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A Bayesian semi-parametric approach to causal mediation for longitudinal mediators and time-to-event outcomes with application to a cardiovascular disease cohort study

纵向中介与事件时间结局的贝叶斯半参数因果中介分析

Causal mediation analysis of observational data is an important tool for investigating the potential causal effects of medications on disease-related risk factors, and on time-to-death (or disease progression) through these risk factors. However, when analyzing data from a cohort study, such analyses are complicated by the longitudinal structure of the risk factors and the presence of time-varying confounders. Leveraging data from the Atherosclerosis Risk in Communities…

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Causal and Local Correlations Based Network for Multivariate Time Series Classification

基于因果与局部相关性的多元时间序列分类网络

Recently, time series classification has attracted the attention of a large number of researchers, and hundreds of methods have been proposed. However, these methods often ignore the spatial correlations among dimensions and the local correlations among features. To address this issue, the causal and local correlations based network (CaLoNet) is proposed in this study for multivariate time series classification. First, pairwise spatial correlations between dimensions are…

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Regularized Multi-LLMs Collaboration for Enhanced Score-based Causal Discovery

正则化多大语言模型协作辅助基于评分的因果发现

As the significance of understanding the cause-and-effect relationships among variables increases in the development of modern systems and algorithms, learning causality from observational data has become a preferred and efficient approach over conducting randomized control trials. However, purely observational data could be insufficient to reconstruct the true causal graph. Consequently, many researchers tried to utilise some form of prior knowledge to improve causal…

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Bayesian Variable Selection for High-Dimensional Mediation Analysis: Application to Metabolomics Data in Epidemiological Studies

高维中介分析的贝叶斯变量选择:流行病学代谢组数据应用

In epidemiological research, causal models incorporating potential mediators along a pathway are crucial for understanding how exposures influence health outcomes. This work is motivated by integrated epidemiological and blood biomarker studies, investigating the relationship between long-term adherence to a Mediterranean diet and cardiometabolic health, with plasma metabolomes as potential mediators. Analyzing causal mediation in such high-dimensional omics data presents…

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Scalable Spatiotemporal Prediction with Bayesian Neural Fields

利用贝叶斯神经场实现可扩展的时空预测

Spatiotemporal datasets, which consist of spatially-referenced time series, are ubiquitous in diverse applications, such as air pollution monitoring, disease tracking, and cloud-demand forecasting. As the scale of modern datasets increases, there is a growing need for statistical methods that are flexible enough to capture complex spatiotemporal dynamics and scalable enough to handle many observations. This article introduces the Bayesian Neural Field (BayesNF), a…

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spar: Sparse Projected Averaged Regression in R

spar:R 中的稀疏投影平均回归

Package spar for R builds ensembles of predictive generalized linear models with high-dimensional predictors. It employs an algorithm utilizing variable screening and random projection tools to efficiently handle the computational challenges associated with large sets of predictors. The package is designed with a strong focus on extensibility. Screening and random projection techniques are implemented as S3 classes with user-friendly constructor functions, enabling users to…

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Valid Bayesian Inference based on Variance Weighted Projection for High-Dimensional Logistic Regression with Binary Covariates

基于方差加权投影的高维二元协变量 Logistic 回归有效贝叶斯推断

We address the challenge of conducting inference for a categorical treatment effect related to a binary outcome variable while taking into account high-dimensional baseline covariates. The conventional technique used to establish orthogonality for the treatment effect from nuisance variables in continuous cases is inapplicable in the context of binary treatment. To overcome this obstacle, an orthogonal score tailored specifically to this scenario is formulated which is based…

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Variable selection via fused sparse-group lasso penalized multi-state models incorporating molecular data

融合稀疏组 lasso 惩罚的多状态模型变量选择及分子数据整合

In multi-state models based on high-dimensional data, effective modeling strategies are required to determine an optimal, ideally parsimonious model. In particular, linking covariate effects across transitions is needed to conduct joint variable selection. A useful technique to reduce model complexity is to address homogeneous covariate effects for distinct transitions. We integrate this approach to data-driven variable selection by extended regularization methods within…

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Confidence surfaces for the mean of locally stationary functional time series

局部平稳函数型时间序列均值的置信曲面

The problem of constructing a simultaneous confidence surface for the 2-dimensional mean function of a non-stationary functional time series is challenging as these bands can not be built on classical limit theory for the maximum absolute deviation between an estimate and the time-dependent regression function. In this paper, we propose a new bootstrap methodology to construct such a region. Our approach is based on a Gaussian approximation for the maximum norm of sparse…

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Debiased Regression for Root-N-Consistent Conditional Mean Estimation

用于条件均值根号样本量一致估计的去偏回归

This study introduces a debiasing method for regression estimators, including high-dimensional and nonparametric regression estimators. For example, nonparametric regression methods allow for the estimation of regression functions in a data-driven manner with minimal assumptions; however, these methods typically fail to achieve $\sqrt{n}$-consistency in their convergence rates, and many, including those in machine learning, lack guarantees that their estimators…

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Ridge, lasso, and elastic-net estimations of the modified Poisson and least-squares regressions for binary outcome data

二值结局的改进Poisson与最小二乘回归的岭、lasso与弹性网估计

Logistic regression is a standard method in multivariate analysis for binary outcome data in epidemiological and clinical studies; however, the resultant odds-ratio estimates fail to provide directly interpretable effect measures. The modified Poisson and least-squares regressions are alternative standard methods that can provide risk-ratio and risk difference estimates without computational problems. However, the bias and invalid inference problems of these regression…

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Modeling large dimensional matrix time series with partially known and latent factors

含部分已知因子与潜在因子的高维矩阵时间序列建模

This article considers to model large-dimensional matrix time series by introducing a regression term to the matrix factor model. This is an extension of classic matrix factor model to incorporate the information of known factors or useful covariates. We establish the convergence rates of coefficient matrix, loading matrices and the signal part. The theoretical results coincide with the rates in Wang et al. (2019). We conduct numerical studies to verify the performance of…

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AdaTrans: Feature-wise and Sample-wise Adaptive Transfer Learning for High-dimensional Regression

AdaTrans:高维回归中按特征与样本自适应的迁移学习

We consider the transfer learning problem in the high dimensional linear regression setting, where the feature dimension is larger than the sample size. To learn transferable information, which may vary across features or the source samples, we propose an adaptive transfer learning method that can detect and aggregate the feature-wise (F-AdaTrans) or sample-wise (S-AdaTrans) transferable structures. We achieve this by employing a fused-penalty, coupled with weights that can…

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Quantile deep learning models for multi-step ahead time series prediction

用于多步时间序列预测的分位数深度学习模型

Uncertainty quantification is crucial in time series prediction, and quantile regression offers a valuable mechanism for uncertainty quantification which is useful for extreme value forecasting. Although deep learning models have been prominent in multi-step ahead prediction, the development and evaluation of quantile deep learning models have been limited. We present a novel quantile regression deep learning framework for multi-step time series prediction. In this way, we…

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Robust Bayesian Model Averaging for Linear Regression Models With Heavy-Tailed Errors

重尾误差线性回归模型的稳健贝叶斯模型平均

Our goal is to develop a Bayesian model averaging technique in linear regression models that accommodates heavier tailed error densities than the normal distribution. Motivated by the use of the Huber loss function in the presence of outliers, the Bayesian Huberized lasso with hyperbolic errors has been proposed and recently implemented in the literature (Park and Casella (2008); Kawakami and Hashimoto (2023)). Since the Huberized lasso cannot enforce regression coefficients…

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Sample Complexity of Probability Divergences under Group Symmetry

群对称性下概率散度的样本复杂度

We rigorously quantify the improvement in the sample complexity of variational divergence estimations for group-invariant distributions. In the cases of the Wasserstein-1 metric and the Lipschitz-regularized $α$-divergences, the reduction of sample complexity is proportional to the group size if the group is finite. In addition to the published version at ICML 2023, our proof indeed has included the case when the group is infinite such as compact Lie groups, the convergence…

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Heavy-tailed Contamination is Easier than Adversarial Contamination

重尾污染比对抗性污染更容易

A large body of work in the statistics and computer science communities dating back to Huber (Huber, 1960) has led to statistically and computationally efficient outlier-robust estimators. Two particular outlier models have received significant attention: the adversarial and heavy-tailed models. While the former models outliers as the result of a malicious adversary manipulating the data, the latter relaxes distributional assumptions on the data allowing outliers to…

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High-Dimensional Extreme Quantile Regression

高维极端分位数回归

The estimation of conditional quantiles at extreme tails is of great interest in numerous applications. Various methods that integrate regression analysis with an extrapolation strategy derived from extreme value theory have been proposed to estimate extreme conditional quantiles in scenarios with a fixed number of covariates. However, these methods prove ineffective in high-dimensional settings, where the number of covariates increases with the sample size. In this article,…

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Prediction-Guided Active Experiments

预测引导的主动实验

In this work, we introduce a new framework for active experimentation, the Prediction-Guided Active Experiment (PGAE), which leverages predictions from an existing machine learning model to guide sampling and experimentation. Specifically, at each time step, an experimental unit is sampled according to a designated sampling distribution, and the actual outcome is observed based on an experimental probability. Otherwise, only a prediction for the outcome is available. We…

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Robust Inference for High-dimensional Linear Models with Heavy-tailed Errors via Partial Gini Covariance

基于偏基尼协方差的重尾误差高维线性模型稳健推断

This paper introduces the partial Gini covariance, a novel dependence measure that addresses the challenges of high-dimensional inference with heavy-tailed errors, often encountered in fields like finance, insurance, climate, and biology. Conventional high-dimensional regression inference methods suffer from inaccurate type I errors and reduced power in heavy-tailed contexts, limiting their effectiveness. Our proposed approach leverages the partial Gini covariance to…

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Jointly Modeling and Clustering Tensors in High Dimensions

高维张量的联合建模与聚类

We consider the problem of jointly modeling and clustering populations of tensors by introducing a high-dimensional tensor mixture model with heterogeneous covariances. To effectively tackle the high dimensionality of tensor objects, we employ plausible dimension reduction assumptions that exploit the intrinsic structures of tensors such as low-rankness in the mean and separability in the covariance. In estimation, we develop an efficient high-dimensional…

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Towards a framework on tabular synthetic data generation: a minimalist approach: theory, use cases, and limitations

面向表格合成数据生成的极简框架:理论、用例与局限

We propose and study a minimalist approach towards synthetic tabular data generation. The model consists of a minimalistic unsupervised SparsePCA encoder (with contingent clustering step or log transformation to handle nonlinearity) and XGboost decoder which is SOTA for structured data regression and classification tasks. We study and contrast the methodologies with (variational) autoencoders in several toy low dimensional scenarios to derive necessary intuitions. The…

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Empirical Bayes estimation: When does $g$-modeling beat $f$-modeling in theory (and in practice)?

经验贝叶斯估计:g 建模何时在理论上(及实践中)优于 f 建模?

Empirical Bayes (EB) is a popular framework for large-scale inference that aims to find data-driven estimators to compete with the Bayesian oracle that knows the true prior. Two principled approaches to EB estimation have emerged over the years: $f$-modeling, which constructs an approximate Bayes rule by estimating the marginal distribution of the data, and $g$-modeling, which estimates the prior from data and then applies the learned Bayes rule. For the Poisson model, the…

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Underlying Core Inflation with Multiple Regimes

多状态下的潜在核心通胀

This paper introduces a new approach for estimating core inflation indicators based on common factors across a broad range of price indices. Specifically, by utilizing procedures for detecting multiple regimes in high-dimensional factor models, we propose two types of core inflation indicators: one incorporating multiple structural breaks and another based on Markov switching. The structural breaks approach can eliminate revisions for past regimes, though it functions as an…

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