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Inferring Change Points in Regression via Sample Weighting

通过样本加权推断回归中的变点

We study the problem of identifying change points in high-dimensional generalized linear models, and propose an approach based on sample-weighted empirical risk minimization. Our method, Weighted ERM, encodes priors on the change points via weights assigned to each sample, to obtain weighted versions of standard estimators such as M-estimators and maximum-likelihood estimators. Under mild assumptions on the data, we obtain a precise asymptotic characterization of the…

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Principled Inference in Dense High-Dimensional Linear Models via Local Conditional Sparsity

基于局部条件稀疏性的稠密高维线性模型原则化推断

High-dimensional inference methods often rely on coefficient sparsity, an assumption that can be restrictive when signals are dense but individually weak. In such settings, valid inference may still be possible if the covariates exhibit sparse conditional dependence. Motivated by this observation, we propose Neighborhood-Localized Nested Regression (NLNR), a framework for coordinatewise inference in high-dimensional linear models with potentially dense coefficients. The…

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Average Marginal Effects in One-Step Partially Linear Instrumental Regressions

一步部分线性工具变量回归中的平均边际效应

We propose a novel procedure for estimating and conducting inference on average marginal effects in partially linear instrumental regressions using Reproducing Kernel Hilbert Space methods. Our procedure relies on a single regularization parameter. We obtain the consistency and asymptotic normality of our estimator. Since the variance of the limiting distribution has a complex analytical form, we propose a Bayesian bootstrap method to conduct inference and establish its…

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Prediction decomposition for causal analysis

用于因果分析的预测分解

There is rising interest in using Machine Learning (ML) model predictions as outcomes in causal analysis. However, these methods have faced challenges in finding the true treatment effects. It is also challenging to make choices about which prediction models to choose, since we are interested not only in the accuracy of the prediction but in its ability to produce the correct causal effect in the analysis. In this paper I propose a decomposition of the prediction into…

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Causal mediation in cluster-randomized trials with multiple mediators: spillover-aware decomposition, identification, and semiparametric efficient inference

多中介整群随机试验的因果中介分析:溢出分解、识别与有效推断

Causal mediation analysis in cluster-randomized trials (CRTs) is complicated by the presence of multiple mediators, intracluster correlation, and within-cluster interference. Existing mediation methods often fall short in accommodating these features simultaneously, and semiparametric efficient estimators that fully address them remain unavailable. We develop a unified framework that defines a class of mediation effect estimands, including exit indirect effects, exit…

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Transfer Learning for Moderate-Dimensional Ridge-Regularized Robust Linear Regression

中等维度岭正则化稳健线性回归的迁移学习

This paper studies transfer learning for ridge-regularized robust linear regression in the moderate-dimensional regime, where the number of predictors is of the same order as the sample size and the regression coefficients are not assumed to be sparse. We propose Trans-RR, which combines a robust ridge estimator from a source study with a robust ridge correction based on the target study. Under mild assumptions, we characterize the asymptotic estimation error of the proposed…

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Orthogonal machine learning for conditional odds and risk ratios

条件优势比与风险比的正交机器学习

Conditional effects are commonly used measures for understanding how treatment effects vary across different groups, and are often used to target treatments/interventions to groups who benefit most. In this work we review existing methods and propose novel ones, focusing on the odds ratio (OR) and the risk ratio (RR). While estimation of the conditional average treatment effect (ATE) has been widely studied, estimators for the OR and RR lag behind, and cutting edge…

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Estimating heterogeneous treatment effects with survival outcomes via a deep survival learner

利用深度生存学习器估计生存结局的异质性处理效应

Estimating heterogeneous treatment effects in survival settings is complicated by right censoring as well as the time-varying nature of the estimand. While the conditional average treatment effect (CATE) provides a natural target, most existing approaches focus on a single prespecified time point and do not account for the temporal trajectory, leading to instability in estimation. We propose a deep survival learner (DSL) for estimating heterogeneous treatment effects with…

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Gaussian Graphical Models for Functional Connectivity Analysis: A Statistical Review with Applications to Alzheimer's Disease

高斯图模型用于功能连接分析:面向阿尔茨海默病的统计综述

Functional connectivity analysis is an important tool for characterizing interactions among brain regions, particularly in studies of neurodegenerative disorders such as Alzheimer's disease (AD). Gaussian graphical models (GGMs) provide a promising statistical framework for estimating functional connectivity by capturing conditional dependence relationships among brain regions. Although a variety of regularized precision matrix estimators have been proposed to estimate…

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Differentially Private Estimation and Inference in High-Dimensional Regression with FDR Control

高维回归中的差分隐私估计与推断及FDR控制

This paper proposes new methodologies for conducting practical differentially private (DP) estimation and inference in high-dimensional linear regression. We first introduce a DP Bayesian Information Criterion (DP-BIC) for selecting the unknown sparsity parameter in differentially private sparse linear regression (DP-SLR), eliminating the need for prior knowledge of model sparsity, which is a requisite in the existing literature. Next, we develop the DP debiased algorithm…

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Training Neural Networks Embedded in Dynamic Discrete Choice Models

动态离散选择模型中嵌入神经网络的训练

We develop the first general-purpose estimator for infinite-horizon dynamic discrete choice models whose estimation problem, after pre-computation, is unencumbered by large systems of linear equations -- either imposed as constraints, or embedded in the objective function. Our unnested fixed point (UFXP) and optimal unnested fixed point (OUFXP) estimators exploit a dual representation of Bellman's equation to separate the utility parameters from the dynamic programming fixed…

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Quantum Reservoir Computing for Realized Volatility Forecasting

用于已实现波动率预测的量子储备池计算

Recent advances in quantum computing have demonstrated its potential to significantly enhance the analysis and forecasting of complex classical data. Among these, quantum reservoir computing has emerged as a particularly powerful approach, combining quantum computation with machine learning for modeling nonlinear temporal dependencies in high-dimensional time series. As with many data-driven disciplines, quantitative finance and econometrics can hugely benefit from emerging…

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Sample-split REGression SREG: A robust estimator for high-dimensional survey data

样本分割回归 SREG:高维调查数据的稳健估计量

Model-assisted regression estimation is fundamental in survey sampling for incorporating auxiliary information. However, when the auxiliary dimension grows with the sample size, the standard Generalized regression (GREG) estimator can exhibit non-negligible bias under informative sampling, even when the working model is correctly specified. This failure stems from the double use of sampled outcomes simultaneously for fitting the regression and for forming the residual…

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From Ground Truth to Measurement: A Statistical Framework for Human Labeling

从真实标签到测量:人类标注的统计框架

Supervised machine learning assumes that labeled data provide accurate measurements of the concepts models are meant to learn. Yet in practice, human labeling introduces systematic variation arising from ambiguous items, divergent interpretations, and simple mistakes. Machine learning research commonly treats all disagreement as noise, which obscures these distinctions and limits our understanding of what models actually learn. This paper reframes annotation as a measurement…

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A covariate-dependent Cholesky decomposition for high-dimensional covariance regression

协变量依赖的高维协方差回归的 Cholesky 分解

Estimation of covariance matrices is a fundamental problem in multivariate statistics. Recently, growing efforts have focused on incorporating covariate effects into these matrices, facilitating subject-specific estimation. Despite these advances, guaranteeing the positive definiteness of the resulting estimators remains a challenging problem. In this paper, we present a new varying-coefficient sequential regression framework that extends the modified Cholesky decomposition…

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Regularized estimation for highly multivariate spatial Gaussian random fields

高维多元空间高斯随机场的正则化估计

Estimating covariance parameters for multivariate spatial Gaussian random fields is computationally challenging, as the number of parameters grows rapidly with the number of variables, and likelihood evaluation requires operations of order $\mathcal{O}((np)^3)$. In many applications, however, not all cross-dependencies between variables are relevant, suggesting that sparse covariance structures may be both statistically advantageous and practically necessary. We propose a…

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Virtual Dummies: Enabling Scalable FDR-Controlled Variable Selection via Sequential Sampling of Null Features

虚拟哑变量:通过零特征序贯抽样实现可扩展的FDR受控变量选择

High-dimensional variable selection, particularly in genomics, requires error-controlling procedures that scale to millions of predictors. The Terminating-Random Experiments (T-Rex) selector achieves false discovery rate (FDR) control by aggregating results of early terminated random experiments, each combining original predictors with i.i.d. synthetic null variables (dummies). At biobank scales, however, explicit dummy augmentation requires terabytes of memory. We…

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Conformal Prediction with Time-Series Data via Sequential Conformalized Density Regions

通过序贯保形密度区域进行时间序列保形预测

We propose a new conformal prediction method for time-series data with a guaranteed asymptotic conditional coverage rate, Sequential Conformalized Density Regions (SCDR), which is flexible enough to produce both prediction intervals and disconnected prediction sets, signifying the emergence of bifurcations. Our approach uses existing estimated conditional highest density predictive regions to form initial predictive regions. We then use a quantile random forest conformal…

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A New Regression Lens on Multi-Class Classification

多类分类的回归新视角

Linear Discriminant Analysis (LDA) is a fundamental method for classification. Its simple linear structure facilitates interpretation, and it is naturally suited to multi-class settings. LDA is also closely connected to several classical multivariate techniques, including Fisher's discriminant analysis, canonical correlation analysis, and linear regression. In this paper, we strengthen the connection between LDA and multivariate response regression by establishing an…

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Non-asymptotic two-sample kernel testing with the spectrally truncated normalized MMD

基于谱截断归一化MMD的非渐近两样本核检验

Kernel methods provide a flexible and powerful framework for nonparametric statistical testing by embedding probability distributions into a reproducing kernel Hilbert space (RKHS). In this work, we study the kernel two-sample testing problem and focus on a normalized version of the Maximum Mean Discrepancy (MMD) as a test statistic, which scales the discrepancy by the within-group covariance operator to account for data variability. This normalization has been shown to…

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Time Series Gaussian Chain Graph Models

时间序列高斯链图模型

Time series graphical models have recently received considerable attention for characterizing (conditional) dependence structures in multivariate time series. In many applications, the multivariate series exhibit variable-partitioned blockwise dependence, with distinct patterns within and across blocks. In this paper, we introduce a new class of time series Gaussian chain graph models that represent contemporaneous and lagged causal relations via directed edges across…

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Transfer Learning for Robust Structured Regression with Bi-level Source Detection

面向稳健结构化回归的迁移学习与双层源域检测

High-dimensional data in modern applications, such as COVID-19 mortality, often span multiple domains. Leveraging auxiliary information from source domains to improve performance in a target domain motivates the use of transfer learning. However, a practical issue that has been overlooked is data contamination, which induces heterogeneity and can significantly degrade transfer learning performance. To address this challenge, we propose a novel approach that tackles transfer…

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Local Balance Calibration for Nonparametric Propensity Score Estimation

非参数倾向得分估计的局部平衡校准

The propensity score is widely used for causal inference in observational studies, but common parametric estimators can produce biased and inefficient effect estimates when model assumptions are violated. Nonparametric approaches reduce sensitivity to misspecification but often yield unstable weights and inadequate covariate balance. We propose Local Balance with Calibration, implemented by Neural Networks, a weighting method that combines flexible function approximation…

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Scalable Gaussian Process Regression Via Median Posterior Inference for Estimating Multi-Pollutant Mixture Health Effects

基于中位数后验推断的可扩展高斯过程回归:估计多污染物混合健康效应

Humans are exposed to complex mixtures of environmental pollutants rather than single chemicals, necessitating methods to quantify the health effects of such mixtures. Research on environmental mixtures provides insights into realistic exposure scenarios, informing regulatory policies that better protect public health. However, statistical challenges, including complex correlations among pollutants and nonlinear multivariate exposure-response relationships, complicate such…

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