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The Blessings of Multiple Treatments and Outcomes in Treatment Effect Estimation

多处理与多结果对处理效应估计的助益

Assessing causal effects in the presence of unobserved confounding is a challenging problem. Existing studies leveraged proxy variables or multiple treatments to adjust for the confounding bias. In particular, the latter approach attributes the impact on a single outcome to multiple treatments, allowing estimating latent variables for confounding control. Nevertheless, these methods primarily focus on a single outcome, whereas in many real-world scenarios, there is greater…

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Uniform Inference for Kernel Density Estimators with Dyadic Data

成对关系数据核密度估计的一致推断

Dyadic data is often encountered when quantities of interest are associated with the edges of a network. As such it plays an important role in statistics, econometrics and many other data science disciplines. We consider the problem of uniformly estimating a dyadic Lebesgue density function, focusing on nonparametric kernel-based estimators taking the form of dyadic empirical processes. Our main contributions include the minimax-optimal uniform convergence rate of the dyadic…

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Clip-OGD: An Experimental Design for Adaptive Neyman Allocation in Sequential Experiments

Clip-OGD:序贯实验中自适应 Neyman 分配的实验设计

From clinical development of cancer therapies to investigations into partisan bias, adaptive sequential designs have become increasingly popular method for causal inference, as they offer the possibility of improved precision over their non-adaptive counterparts. However, even in simple settings (e.g. two treatments) the extent to which adaptive designs can improve precision is not sufficiently well understood. In this work, we study the problem of Adaptive Neyman Allocation…

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Smoothed instrumental variables quantile regression

平滑工具变量分位数回归

In this article, I introduce the sivqr command, which estimates the coefficients of the instrumental variables (IV) quantile regression model introduced by Chernozhukov and Hansen (2005). The sivqr command offers several advantages over the existing ivqreg and ivqreg2 commands for estimating this IV quantile regression model, which complements the alternative "triangular model" behind cqiv and the "local quantile treatment effect" model of ivqte. Computationally, sivqr…

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Estimating Average Treatment Effects in Regression Discontinuity Designs with Covariates under Minimal Assumptions

最小假设下含协变量的断点回归平均处理效应估计

We study regression discontinuity designs with the use of additional covariates for estimation of the average treatment effect. We provide a detailed proof of asymptotic normality of the covariate-adjusted estimator under minimal assumptions, which may serve as an accessible text to the mathematics behind regression discontinuity with covariates. In addition, this proof carries at least three benefits. First of all, it allows to draw straightforward consequences concerning…

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Double and Single Descent in Causal Inference with an Application to High-Dimensional Synthetic Control

因果推断中的双重下降与单调下降:高维合成控制应用

Motivated by a recent literature on the double-descent phenomenon in machine learning, we consider highly over-parameterized models in causal inference, including synthetic control with many control units. In such models, there may be so many free parameters that the model fits the training data perfectly. We first investigate high-dimensional linear regression for imputing wage data and estimating average treatment effects, where we find that models with many more…

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Design-Based RCT Estimators and Central Limit Theorems for Baseline Subgroup and Related Analyses

基线子组及相关分析的设计型随机试验估计量与中心极限定理

There is a growing literature on design-based methods to estimate average treatment effects (ATEs) for randomized controlled trials (RCTs) for full sample analyses. This article extends these methods to estimate ATEs for discrete subgroups defined by pre-treatment variables, with an application to an RCT testing subgroup effects for a school voucher experiment in New York City. We consider ratio estimators for subgroup effects using regression methods, allowing for model…

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Testing Quantile Forecast Optimality

分位数预测最优性的检验

Quantile forecasts made across multiple horizons have become an important output of many financial institutions, central banks and international organisations. This paper proposes misspecification tests for such quantile forecasts that assess optimality over a set of multiple forecast horizons and/or quantiles. The tests build on multiple Mincer-Zarnowitz quantile regressions cast in a moment equality framework. Our main test is for the null hypothesis of autocalibration, a…

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Network Synthetic Interventions: A Causal Framework for Panel Data Under Network Interference

网络合成干预:网络干扰下的面板数据因果框架

We propose a generalization of the synthetic controls and synthetic interventions methodology to incorporate network interference. We consider the estimation of unit-specific potential outcomes from panel data in the presence of spillover across units and unobserved confounding. Key to our approach is a novel latent factor model that takes into account network interference and generalizes the factor models typically used in panel data settings. We propose an estimator,…

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Factor Augmented Sparse Throughput Deep ReLU Neural Networks for High Dimensional Regression

用于高维回归的因子增强稀疏直通深度 ReLU 神经网络

This paper introduces a Factor Augmented Sparse Throughput (FAST) model that utilizes both latent factors and sparse idiosyncratic components for nonparametric regression. The FAST model bridges factor models on one end and sparse nonparametric models on the other end. It encompasses structured nonparametric models such as factor augmented additive models and sparse low-dimensional nonparametric interaction models and covers the cases where the covariates do not admit factor…

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G-formula for causal inference via multiple imputation

通过多重插补实现因果推断中的 G 公式

G-formula is a popular approach for estimating treatment or exposure effects from longitudinal data that are subject to time-varying confounding. G-formula estimation is typically performed by Monte-Carlo simulation, with non-parametric bootstrapping used for inference. We show that G-formula can be implemented by exploiting existing methods for multiple imputation (MI) for synthetic data. This involves using an existing modified version of Rubin's variance estimator. In…

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Statistical inference of high-dimensional vector autoregressive time series with non-i.i.d. innovations

非独立同分布创新下高维向量自回归时间序列的统计推断

Independent or i.i.d. innovations is an essential assumption in the literature for analyzing a vector time series. However, this assumption is either too restrictive for a real-life time series to satisfy or is hard to verify through a hypothesis test. This paper performs statistical inference on a sparse high-dimensional vector autoregressive time series, allowing its white noise innovations to be dependent, even non-stationary. To achieve this goal, it adopts a…

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Systematic simulation of age-period-cohort analysis: Demonstrating bias of Bayesian regularization

年龄—时期—队列分析的系统模拟:贝叶斯正则化偏差

Age-period-cohort (APC) analysis is one of the fundamental time-series analyses used in the social sciences. This paper evaluates APC analysis via systematic simulation in term of how well the artificial parameters are recovered. We consider three models of Bayesian regularization using normal prior distributions: the random effects model with reference to multilevel analysis, the ridge regression model equivalent to the intrinsic estimator, and the random walk model…

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Cross-validatory model selection for Bayesian autoregressions with exogenous regressors

含外生回归变量的贝叶斯自回归模型:交叉验证与模型选择

Bayesian cross-validation (CV) is a popular method for predictive model assessment that is simple to implement and broadly applicable. A wide range of CV schemes is available for time series applications, including generic leave-one-out (LOO) and K-fold methods, as well as specialized approaches intended to deal with serial dependence such as leave-future-out (LFO), h-block, and hv-block. Existing large-sample results show that both specialized and generic methods are…

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Positivity-free Policy Learning with Observational Data

无需正值性假设的观察数据政策学习

Policy learning utilizing observational data is pivotal across various domains, with the objective of learning the optimal treatment assignment policy while adhering to specific constraints such as fairness, budget, and simplicity. This study introduces a novel positivity-free (stochastic) policy learning framework designed to address the challenges posed by the impracticality of the positivity assumption in real-world scenarios. This framework leverages incremental…

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Ultra-high dimensional confounder selection algorithms comparison with application to radiomics data

超高维混杂变量选择算法比较及影像组学应用

Radiomics is an emerging area of medical imaging data analysis particularly for cancer. It involves the conversion of digital medical images into mineable ultra-high dimensional data. Machine learning algorithms are widely used in radiomics data analysis to develop powerful decision support model to improve precision in diagnosis, assessment of prognosis and prediction of therapy response. However, machine learning algorithms for causal inference have not been previously…

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Treatment Choice, Mean Square Regret and Partial Identification

处理选择、均方遗憾与部分识别

We consider a decision maker who faces a binary treatment choice when their welfare is only partially identified from data. We contribute to the literature by anchoring our finite-sample analysis on mean square regret, a decision criterion advocated by Kitagawa, Lee, and Qiu (2022). We find that optimal rules are always fractional, irrespective of the width of the identified set and precision of its estimate. The optimal treatment fraction is a simple logistic transformation…

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Learning domain-specific causal discovery from time series

从时间序列学习领域特定的因果发现方法

Causal discovery (CD) from time-varying data is important in neuroscience, medicine, and machine learning. Techniques for CD encompass randomized experiments, which are generally unbiased but expensive, and algorithms such as Granger causality, conditional-independence-based, structural-equation-based, and score-based methods that are only accurate under strong assumptions made by human designers. However, as demonstrated in other areas of machine learning, human expertise…

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Spectral norm bounds for high-dimensional realized covariance matrices and application to weak factor models

高维已实现协方差矩阵的谱范数界及弱因子模型应用

Motivated by statistical analysis of latent factor models for high-frequency financial data, we develop sharp upper bounds for the spectral norm of the realized covariance matrix of a high-dimensional Itô semimartingale with possibly infinite activity jumps. For this purpose, we develop Burkholder-Gundy type inequalities for matrix martingales with the help of the theory of non-commutative $L^p$ spaces. The obtained bounds are applied to estimating the number of (relevant)…

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Robust Minimum Distance Inference in Structural Models

结构模型中的稳健最小距离推断

This paper proposes minimum distance inference for a structural parameter of interest, which is robust to the lack of identification of other structural nuisance parameters. Some choices of the weighting matrix lead to asymptotic chi-squared distributions with degrees of freedom that can be consistently estimated from the data, even under partial identification. In any case, knowledge of the level of under-identification is not required. We study the power of our robust…

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A neutral comparison of statistical methods for time-to-event analyses under non-proportional hazards

非比例风险下生存分析统计方法的中立比较

While well-established methods for time-to-event data are available when the proportional hazards assumption holds, there is no consensus on the best inferential approach under non-proportional hazards (NPH). However, a wide range of parametric and non-parametric methods for testing and estimation in this scenario have been proposed. To provide recommendations on the statistical analysis of clinical trials where non proportional hazards are expected, we conducted a…

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Projecting infinite time series graphs to finite marginal graphs using number theory

用数论将无限时间序列图投影为有限边际图

In recent years, a growing number of method and application works have adapted and applied the causal-graphical-model framework to time series data. Many of these works employ time-resolved causal graphs that extend infinitely into the past and future and whose edges are repetitive in time, thereby reflecting the assumption of stationary causal relationships. However, most results and algorithms from the causal-graphical-model framework are not designed for infinite graphs.…

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On the mixed-model analysis of covariance in cluster-randomized trials

整群随机试验中的混合模型协方差分析

In the analyses of cluster-randomized trials, mixed-model analysis of covariance (ANCOVA) is a standard approach for covariate adjustment and handling within-cluster correlations. However, when the normality, linearity, or the random-intercept assumption is violated, the validity and efficiency of the mixed-model ANCOVA estimators for estimating the average treatment effect remain unclear. Under the potential outcomes framework, we prove that the mixed-model ANCOVA…

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Identification and Estimation in a Class of Potential Outcomes Models

一类潜在结果模型的识别与估计

This paper develops a class of potential outcomes models characterized by three main features: (i) Unobserved heterogeneity can be represented by a vector of potential outcomes and a type describing the manner in which an instrument determines the choice of treatment; (ii) The availability of an instrumental variable that is conditionally independent of unobserved heterogeneity; and (iii) The imposition of convex restrictions on the distribution of unobserved heterogeneity.…

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