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FLAT: Fused Lasso Regression with Adaptive Minimum Spanning Tree with Applications on Thermohaline Circulation

融合自适应最小生成树的Fused Lasso回归及其在热盐环流中的应用

This article introduces a new methodology model both discrete and continuous spatial heterogeneity simultaneously with an application in detection of hyper-plain in thermohaline circulation. To enable the data-driven detection of spatial boundaries with heterogeneity, we constructs an adaptive minimum spanning tree guided by both spatial proximity and coefficient dissimilarity, and combines both a spatial fused regularization and LASSO-type regularization to estimate the…

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Randomized Quasi-Monte Carlo Features for Kernel Approximation

随机拟蒙特卡洛特征用于核近似

We investigate the application of randomized quasi-Monte Carlo (RQMC) methods in random feature approximations for kernel-based learning. Compared to the classical Monte Carlo (MC) approach \citep{rahimi2007random}, RQMC improves the deterministic approximation error bound from $O_P(1/\sqrt{M})$ to $O(1/M)$ (up to logarithmic factors), matching the rate achieved by quasi-Monte Carlo (QMC) methods \citep{huangquasi}. Beyond the deterministic error bound guarantee, we further…

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Predicting Market Troughs: A Machine Learning Approach with Causal Interpretation

市场低谷预测:具有因果解释的机器学习方法

This paper provides robust, new evidence on the causal drivers of market troughs. We demonstrate that conclusions about these triggers are critically sensitive to model specification, moving beyond restrictive linear models with a flexible DML average partial effect causal machine learning framework. Our robust estimates identify the volatility of options-implied risk appetite and market liquidity as key causal drivers, relationships misrepresented or obscured by simpler…

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WISE: A Weighted Similarity Aggregation Test for Serial Independence

WISE:基于加权相似度汇总的序列独立性检验

We propose a nonparametric test for serial independence that aggregates pairwise similarities of observations with lag-dependent weights. The resulting statistic is powerful to general forms of temporal dependence, including nonlinear and uncorrelated alternatives, and applies to ultra-high-dimensional and non-Euclidean data. We derive asymptotic normality under both permutation and population nulls, and establish consistency in classical large-sample and…

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Inferring Change Points in High-Dimensional Regression via Approximate Message Passing

高维回归中变点的近似消息传递推断

We consider the problem of localizing change points in a generalized linear model (GLM), a model that covers many widely studied problems in statistical learning including linear, logistic, and rectified linear regression. We propose a novel and computationally efficient Approximate Message Passing (AMP) algorithm for estimating both the signals and the change point locations, and rigorously characterize its performance in the high-dimensional limit where the number of…

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A Latent Class Bayesian Model for Multivariate Longitudinal Outcomes with Excess Zeros

含超额零值的多变量纵向结果的潜类别贝叶斯模型

Latent class models have been successfully used to handle complex datasets in different disciplines. For longitudinal outcomes, we often get a trajectory of the outcome for each individual, and on that basis, we cluster them for a powerful statistical inference. Latent class models have been used to handle multivariate longitudinal outcomes coming from biology, health sciences, and economics. In this paper, we propose a Bayesian latent class model for multivariate outcomes…

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Applying non-negative matrix factorization with covariates to multivariate time series data as a vector autoregression model

将含协变量的非负矩阵分解与向量自回归结合分析多变量时间序列

We propose a novel framework for analyzing multivariate time series (MTS) data by integrating non-negative matrix factorization (NMF) with vector autoregression (VAR). Termed NMF-VAR, this method models the coefficient matrix of NMF as a VAR process, enabling simultaneous extraction of latent components and temporal dependencies. Unlike standard VAR, which struggles with high dimensionality and lacks clarity, our method introduces a low-rank latent structure that reduces the…

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Precision Mental Health: Predicting Heterogeneous Treatment Effects for Depression through Data Integration

精准精神健康:通过数据整合预测抑郁症的异质性处理效应

When treating depression, clinicians are interested in determining the optimal treatment for a given patient, which is challenging given the amount of treatments available. To advance individualized treatment allocation, integrating data across multiple randomized controlled trials (RCTs) can enhance our understanding of treatment effect heterogeneity by increasing available information. However, extending these inferences to individuals outside of the original RCTs remains…

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An Interpretable Ensemble Framework for Multi-Omics Dementia Biomarker Discovery Under HDLSS Conditions

HDLSS条件下多组学痴呆生物标志物发现的可解释集成框架

Biomarker discovery in neurodegenerative diseases requires robust, interpretable frameworks capable of integrating high-dimensional multi-omics data under low-sample conditions. We propose a novel ensemble approach combining Graph Attention Networks (GAT), MultiOmics Variational AutoEncoder (MOVE), Elastic-net sparse regression, and Storey's False Discovery Rate (FDR). This framework is benchmarked against state-of-the-art methods including DIABLO, MOCAT, AMOGEL, and MOMLIN.…

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Estimation of High-Dimensional Markov-Switching VAR Models with an Approximate EM Algorithm

利用近似EM算法估计高维马尔可夫切换VAR模型

Regime shifts in high-dimensional time series arise naturally in many applications, from neuroimaging to finance. This problem has received considerable attention in low-dimensional settings, with both Bayesian and frequentist methods used extensively for parameter estimation. The EM algorithm is a particularly popular strategy for parameter estimation in low-dimensional settings, although the statistical properties of the resulting estimates have not been well understood.…

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An integrated method for clustering and association network inference

聚类与关联网络推断的整合方法

High dimensional Gaussian graphical models provide a rigorous framework to describe a network of statistical dependencies between entities, such as genes in genomic regulation studies or species in ecology. Penalized methods, including the standard Graphical-Lasso, are well-known approaches to infer the parameters of these models. As the number of variables in the model (of entities in the network) grow, the network inference and interpretation become more complex. The…

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Bayesian Network Propensity Score to Evaluate Treatment Effects in Observational Studies

用于观察性研究处理效应评估的贝叶斯网络倾向得分

This paper focuses on the Bayesian Network Propensity Score (BNPS), a novel approach for estimating treatment effects in observational studies characterized by unknown (and likely unbalanced) designs and complex dependency structures among covariates. Traditional methods, such as logistic regression, often impose rigid parametric assumptions that may lead to misspecification errors, compromising causal inference. Recent classical and machine learning alternatives, such as…

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Learning sparse generalized linear models with binary outcomes via iterative hard thresholding

基于迭代硬阈值的学习二元结果稀疏广义线性模型

In statistics, generalized linear models (GLMs) are widely used for modeling data and can expressively capture potential nonlinear dependence of the model's outcomes on its covariates. Within the broad family of GLMs, those with binary outcomes, which include logistic and probit regressions, are motivated by common tasks such as binary classification with (possibly) non-separable data. In addition, in modern machine learning and statistics, data is often high-dimensional yet…

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Statistical Inference for Heterogeneous Treatment Effect with Right-censored Data from Synthesizing Randomized Clinical Trials and Real-world Data

融合随机试验与真实世界右删失数据的异质处理效应推断

The heterogeneous treatment effect plays a crucial role in precision medicine.There is evidence that real-world data, even subject to biases, can be employed as supplementary evidence for randomized clinical trials to improve the statistical efficiency of the heterogeneous treatment effect estimation. In this paper, for survival data with right censoring, we consider estimating the heterogeneous treatment effect, defined as the difference of the treatment-specific…

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Causal Spatial Quantile Regression

因果空间分位数回归

Treatment effects in a wide range of economic, environmental, and epidemiological applications often vary across space, and understanding the heterogeneity of causal effects across space and outcome quantiles is a critical challenge in spatial causal inference. To effectively capture spatial heterogeneity in distributional treatment effects, we propose a novel semiparametric neural network-based causal framework leveraging deep spatial quantile regression and then construct…

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Bayesian Estimation and Regularization Techniques in Categorical Data Analysis

分类数据分析中的贝叶斯估计与正则化方法

This paper explores Bayesian estimation for categorical data, focusing on simple yet effective models that provide a foundation for applying more advanced methods accurately and reliably in real-world applications. We begin by revisiting Bayesian estimators for the binomial distribution and investigating their properties. Next, we develop hypothesis tests for categorical data (sign test, homogeneity test, symmetry test) based on regularized maximum likelihood estimates of…

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Semi-supervised linear regression: enhancing efficiency and robustness in high dimensions

半监督线性回归:高维下提升效率与稳健性

In semi-supervised learning, the prevailing understanding suggests that observing additional unlabeled samples improves estimation accuracy for linear parameters only in the case of model misspecification. In this work, we challenge such a claim and show that additional unlabeled samples are beneficial in high-dimensional settings. Initially focusing on a dense scenario, we introduce robust semi-supervised estimators for the regression coefficient without relying on sparse…

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Uncertainty Quantification for Ranking with Heterogeneous Preferences

异质偏好排序的不确定性量化

This paper studies human preference learning based on partially revealed choice behavior and formulates the problem as a generalized Bradley-Terry-Luce (BTL) ranking model that accounts for heterogeneous preferences. Specifically, we assume that each user is associated with a nonparametric preference function, and each item is characterized by a low-dimensional latent feature vector - their interaction defines the underlying low-rank score matrix. In this formulation, we…

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On the Estimation of Multinomial Logit and Nested Logit Models: A Conic Optimization Approach

多项 Logit 与嵌套 Logit 估计的锥优化方法

In this paper, we revisit parameter estimation for multinomial logit (MNL), nested logit (NL), and tree-nested logit (TNL) models through the framework of convex conic optimization. Traditional approaches typically solve the maximum likelihood estimation (MLE) problem using gradient-based methods, which are sensitive to step-size selection and initialization, and may therefore suffer from slow or unstable convergence. In contrast, we propose a novel estimation strategy that…

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Cardinality Sparsity: Applications in Matrix-Matrix Multiplications and Machine Learning

基数稀疏性:在矩阵乘法与机器学习中的应用

High-dimensional data has become ubiquitous across the sciences but presents computational and statistical challenges. A common approach to addressing these challenges is through sparsity. In this paper, we introduce a new concept of sparsity, called cardinality sparsity. Broadly speaking, we define a tensor as sparse if it contains only a small number of unique values. We demonstrate that cardinality sparsity can improve deep learning and tensor regression both…

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Causal SHAP: Feature Attribution with Dependency Awareness through Causal Discovery

因果 SHAP:通过因果发现实现依赖关系感知的特征归因

Explaining machine learning (ML) predictions has become crucial as ML models are increasingly deployed in high-stakes domains such as healthcare. While SHapley Additive exPlanations (SHAP) is widely used for model interpretability, it fails to differentiate between causality and correlation, often misattributing feature importance when features are highly correlated. We propose Causal SHAP, a novel framework that integrates causal relationships into feature attribution while…

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ProCause: Generating Counterfactual Outcomes to Evaluate Prescriptive Process Monitoring Methods

ProCause:生成反事实结果以评估处方式流程监控方法

Prescriptive Process Monitoring (PresPM) is the subfield of Process Mining that focuses on optimizing processes through real-time interventions based on event log data. Evaluating PresPM methods is challenging due to the lack of ground-truth outcomes for all intervention actions in datasets. A generative deep learning approach from the field of Causal Inference (CI), RealCause, has been commonly used to estimate the outcomes for proposed intervention actions to evaluate a…

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Statistical Performance Guarantee for Subgroup Identification with Generic Machine Learning

通用机器学习子群识别的统计性能保证

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

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Semiparametric model averaging for high-dimensional quantile regression with nonignorable nonresponse

不可忽略缺失下高维分位数回归的半参数模型平均

Model averaging has demonstrated superior performance for ensemble forecasting in high-dimensional framework, its extension to incomplete datasets remains a critical but underexplored challenge. Moreover, identifying the parsimonious model through averaging procedure in quantile regression demands urgent methodological innovation. In this paper, we propose a novel model averaging method for high-dimensional quantile regression with nonignorable missingness. The idea is to…

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