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Valid Instrumental Variables Selection Methods using Negative Control Outcomes and Constructing Efficient Estimator

利用负对照结局筛选有效工具变量并构造高效估计量

In observational studies, instrumental variable (IV) methods are commonly applied when there exists some unmeasured covariates. In Mendelian Randomization (MR), constructing an allele score by using many single nucleotide polymorphisms (SNPs) is often implemented; however, there are risks estimating biased causal effects by including some invalid IVs. Invalid IVs are candidates of IVs associated with some unobserved variables. To solve this problem, we propose a novel…

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Dynamic demand for differentiated products with fixed-effects unobserved heterogeneity

含固定效应不可观测异质性的差异化产品动态需求

This paper studies identification and estimation of a dynamic discrete choice model of demand for differentiated product using consumer-level panel data with few purchase events per consumer (i.e., short panel). Consumers are forward-looking and their preferences incorporate two sources of dynamics: last choice dependence due to habits and switching costs, and duration dependence due to inventory, depreciation, or learning. A key distinguishing feature of the model is that…

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Half-Trek Criterion for Identifiability of Latent Variable Models

潜变量模型可识别性的半路径准则

We consider linear structural equation models with latent variables and develop a criterion to certify whether the direct causal effects between the observable variables are identifiable based on the observed covariance matrix. Linear structural equation models assume that both observed and latent variables solve a linear equation system featuring stochastic noise terms. Each model corresponds to a directed graph whose edges represent the direct effects that appear as…

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Selecting Valid Instrumental Variables in Linear Models with Multiple Exposure Variables: Adaptive Lasso and the Median-of-Medians Estimator

多暴露线性模型中的有效工具变量选择:自适应 Lasso 与中位数的中位数估计量

In a linear instrumental variables (IV) setting for estimating the causal effects of multiple confounded exposure/treatment variables on an outcome, we investigate the adaptive Lasso method for selecting valid instrumental variables from a set of available instruments that may contain invalid ones. An instrument is invalid if it fails the exclusion conditions and enters the model as an explanatory variable. We extend the results as developed in Windmeijer et al. (2019) for…

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Endogeneity in Weakly Separable Models without Monotonicity

无需单调性的弱可分模型内生性处理

We identify and estimate treatment effects when potential outcomes are weakly separable with a binary endogenous treatment. Vytlacil and Yildiz (2007) proposed an identification strategy that exploits the mean of observed outcomes, but their approach requires a monotonicity condition. In comparison, we exploit full information in the entire outcome distribution, instead of just its mean. As a result, our method does not require monotonicity and is also applicable to general…

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Bias Formulas for Violations of Proximal Identification Assumptions

近端识别假设违反时的偏差公式

Causal inference from observational data often rests on the unverifiable assumption of no unmeasured confounding. Recently, Tchetgen Tchetgen and colleagues have introduced proximal inference to leverage negative control outcomes and exposures as proxies to adjust for bias from unmeasured confounding. However, some of the key assumptions that proximal inference relies on are themselves empirically untestable. Additionally, the impact of violations of proximal inference…

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Difference-in-Differences with a Misclassified Treatment

处理状态误分类下的双重差分

This paper studies identification and estimation of the average treatment effect on the treated (ATT) in difference-in-difference (DID) designs when the variable that classifies individuals into treatment and control groups (treatment status, D) is endogenously misclassified. We show that misclassification in D hampers consistent estimation of ATT because 1) it restricts us from identifying the truly treated from those misclassified as being treated and 2) differential…

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Weak Instruments, First-Stage Heteroskedasticity, the Robust F-Test and a GMM Estimator with the Weight Matrix Based on First-Stage Residuals

弱工具变量、第一阶段异方差、稳健 F 检验与基于第一阶段残差的 GMM

This paper is concerned with the findings related to the robust first-stage F-statistic in the Monte Carlo analysis of Andrews (2018), who found in a heteroskedastic grouped-data design that even for very large values of the robust F-statistic, the standard 2SLS confidence intervals had large coverage distortions. This finding appears to discredit the robust F-statistic as a test for underidentification. However, it is shown here that large values of the robust F-statistic…

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Proximal Causal Inference for Complex Longitudinal Studies

复杂纵向研究中的近端因果推断

A standard assumption for causal inference about the joint effects of time-varying treatment is that one has measured sufficient covariates to ensure that within covariate strata, subjects are exchangeable across observed treatment values, also known as "sequential randomization assumption (SRA)". SRA is often criticized as it requires one to accurately measure all confounders. Realistically, measured covariates can rarely capture all confounders with certainty. Often…

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Doubly Robust Proximal Causal Inference under Confounded Outcome-Dependent Sampling

混杂性结局依赖抽样下的双重稳健近端因果推断

Unmeasured confounding and selection bias are often of concern in observational studies and may invalidate a causal analysis if not appropriately accounted for. Under outcome-dependent sampling, a latent factor that has causal effects on the treatment, outcome, and sample selection process may cause both unmeasured confounding and selection bias, rendering standard causal parameters unidentifiable without additional assumptions. Under an odds ratio model for the treatment…

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Outcome Adaptive Propensity Score Methods for Handling Censoring and High-Dimensionality: Application to Insurance Claims

处理删失与高维变量的结局自适应倾向得分方法

Propensity scores are commonly used to reduce the confounding bias in non-randomized observational studies for estimating the average treatment effect. An important assumption underlying this approach is that all confounders that are associated with both the treatment and the outcome of interest are measured and included in the propensity score model. In the absence of strong prior knowledge about potential confounders, researchers may agnostically want to adjust for a…

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Identification and Inference with Min-over-max Estimators for the Measurement of Labor Market Fairness

劳动市场公平性度量中最小—最大估计量的识别与推断

These notes shows how to do inference on the Demographic Parity (DP) metric. Although the metric is a complex statistic involving min and max computations, we propose a smooth approximation of those functions and derive its asymptotic distribution. The limit of these approximations and their gradients converge to those of the true max and min functions, wherever they exist. More importantly, when the true max and min functions are not differentiable, the approximations still…

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Triangulating Instrumental Variable, confounder adjustment and Difference-in-Difference methods for comparative effectiveness research in observational data

观察性比较效果研究中的工具变量、混杂调整与双重差分三角验证

Observational studies can play a useful role in assessing the comparative effectiveness of competing treatments. In a clinical trial the randomization of participants to treatment and control groups generally results in well-balanced groups with respect to possible confounders, which makes the analysis straightforward. However, when analysing observational data, the potential for unmeasured confounding makes comparing treatment effects much more challenging. Causal inference…

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Bounding Counterfactuals under Selection Bias

选择偏差下反事实量的界限计算

Causal analysis may be affected by selection bias, which is defined as the systematic exclusion of data from a certain subpopulation. Previous work in this area focused on the derivation of identifiability conditions. We propose instead a first algorithm to address both identifiable and unidentifiable queries. We prove that, in spite of the missingness induced by the selection bias, the likelihood of the available data is unimodal. This enables us to use the causal…

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Alternative approaches for analysing repeated measures data that are missing not at random

非随机缺失重复测量数据的替代分析方法

We consider studies where multiple measures on an outcome variable are collected over time, but some subjects drop out before the end of follow up. Analyses of such data often proceed under either a 'last observation carried forward' or 'missing at random' assumption. We consider two alternative strategies for identification; the first is closely related to the difference-in-differences methodology in the causal inference literature. The second enables correction for…

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Partial Identification in Nonseparable Binary Response Models with Endogenous Regressors

含内生解释变量的非可分二元响应模型中的部分识别

This paper considers (partial) identification of a variety of counterfactual parameters in binary response models with possibly endogenous regressors. Our framework allows for nonseparable index functions with multi-dimensional latent variables, and does not require parametric distributional assumptions. We leverage results on hyperplane arrangements and cell enumeration from the literature on computational geometry in order to provide a tractable means of computing the…

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Doubly-Valid/Doubly-Sharp Sensitivity Analysis for Causal Inference with Unmeasured Confounding

未测混杂因果推断的双重有效与双重尖锐敏感性分析

We consider the problem of constructing bounds on the average treatment effect (ATE) when unmeasured confounders exist but have bounded influence. Specifically, we assume that omitted confounders could not change the odds of treatment for any unit by more than a fixed factor. We derive the sharp partial identification bounds implied by this assumption by leveraging distributionally robust optimization, and we propose estimators of these bounds with several novel robustness…

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Testing for a Threshold in Models with Endogenous Regressors

含内生解释变量模型中的阈值检验

We show by simulation that the test for an unknown threshold in models with endogenous regressors - proposed in Caner and Hansen (2004) - can exhibit severe size distortions both in small and in moderately large samples, pertinent to empirical applications. We propose three new tests that rectify these size distortions. The first test is based on GMM estimators. The other two are based on unconventional 2SLS estimators, that use additional information about the linearity (or…

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Treatment Effect Risk: Bounds and Inference

处理效应风险:界限与推断

Since the average treatment effect (ATE) measures the change in social welfare, even if positive, there is a risk of negative effect on, say, some 10% of the population. Assessing such risk is difficult, however, because any one individual treatment effect (ITE) is never observed, so the 10% worst-affected cannot be identified, while distributional treatment effects only compare the first deciles within each treatment group, which does not correspond to any…

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The role of the geometric mean in case-control studies

几何平均在病例对照研究中的作用

Historically used in settings where the outcome is rare or data collection is expensive, outcome-dependent sampling is relevant to many modern settings where data is readily available for a biased sample of the target population, such as public administrative data. Under outcome-dependent sampling, common effect measures such as the average risk difference and the average risk ratio are not identified, but the conditional odds ratio is. Aggregation of the conditional odds…

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Nonlinear and Nonseparable Structural Functions in Fuzzy Regression Discontinuity Designs

模糊断点回归中的非线性与非可分结构函数

Many empirical examples of regression discontinuity (RD) designs concern a continuous treatment variable, but the theoretical aspects of such models are less studied. This study examines the identification and estimation of the structural function in fuzzy RD designs with a continuous treatment variable. The structural function fully describes the causal impact of the treatment on the outcome. We show that the nonlinear and nonseparable structural function can be…

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Multiscale Causal Structure Learning

多尺度因果结构学习

The inference of causal structures from observed data plays a key role in unveiling the underlying dynamics of the system. This paper exposes a novel method, named Multiscale-Causal Structure Learning (MS-CASTLE), to estimate the structure of linear causal relationships occurring at different time scales. Differently from existing approaches, MS-CASTLE takes explicitly into account instantaneous and lagged inter-relations between multiple time series, represented at…

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Two-stage differences in differences

两阶段双重差分

A recent literature has shown that when adoption of a treatment is staggered and average treatment effects vary across groups and over time, difference-in-differences regression does not identify an easily interpretable measure of the typical effect of the treatment. In this paper, I extend this literature in two ways. First, I provide some simple underlying intuition for why difference-in-differences regression does not identify a group$\times$period average treatment…

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Positivity: Identifiability and Estimability

正值性:可识别性与可估计性

Positivity, the assumption that every unique combination of confounding variables that occurs in a population has a non-zero probability of an action, can be further delineated as deterministic positivity and stochastic positivity. Here, we revisit this distinction, examine its relation to nonparametric identifiability and estimability, and discuss how to address violations of positivity assumptions. Finally, we relate positivity to recent interest in machine learning, as…

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