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A mixture of distributed lag non-linear models to account for spatially heterogeneous exposure-lag-response associations

刻画空间异质性暴露—滞后—响应关系的分布滞后非线性混合模型

Environmental exposures, such as air pollution and extreme temperatures, have complex effects on human health. These effects are often characterized by non-linear exposure-lag-response relationships and delayed impacts over time. Accurately capturing these dynamics is crucial for informing public health interventions. The Distributed Lag Non-Linear Model (DLNM) is a flexible statistical framework for estimating such effects in epidemiological research. However, standard DLNM…

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Conformal and kNN Predictive Uncertainty Quantification Algorithms in Metric Spaces

度量空间中的共形与近邻预测不确定性量化

This paper introduces a framework for uncertainty quantification in regression models defined on metric spaces. Using a proposed notion of homoscedasticity, we define a conformal prediction algorithm that provides finite-sample marginal coverage guarantees and fast convergence rates to the oracle prediction region. For heteroscedastic settings, we introduce a kNN procedure that yields locally adaptive prediction radii in general metric spaces. Although this procedure does…

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Large-Scale Estimation under Unknown Heteroskedasticity

未知异方差下的大规模估计

This paper studies nonparametric empirical Bayes methods in a heterogeneous parameters framework that features unknown means and variances. We provide extended Tweedie's formulae that express the (infeasible) optimal estimators of heterogeneous parameters, such as unit-specific means or quantiles, in terms of the density of certain sufficient statistics. These are used to propose feasible versions with nearly parametric regret bounds of the order of $(\log n)^κ/ n$. The…

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Generalized nonparametric regression in reproducing kernel Hilbert spaces: Consistency and rates of convergence

再生核希尔伯特空间中的广义非参数回归:相合性与收敛速率

We develop a comprehensive theory for regularized M-estimation in reproducing kernel Hilbert spaces. Under mild conditions on the loss we establish existence and measurability of the estimator, covering a wide range of convex and non-convex losses, including bounded robust losses. We further prove sharp rates of convergence with an explicit bias-variance decomposition governed by a novel complexity measure. We show that the variance is independent of misspecification, while…

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Change Point Detection in Precision Matrices with D-trace Loss

基于D-trace损失的精度矩阵变点检测

We consider the problem of estimating a time-varying sparse precision matrix, which is assumed to evolve in a piecewise constant manner. Building upon the Group Fused LASSO and LASSO penalty functions, we estimate both the precision matrix and the change points. We propose an alternative estimator to the commonly employed Gaussian likelihood loss, namely the D-trace loss. We provide the conditions for the consistency of the estimated change points and of the sparse…

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Robust Expectation-Maximization for Covariance Estimation in SIRV Models with Missing Data: Application to InSAR Time Series

缺失数据 SIRV 模型中的稳健 EM 协方差估计及 InSAR 时间序列应用

This paper presents a robust Expectation-Maximization framework for covariance estimation in Scale-Invariant Random Vector (SIRV) models with missing data under ignorable missingness mechanisms. By adopting an inverse-gamma prior on the scale variables, the resulting observation model leads to a complex multivariate Student-t distribution and allows closed-form E-step and M-step updates. The proposed algorithm incorporates numerical robustness techniques such as computation…

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From Risk Sets to Martingales: A Counting-Process Framework for Event-History Learning

从风险集到鞅:事件史学习的计数过程框架

Counting-process notation separates predictable risk-set information from observed event jumps through decompositions of the form dN(t)=Y(t)alpha(t)dt+dM(t). This article develops a unified event-history learning framework for censored, truncated, recurrent, multistate, and covariate-dependent data. Rather than cataloguing survival methods, the treatment translates each partially observed learning target into five recurring objects: risk process, jump process, compensator,…

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Sensitivity Analysis for the Average Treatment Effect under Discrete Unobserved Confounders

离散未观测混杂下平均处理效应的敏感性分析

We model unobserved confounding through an unknown finite number of latent types. This assumption induces finite-mixture representations of the treated and control outcome distributions. Using the identified mixture components, we characterize the sharp identified set for the number of latent types and derive the sharp identified set for the average treatment effect (ATE) corresponding to each admissible value, thereby providing a natural framework for sensitivity analysis.…

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Leniency Designs: An Operator's Manual

宽严度设计:操作指南

We develop a step-by-step guide to leniency (a.k.a. judge or examiner instrument) designs, drawing on recent econometric literatures. The unbiased jackknife instrumental variables estimator (UJIVE) is purpose-built for leveraging exogenous leniency variation, avoiding subtle biases even in the presence of many decision-makers or controls. We show how UJIVE can also be used to assess key assumptions underlying leniency designs, including quasi-random assignment and average…

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Semi-knockoffs: a model-agnostic conditional independence testing method with finite-sample guarantees

半敲诈:一种具有有限样本保证的模型无关条件独立性检验方法

Conditional independence testing (CIT) is essential for reliable scientific discovery. It prevents spurious findings and enables controlled feature selection. Recent CIT methods have used machine learning (ML) models as surrogates of the underlying distribution. However, model-agnostic approaches require a train-test split, which reduces statistical power. We introduce Semi-knockoffs, a CIT method that can accommodate any pre-trained model, avoids this split, and provides…

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Inference methods for unit-specific coefficients in panel data models with latent group structure

潜在分组面板模型中个体特定系数的推断方法

This paper introduces statistical inference procedures for unit-specific coefficients in panel data models, where the coefficients exhibit a latent group structure. The proposed methods achieve efficiency gains by clustering units into a small number of groups, while explicitly accounting for the statistical uncertainty of group assignments. The core idea is to integrate standard inference procedures, such as the $t$-test and Wald tests, with confidence sets for group…

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Invariant quantile regression for heterogeneous environments

异质环境下的不变量分位数回归

In this paper, we propose an invariant quantile regression (IQR) framework specifically designed for multi-environment datasets, which captures the invariance across different environments. This framework is closely related to transfer learning, causal inference, and fair machine learning, and is motivated by scenarios in which the conditional probability of the response given covariates varies, while certain key variables remain invariant. This perspective differs notably…

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On the use of auxiliary variables in multiple imputation when estimating the average causal effect with missing data

缺失数据下估计平均因果效应时,多重插补中辅助变量的使用

Estimating the average causal effect (ACE) using observational data is a key focus in causal inference for which missing data present an important challenge. Multiple imputation (MI) is a widely used method for handling missing data and can yield unbiased estimates when the imputation is compatible with the substantive analysis. One of the advantages of MI is its scope to include so-called "auxiliary variables", defined as variables associated with incomplete variables that…

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EnsembleIV: Creating Instrumental Variables from Ensemble Learners for Robust Statistical Inference with ML-Generated Variables

EnsembleIV:从集成学习器构造工具变量以处理机器学习生成变量

Despite increasing popularity in empirical studies, the integration of machine learning generated variables into regression models for statistical inference suffers from the measurement error problem, which can bias estimation and threaten the validity of inferences. In this paper, we develop a novel approach to alleviate associated estimation biases. Our proposed approach, EnsembleIV, creates valid and strong instrumental variables from weak learners in an ensemble model,…

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On the Curse of Dimensionality in Private Sparse Covariance Estimation and PCA

差分隐私稀疏协方差估计与PCA的维数灾难

We study high-dimensional differentially private (DP) covariance estimation in the operator norm, and principal component analysis (PCA), under $k$-row-column sparsity ($k$-RCS) of the covariance matrix. In the non-private setting, it is known that $\mathsf{poly}(k, \log d)$ samples suffice to solve both of these problems. However, the only comparable result known under DP (Wang et al. 2021) requires $Ω(d)$ samples under standard parameterizations of the problem. We…

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Fast Nonparametric Conditional Independence Testing via Two-Stage Regression

通过两阶段回归快速进行非参数条件独立检验

Constraint-based causal discovery relies on repeated conditional independence tests, but fast nonparametric tests often sacrifice calibration, especially when variables depend on the conditioning set through nonlinear relationships. We introduce BLITZ (Broad-to-Local Independence Testing via residualiZation), a nonparametric conditional independence test designed to run well under a second while maintaining the accuracy needed for the thousands of queries performed by…

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Nonparametric Deconvolution and Denoising using Simulation Based Inference

基于模拟推断的非参数去卷积与去噪

Latent signals are often obscured by measurement noise, yet encode the underlying laws and dynamics of complex systems; learning both the signals and their distributions remains a central challenge in scientific inference. The noise is often non-negligible, and the likelihoods for expressive generative models are often intractable. We utilize a convolutional maximum mean discrepancy (convMMD) loss and propose a likelihood-free framework for nonparametric density…

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Deconfounding via Profiled Transfer Learning

通过剖面化迁移学习消除混杂

Unmeasured confounders are a major source of bias in regression-based effect estimation and causal inference. In this paper, we propose a new profiled transfer learning framework, ProTrans, to address confounding effects in the target dataset, when additional source datasets with similar confounding structures are available. We introduce the concept of profiled residuals to characterize the shared confounding patterns between source and target datasets. By incorporating…

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A New Targeted-Federated Learning Framework for Estimating Heterogeneity of Treatment Effects: A Robust Framework with Applications in Aging Cohorts

估计处理效应异质性的目标联邦学习框架:稳健方法与老龄队列应用

Analyzing data from multiple sources offers valuable opportunities to improve the estimation efficiency of causal estimands. However, this analysis also poses many challenges due to population heterogeneity and data privacy constraints. While several advanced methods for causal inference in federated settings have been developed in recent years, many focus on difference-based averaged causal effects and are not designed to study effect modification. In this study, we…

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A Test for Treatment Heterogeneity under a Distributional Difference-in-Difference Framework

分布双重差分框架下的处理异质性检验

We develop a novel distributional Difference-in-Differences (DiD) framework to capture treatment heterogeneity across outcome distributions. By leveraging optimal transport, we use the control group to estimate the untreated distributional drift from the pre- to post-treatment period and apply it to the treated group's pre-treatment baseline, constructing a counterfactual distribution under the assumption of no treatment effect. We frame the null hypothesis as a…

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Privacy-preserving Meta-analysis through Low-Rank Basis Hunting

通过低秩基函数搜寻实现保护隐私的元分析

A central challenge of meta-analysis is that the populations underlying existing studies often differ from the target population in unknown ways. We study the problem of predicting function-valued quantities, such as regression and conditional average treatment effect functions, for a new target population using only study-level covariates and study-specific function estimates. We propose MetaHunt, a new meta-analysis methodology based on a shared low-rank structure, in…

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Estimating Representative Causal Effects with Double Machine Learning

用双重机器学习估计具有总体代表性的因果效应

Double Machine Learning is widely used to estimate treatment effects from non-experimental data. The "residuals-on-residuals" regression (RORR) is especially popular for its simplicity and computational tractability. However, with heterogeneous treatment effects, the proper interpretation of RORR may not be well understood. We show that, for non-binary treatments with continuous dose-response functions, RORR estimates a conditional variance-weighted average of derivatives…

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Design-Based Inference under Random Potential Outcomes

随机潜在结果下的基于设计的推断

We study whether mechanism-level causal estimands, defined as expectations over latent stochastic environments, can be consistently recovered from a single realised randomised experiment. Identification alone does not guarantee recoverability. The target estimand averages over latent environments, whereas a single experiment provides only one realisation of such an environment. We show that suitably sparse local dependence induces an ergodic-type property under which…

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Bregman projection for calibration estimation in Survey Sampling

调查抽样校准估计中的 Bregman 投影

Calibration weighting is a fundamental tool in survey sampling for incorporating auxiliary population information into design-based estimators. Classical formulations measure distance between calibrated and design weights on the multiplicative ratio scale. We develop a unified framework based on Bregman divergence defined directly on the weight vector. The framework reveals a primal--dual symmetry in which both the weight-space and multiplier-space optimization problems are…

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