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隐半马尔可夫模型的序贯贝叶斯学习AI 解读

In this paper, we explore the class of the Hidden Semi-Markov Model (HSMM), a flexible extension of the popular Hidden Markov Model (HMM) that allows the underlying stochastic process to be a semi-Markov chain. HSMMs are typically used less frequently than their basic HMM counterpart due to the increased computational challenges when evaluating the likelihood function. Moreover, while both models are sequential in nature, parameter estimation is mainly conducted via batch…

个体化处理效应估计中的对抗去混杂AI 解读

Observational studies have recently received significant attention from the machine learning community due to the increasingly available non-experimental observational data and the limitations of the experimental studies, such as considerable cost, impracticality, small and less representative sample sizes, etc. In observational studies, de-confounding is a fundamental problem of individualised treatment effects (ITE) estimation. This paper proposes disentangled…

因子结构结局研究中对未观测混杂的敏感性AI 解读

In this work, we propose an approach for assessing sensitivity to unobserved confounding in studies with multiple outcomes. We demonstrate how prior knowledge unique to the multi-outcome setting can be leveraged to strengthen causal conclusions beyond what can be achieved from analyzing individual outcomes in isolation. We argue that it is often reasonable to make a shared confounding assumption, under which residual dependence amongst outcomes can be used to simplify and…

时间序列的灵活条件密度估计AI 解读

This paper introduces FlexCodeTS, a new conditional density estimator for time series. FlexCodeTS is a flexible nonparametric conditional density estimator, which can be based on an arbitrary regression method. It is shown that FlexCodeTS inherits the rate of convergence of the chosen regression method. Hence, FlexCodeTS can adapt its convergence by employing the regression method that best fits the structure of data. From an empirical perspective, FlexCodeTS is compared to…

利用二元工具变量在未观测混杂下估计个体处理效应AI 解读

Estimating conditional average treatment effects (CATEs) from observational data is relevant in many fields such as personalized medicine. However, in practice, the treatment assignment is usually confounded by unobserved variables and thus introduces bias. A remedy to remove the bias is the use of instrumental variables (IVs). Such settings are widespread in medicine (e.g., trials where the treatment assignment is used as binary IV). In this paper, we propose a novel,…

混合随机化与断点设计的核回归分析AI 解读

Tie-breaker experimental designs are hybrids of Randomized Controlled Trials (RCTs) and Regression Discontinuity Designs (RDDs) in which subjects with moderate scores are placed in an RCT while subjects with extreme scores are deterministically assigned to the treatment or control group. In settings where it is unfair or uneconomical to deny the treatment to the more deserving recipients, the tie-breaker design (TBD) trades off the practical advantages of the RDD with the…

数据受限条件下的因果推断AI 解读

This dissertation focuses on modern causal inference under uncertainty and data restrictions, with applications to neoadjuvant clinical trials, distributed data networks, and robust individualized decision making. In the first project, we propose a method under the principal stratification framework to identify and estimate the average treatment effects on a binary outcome, conditional on the counterfactual status of a post-treatment intermediate response. Under mild…

基于因子调整向量自回归的高维时间序列分段AI 解读

Vector autoregressive (VAR) models are popularly adopted for modelling high-dimensional time series, and their piecewise extensions allow for structural changes in the data. In VAR modelling, the number of parameters grow quadratically with the dimensionality which necessitates the sparsity assumption in high dimensions. However, it is debatable whether such an assumption is adequate for handling datasets exhibiting strong serial and cross-sectional correlations. We propose…

协变量调整的对数秩检验：效率增益与广泛适用性AI 解读

Nonparametric covariate adjustment is considered for log-rank type tests of treatment effect with right-censored time-to-event data from clinical trials applying covariate-adaptive randomization. Our proposed covariate-adjusted log-rank test has a simple explicit formula and a guaranteed efficiency gain over the unadjusted test. We also show that our proposed test achieves universal applicability in the sense that the same formula of test can be universally applied to simple…

平均处理效应的回归调整插补估计量AI 解读

Imputing missing potential outcomes using an estimated regression function is a natural idea for estimating causal effects. In the literature, estimators that combine imputation and regression adjustments are believed to be comparable to augmented inverse probability weighting. Accordingly, people for a long time conjectured that such estimators, while avoiding directly constructing the weights, are also doubly robust (Imbens, 2004; Stuart, 2010). Generalizing an earlier…

稳定概率加权：有限重叠下多值处理异质性因果效应的估计与推断AI 解读

In this paper, I try to tame "Basu's elephants" (data with extreme selection on observables). I propose new practical large-sample and finite-sample methods for estimating and inferring heterogeneous causal effects (under unconfoundedness) in the empirically relevant context of limited overlap. I develop a general principle called "Stable Probability Weighting" (SPW) that can be used as an alternative to the widely used Inverse Probability Weighting (IPW) technique, which…

通过 MCMC 实现经典估计的方法AI 解读

This paper studies computationally and theoretically attractive estimators called the Laplace type estimators (LTE), which include means and quantiles of Quasi-posterior distributions defined as transformations of general (non-likelihood-based) statistical criterion functions, such as those in GMM, nonlinear IV, empirical likelihood, and minimum distance methods. The approach generates an alternative to classical extremum estimation and also falls outside the parametric…

用于反事实估计的最优传输方法AI 解读

Many problems ask a question that can be formulated as a causal question: "what would have happened if...?" For example, "would the person have had surgery if he or she had been Black?" To address this kind of questions, calculating an average treatment effect (ATE) is often uninformative, because one would like to know how much impact a variable (such as skin color) has on a specific individual, characterized by certain covariates. Trying to calculate a conditional ATE…

事件时间结局的主分层分析AI 解读

Post-randomization events, also known as intercurrent events, such as treatment noncompliance and censoring due to a terminal event, are common in clinical trials. Principal stratification is a framework for causal inference in the presence of intercurrent events. Despite the extensive existing literature, there lacks generally applicable and accessible methods for principal stratification analysis with time-to-event outcomes. In this paper, we specify two causal estimands…

倾向得分模型的稳健估计及因果目标量应用：综述与新方案AI 解读

In observational study, the propensity score has the central role to estimate causal effects. Since the propensity score is usually unknown, estimating by appropriate procedures is an indispensable step. A point to note that a causal effect estimator might have some bias if a propensity score model was misspecified; valid model construction is important. To overcome the problem, a variety of interesting methods has been proposed. In this paper, we review four methods: using…

典型多变量缺失机制下因果效应的可恢复性与估计AI 解读

In the context of missing data, the identifiability or "recoverability" of the average causal effect (ACE) depends on causal and missingness assumptions. The latter can be depicted by adding variable-specific missingness indicators to causal diagrams, creating "missingness-directed acyclic graphs" (m-DAGs). Previous research described ten canonical m-DAGs, representing typical multivariable missingness mechanisms in epidemiological studies, and determined the recoverability…

无对照组两时点数据的重抽样因果推断及健康风险应用AI 解读

Two-point time-series data, characterized by baseline and follow-up observations, are frequently encountered in health research. We study a novel two-point time series structure without a control group, which is driven by an observational routine clinical dataset collected to monitor key risk markers of type-$2$ diabetes (T2D) and cardiovascular disease (CVD). We propose a resampling approach called 'I-Rand' for independently sampling one of the two time points for each…

SUTSE 模型的快速同期预测及理论性质AI 解读

We consider the problem of forecasting multivariate time series by a Seemingly Unrelated Time Series Equations (SUTSE) model. The SUTSE model usually assumes that error variables are correlated. A crucial issue is that the model estimation requires heavy computational loads because of a large matrix computation, especially for high-dimensional data. To alleviate the computational issue, we propose a two-stage procedure for forecasting. First, we perform the Kalman filter as…

利用半正定规划构造通用预测带AI 解读

We propose a computationally efficient method to construct nonparametric, heteroscedastic prediction bands for uncertainty quantification, with or without any user-specified predictive model. Our approach provides an alternative to the now-standard conformal prediction for uncertainty quantification, with novel theoretical insights and computational advantages. The data-adaptive prediction band is universally applicable with minimal distributional assumptions, has strong…

含外生变量的对数空间异方差模型及统计推断AI 解读

The spatial dependence in mean has been well studied by plenty of models in a large strand of literature, however, the investigation of spatial dependence in variance is lagging significantly behind. The existing models for the spatial dependence in variance are scarce, with neither probabilistic structure nor statistical inference procedure being explored. To circumvent this deficiency, this paper proposes a new generalized logarithmic spatial heteroscedasticity model with…

加性单指标协整时间序列模型的稳健 M 估计AI 解读

Robust M-estimation uses loss functions, such as least absolute deviation (LAD), quantile loss and Huber's loss, to construct its objective function, in order to for example eschew the impact of outliers, whereas the difficulty in analysing the resultant estimators rests on the nonsmoothness of these losses. Generalized functions have advantages over ordinary functions in several aspects, especially generalized functions possess derivatives of any order. Generalized…

因子数量未知时的稀疏贝叶斯因子分析AI 解读

There has been increased research interest in the subfield of sparse Bayesian factor analysis with shrinkage priors, which achieve additional sparsity beyond the natural parsimonity of factor models. In this spirit, we estimate the number of common factors in the highly implemented sparse latent factor model with spike-and-slab priors on the factor loadings matrix. Our framework leads to a natural, efficient and simultaneous coupling of model estimation and selection on one…

类别型背景变量下的深度反事实估计AI 解读

Referred to as the third rung of the causal inference ladder, counterfactual queries typically ask the "What if ?" question retrospectively. The standard approach to estimate counterfactuals resides in using a structural equation model that accurately reflects the underlying data generating process. However, such models are seldom available in practice and one usually wishes to infer them from observational data alone. Unfortunately, the correct structural equation model is…

高维控制变量下条件平均处理效应的双重稳健推断AI 解读

Plausible identification of conditional average treatment effects (CATEs) may rely on controlling for a large number of variables to account for confounding factors. In these high-dimensional settings, estimation of the CATE requires estimating first-stage models whose consistency relies on correctly specifying their parametric forms. While doubly-robust estimators of the CATE exist, inference procedures based on the second stage CATE estimator are not doubly-robust. Using…