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Incorporating External Controls for Estimating the Average Treatment Effect on the Treated with High-Dimensional Data: Retaining Double Robustness and Ensuring Double Safety

高维数据下利用外部对照估计 ATT:保留双重稳健性并确保双重安全性

Randomized controlled trials (RCTs) are widely regarded as the gold standard for causal inference in biomedical research. For instance, when estimating the average treatment effect on the treated (ATT), a doubly robust estimation procedure can be applied, requiring either the propensity score model or the control outcome model to be correctly specified. In this paper, we address scenarios where external control data, often with a much larger sample size, are available. Such…

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Factor and Idiosyncratic VAR Volatility Matrix Models for Heavy-Tailed High-Frequency Financial Observations

重尾高频金融观测下的因子与特质 VAR 波动率矩阵模型

This paper introduces a novel process for both factor and idiosyncratic volatility matrices whose eigenvalues follow the vector auto-regressive (VAR) model. We call it the factor and idiosyncratic VAR (FIVAR) model. The FIVAR model accounts for the dynamics of the factor and idiosyncratic volatilities and includes many parameters. In addition, many empirical studies have shown that high-frequency stock returns and volatilities often exhibit heavy tails. To handle these two…

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Matrix Autoregressive Model with Vector Time Series Covariates for Spatio-Temporal Data

含向量时间序列协变量的时空矩阵自回归模型

We develop a new methodology for forecasting matrix-valued time series with historical matrix data and auxiliary vector time series data. We focus on a time series of matrices defined on a static 2-D spatial grid and an auxiliary time series of non-spatial vectors. The proposed model, Matrix AutoRegression with Auxiliary Covariates (MARAC), contains an autoregressive component for the historical matrix predictors and an additive component that maps the auxiliary vector…

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Robust High-Dimensional Time-Varying Coefficient Estimation

稳健的高维时变系数估计

In this paper, we develop a novel high-dimensional coefficient estimation procedure based on high-frequency data. Unlike usual high-dimensional regression procedures such as LASSO, we additionally handle the heavy-tailedness of high-frequency observations as well as time variations of coefficient processes. Specifically, we employ the Huber loss and a truncation scheme to handle heavy-tailed observations, while $\ell_{1}$-regularization is adopted to overcome the curse of…

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Causal Machine Learning for Surgical Interventions

外科干预的因果机器学习

Surgical decision-making is complex and requires understanding causal relationships between patient characteristics, interventions, and outcomes. In high-stakes settings like spinal fusion or scoliosis correction, accurate estimation of individualized treatment effects (ITEs) remains limited due to the reliance on traditional statistical methods that struggle with complex, heterogeneous data. In this study, we develop a multi-task meta-learning framework, X-MultiTask, for…

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Forecasting High Dimensional Time Series with Dynamic Dimension Reduction

利用动态降维预测高维时间序列

Many dimension reduction techniques have been developed for independent data, and most have also been extended to time series. However, these methods often fail to account for the dynamic dependencies both within and across series. In this work, we propose a general framework for forecasting high-dimensional time series that integrates dynamic dimension reduction with regularization techniques. The effectiveness of the proposed approach is illustrated through a simulated…

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Enhanced Survival Trees

增强生存树

We introduce a new survival tree method for censored failure time data that incorporates three key advancements over traditional approaches. First, we develop a more computationally efficient splitting procedure that effectively mitigates the end-cut preference problem, and we propose an intersected validation strategy to reduce the variable selection bias inherent in greedy searches. Second, we present a novel framework for determining tree structures through fused…

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Bayesian Multivariate Density-Density Regression

贝叶斯多元密度-密度回归

We introduce a novel and scalable Bayesian framework for multivariate-density-density regression (DDR), designed to model relationships between multivariate distributions. Our approach addresses the critical issue of distributions residing in spaces of differing dimensions. We utilize a generalized Bayes framework, circumventing the need for a fully specified likelihood by employing the sliced Wasserstein distance to measure the discrepancy between fitted and observed…

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Power-Dominance in Estimation Theory: A Third Pathological Axis

估计理论中的功效主导:第三条病态轴

This paper introduces a novel framework for estimation theory by introducing a second-order diagnostic for estimator design. While classical analysis focuses on the bias-variance trade-off, we present a more foundational constraint. This result is model-agnostic, domain-agnostic, and is valid for both parametric and non-parametric problems, Bayesian and frequentist frameworks. We propose to classify the estimators into three primary power regimes. We theoretically establish…

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Posterior contraction rates in a sparse non-linear mixed-effects model

稀疏非线性混合效应模型中的后验收缩率

Recent works have shown an interest in investigating the frequentist asymptotic properties of Bayesian procedures for high-dimensional linear models under sparsity constraints. However, there exists a gap in the literature regarding analogous theoretical findings for non-linear models within the high-dimensional setting. The current study provides a novel contribution, focusing specifically on a non-linear mixed-effects model. In this model, the residual variance is assumed…

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Learning Massive-scale Partial Correlation Networks in Clinical Multi-omics Studies with HP-ACCORD

HP-ACCORD:临床多组学研究中的大规模偏相关网络学习

Graphical model estimation from multi-omics data requires a balance between statistical estimation performance and computational scalability. We introduce a novel pseudolikelihood-based graphical model framework that reparameterizes the target precision matrix while preserving the sparsity pattern and estimates it by minimizing an $\ell_1$-penalized empirical risk based on a new loss function. The proposed estimator maintains estimation and selection consistency in various…

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Kernel Ridge Regression with Predicted Feature Inputs and Applications to Factor-Based Nonparametric Regression

带预测特征输入的核岭回归及其在因子型非参数回归中的应用

Kernel methods, particularly kernel ridge regression (KRR), are time-proven, powerful nonparametric regression techniques known for their rich capacity, analytical simplicity, and computational tractability. The analysis of their predictive performance has received continuous attention for more than two decades. However, in many modern regression problems where the feature inputs used in KRR cannot be directly observed and must instead be inferred from other measurements,…

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Automatic Debiased Machine Learning for Covariate Shifts

协变量分布偏移下的自动去偏机器学习

We present machine learning estimators for causal and predictive parameters under covariate shift, where covariate distributions differ between training and target populations. One such parameter is the average effect of a policy that alters the covariate distribution, such as a treatment modifying surrogate covariates used to predict long-term outcomes. Another example is the average treatment effect for a population with a shifted covariate distribution, like the effect of…

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Large Scale Partial Correlation Screening with Uncertainty Quantification

大规模偏相关筛选与不确定性量化

Identifying multivariate dependencies in high-dimensional data is an important problem in large-scale inference. This problem has motivated recent advances in mining (partial) correlations, which focus on the challenging ultra-high dimensional setting where the sample size, n, is fixed, while the number of features, p, grows without bound. The state-of-the-art method for partial correlation screening can lead to undesirable results. This paper introduces a novel principled…

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Rate doubly robust estimation for weighted average treatment effects

加权平均处理效应的速率双重稳健估计

The weighted average treatment effect (WATE) defines a versatile class of causal estimands for populations characterized by propensity score weights, including the average treatment effect (ATE), treatment effect on the treated (ATT), on controls (ATC), and for the overlap population (ATO). WATE has broad applicability in social and medical research, as many datasets from these fields align with its framework. However, the literature lacks a systematic investigation into the…

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Mixing properties of some Markov chains models in random environments

若干随机环境马尔可夫链模型的混合性质

Markov chains in random environments (MCREs) have recently attracted renewed interest, as these processes naturally arise in many applications, such as econometrics and machine learning. Although specific asymptotic results, such as the law of the large numbers and central limit theorems, have been obtained for some of these models, their annealed dependence properties, such as strong mixing properties, are not well understood in general. We derive strong mixing properties…

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What is a good matching of probability measures? A counterfactual lens on transport maps

什么是概率测度的良好匹配?传输映射的反事实视角

Coupling probability measures lies at the core of many problems in statistics and machine learning, from domain adaptation to transfer learning and causal inference. Yet, even when restricted to deterministic transports, such couplings are not identifiable: two atomless marginals admit infinitely many transport maps. The common recourse to optimal transport, motivated by cost minimization and cyclical monotonicity, obscures the fact that several distinct notions of…

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Semiparametric principal stratification analysis beyond monotonicity

超越单调性假设的半参数主分层分析

Intercurrent events, common in clinical trials and observational studies, affect the existence or interpretation of final outcomes. Principal stratification addresses this challenge by defining local average treatment effect estimands within subpopulations, but often relies on restrictive assumptions such as monotonicity and counterfactual intermediate independence. To overcome these limitations, we propose a semiparametric framework for principal stratification analysis…

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Joint Learning of Panel VAR models with Low Rank and Sparse Structure

具有低秩与稀疏结构的面板 VAR 联合学习

Panel vector auto-regressive (VAR) models are widely used to capture the dynamics of multivariate time series across different subpopulations, where each subpopulation shares a common set of variables. In this work, we propose a panel VAR model with a shared low-rank structure, modulated by subpopulation-specific weights, and complemented by idiosyncratic sparse components. To ensure parameter identifiability, we impose structural constraints that lead to a nonsmooth,…

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Probabilistic and nonlinear compressive sensing

概率性与非线性压缩感知

We present a smooth probabilistic reformulation of $\ell_0$ regularized regression that does not require Monte Carlo sampling and allows for the computation of exact gradients, facilitating rapid convergence to local optima of the best subset selection problem. The method drastically improves convergence speed compared to similar Monte Carlo based approaches. Furthermore, we empirically demonstrate that it outperforms compressive sensing algorithms such as IHT and (Relaxed-)…

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Modelling peaks over thresholds in panel data: a two-level grouped panel generalized Pareto regression

面板数据的超阈值峰值建模:两层分组广义帕累托回归

Panel data arise in a wide range of application areas, and developing modelling methods for extreme values under such a setup is essential for reliable risk assessment and management. When choosing to model the marginal distributions of univariate extremes, one may wish to balance the flexibility in capturing the heterogeneity among margins and the efficiency of estimation. This can be achieved through a combination of regression techniques and assuming a latent group…

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Alternative Likelihood Approximations for High-Dimensional Intervals for Lasso

高维 Lasso 区间估计的替代似然近似

Classical frequentist approaches to inference for the lasso emphasize exact coverage for each feature, which requires debiasing and severs the connection between confidence intervals and the original lasso estimates. To address this, in earlier work we introduced the idea of average coverage, allowing for biased intervals that align with the lasso point estimates, and proposed the Relaxed Lasso Posterior (RL-P) intervals, which leverage the Bayesian interpretation of the…

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Forecasting in small open emerging economies Evidence from Thailand

小型开放新兴经济体的预测:来自泰国的证据

Forecasting inflation in small open economies is difficult because limited time series and strong external exposures create an imbalance between few observations and many potential predictors. We study this challenge using Thailand as a representative case, combining more than 450 domestic and international indicators. We evaluate modern Bayesian shrinkage and factor models, including Horseshoe regressions, factor-augmented autoregressions, factor-augmented VARs, dynamic…

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High-dimensional Statistical Inference and Variable Selection Using Sufficient Dimension Association

高维统计推断与充分降维关联下的变量选择

Simultaneous variable selection and statistical inference is challenging in high-dimensional data analysis. Most existing post-selection inference methods require explicitly specified regression models, which are often linear, as well as sparsity in the regression model. The performance of such procedures can be poor under either misspecified nonlinear models or a violation of the sparsity assumption. In this paper, we propose a sufficient dimension association (SDA)…

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