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利用信息性缺失学习多模态临床时间序列的动态表征与策略AI 解读

Multimodal clinical records contain structured measurements and clinical notes recorded over time, offering rich temporal information about the evolution of patient health. Yet these observations are sparse, and whether they are recorded depends on the patient's latent condition. Observation patterns also differ across modalities, as structured measurements and clinical notes arise under distinct recording processes. While prior work has developed methods that accommodate…

限价订单簿潜在微观结构状态的早期检测AI 解读

Limit order books can transition rapidly from stable to stressed conditions, yet standard early-warning signals such as order flow imbalance and short-term volatility are inherently reactive. We formalise this limitation via a three-regime causal data-generating process (stable $\to$ latent build-up $\to$ stress) in which a latent deterioration phase creates a prediction window prior to observable stress. Under mild assumptions on temporal drift and regime persistence, we…

通过均值或效应尺度可迁移性构造外部对照组AI 解读

Learning about causal effects in target populations and their subsets may be facilitated by combining information from multiple sources. One major class of study designs that combine information involves appending an index study with data from an external comparator, which may facilitate head-to-head comparisons of treatments initially studied in different populations. We delineate external comparator analyses under two distinct, but related, identification strategies. The…

随机前沿模型因果分析的近期进展AI 解读

Causal inference methods (instrumental variables, difference-in-differences, regression discontinuity, etc.) are primary tools used across many social science milieus. One area where their application has lagged however, is in the study of productivity and efficiency. A main reason for this is that the nature of the stochastic frontier model does not immediately lend itself to a causal framework when interest hinges on an error component of the model. This paper reviews the…

基于经验似然的标签噪声下Neyman-Pearson多分类AI 解读

In many classification problems, misclassification costs are highly asymmetric, while training labels are often corrupted due to measurement error, annotator variability, or adversarial noise. The Neyman-Pearson multiclass classification (NPMC) framework addresses such asymmetry by controlling class-specific errors, but existing methods assume that training labels are correctly observed. To our knowledge, no existing approach handles NPMC under label noise in the multiclass…

高维数据中适应缺失模式的因子识别AI 解读

Determining the number of factors in high-dimensional factor models remains a fundamental challenge, particularly when data are incomplete. This paper introduces the concept of identifiable factors, those that can be reliably recovered despite missing observations, and proposes the Missingness-Adaptive Thresholding Estimator (MATE). To our knowledge, MATE is the first missingness-adaptive framework for factor number determination that accommodates both homogeneous and…

机器学习驱动的线性工具变量模型设定检验AI 解读

The linear instrumental variable (IV) model is widely used in observational studies, yet its validity hinges on strong assumptions. Classical specification tests such as the Sargan-Hansen J test are limited to overidentified settings and are therefore not applicable in the common just-identified case, where the number of instruments is equal to the number of endogenous variables. We propose a novel test for the well-specification of the linear IV model under the assumption…

社会网络形成的因果推断AI 解读

This paper develops a framework for identification, estimation, and inference on the causal mechanisms driving endogenous social network formation. Identification is challenging because of unobserved confounders and reverse causality; inference is complicated by questions of equilibrium and sampling. We leverage repeated observations of a network over time and random variation in initial ties to address challenges to causal identification. Our design-based approach sidesteps…

主层可忽略性违反时主层因果效应的部分识别AI 解读

Principal stratification is a general framework for studying causal mechanisms involving post-treatment variables. When estimating principal causal effects, the principal ignorability assumption is commonly invoked, which we study in detail in this manuscript. Our first key contribution is studying a commonly used strategy of using parametric models to jointly model the outcome and principal strata without requiring the principal ignorability assumption. We show that even if…

单侧不依从随机对照试验中的依从者一般因果效应AI 解读

A randomized controlled trial (RCT) is widely regarded as the gold standard for assessing the causal effect of a treatment or intervention, assuming perfect implementation. In practice, however, randomization can be compromised for various reasons, such as one-sided noncompliance. In this paper, we first systematically study the likelihood-based identifiability in an RCT with one-sided noncompliance. This foundational analysis naturally gives rise to the complier general…

内生处理分配下已处理者平均处理效应的有效估计AI 解读

In this paper, we consider estimation of average treatment effect on the treated (ATT), an interpretable and relevant causal estimand to policy makers when treatment assignment is endogenous. By considering shadow variables that are unrelated to the treatment assignment but related to the outcomes of interest, we establish identification of the ATT. Then we focus on efficient estimation of the ATT by characterizing the geometric structure of the likelihood, deriving the…

将诊断检验融入估计AI 解读

Empirical researchers often use diagnostic checks to assess the plausibility of their modeling assumptions, such as testing for covariate balance in RCTs, pre-trends in event studies, or instrument validity in IV designs. While these checks are traditionally treated as external hurdles to estimation, we argue they should be integrated into the estimation process itself. In particular, we propose residualizing one's baseline estimator against the vector of diagnostic check…

高维因子模型中多重断点的分类与估计AI 解读

This paper proposes a quasi-maximum likelihood (QML) estimator for break points in high-dimensional factor models, specifically accounting for multiple structural breaks. We begin by establishing a necessary and sufficient condition to categorize two distinct types of breaks in factor loadings: singular changes and rotational changes. The analysis of the nearly singular subsample covariance matrices of the pseudo-factors plays a key role in our approach. It allows us to…

带连续标记的删失数据因果推断AI 解读

This paper presents a framework for causal inference in the presence of censored data,where the failure time is marked by a continuous variable referred to as a mark.The mark is observed after treatment and is not meaningful when the failure time is censored. In addition, due to the continuous nature of the marks, observations at each given mark are sparse. These facts make the identification and estimation of causality a challenging task. To address these issues, we define…

Jackknife 工具变量推断AI 解读

This paper introduces a class of jackknife-based test statistics for linear regression models with endogeneity and heteroskedasticity in the presence of many potentially weak instrumental variables. The tests may be used when considering hypotheses on the full parameter vector or hypotheses defined as linear restrictions. We show that in the limit and under the null the proposed statistics are distributed as a combination of chi squares but by modifying the objective…

Pearl 前门准则的推广AI 解读

Pearl's front-door criterion provides a set of sufficient conditions for estimating the total causal effect from observational data in the presence of latent confounding, using the functional P(y | do(x := x*)) = \sum_z P(z | x*) \sum_x P(y | x, z) P(x). An open question is whether these conditions can be generalized to be both necessary and sufficient for the validity of this functional, similar to the generalization achieved for the back-door adjustment criterion by…

高维广义线性模型的自适应多先验 LassoAI 解读

Incorporation of external information into high-dimensional modeling for gene expression data has been shown, both theoretically and empirically, to substantially enhance performance. Such external information, sometimes referred to as prior information or priors, has become increasingly accessible from multiple sources, yet its reliability may vary considerably. Existing approaches often integrate these priors without sufficiently accounting for their quality, which may…

多个实验的潜力：识别潜在结果的联合分布AI 解读

Typical causal effects are defined based on the marginal distribution of potential outcomes. However, many real-world applications require causal estimands involving the joint distribution of potential outcomes to enable more nuanced treatment evaluation and selection. In this article, we propose a novel framework for identifying and estimating the joint distribution of potential outcomes using multiple experimental datasets. We introduce the assumption of transportability…

弱重叠条件下的双重稳健估计量AI 解读

Doubly robust (DR) estimators guard against model misspecification but remain sensitive to weak covariate overlap. We show that trimming propensity scores reduces variance but eliminates double robustness. We introduce DR estimators that retain double robustness after trimming through bias correction, preserving the original causal targets across unconfoundedness, instrumental variables, and difference-in-differences designs. In four applications, the proposed estimator…

通过自适应借用外部对照改善试验中的处理效应估计AI 解读

Randomized controlled trials (RCTs) often suffer from limited inferential efficiency in estimating treatment effects due to their small sample sizes. In recent years, incorporating external controls (ECs) has gained increasing attention as an effective way to augment small RCTs and thereby enhance estimation efficiency. However, ECs are not always comparable to RCTs, and direct borrowing without careful evaluation can introduce substantial bias and, paradoxically, undermine…

重尾循环平稳时间序列的分数低阶协方差度量：依赖检验与模型阶数识别AI 解读

This article introduces new methods for the analysis of cyclostationary time series with infinite variance. Traditional cyclostationary analysis, based on periodically correlated (PC) processes, relies on the autocovariance function (ACVF). However, the ACVF is not suitable for data exhibiting a heavy-tailed distribution, particularly with infinite variance. Thus, we propose a novel framework for the analysis of cyclostationary time series with heavy-tailed distribution,…

多弱工具变量高维回归的多任务学习AI 解读

Many weak instrumental variables (IVs) are routinely used in the health and social sciences to improve identification and inference of the treatment effect of interest, along with a broad collection of data on potential confounding factors in the hope that the IV assumptions hold within each data stratum. We propose a new debiased continuous-updating generalized method of moments estimator with multi-task learning of the IV propensity scores to simultaneously address the…

根号 n 渐近正态的最大得分估计AI 解读

The maximum score method (Manski, 1975, 1985) is a powerful approach for binary choice models, yet it is known to face both practical and theoretical challenges. In particular, the estimator converges at a slower-than-root-$n$ rate to a nonstandard limiting distribution. We investigate conditions under which strictly concave surrogate score functions can be employed to achieve identification through a smooth criterion function. This criterion enables root-$n$ convergence to…

可解释 M 学习器框架下的生存分析异质性中介效应AI 解读

Mediation analysis is a useful tool to evaluate surrogate endpoints in clinical trials. We propose a novel method, the M-survival learner, for estimating heterogeneous indirect treatment effects in the presence of censored outcomes. The proposed approach enables the identification of interpretable patient subgroups characterized by distinct mediation pathways. To distinguish heterogeneous from homogeneous mediation effects, we introduce a new statistical criterion…