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Dependable Exploitation of High-Dimensional Unlabeled Data in an Assumption-Lean Framework

在弱假设框架下可靠利用高维无标签数据

Semi-supervised learning has attracted significant attention due to the proliferation of applications featuring limited labeled data but abundant unlabeled data. In this paper, we examine the statistical inference problem in an assumption-lean framework which involves a high-dimensional regression parameter, defined by minimizing the least squares, within the context of semi-supervised learning. We investigate when and how unlabeled data can enhance the estimation efficiency…

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Vertical Consensus Inference for High-Dimensional Random Partition

高维随机划分的纵向共识推断

We review recently proposed Bayesian approaches for clustering high-dimensional data. After identifying the main limitations of available approaches, we introduce an alternative framework based on vertical consensus inference (VCI) to mitigate the curse of dimensionality in high-dimensional Bayesian clustering. VCI builds on the idea of consensus Monte Carlo by dividing the data into multiple shards (smaller subsets of variables), performing posterior inference on each…

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Omitted-Variable Sensitivity Analysis for Generalizing Randomized Trials

随机试验结果推广的遗漏变量敏感性分析

Randomized controlled trials (RCTs) yield internally valid causal effect estimates, but generalizing these results to target populations with different characteristics requires an untestable selection ignorability assumption: conditional on observed covariates, trial participation must be independent of potential outcomes. This assumption fails when unobserved effect modifiers are distributed differently between trial and target populations. We develop a sensitivity analysis…

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Identifying Causal Effects Using Instrumental Variables from the Auxiliary Dataset

利用辅助数据集中的工具变量识别因果效应

Instrumental variable approaches have gained popularity for estimating causal effects in the presence of unmeasured confounders. However, the availability of instrumental variables in the primary dataset is often challenged due to stringent and untestable assumptions. This paper presents a novel method to identify and estimate causal effects by utilizing instrumental variables from the auxiliary dataset, incorporating a structural equation model, even in scenarios with…

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Identifiability of causal effects with non-Gaussianity and auxiliary covariates

利用非高斯性与辅助协变量识别因果效应

Assessing causal effects in the presence of unmeasured confounding is challenging. Although auxiliary variables, such as instrumental variables, are commonly used to identify causal effects, they are often unavailable in practice due to stringent and untestable conditions. To address this issue, previous researches have utilized linear structural equation models to show that the causal effect is identifiable when noise variables of the treatment and outcome are both…

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Combining BART and Principal Stratification to estimate the effect of intermediate on primary outcomes with application to estimating the effect of family planning on employment in sub-Saharan Africa

结合 BART 与主分层估计中间变量效应:撒哈拉以南非洲计划生育与就业

There is interest in learning about the causal effect of family planning (FP) on empowerment related outcomes. Experimental data related to this question are available from trials in which FP programs increase access to FP. While program assignment is unconfounded, FP uptake and subsequent empowerment may share common causes. We use principal stratification to estimate the causal effect of an intermediate FP outcome on a primary outcome of interest, among women affected by a…

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Combining BART and Principal Stratification to estimate the effect of intermediate variables on primary outcomes with application to estimating the effect of family planning on employment in Nigeria and Senegal

结合 BART 与主分层估计避孕使用对就业的影响:尼日利亚与塞内加尔

There is interest in learning about the causal effects of modern contraceptive use on empowerment outcomes. Data on this question often come from family planning (FP) programs that increase access to FP and facilitate contraceptive use among some women, rather than directly assigning use. Women whose contraceptive behavior changes because of these programs ("compliers") may differ from target populations in ways that alter the consequences of contraceptive use for…

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Diffolio: A Diffusion Model for Multivariate Probabilistic Financial Time-Series Forecasting and Portfolio Construction

Diffolio:多变量金融时序概率预测与组合构建的扩散模型

Probabilistic forecasting is crucial in multivariate financial time-series for constructing efficient portfolios that account for complex cross-sectional dependencies. In this paper, we propose Diffolio, a diffusion model designed for multivariate financial time-series forecasting and portfolio construction. Diffolio employs a denoising network with a hierarchical attention architecture, comprising both asset-level and market-level layers. Furthermore, to better reflect…

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Robust regularized covariance matrix estimation: well-posedness and convergent algorithm

稳健正则化协方差矩阵估计:适定性与收敛算法

In this paper, we study properties of penalized and structured M-estimators of multivariate scatter, based on geodesically convex but not necessarily smooth penalty functions. Existence and uniqueness conditions for these penalized and structured estimators are given. However, we show that the standard fixed-point algorithm which is usually applied to an M-estimation problem does not necessarily converge for penalized M-estimation problems. Hence, we develop a new but simple…

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Bayesian Variable Selection for Function-on-Scalar Regression Models: a comparative analysis

函数型因变量回归的贝叶斯变量选择:比较分析

In this work, we developed a new Bayesian method for variable selection in function-on-scalar regression (FOSR). Our method uses a hierarchical Bayesian structure and latent variables to enable an adaptive covariate selection process for FOSR. Extensive simulation studies show the proposed method's main properties, such as its accuracy in estimating the coefficients and high capacity to select variables correctly. Furthermore, we conducted a substantial comparative analysis…

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Mediation analysis with unmeasured confounding between parallel mediators and outcome

平行中介与结果之间存在未测混杂的中介分析

Mediation analysis extending beyond single mediators has gained significant attention in recent years. However, related methods often assume the absence of unmeasured mediator-outcome confounding. To address this, we develop a mediation analysis framework that accounts for such confounding within a linear structural equation model with parallel mediators. Specifically, we introduce a pseudo proxy variable to capture unmeasured confounding, allowing us to identify causal…

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Optimal Demixing of Nonparametric Densities

非参数密度的最优解混

Motivated by applications in statistics and machine learning, we consider a problem of unmixing convex combinations of nonparametric densities. Suppose we observe $n$ groups of samples, where the $i$th group consists of $N_i$ independent samples from a $d$-variate density $f_i(x)=\sum_{k=1}^K π_i(k)g_k(x)$. Here, each $g_k(x)$ is a nonparametric density, and each $π_i$ is a $K$-dimensional mixed membership vector. We aim to estimate $g_1(x), \ldots,g_K(x)$. This problem…

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A Nonparametric Framework for Universal Difference-in-Differences

通用双重差分的非参数框架

Difference-in-differences (DiD) is a popular approach to evaluate treatment effects in settings where both pre- and post-treatment measurements of the outcome are available. Despite its popularity, existing methods face important limitations. Specifically, they either: (i) only apply to continuous outcomes and the average treatment effect on the treated; (ii) are sensitive to the transformation of the outcome; (iii) rely on a no unmeasured confounding assumption given…

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Retrospective Counterfactual Prediction by Conditioning on the Factual Outcome: A Cross-World Approach

以事实结果为条件的回溯反事实预测:跨世界方法

Retrospective causal questions ask what would have happened to an observed individual had they received a different treatment. We study the problem of estimating $μ(x,y)=\mathbb{E}[Y(1)\mid X=x,Y(0)=y]$, the expected counterfactual outcome for an individual with covariates $x$ and observed outcome $y$, and constructing valid prediction intervals under the Neyman-Rubin superpopulation model. This quantity is generally not identified without additional assumptions. To link the…

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Data-driven Smooth Tests for Normality in ANOVA When the Number of Groups is Large

组数较大时方差分析正态性的数据驱动光滑检验

The normality assumption for random errors is fundamental in the analysis of variance (ANOVA) models. However, it is rarely subjected to formal testing in practice, and theoretically justified procedures are largely unavailable, especially when the number of groups diverges. In this paper, we develop Neyman's smooth tests for assessing normality in a broad class of ANOVA models, allowing the number of groups to diverge. The proposed test statistics are constructed via the…

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Cross-World Assumption and Refining Prediction Intervals for Individual Treatment Effects

跨世界假设与个体处理效应预测区间的细化

While average treatment effects (ATE) and conditional average treatment effects (CATE) provide valuable population- and subgroup-level summaries, they fail to capture uncertainty at the individual level. For high-stakes decision-making, individual treatment effect (ITE) estimates must be accompanied by valid prediction intervals that reflect heterogeneity and unit-specific uncertainty. However, the fundamental unidentifiability of ITEs limits the ability to derive precise…

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Maximin Learning of Individualized Treatment Effect on Multi-Domain Outcomes

多领域结局下个体化处理效应的最大最小学习

Precision mental health requires treatment decisions that account for heterogeneous symptoms reflecting multiple clinical domains. However, existing methods for estimating individualized treatment effects (ITE) rely on a single summary outcome or a specific set of observed symptoms or measures, which are sensitive to symptom selection and limit generalizability to unmeasured yet clinically relevant domains. We propose DRIFT, a new maximin framework for estimating robust ITEs…

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Non-robustness of diffusion estimates on networks with measurement error

测量误差下网络扩散估计的非稳健性

Network diffusion models are used to study disease transmission, information spread, technology adoption, and other socio-economic processes. We show that estimates of these diffusions are highly non-robust to mismeasurement. First, even when the network is measured perfectly, small and local mismeasurement in the initial seed generates a large shift in the locations of the expected diffusion. Second, if instead the initial seed is known, even a vanishingly small share of…

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Parameter Estimation in Stochastic Differential Equations via Wiener Chaos Expansion and Stochastic Gradient Descent

基于维纳混沌展开与随机梯度下降的随机微分方程参数估计

This study addresses the inverse problem of parameter estimation for Stochastic Differential Equations (SDEs) by minimizing a regularized discrepancy functional via Stochastic Gradient Descent (SGD). To achieve computational efficiency, we leverage the Wiener Chaos Expansion (WCE), a spectral decomposition technique that projects the stochastic solution onto an orthogonal basis of Hermite polynomials. This transformation effectively maps the stochastic dynamics into a…

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Bayesian analysis of the causal reference-based model for missing data in clinical trials, accommodating partially observed post-intercurrent event data

纳入部分伴发事件后观测的临床试验因果参考模型贝叶斯分析

When treatment policy estimands are of interest, clinical trials often attempt to collect patient data after intercurrent events (ICEs), although such data are often limited. Retrieved dropout imputation methods, which use pre-ICE and available post-ICE data to impute missing post-ICE outcomes, are commonly applied but often yield treatment effect estimates with large standard errors (SEs) and may encounter convergence issues when post-ICE data are sparse. Reference-based…

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A framework for joint assessment of a terminal event and a score existing only in the absence of the terminal event

终末事件与仅在事件未发生时存在的评分之联合评估框架

Analysis of data from randomized controlled trials in vulnerable populations requires special attention when assessing treatment effect by a score measuring, e.g., disease stage or activity together with onset of prevalent terminal events. In reality, it is impossible to disentangle a disease score from the terminal event, since the score is not clinically meaningful after this event. In this work, we propose to assess treatment interventions simultaneously on the terminal…

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A Calibration Framework for Inference with Partially Observed Data

部分观测数据推断的校准框架

Missing data is an universal problem in statistics. We develop a unified framework for estimating parameters defined by general estimating equations under a missing-at-random (MAR) mechanism, based on generalized entropy calibration weighting. We construct weights by minimizing a convex entropy subject to (i) balancing constraints on a data-adaptive calibration function, estimated using flexible machine-learning predictors with cross-fitting, and (ii) a debiasing constraint…

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A Bayesian Functional Concurrent Zero-Inflated Dirichlet-Multinomial Regression Model with Application to Infant Microbiome

贝叶斯函数型同期零膨胀狄利克雷-多项回归模型及其在婴儿微生物组中的应用

The infant microbiome undergoes rapid changes in composition over time and is associated with long-term risks of conditions such as immune strength, allergy, asthma, and other health outcomes. Modeling the associations between exposures or treatments and microbial composition over time is essential for understanding the factors that drive these changes. Estimating these temporal dynamics has several challenges including: repeated measures, overdispersion, compositionality,…

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Automatic Laplace Collapsed Sampling: Scalable Marginalisation of Latent Parameters via Automatic Differentiation

自动拉普拉斯折叠采样:以自动微分扩展潜在参数边际化

We present Automatic Laplace Collapsed Sampling (ALCS), a general framework for marginalising latent parameters in Bayesian models using automatic differentiation, which we combine with nested sampling to explore the hyperparameter space in a robust and efficient manner. At each nested sampling likelihood evaluation, ALCS collapses the high-dimensional latent variables $z$ to a scalar contribution via maximum a posteriori (MAP) optimisation and a Laplace approximation, both…

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