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Debiased inference for stochastic treatment interventions with survival outcomes

生存结局下随机治疗干预的去偏推断

Estimating the causal effect of a time-dependent treatment on time to death is challenging. In this paper, we formulate the problem using the illness-death model and focus on a stochastic intervention that modifies the hazard governing the transition from no treatment to treatment initiation. Such an intervention can only be implemented at the level of the observed data, whereas the causally valid intervention is defined at the level of the true data-generating process. We…

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Multi-task Linear Regression without Eigenvalue Lower Bounds: Adaptivity, Robustness, and Safety

无特征值下界约束的多任务线性回归:自适应性、稳健性与安全性

We study the multi-task linear regression problem in the presence of contaminated tasks. We address the setting where the unknown parameters of a majority of tasks are close in the $\ell_2$-norm, while a fraction of tasks are arbitrary outliers. Existing theoretical frameworks for this problem rely heavily on the assumption that the empirical second moment of each task has a minimum eigenvalue bounded away from zero (order $Ω(1)$). Crucially, this assumption fails in many…

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Additive Matrix Integer-Valued Autoregressive Model

加性矩阵整数值自回归模型

Contemporary data-driven and technology-integrated era, various matrix-valued integer-valued time series, such as cross-regional crime statistics, multi-category sales records, and network traffic matrices, exhibit high dimensionality, complex structures, and strong row-column intertwined dependencies. Although the existing matrix integer-valued autoregressive (MINAR) model provides a framework that directly handles matrix data and captures bidirectional row-column…

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A Lecture Note on Offline RL and IRL, Part II: Foundations of Inverse Reinforcement Learning and Dynamic Discrete Choice Models

离线强化学习与逆强化学习讲义(二):逆强化学习与动态离散选择基础

In the forward reinforcement-learning problem, the reward is fixed and known; the learner is asked to find a good policy or value function. Here we turn the question around. Given offline data generated by an expert, can we recover the reward the expert was optimizing? This is the inverse reinforcement learning problem, and remarkably, two communities, structural econometricians studying dynamic discrete choice (DDC) and machine learners studying entropy-regularized IRL,…

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Unified theory of testing relevant hypotheses in functional time series

函数型时间序列实质性假设检验的统一理论

In this paper, we develop a {\em unified} framework for testing relevant hypotheses in functional time series. The proposed approach accommodates one-sample, two-sample, and change point problems for contaminated observations under arbitrary sampling schemes. Combining B-spline estimation with self-normalization, we construct nuisance-parameter-free tests that bypass auxiliary estimation of long-run covariance functions and measurement-error variance functions. We establish…

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Moment-Based Inference for Regression with Latent Dirichlet Covariates

潜在狄利克雷协变量回归的矩推断

Topic models are often used as dimension-reduction tools before regression, with estimated document-level topic shares treated as observed covariates. This plug-in workflow creates two inferential difficulties: valid inference requires a regular first-stage-to-second-stage expansion that propagates topic-estimation uncertainty, and, at fixed document length, a document's topic mixture cannot be consistently recovered from its own words even when the population topic matrix…

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Learning General Causal Structures with Hidden Dynamic Process for Climate Analysis

气候分析中含隐藏动态过程的一般因果结构学习

Understanding climate dynamics requires going beyond correlations in observational data to uncover the underlying causal process. Latent drivers such as atmospheric processes play a central role in temporal dynamics, while direct causal influences also exist among geographically proximate observed variables. Traditional Causal Representation Learning (CRL) typically focuses on latent factors but overlooks such observable-to-observable causal relations, which limits its…

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Dynamic Co-Expression Network Estimation via Multivariate Mixed-Effects Models

基于多元混合效应模型的动态共表达网络估计

High-throughput sequencing technologies have enabled the collection of large-scale longitudinal -omics data, providing new opportunities for studying co-expression networks among molecular nodes such as genes and proteins. However, the high dimensionality and temporal dependence inherent in such data require specialized statistical methods. We propose a novel approach to infer dynamic co-expression networks among features over time (DCENt), where each node (feature) is…

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Restricted mean time lost for survival and competing risks data using mets in R

使用 R 包 mets 分析生存与竞争风险数据的限制平均损失时间

This paper introduces software implemented in the mets R-package for calculating non-parametric and regression estimates of Restricted Mean Survival Time (RMST) and Restricted Mean Time Lost (RMTL), including RMTL due to specific causes. A unique feature is the ability to compute the non-parametric estimates of RMST and RMTL, as well as their standard errors, for all time horizons simultaneously. Regression modeling in mets is based on Inverse Probability of Censoring…

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Shrinkage-Constrained Functional Calibration for Complex Computer Models

面向复杂计算机模型的收缩约束函数标定

We propose a new Bayesian model calibration formalism as an alternative to the Kennedy O'Hagan (KOH) framework which we term integrated bias with full uncertainty (IBFU). In KOH, calibration parameters are modeled as fixed, but unknown distributions with relatively weak prior constraints, and their posteriors are inferred jointly with an additive discrepancy Gaussian Process (GP). This formulation often provides limited regularization and leads to confounding pathologies…

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Improved Guarantees for Heterogeneous Treatment-Effect Estimation via Matrix Completion

通过矩阵补全改进异质性处理效应估计的理论保证

A central goal of modern causal inference is estimating heterogeneous treatment effects to answer questions like "how does an intervention affect each unit," rather than only on average. We study this problem with panel-data where we observe $n$ units across $m$ times under unknown, non-uniform treatment assignments. The data in this setting is naturally represented as a matrix of all unit--time treatment effects. Estimating heterogeneous treatment effects can then be…

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Semiparametric Inference for Causal Effects on Functional Outcomes

函数型结局因果效应的半参数推断

Difference-in-differences (DiD) is a cornerstone of causal inference, yet extending it to functional outcomes is not a routine scalar generalization; rather, it entails three fundamental challenges in identification, inference, and observation. This paper develops a comprehensive semiparametric inference framework for functional DiD with discretely observed data. First, we define the functional average treatment effect under parallel trends and derive its efficient influence…

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Robust Inference for Convex Pairwise Difference Estimators

凸成对差分估计量的稳健推断

This paper develops distribution theory and bootstrap-based inference methods for a broad class of convex pairwise difference estimators. These estimators minimize a kernel-weighted convex-in-parameter function over observation pairs with similar covariates, where the similarity is governed by a localization (bandwidth) parameter. While classical results establish asymptotic normality under restrictive bandwidth conditions, we show that valid Gaussian and bootstrap-based…

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A Doubly Robust GMM Estimator for Sequential Non-monotone Missingness

序贯非单调缺失下的双重稳健 GMM 估计量

We study moment-based estimation with two sequentially collected variables subject to non-monotone missingness. The commonly used Missing at Random (MAR) assumption requiring all missingness mechanisms to depend on the same fully observed covariates often fails in such cases. We introduce a sequential MAR assumption that allows asymmetric missingness mechanisms across stages. Based on this assumption, we construct an Augmented Inverse-Probability-Weighted GMM (AIPW-GMM)…

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rd2d: Causal Inference in Boundary Discontinuity Designs

rd2d:边界断点设计中的因果推断软件

Boundary Discontinuity (BD) designs are used in empirical research to learn about causal treatment effects along a continuous assignment boundary defined by a bivariate score. These designs are also known as multi-score regression discontinuity (RD) designs, and include geographic RD designs as a prominent example. This article introduces \pkg{rd2d}, a statistical software package for \proglang{R}, \proglang{Python}, and \proglang{Stata} that implements local polynomial…

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Exact Likelihood Inference and Robust Filtering for Gauss-Cauchy Convolution Models

高斯—柯西卷积模型的精确似然推断与稳健滤波

The convolution of a Gaussian and a Cauchy distribution, known as the Voigt distribution, is widely used in spectroscopy and provides a natural framework for modeling heavy-tailed measurement noise. We derive analytical expressions for its density, score, Hessian, Fisher information, and conditional moments using the scaled complementary error function, enabling stable maximum likelihood estimation without numerical convolution, finite-difference derivatives, or pseudo-Voigt…

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Bridging Maximum Likelihood and Optimal Transport for Efficient Inference and Model Selection in Stochastic Block Models

连接最大似然与最优传输:随机块模型的高效推断与模型选择

We study inference in stochastic block models (SBMs) through the lens of optimal transport (OT). We first establish that maximum likelihood variational inference (MLVI) can be interpreted as a semi-relaxed Gromov-Wasserstein (srGW) projection with entropic regularization. While this formulation yields accurate clustering, the entropic regularization prevents transport plans to be sparse, hindering intrinsic model selection. Consequently, we investigate unregularized srGW…

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Change-point estimation for Weibull time series with copula-based Markov models

基于 Copula 马尔可夫模型的 Weibull 时间序列变点估计

We study offline change-point estimation for time series data exhibiting nonlinear serial dependence. To address this problem, we propose a copula-based Markov chain model with Weibull marginal distributions, which is suitable for modeling nonnegative data such as event times and volatility measures. Nonlinear dependence is incorporated through the Clayton and Joe copulas, allowing the model to capture asymmetric lower-tail and upper-tail dependence structures, respectively.…

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Estimating Continuous Treatment Effects with Two-Stage Kernel Ridge Regression

利用两阶段核岭回归估计连续处理效应

We study the problem of estimating the effect function for a continuous treatment, which maps each treatment value to a population-averaged outcome. A central challenge in this setting is confounding: treatment assignment often depends on covariates, creating selection bias that makes direct regression of the response on treatment unreliable. To address this issue, we propose a two-stage kernel ridge regression method. In the first stage, we learn a model for the response as…

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Generalized Spectral Testing with Sample Splitting

采用样本分割的广义谱检验

Residual-based goodness-of-fit tests for parametric time-series models are often complicated by parameter-estimation effects, which can alter the limiting behavior of diagnostic statistics. We propose a sample-splitting generalized spectral test (in the spirit of Escanciano(2006)) for assessing conditional mean specification in linear and nonlinear time-series models. The procedure estimates the model parameter on a fitting subsample and constructs a generalized spectral…

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Identification and Inference for Structural Accelerated Failure Time Models via Instrument Interactions

利用工具变量交互识别与推断结构加速失效时间模型

We study causal inference for time-to-event outcomes under right censoring in the presence of unmeasured confounding. Focusing on structural accelerated failure time models, we develop an identification and inference framework that exploits interactions among instrumental variables. The proposed approach does not rely on classical instrumental variable validity and yields valid causal inference under both valid and invalid instruments, provided that the interaction-based…

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Outcome-Calibrated Regression and Predicted Outcome-Based Inference

结果校准回归与基于预测结果的推断

Regression is a fundamental tool in scientific research. Ordinary least squares (OLS), one of the most widely used regression methods, enjoys several desirable properties, including the best linear unbiased estimator (BLUE) property. It is well known that, under the assumptions of the standard model, the OLS is conditionally unbiased given the covariates, i.e., $\mathbb{E}(\widehat Y-Y\mid X=x)=0$. However, an often-overlooked property of OLS is that the prediction error is…

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Graph Neural Networks for Generalized Mundlak Estimator under Network Confounding

网络混杂下基于图神经网络的广义 Mundlak 估计量

This paper proposes a generalized Mundlak estimator based on graph neural networks (GME-GNN). The estimator is designed to mitigate bias arising from group-level heterogeneity and to accommodate within-group dependence among individuals. Traditional fixed-effects models handle group heterogeneity via group-specific intercepts, but require overly strict linear additivity and intra-group independence assumptions, and are confined to within-group comparisons. Rather than…

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Estimating within-cluster and between-cluster spillover effects in randomized saturation designs

随机饱和度设计中簇内与簇间溢出效应的估计

Randomized saturation designs are two-stage experiments: they first randomly assign treatment probabilities over the clusters and then randomly assign the treatment to the units within the clusters. The existing literature on randomized saturation designs focuses on estimating within-cluster spillover effects by assuming away between-cluster spillover effects. However, the units may interact across clusters in many practical randomized saturation designs. A leading example…

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