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Censored Graphical Horseshoe: Bayesian sparse precision matrix estimation with censored and missing data

删失图马蹄先验:含删失与缺失数据的贝叶斯稀疏精度矩阵估计

Gaussian graphical models provide a powerful framework for studying conditional dependencies in multivariate data, with widespread applications spanning biomedical, environmental sciences, and other data-rich scientific domains. While the Graphical Horseshoe (GHS) method has emerged as a state-of-the-art Bayesian method for sparse precision matrix estimation, existing approaches assume fully observed data and thus fail in the presence of censoring or missingness, which are…

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A Symmetric Random Scan Collapsed Gibbs Sampler for Fully Bayesian Variable Selection with Spike-and-Slab Priors

对称随机扫描坍缩 Gibbs 抽样器:尖峰-平板先验下的全贝叶斯变量选择

We introduce a symmetric random scan Gibbs sampler for scalable Bayesian variable selection that eliminates storage of the full cross-product matrix by computing required quantities on-the-fly. Data-informed proposal weights, constructed from marginal correlations, concentrate sampling effort on promising candidates while a uniform mixing component ensures theoretical validity. We provide explicit guidance for selecting tuning parameters based on the ratio of signal to null…

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Long-Term Causal Inference with Many Noisy Proxies

利用大量含噪代理变量进行长期因果推断

We propose a method for estimating long-term treatment effects with many short-term proxy outcomes: a central challenge when experimenting on digital platforms. We formalize this challenge as a latent variable problem where observed proxies are noisy measures of a low-dimensional set of unobserved surrogates that mediate treatment effects. Through theoretical analysis and simulations, we demonstrate that regularized regression methods substantially outperform naive proxy…

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Expectile Periodograms

期望分位数周期图

This paper introduces a novel periodogram-like function, called the expectile periodogram, for modeling spectral features of time series and detecting hidden periodicities. The expectile periodogram is constructed from trigonometric expectile regression, in which a specially designed check function is used to substitute the squared $l_2$ norm that leads to the ordinary periodogram. The expectile periodogram retains the key properties of the ordinary periodogram as a…

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Estimating optimal interpretable individualized treatment regimes from a classification perspective using adaptive LASSO

从分类视角利用自适应 LASSO 估计可解释的最优个体化治疗规则

Real-world data (RWD) gains growing interests to provide a representative sample of the population for selecting the optimal treatment options. However, existing complex black box methods for estimating individualized treatment rules (ITR) from RWD have problems in interpretability and convergence. Providing an interpretable and sparse ITR can be used to overcome the limitation of existing methods. We developed an algorithm using Adaptive LASSO to predict optimal…

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A latent factor approach to hyperspectral time series data for multivariate genomic prediction of grain yield in wheat

利用高光谱时间序列潜在因子进行小麦产量的多变量基因组预测

High-dimensional time series phenotypic data is becoming increasingly common within plant breeding programmes. However, analysing and integrating such data for genetic analysis and genomic prediction remains difficult. Here we show how factor analysis with Procrustes rotation on the genetic correlation matrix of hyperspectral secondary phenotype data can help in extracting relevant features for within-trial prediction. We use a subset of Centro Internacional de Mejoramiento…

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Scalability of Metropolis-within-Gibbs schemes for high-dimensional Bayesian models

We study general coordinate-wise MCMC schemes (such as Metropolis-within-Gibbs samplers), which are commonly used to fit Bayesian non-conjugate hierarchical models. We relate their convergence properties to the ones of the corresponding (potentially not implementable) Gibbs sampler through the notion of conditional conductance. This allows us to study the performances of popular Metropolis-within-Gibbs schemes for non-conjugate hierarchical models, in high-dimensional…

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Learning and Testing Exposure Mappings of Interference using Graph Convolutional Autoencoder

利用图卷积自编码器学习并检验干扰的暴露映射

Interference or spillover effects arise when an individual's outcome (e.g., health) is influenced not only by their own treatment (e.g., vaccination) but also by the treatment of others, creating challenges for evaluating treatment effects. Exposure mappings provide a framework to study such interference by explicitly modeling how the treatment statuses of contacts within an individual's network affect their outcome. Most existing research relies on a priori exposure…

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The Curious Case of Aid and Conflict: Causal Evidence from Panel Econometrics and Composite Indices

援助与冲突的复杂关系:面板计量与综合指数的证据

This paper examines the relationship between Official Development Assistance (ODA) and conflict in the ten largest aid-receiving African countries between 2009 and 2023. Using Ordinary Least Squares, Principal Component Analysis, and Ridge (L2) regression, the study assesses whether conflict, proxied by political stability, governance indicators, and macroeconomic conditions, systematically influences aid inflows. Results reveal a nuanced relationship. Pooled regressions…

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What Functions Does XGBoost Learn?

XGBoost 学习的是什么函数?

This paper establishes a rigorous theoretical foundation for the function class implicitly learned by XGBoost, bridging the gap between its empirical success and our theoretical understanding. We introduce an infinite-dimensional function class $\mathcal{F}^{d, s}_{\infty-\text{ST}}$ that extends finite ensembles of bounded-depth regression trees, together with a complexity measure $V^{d, s}_{\infty-\text{XGB}}(\cdot)$ that generalizes the $L^1$ regularization penalty used…

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Multi-Group Quadratic Discriminant Analysis via Projection

Multi-group classification arises in many prediction and decision-making problems, including applications in epidemiology, genomics, finance, and image recognition. Although classification methods have advanced considerably, much of the literature focuses on binary problems, and available extensions often provide limited flexibility for multi-group settings. Recent work has extended linear discriminant analysis to multiple groups, but more general methods are still needed to…

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Stochastic Deep Learning: A Probabilistic Framework for Modeling Uncertainty in Structured Temporal Data

随机深度学习:结构化时间数据不确定性建模的概率框架

I propose a novel framework that integrates stochastic differential equations (SDEs) with deep generative models to improve uncertainty quantification in machine learning applications involving structured and temporal data. This approach, termed Stochastic Latent Differential Inference (SLDI), embeds an Itô SDE in the latent space of a variational autoencoder, allowing for flexible, continuous-time modeling of uncertainty while preserving a principled mathematical…

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Avoiding the Price of Adaptivity: Inference in Linear Contextual Bandits via Stability

避免适应性的代价:基于稳定性的线性情境赌博机推断

Statistical inference in contextual bandits is challenging due to the adaptive, non-i.i.d. nature of the data. A growing body of work shows that classical least-squares inference can fail under adaptive sampling, and that valid confidence intervals for linear functionals typically require an inflation of order $\sqrt{d \log T}$. This phenomenon -- often termed the price of adaptivity -- reflects the intrinsic difficulty of reliable inference under general contextual bandit…

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Uncovering Treatment Effect Heterogeneity in Pragmatic Gerontology Trials

揭示实用性老年医学试验中的处理效应异质性

Detecting heterogeneity in treatment response enriches the interpretation of gerontologic trials. In aging research, estimating the effect of the intervention on clinically meaningful outcomes faces analytical challenges when it is truncated by death. For example, in the Whole Systems Demonstrator trial, a large cluster-randomized study evaluating telecare among older adults, the overall effect of the intervention on quality of life was found to be null. However, this…

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Ridge Estimation of High Dimensional Two-Way Fixed Effect Regression

高维双向固定效应回归的岭估计

We study a ridge estimator for the high-dimensional two-way fixed effect regression model with a sparse bipartite network. We develop concentration inequalities showing that when the ridge parameters increase as the log of the network size, the bias, and the variance-covariance matrix of the vector of estimated fixed effects converge to deterministic equivalents that depend only on the expected network. We provide simulations and an application using administrative data on…

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High-Dimensional Precision Matrix Quadratic Forms: Estimation Framework for $p > n$

We propose a novel estimation framework for quadratic functionals of precision matrices in high-dimensional settings, particularly in regimes where the feature dimension $p$ exceeds the sample size $n$. Traditional moment-based estimators with bias correction remain consistent when $p n$, highlighting a fundamental distinction between the two regimes due to rank deficiency and high-dimensional complexity. Our approach resolves these issues by combining a spectral-moment…

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Ill-Conditioned Orthogonal Scores in Double Machine Learning

双重机器学习中病态正交得分的误差放大

Double Machine Learning is often justified by nuisance-rate conditions, yet finite-sample reliability also depends on the conditioning of the orthogonal-score Jacobian. This conditioning is typically assumed rather than tracked. When residualized treatment variance is small, the Jacobian is ill-conditioned and small systematic nuisance errors can be amplified, so nominal confidence intervals may look precise yet systematically under-cover. Our main result is an exact…

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Diaconis-Ylvisaker prior penalized likelihood for $p/n \to κ\in (0,1)$ logistic regression

We characterise the behavior of the maximum Diaconis--Ylvisaker prior penalized likelihood estimator in high-dimensional logistic regression, where the number of covariates is a fraction $κ\in (0,1)$ of the number of observations $n$, as $n \to \infty$. We construct a rescaled estimator with zero asymptotic aggregate bias and define adjusted $Z$-statistics and rescaled penalized likelihood ratio statistics that exhibit the typical null asymptotic distributions, when the…

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Source-Optimal Training is Transfer-Suboptimal

源任务最优训练在迁移上并非最优

We prove that training a source model optimally for its own task is generically suboptimal when the objective is downstream transfer. We study the source-side optimization problem in L2-SP ridge regression and show a fundamental mismatch between the source-optimal and transfer-optimal source regularization: outside of a measure-zero set, $τ_0^* \neq τ_S^*$. We characterize the transfer-optimal source penalty $τ_0^*$ as a function of task alignment and identify an…

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Scalable Ultra-High-Dimensional Quantile Regression with Genomic Applications

Modern datasets arising from social media, genomics, and biomedical informatics are often heterogeneous and (ultra) high-dimensional, creating substantial challenges for conventional modeling techniques. Quantile regression (QR) not only offers a flexible way to capture heterogeneous effects across the conditional distribution of an outcome, but also naturally produces prediction intervals that help quantify uncertainty in future predictions. However, classical QR methods…

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Improve Power of Knockoffs with Annotation Information of Covariates

利用协变量注释信息提高 Knockoff 变量选择的功效

Genome-wide association studies (GWAS) often find association signals between many genetic variants and traits of interest in a genomic region. Functional annotations of these variants provide valuable prior information that helps prioritize biologically relevant variants and enhances the power to detect causal variants. However, due to substantial correlations among these variants, a critical question is how to rigorously control the false discovery rate while effectively…

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Group lasso based selection for high-dimensional mediation analysis

基于组 Lasso 选择的高维中介分析

Mediation analysis aims to identify and estimate the effect of an exposure on an outcome that is mediated through one or more intermediate variables. In the presence of multiple intermediate variables, two pertinent methodological questions arise: estimating mediated effects when mediators are correlated, and performing high-dimensional mediation analyses when the number of mediators exceeds the sample size. This paper presents a two-step procedure for high-dimensional…

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Asymptotic Inference for Constrained Regression

We consider statistical inference in high-dimensional regression problems under affine constraints on the parameter space. The theoretical study of this is motivated by the study of genetic determinants of diseases, such as diabetes, using external information from mediating protein expression levels. Specifically, we develop rigorous methods for estimating genetic effects on diabetes-related continuous outcomes when these associations are constrained based on external…

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Reinforcement Learning Based Computationally Efficient Conditional Choice Simulation Estimation of Dynamic Discrete Choice Models

基于强化学习的高效动态离散选择模型条件选择模拟估计

Dynamic discrete choice (DDC) models have found widespread application in marketing. However, estimating these becomes challenging in "big data" settings with high-dimensional state-action spaces. To address this challenge, this paper develops a Reinforcement Learning (RL)-based two-step ("computationally light") Conditional Choice Simulation (CCS) estimation approach that combines the scalability of machine learning with the transparency, explainability, and…

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