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Randomization Inference When N Equals One

样本量为一时的随机化推断

N-of-1 experiments, where a unit serves as its own control and treatment in different time windows, have been used in certain medical contexts for decades. However, due to effects that accumulate over long time windows and interventions that have complex evolution, a lack of robust inference tools has limited the widespread applicability of such N-of-1 designs. This work combines techniques from experiment design in causal inference and system identification from control…

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Heckman Selection Contaminated Normal Model

采用污染正态分布的 Heckman 选择模型

The Heckman selection model is one of the most well-renounced econometric models in the analysis of data with sample selection. This model is designed to rectify sample selection biases based on the assumption of bivariate normal error terms. However, real data diverge from this assumption in the presence of heavy tails and/or atypical observations. Recently, this assumption has been relaxed via a more flexible Student's t-distribution, which has appealing statistical…

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Selecting Subpopulations for Causal Inference in Regression Discontinuity Designs

断点回归设计中因果推断子总体的选择

The Brazil Bolsa Familia (BF) program is a conditional cash transfer program aimed to reduce short-term poverty by direct cash transfers and to fight long-term poverty by increasing human capital among poor Brazilian people. Eligibility for Bolsa Familia benefits depends on a cutoff rule, which classifies the BF study as a regression discontinuity (RD) design. Extracting causal information from RD studies is challenging. Following Li et al (2015) and Branson and Mealli…

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Cluster randomized trials designed to support generalizable inferences

支持可推广推断的整群随机试验设计

Background: When planning a cluster randomized trial, evaluators often have access to an enumerated cohort representing the target population of clusters. Practicalities of conducting the trial, such as the need to oversample clusters with certain characteristics to improve trial economy or to support inference about subgroups of clusters, may preclude simple random sampling from the cohort into the trial, and thus interfere with the goal of producing generalizable…

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Group Sequential Testing of a Treatment Effect Using a Surrogate Marker

利用替代指标对处理效应进行群序贯检验

The identification of surrogate markers is motivated by their potential to make decisions sooner about a treatment effect. However, few methods have been developed to actually use a surrogate marker to test for a treatment effect in a future study. Most existing methods consider combining surrogate marker and primary outcome information to test for a treatment effect, rely on fully parametric methods where strict parametric assumptions are made about the relationship between…

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Bridging multiple worlds: multi-marginal optimal transport for causal partial-identification problem

连接多个潜在世界:因果部分识别的多边际最优传输方法

Under the prevalent potential outcome model in causal inference, each unit is associated with multiple potential outcomes but at most one of which is observed, leading to many causal quantities being only partially identified. The inherent missing data issue echoes the multi-marginal optimal transport (MOT) problem, where marginal distributions are known, but how the marginals couple to form the joint distribution is unavailable. In this paper, we cast the causal partial…

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Identifiable causal inference with noisy treatment and no side information

处理变量含噪且无辅助信息时的可识别因果推断

In some causal inference scenarios, the treatment variable is measured inaccurately, for instance in epidemiology or econometrics. Failure to correct for the effect of this measurement error can lead to biased causal effect estimates. Previous research has not studied methods that address this issue from a causal viewpoint while allowing for complex nonlinear dependencies and without assuming access to side information. For such a scenario, this study proposes a model that…

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Identification and multiply robust estimation in causal mediation analysis across principal strata

主分层间因果中介分析的识别与多重稳健估计

We consider assessing causal mediation in the presence of a post-treatment event (examples include noncompliance, a clinical event, or death). We identify natural mediation effects for the entire study population and for each principal stratum characterized by the joint potential values of the post-treatment event. We derive the efficient influence function for each mediation estimand, which motivates a set of multiply robust estimators for inference. The multiply robust…

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The First-stage F Test with Many Weak Instruments

大量弱工具变量下的第一阶段 F 检验

A widely adopted approach for detecting weak instruments is to use the first-stage $F$ statistic. While this method was developed with a fixed number of instruments, its performance with many instruments remains insufficiently explored. We show that the first-stage $F$ test exhibits distorted sizes for detecting many weak instruments, regardless of the choice of pretested estimators or Wald tests. These distortions occur due to the inadequate approximation using classical…

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Anytime-Valid Inference for Double/Debiased Machine Learning of Causal Parameters

因果参数双重去偏机器学习的任意时点有效推断

Double (debiased) machine learning (DML) has seen widespread use in recent years for learning causal/structural parameters, in part due to its flexibility and adaptability to high-dimensional nuisance functions as well as its ability to avoid bias from regularization or overfitting. However, the classic double-debiased framework is only valid asymptotically for a predetermined sample size, thus lacking the flexibility of collecting more data if sharper inference is needed,…

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Estimation and Inference for Causal Functions with Multiway Clustered Data

多维聚类数据下因果函数的估计与推断

This paper proposes methods of estimation and uniform inference for a general class of causal functions, such as the conditional average treatment effects and the continuous treatment effects, under multiway clustering. The causal function is identified as a conditional expectation of an adjusted (Neyman-orthogonal) signal that depends on high-dimensional nuisance parameters. We propose a two-step procedure where the first step uses machine learning to estimate the…

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Common Trends and Long-Run Identification in Nonlinear Structural VARs

非线性结构 VAR 中的共同趋势与长期识别

While it is widely recognised that linear (structural) VARs may fail to capture important aspects of economic time series, the use of nonlinear SVARs has to date been almost entirely confined to the modelling of stationary time series, because of a lack of understanding as to how common stochastic trends may be accommodated within nonlinear models. This has unfortunately circumscribed the range of series to which such models can be applied -- and/or required that these…

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Transfer Learning for Spatial Autoregressive Models with Application to U.S. Presidential Election Prediction

空间自回归模型的迁移学习及美国总统选举预测应用

It is important to incorporate spatial geographic information into U.S. presidential election analysis, especially for swing states. The state-level analysis also faces significant challenges of limited spatial data availability. To address the challenges of spatial dependence and small sample sizes in predicting U.S. presidential election results using spatially dependent data, we propose a novel transfer learning framework within the SAR model, called as tranSAR. Classical…

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Extreme Quantile Treatment Effects under Endogeneity: Evaluating Policy Effects for the Most Vulnerable Individuals

内生性下的极端分位数处理效应:评估最弱势群体的政策效果

We introduce a novel method for estimating and conducting inference about extreme quantile treatment effects (QTEs) in the presence of endogeneity. Our approach is applicable to a broad range of empirical research designs, including instrumental variables design and regression discontinuity design, among others. By leveraging regular variation and subsampling, the method ensures robust performance even in extreme tails, where data may be sparse or entirely absent. Simulation…

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Co-Developing Causal Graphs with Domain Experts Guided by Weighted FDR-Adjusted p-values

以加权多重检验调整后的 p 值辅助领域专家共建因果图

This paper proposes an approach facilitating co-design of causal graphs between subject matter experts and statistical modellers. Modern causal analysis starting with formulation of causal graphs provides benefits for robust analysis and well-grounded decision support. Moreover, this process can enrich the discovery and planning phase of data science projects. The key premise is that plotting relevant statistical information on a causal graph structure can facilitate an…

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Penalized Subgrouping of Heterogeneous Time Series

异质性时间序列的惩罚化子群划分

Interest in the study and analysis of dynamic processes in the social, behavioral, and health sciences has burgeoned in recent years due to the increased availability of intensive longitudinal data. However, how best to model and account for the persistent heterogeneity characterizing such processes remains an open question. The multi-VAR framework, a recent methodological development built on the vector autoregressive model, accommodates heterogeneous dynamics in…

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Safe Policy Learning under Regression Discontinuity Designs with Multiple Cutoffs

多阈值断点回归设计下的安全政策学习

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

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Learning linear acyclic causal model including Gaussian noise using ancestral relationships

利用祖先关系学习含高斯噪声的线性无环因果模型

This paper discusses algorithms for learning causal DAGs. The PC algorithm makes no assumptions other than the faithfulness to the causal model and can identify only up to the Markov equivalence class. LiNGAM assumes linearity and continuous non-Gaussian disturbances for the causal model, and the causal DAG defining LiNGAM is shown to be fully identifiable. The PC-LiNGAM, a hybrid of the PC algorithm and LiNGAM, can identify up to the distribution-equivalence pattern of a…

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Long-term Causal Inference Under Persistent Confounding via Data Combination

持续混杂下通过数据结合开展长期因果推断

We study the identification and estimation of long-term treatment effects when both experimental and observational data are available. Since the long-term outcome is observed only after a long delay, it is not measured in the experimental data, but only recorded in the observational data. However, both types of data include observations of some short-term outcomes. In this paper, we uniquely tackle the challenge of persistent unmeasured confounders, i.e., some unmeasured…

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Invariant Causal Prediction with Local Models

使用局部模型的不变因果预测

We consider the task of identifying the causal parents of a target variable among a set of candidates from observational data. Our main assumption is that the candidate variables are observed in different environments which may, under certain assumptions, be regarded as interventions on the observed system. We assume a linear relationship between target and candidates, which can be different in each environment with the only restriction that the causal structure is invariant…

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Effect Aliasing in Observational Studies

观察性研究中的效应混叠

In experimental design, aliasing of effects occurs in fractional factorial experiments, where certain low order factorial effects are indistinguishable from certain high order interactions: low order contrasts may be orthogonal to one another, while their higher order interactions are aliased and not identified. In observational studies, aliasing occurs when certain combinations of covariates -- e.g., time period and various eligibility criteria for treatment -- perfectly…

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Enabling Causal Discovery in Post-Nonlinear Models with Normalizing Flows

用归一化流实现后非线性模型的因果发现

Post-nonlinear (PNL) causal models stand out as a versatile and adaptable framework for modeling intricate causal relationships. However, accurately capturing the invertibility constraint required in PNL models remains challenging in existing studies. To address this problem, we introduce CAF-PoNo (Causal discovery via Normalizing Flows for Post-Nonlinear models), harnessing the power of the normalizing flows architecture to enforce the crucial invertibility constraint in…

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Intervention effects based on potential benefit

基于潜在获益的干预效应

Optimal treatment rules are mappings from individual patient characteristics to tailored treatment assignments that maximize mean outcomes. In this work, we introduce a conditional potential benefit (CPB) metric that measures the expected improvement under an optimally chosen treatment compared to the status quo, within covariate strata. The potential benefit combines (i) the magnitude of the treatment effect, and (ii) the propensity for subjects to naturally select a…

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Revisiting Panel Data Discrete Choice Models with Lagged Dependent Variables

重新研究含滞后因变量的面板离散选择模型

This paper revisits the identification and estimation of a class of semiparametric (distribution-free) panel data binary choice models with lagged dependent variables, exogenous covariates, and entity fixed effects. We provide a novel identification strategy, using an "identification at infinity" argument. In contrast with the celebrated Honore and Kyriazidou (2000), our method permits time trends of any form and does not suffer from the "curse of dimensionality". We propose…

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