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Causal Discovery with Fewer Conditional Independence Tests

用更少的条件独立检验进行因果发现

Many questions in science center around the fundamental problem of understanding causal relationships. However, most constraint-based causal discovery algorithms, including the well-celebrated PC algorithm, often incur an exponential number of conditional independence (CI) tests, posing limitations in various applications. Addressing this, our work focuses on characterizing what can be learned about the underlying causal graph with a reduced number of CI tests. We show that…

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Random Subspace Local Projections

随机子空间局部投影

We show how random subspace methods can be adapted to estimating local projections with many controls. Random subspace methods have their roots in the machine learning literature and are implemented by averaging over regressions estimated over different combinations of subsets of these controls. We document three key results: (i) Our approach can successfully recover the impulse response functions across Monte Carlo experiments representative of different macroeconomic…

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Local Discovery by Partitioning: Polynomial-Time Causal Discovery Around Exposure-Outcome Pairs

通过分割实现暴露—结果对的多项式时间局部因果发现

Causal discovery is crucial for causal inference in observational studies, as it can enable the identification of valid adjustment sets (VAS) for unbiased effect estimation. However, global causal discovery is notoriously hard in the nonparametric setting, with exponential time and sample complexity in the worst case. To address this, we propose local discovery by partitioning (LDP): a local causal discovery method that is tailored for downstream inference tasks without…

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Matrix-valued Factor Model with Time-varying Main Effects

具有时变主效应的矩阵值因子模型

We introduce the matrix-valued time-varying Main Effects Factor Model (MEFM). MEFM is a generalization to the traditional matrix-valued factor model (FM). We give rigorous definitions of MEFM and its identifications, and propose estimators for the time-varying grand mean, row and column main effects, and the row and column factor loading matrices for the common component. Rates of convergence for different estimators are spelt out, with asymptotic normality shown. The core…

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CaRiNG: Learning Temporal Causal Representation under Non-Invertible Generation Process

CaRiNG:非可逆生成过程下的时序因果表征学习

Identifying the underlying time-delayed latent causal processes in sequential data is vital for grasping temporal dynamics and making downstream reasoning. While some recent methods can robustly identify these latent causal variables, they rely on strict assumptions about the invertible generation process from latent variables to observed data. However, these assumptions are often hard to satisfy in real-world applications containing information loss. For instance, the…

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Stochastic Optimization Algorithms for Instrumental Variable Regression with Streaming Data

流式数据工具变量回归的随机优化算法

We develop and analyze algorithms for instrumental variable regression by viewing the problem as a conditional stochastic optimization problem. In the context of least-squares instrumental variable regression, our algorithms neither require matrix inversions nor mini-batches and provides a fully online approach for performing instrumental variable regression with streaming data. When the true model is linear, we derive rates of convergence in expectation, that are of order $\mathcal{O}(\log T/T)$…

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Do Finetti: On Causal Effects for Exchangeable Data

Do Finetti:可交换数据的因果效应

We study causal effect estimation in a setting where the data are not i.i.d. (independent and identically distributed). We focus on exchangeable data satisfying an assumption of independent causal mechanisms. Traditional causal effect estimation frameworks, e.g., relying on structural causal models and do-calculus, are typically limited to i.i.d. data and do not extend to more general exchangeable generative processes, which naturally arise in multi-environment data. To…

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Sharp and Robust Estimation of Partially Identified Discrete Response Models

部分识别离散响应模型的锐性与稳健估计

Semiparametric discrete choice models are widely used in a variety of practical applications. While these models are point identified in the presence of continuous covariates, they can become partially identified when covariates are discrete. In this paper we find that classical estimators, including the maximum score estimator, (Manski (1975)), loose their attractive statistical properties without point identification. First of all, they are not sharp with the estimator…

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Two-way fixed effects instrumental variable regressions in staggered DID-IV designs

交错 DID-IV 设计中的双向固定效应工具变量回归

Many studies run two-way fixed effects instrumental variable (TWFEIV) regressions, leveraging variation in the timing of policy adoption across units as an instrument for treatment. This paper studies the properties of the TWFEIV estimator in staggered instrumented difference-in-differences (DID-IV) designs. We show that in settings with the staggered adoption of the instrument across units, the TWFEIV estimator can be decomposed into a weighted average of all possible…

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Automating the Selection of Proxy Variables of Unmeasured Confounders

自动选择未观测混杂因素的代理变量

Recently, interest has grown in the use of proxy variables of unobserved confounding for inferring the causal effect in the presence of unmeasured confounders from observational data. One difficulty inhibiting the practical use is finding valid proxy variables of unobserved confounding to a target causal effect of interest. These proxy variables are typically justified by background knowledge. In this paper, we investigate the estimation of causal effects among multiple…

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Item-Level Heterogeneous Treatment Effects of Selective Serotonin Reuptake Inhibitors (SSRIs) on Depression: Implications for Inference, Generalizability, and Identification

SSRIs 对抑郁症的条目层面异质性治疗效应

In analysis of randomized controlled trials (RCTs) with patient-reported outcome measures (PROMs), Item Response Theory (IRT) models that allow for heterogeneity in the treatment effect at the item level merit consideration. These models for ``item-level heterogeneous treatment effects'' (IL-HTE) can provide more accurate statistical inference, allow researchers to better generalize their results, and resolve critical identification problems in the estimation of interaction…

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Causal de Finetti: On the Identification of Invariant Causal Structure in Exchangeable Data

因果 de Finetti:可交换数据中不变因果结构的识别

Constraint-based causal discovery methods leverage conditional independence tests to infer causal relationships in a wide variety of applications. Just as the majority of machine learning methods, existing work focuses on studying $\textit{independent and identically distributed}$ data. However, it is known that even with infinite i.i.d.$\ $ data, constraint-based methods can only identify causal structures up to broad Markov equivalence classes, posing a fundamental…

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Optimal Categorical Instrumental Variables

最优分类工具变量

This paper discusses estimation with a categorical instrumental variable in settings with potentially few observations per category. The proposed categorical instrumental variable estimator (CIV) leverages a regularization assumption that implies existence of a latent categorical variable with fixed finite support achieving the same first stage fit as the observed instrument. In asymptotic regimes that allow the number of observations per category to grow at arbitrary small…

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2SLS with Multiple Treatments

多重处理下的两阶段最小二乘法

We study what two-stage least squares (2SLS) identifies in models with multiple treatments under treatment effect heterogeneity. Two conditions are shown to be necessary and sufficient for the 2SLS to identify positively weighted sums of agent-specific effects of each treatment: average conditional monotonicity and no cross effects. Our identification analysis allows for any number of treatments, any number of continuous or discrete instruments, and the inclusion of…

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Quasi Maximum Likelihood Estimation of High-Dimensional Factor Models: A Critical Review

高维因子模型的拟极大似然估计:批判性综述

We review Quasi Maximum Likelihood estimation of factor models for high-dimensional panels of time series. We consider two cases: (1) estimation when no dynamic model for the factors is specified (Bai and Li, 2012, 2016); (2) estimation based on the Kalman smoother and the Expectation Maximization algorithm thus allowing to model explicitly the factor dynamics (Doz et al., 2012, Barigozzi and Luciani, 2019). Our interest is in approximate factor models, i.e., when we allow…

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A pseudo-outcome-based framework to analyze treatment heterogeneity in survival data using electronic health records

利用电子健康记录分析生存治疗效应异质性的伪结果框架

An important aspect of precision medicine focuses on characterizing diverse responses to treatment due to unique patient characteristics, also known as heterogeneous treatment effects (HTE), and identifying beneficial subgroups with enhanced treatment effects. Estimating HTE with right-censored data in observational studies remains challenging. In this paper, we propose a pseudo-outcome-based framework for analyzing HTE in survival data, which includes a list of…

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Mediation Analysis with Mendelian Randomization and Efficient Multiple GWAS Integration

基于孟德尔随机化与多项 GWAS 高效整合的中介分析

Mediation analysis is a powerful tool for studying causal pathways between exposure, mediator, and outcome variables of interest. While classical mediation analysis using observational data often requires strong and sometimes unrealistic assumptions, such as unconfoundedness, Mendelian Randomization (MR) avoids unmeasured confounding bias by employing genetic variations as instrumental variables. We develop a novel MR framework for mediation analysis with genome-wide…

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Optimizing Sales Forecasts through Automated Integration of Market Indicators

通过自动整合市场指标优化销售预测

Recognizing that traditional forecasting models often rely solely on historical demand, this work investigates the potential of data-driven techniques to automatically select and integrate market indicators for improving customer demand predictions. By adopting an exploratory methodology, we integrate macroeconomic time series, such as national GDP growth, from the \textit{Eurostat} database into \textit{Neural Prophet} and \textit{SARIMAX} forecasting models. Suitable time…

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Latent group structure in linear panel data models with endogenous regressors

含内生解释变量的线性面板模型中的潜在群组结构

This paper concerns the estimation of linear panel data models with endogenous regressors and a latent group structure in the coefficients. We consider instrumental variables estimation of the group-specific coefficient vector. We show that direct application of the Kmeans algorithm to the generalized method of moments objective function does not yield unique estimates. We newly develop and theoretically justify two-stage estimation methods that apply the Kmeans algorithm to…

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Studying continuous, time-varying, and/or complex exposures using longitudinal modified treatment policies

用纵向修正处理政策研究连续、时变及复杂暴露

This tutorial discusses methodology for causal inference using longitudinal modified treatment policies. This method facilitates the mathematical formalization, identification, and estimation of many novel parameters, and mathematically generalizes many commonly used parameters, such as the average treatment effect. Longitudinal modified treatment policies apply to a wide variety of exposures, including binary, multivariate, and continuous, and can accommodate time-varying…

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An adaptive enrichment design using Bayesian model averaging for selection and threshold-identification of tailoring variables

用贝叶斯模型平均选择个体化变量及识别阈值的自适应富集设计

Precision medicine stands as a transformative approach in healthcare, offering tailored treatments that can enhance patient outcomes and reduce healthcare costs. As understanding of complex disease improves, clinical trials are being designed to detect subgroups of patients with enhanced treatment effects. Biomarker-driven adaptive enrichment designs, which enroll a general population initially and later restrict accrual to treatment-sensitive patients, are gaining…

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Large-dimensional Robust Factor Analysis with Group Structure

具有群组结构的高维稳健因子分析

In this paper, we focus on exploiting the group structure for large-dimensional factor models, which captures the homogeneous effects of common factors on individuals within the same group. In view of the fact that datasets in macroeconomics and finance are typically heavy-tailed, we propose to identify the unknown group structure using the agglomerative hierarchical clustering algorithm and an information criterion with the robust two-step (RTS) estimates as initial values.…

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Interactive identification of individuals with positive treatment effect while controlling false discoveries

在控制错误发现率的同时交互式识别具有正向处理效应的个体

Out of the participants in a randomized experiment with anticipated heterogeneous treatment effects, is it possible to identify which subjects have a positive treatment effect? While subgroup analysis has received attention, claims about individual participants are much more challenging. We frame the problem in terms of multiple hypothesis testing: each individual has a null hypothesis (stating that the potential outcomes are equal, for example) and we aim to identify those…

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On the Non-Identification of Revenue Production Functions

收入生产函数的不可识别性

Production functions are potentially misspecified when revenue is used as a proxy for output. I formalize and strengthen this common knowledge by showing that neither the production function nor Hicks-neutral productivity can be identified with such a revenue proxy. This result obtains when relaxing the standard assumptions used in the literature to allow for imperfect competition. It holds for a large class of production functions, including all commonly used parametric…

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