotic distributions of MLE and CLAD are derived; for the short-run parameters they are shown to be Gaussian, yielding standard normal t-statistics.…

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Continuous difference-in-differences with double/debiased machine learning

结合双重/去偏机器学习的连续处理双重差分

This paper extends difference-in-differences to settings with continuous treatments. Specifically, the average treatment effect on the treated (ATT) at any level of treatment intensity is identified under a conditional parallel trends assumption. Estimating the ATT in this framework requires first estimating infinite-dimensional nuisance parameters, particularly the conditional density of the continuous treatment, which can introduce substantial bias. To address this…

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Proximal Causal Inference for Modified Treatment Policies

修改处理政策的近端因果推断

The proximal causal inference framework enables the identification and estimation of causal effects in the presence of unmeasured confounding by leveraging two disjoint sets of observed strong proxies: negative control treatments and negative control outcomes. In the point exposure setting, this framework has primarily been applied to estimands comparing counterfactual outcomes under a static fixed intervention or, possibly randomized, regime that depends on baseline…

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Assumption-Lean Post-Integrated Inference with Surrogate Control Outcomes

利用替代控制结果进行弱假设数据整合后推断

Data integration methods aim to extract low-dimensional embeddings from high-dimensional outcomes to remove unwanted variations, such as batch effects and unmeasured covariates, across heterogeneous datasets. However, multiple hypothesis testing after integration can be biased due to data-dependent processes. We introduce a robust post-integrated inference method that accounts for latent heterogeneity by utilizing control outcomes. Leveraging causal interpretations, we…

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Estimating the Effects of Heatwaves on Health: A Causal Inference Framework

热浪健康效应的估计:因果推断框架

The harmful relationship between heatwaves and health has been extensively documented in medical and epidemiological literature. However, most evidence is associational and cannot be interpreted causally unless strong assumptions are made. In this paper, we first make explicit the assumptions underlying the statistical methods frequently used in the heatwave literature and demonstrate when these assumptions might break down in heatwave contexts. To address these…

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Network Estimation for Stationary Time Series

平稳时间序列的网络估计

High-dimensional multivariate time series are common in many scientific and industrial applications, where the interest lies in identifying key dependence structure within the data for subsequent analysis tasks, such as forecasting. An important avenue to achieve this is through the estimation of the conditional independence graph via graphical models, although for time series data settings the underpinning temporal dependence can make this task challenging. In this article,…

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Confirmatory Biomarker Identification with k-FWER Control Using Derandomized Knockoffs with Cox Regression

基于去随机化 Knockoffs 与 Cox 回归的 k-FWER 控制确认性生物标志物识别

Selecting important features in high-dimensional survival analysis is critical for identifying confirmatory biomarkers while maintaining rigorous error control. In this paper, we propose a derandomized knockoffs procedure for Cox regression that enhances stability in feature selection while maintaining rigorous control over the k-familywise error rate (k-FWER). By aggregating across multiple randomized knockoff realizations, our approach mitigates the instability commonly…

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Testing Parametric Distribution Family Assumptions via Differences in Differential Entropy

利用微分熵差异检验参数分布族假设

We introduce a broadly applicable statistical procedure for testing which parametric distribution family generated a random sample of data. The method, termed the Difference in Differential Entropy (DDE) test, provides a unified framework applicable to a wide range of distributional families, with asymptotic validity grounded in established maximum likelihood, bootstrap, and kernel density estimation principles. The test is straightforward to implement, computationally…

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