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Predicted Incrementality by Experimentation (PIE) for Ad Measurement

基于实验预测广告增量效果:PIE 广告衡量方法

Randomized controlled trials (RCTs) provide the most credible estimates of advertising incrementality but are difficult to scale. We propose Predicted Incrementality by Experimentation (PIE), which reframes ad measurement as a campaign-level prediction problem. PIE uses a sample of RCTs to learn a mapping from campaign features to causal effects, then applies it to campaigns not run as RCTs. Because the RCTs identify the causal effects, PIE can incorporate post-determined…

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Deconfounding Scores and Representation Learning for Causal Effect Estimation with Weak Overlap

弱重叠下因果效应估计的去混杂得分与表示学习

Overlap, also known as positivity, is a key condition for causal treatment effect estimation. Many popular estimators suffer from high variance and become brittle when features differ strongly across treatment groups. This is especially challenging in high dimensions: the curse of dimensionality can make overlap implausible. To address this, we propose a class of feature representations called deconfounding scores, which preserve both identification and the target of…

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Estimating causal effects of continuous-time dynamic treatments with unmeasured confounders

存在未测量混杂时连续时间动态处理的因果效应估计

Modern medical research demands specialized causal inference methods evaluating complex continuous-time dynamic treatment regimens using observational data. For instance, obtaining the causal effects of intravenous administration, a continuous process involving dynamic adjustments of the treatment dose, can guide clinicians on drug use. However, the existing causal inference frameworks in longitudinal studies typically assume that time advances in discrete time steps.…

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Identifying Drift, Diffusion, and Causal Structure from Temporal Snapshots

从时间快照识别漂移、扩散与因果结构

Stochastic differential equations (SDEs) are a fundamental tool for modelling dynamic processes, including gene regulatory networks (GRNs), contaminant transport, financial markets, and image generation. However, learning the underlying SDE from data is a challenging task, especially if individual trajectories are not observable. Motivated by burgeoning research in single-cell datasets, we present the first comprehensive approach for jointly identifying the drift and…

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Dynamic linear regression models for forecasting time series with semi long memory errors

具有半长记忆误差的动态线性回归预测模型

Dynamic linear regression models forecast the values of a time series based on a linear combination of a set of exogenous time series while incorporating a time series process for the error term. This error process is often assumed to follow a stationary autoregressive integrated moving average (ARIMA) model, or its seasonal variants, which are unable to capture a long-range dependence structure (long memory) of the error process. We propose a novel dynamic linear regression…

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Regularizing Extrapolation in Causal Inference

因果推断中的外推正则化

Many common estimators in machine learning and causal inference are linear smoothers, where the prediction is a weighted average of the training outcomes. Some estimators, such as ordinary least squares and kernel ridge regression, allow for arbitrarily negative weights, which improve feature imbalance but often at the cost of increased dependence on parametric modeling assumptions and higher variance. By contrast, estimators like importance weighting and random forests…

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Design Stability in Adaptive Experiments: Implications for Treatment Effect Estimation

自适应实验的设计稳定性及其对处理效应估计的影响

We study the problem of estimating the average treatment effect (ATE) under sequentially adaptive treatment assignment mechanisms. In contrast to classical completely randomized designs, we consider a setting in which the probability of assigning treatment to each experimental unit may depend on prior assignments and observed outcomes. Within the potential outcomes framework, we propose and analyze two natural estimators for the ATE: the inverse propensity weighted (IPW)…

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A generalized tetrad constraint for testing conditional independence given a latent variable

检验给定潜变量条件独立性的广义四元约束

The tetrad constraint is widely used to test whether four observed variables are conditionally independent given a latent variable, based on the fact that if four observed variables following a linear model are mutually independent after conditioning on an unobserved variable, then products of covariances of any two different pairs of these four variables are equal. It is an important tool for discovering a latent common cause or distinguishing between alternative linear…

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Constructive Instrumental Variable Identification and Inference with Many Weak Interaction Moments

利用大量弱交互矩的构造性工具变量识别与推断

Instrumental variable methods are widely used for causal inference, but identification becomes especially challenging when instruments are weak and potentially invalid. These challenges are particularly pronounced in Mendelian randomization, where genetic variants serve as instruments and violations of exclusion restriction or independence assumptions are common. We propose MAGIC, a constructive and assumption-lean framework that achieves identification even when all…

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Linear models for causal inference under network interference

网络干扰下因果推断的线性模型

In causal inference, interference occurs when the treatment of one unit may affect the outcomes of other units. The goal of this work is to serve as a guide to the use of linear outcome modeling for estimating causal effects in settings where interference may pose a challenge to identification and estimation, such as spatial and network data. We demonstrate that, under a linear model, causal effects of binary and continuous treatments can be identified in terms of regression…

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When Bayes goes bad: Weakly-regularized covariate adjustment leads to a biased estimate of prevalence

当贝叶斯方法失效:弱正则化协变量调整导致患病率估计偏倚

When estimating population prevalence from a non-random sample, it is important to adjust for differences between sample and population. However, adjustment for multiple factors requires analysis that can be difficult to understand and validate. In this manuscript, we explore an unexpected downward trend of estimates when covariates are added sequentially to a Bayesian hierarchical model for the estimation of the prevalence of SARS-CoV-2 specific antibodies in an Australian…

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Optimal Data Integration and Adaptive Sampling for Efficient Treatment Effect Estimation

高效处理效应估计的最优数据整合与自适应抽样

This study addresses the challenge of estimating average treatment effects (ATEs) for advertising campaigns in online marketplaces where complete randomized experimentation is infeasible. We propose two key innovations: (1) a shrinkage estimator that optimally combines observational and experimental data without assuming smooth treatment effects across campaigns, and (2) a Bayesian adaptive experimental design framework that efficiently selects campaigns for randomized…

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A Unified Framework for Nonlinear Mediation Analysis of Random Objects

随机对象非线性中介分析的统一框架

Mediation analysis for complex, non-Euclidean data, such as probability distributions, compositions, images, and networks, presents significant methodological challenges due to the inherent nonlinearity and geometric constraints of such spaces. Existing approaches are often restricted to Euclidean settings or specific data types. We propose Random Object Mediation Analysis (ROMA), a unified framework that simultaneously accommodates object-valued exposures, mediators, and…

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Likelihood-Free Inference via Structured Score Matching

基于结构化得分匹配的无似然推断

In many statistical problems, the data distribution is specified through a generative process for which the likelihood function is analytically intractable, yet inference on the associated model parameters remains of primary interest. We develop a likelihood-free inference framework that combines score matching with gradient-based optimization and bootstrap procedures to facilitate parameter estimation together with uncertainty quantification. The proposed methodology…

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Unbiased Estimation of Central Moments in Unbalanced Two- and Three-Level Models

非平衡两层与三层模型中中心矩的无偏估计

This paper derives closed-form unbiased estimators of central moments in multilevel random-effects models with unbalanced group sizes. In a two-level model, we provide unbiased estimators for the second, third, and fourth central moments under both group-level and observation-level averaging. In a three-level model, we provide unbiased estimators for the second and third central moments.

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Linear Regression from 1-bit Quantized Data

基于1比特量化数据的线性回归

Motivated by the prevalence of environments in which data is abundant while resources for storage and/or transmission might be scarce, we study linear regression when predictors, their squares, and responses are subject to single-bit dithered quantization. An estimator relying on plug-in estimation of the quadratic and linear terms in the quadratic program formulation of the least squares problem is proposed. We provide a non-asymptotic bound on the $\ell_2$-estimation error…

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Inference on Optimal Policy Values and Other Irregular Functionals via Softmax Smoothing

通过 Softmax 平滑推断最优政策价值及其他非正则泛函

Constructing confidence intervals for the value of an (unknown) optimal treatment policy is a fundamental problem in causal inference. Insight into the optimal policy value can guide the development of reward-maximizing, individualized treatment regimes. However, because the functional that defines the optimal value is non-differentiable, standard semi-parametric approaches for performing inference fail to be directly applicable. Many existing works circumvent…

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Sensitivity Analysis for Instrumental Variables Under Joint Relaxations of Monotonicity and Independence

同时放宽单调性与独立性的工具变量敏感性分析

In this paper I develop a breakdown frontier approach to assess the sensitivity of Local Average Treatment Effects (LATE) estimates to violations of monotonicity and independence of the instrument. I parametrize violations of independence using the concept of $c$-dependence from Masten & Poirier (2018) and allow for the share of defiers to be greater than zero but smaller than the share of compliers. I derive identified sets for the LATE and the Average Treatment Effect…

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Identifying the desert decision rule to assess and achieve fairness

识别应得决策规则以评估与实现公平

We study fairness in decision-making when the data may encode systematic bias. Existing approaches typically impose fairness constraints while predicting the observed decision, which may itself be unfair. We propose a novel framework for characterising and addressing fairness issues by introducing the notion of desert decision, a latent variable representing the decision an individual rightfully deserves based on their actions, efforts, or abilities. This formulation shifts…

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The Conjugate Domain Dichotomy: Exact Risk of M-Estimators under Infinite-Variance Noise in High Dimensions

共轭域二分法:高维无限方差噪声下M估计的精确风险

This paper studies high-dimensional M-estimation in the proportional asymptotic regime (p/n -> gamma > 0) when the noise distribution has infinite variance. For noise with regularly-varying tails of index alpha in (1,2), we establish that the asymptotic behavior of a regularized M-estimator is governed by a single geometric property of the loss function: the boundedness of the domain of its Fenchel conjugate. When this conjugate domain is bounded -- as is the case for the…

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Fake Date Tests: Can We Trust In-sample Accuracy of LLMs in Macroeconomic Forecasting?

伪日期检验:大语言模型宏观预测的样本内准确性可信吗?

Large language models (LLMs) are a type of machine learning tool that economists have started to apply in their empirical research. One such application is macroeconomic forecasting with backtesting of LLMs, even though they are trained on the same data that is used to estimate their forecasting performance. Can these in-sample accuracy results be extrapolated to the model's out-of-sample performance? To answer this question, we developed a family of prompt sensitivity tests…

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Parametric generalized spectrum for heavy-tailed time series

厚尾时间序列的参数化广义谱

Recently, several spectra have emerged, designed to encapsulate the distributional characteristics of non-Gaussian stationary processes. This article introduces parametric families of generalized spectra based on the characteristic function, alongside inference procedures enabling $\sqrt{n}$-consistent estimation of the unknown parameters in a broad class of parametric models. These spectra capture non-linear dependencies without requiring that the underlying stochastic…

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Identifying Genetic Variants for Obesity: A Knowledge Integration Quantile Regression (KIQR) Approach for Ultra-High-Dimensional Data

面向肥胖遗传变异的超高维数据知识整合分位数回归方法

Obesity is widely recognized as a serious and pervasive health concern. We study obesity through body mass index (BMI), which is known to be highly heritable, and identify important genetic risk factors for BMI from hundreds of thousands of single nucleotide polymorphisms (SNPs) in the Framingham Study data. Several challenges arise when using traditional genome-wide association studies (GWAS): (1) They suffer from a low power due to a combination of a limited number of…

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Gimbal Regression: Orientation-Adaptive Local Linear Regression under Spatial Heterogeneity

Gimbal 回归:空间异质性下方向自适应的局部线性回归

Local regression is widely used to explore spatial heterogeneity, but anisotropic or effectively low-dimensional neighborhoods can produce ill-conditioned local solves, causing coefficient variation driven by numerical artifacts rather than substantive structure. Such instability is often hidden when estimation relies on implicit tuning or optimization without exposing local diagnostics. This paper proposes Gimbal Regression (GR), a deterministic, geometry-aware local…

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