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An iterative algorithm for high-dimensional linear models with both sparse and non-sparse structures

含稀疏与非稀疏结构的高维线性模型迭代算法

Numerous practical medical problems often involve data that possess a combination of both sparse and non-sparse structures. Traditional penalized regularizations techniques, primarily designed for promoting sparsity, are inadequate to capture the optimal solutions in such scenarios. To address these challenges, this paper introduces a novel algorithm named Non-sparse Iteration (NSI). The NSI algorithm allows for the existence of both sparse and non-sparse structures and…

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Counterfactually Comparing Abstaining Classifiers

以反事实方式比较可拒绝预测的分类器

Abstaining classifiers have the option to abstain from making predictions on inputs that they are unsure about. These classifiers are becoming increasingly popular in high-stakes decision-making problems, as they can withhold uncertain predictions to improve their reliability and safety. When evaluating black-box abstaining classifier(s), however, we lack a principled approach that accounts for what the classifier would have predicted on its abstentions. These missing…

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Implementing measurement error models with mechanistic mathematical models in a likelihood-based framework for estimation, identifiability analysis, and prediction in the life sciences

在基于似然的框架中实现测量误差模型与机制数学模型:生命科学中的估计、可识别性分析与预测

Throughout the life sciences we routinely seek to interpret measurements and observations using parameterised mechanistic mathematical models. A fundamental and often overlooked choice in this approach involves relating the solution of a mathematical model with noisy and incomplete measurement data. This is often achieved by assuming that the data are noisy measurements of the solution of a deterministic mathematical model, and that measurement errors are additive and…

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Bootstrap inference in the presence of bias

存在偏误时的 Bootstrap 推断

We consider bootstrap inference for estimators which are (asymptotically) biased. We show that, even when the bias term cannot be consistently estimated, valid inference can be obtained by proper implementations of the bootstrap. Specifically, we show that the prepivoting approach of Beran (1987, 1988), originally proposed to deliver higher-order refinements, restores bootstrap validity by transforming the original bootstrap p-value into an asymptotically uniform random…

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Flexibly Estimating and Interpreting Heterogeneous Treatment Effects of Laparoscopic Surgery for Cholecystitis Patients

灵活估计与解释胆囊炎患者腹腔镜手术的异质性治疗效应

Laparoscopic surgery has been shown through a number of randomized trials to be an effective form of treatment for cholecystitis. Given this evidence, one natural question for clinical practice is: does the effectiveness of laparoscopic surgery vary among patients? It might be the case that, while the overall effect is positive, some patients treated with laparoscopic surgery may respond positively to the intervention while others do not or may be harmed. In our study, we…

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How Much Should We Trust Instrumental Variable Estimates in Political Science? Practical Advice Based on Over 60 Replicated Studies

政治学中的工具变量估计有多可信?基于六十余项复现的实践建议

Instrumental variable (IV) strategies are widely used in political science to establish causal relationships. However, the identifying assumptions required by an IV design are demanding, and it remains challenging for researchers to assess their validity. In this paper, we replicate 67 papers published in three top journals in political science during 2010-2022 and identify several troubling patterns. First, researchers often overestimate the strength of their IVs due to…

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On Gaussian Process Priors in Conditional Moment Restriction Models

条件矩限制模型中的高斯过程先验

This paper studies quasi Bayesian estimation and uncertainty quantification for an unknown function that is identified by a nonparametric conditional moment restriction. We derive contraction rates for a class of Gaussian process priors. Furthermore, we provide conditions under which a Bernstein von Mises theorem holds for the quasi-posterior distribution. As a consequence, we show that optimally weighted quasi-Bayes credible sets have exact asymptotic frequentist coverage.

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Asymmetric predictability in causal discovery: an information theoretic approach

因果发现中的预测不对称性:信息论方法

Causal investigations in observational studies pose a great challenge in research where randomized trials or intervention-based studies are not feasible. We develop an information geometric causal discovery and inference framework of "predictive asymmetry". For $(X, Y)$, predictive asymmetry enables assessment of whether $X$ is more likely to cause $Y$ or vice-versa. The asymmetry between cause and effect becomes particularly simple if $X$ and $Y$ are deterministically…

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Asymptotic Properties of Endogeneity Corrections Using Nonlinear Transformations

利用非线性变换修正内生性的渐近性质

This paper considers a linear regression model with an endogenous regressor which arises from a nonlinear transformation of a latent variable. It is shown that the corresponding coefficient can be consistently estimated without external instruments by adding a rank-based transformation of the regressor to the model and performing standard OLS estimation. In contrast to other approaches, our nonparametric control function approach does not rely on a conformably specified…

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Debiased Fixed Effects Estimation of Binary Logit Models with Three-Dimensional Panel Data

三维面板二元 Logit 模型的去偏固定效应估计

Naive maximum likelihood estimation of binary logit models with fixed effects leads to unreliable inference due to the incidental parameter problem. We study the case of three-dimensional panel data, where the model includes three sets of additive and overlapping unobserved effects. This encompasses models for network panel data, where senders and receivers maintain bilateral relationships over time, and fixed effects account for unobserved heterogeneity at the sender-time,…

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Exposure Effects on Count Outcomes with Observational Data, with Application to Incarcerated Women

观察数据中暴露对计数结果的效应:以被监禁女性为例

Causal inference methods can be applied to estimate the effect of a point exposure or treatment on an outcome of interest using data from observational studies. For example, in the Women's Interagency HIV Study, it is of interest to understand the effects of incarceration on the number of sexual partners and the number of cigarettes smoked after incarceration. In settings like this where the outcome is a count, the estimand is often the causal mean ratio, i.e., the ratio of…

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A Ridge-Regularised Jackknifed Anderson-Rubin Test

岭正则化的刀切 Anderson–Rubin 检验

We consider hypothesis testing in instrumental variable regression models with few included exogenous covariates but many instruments -- possibly more than the number of observations. We show that a ridge-regularised version of the jackknifed Anderson Rubin (1949, henceforth AR) test controls asymptotic size in the presence of heteroskedasticity, and when the instruments may be arbitrarily weak. Asymptotic size control is established under weaker assumptions than those…

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Graphical tools for selecting conditional instrumental sets

选择条件工具变量集合的图形工具

We consider the efficient estimation of total causal effects in the presence of unmeasured confounding using conditional instrumental sets. Specifically, we consider the two-stage least squares estimator in the setting of a linear structural equation model with correlated errors that is compatible with a known acyclic directed mixed graph. To set the stage for our results, we characterize the class of linearly valid conditional instrumental sets that yield consistent…

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Estimation and inference for transfer learning with high-dimensional quantile regression

高维分位数回归中的迁移学习估计与推断

Transfer learning has become an essential technique to exploit information from the source domain to boost performance of the target task. Despite the prevalence in high-dimensional data, heterogeneity and heavy tails are insufficiently accounted for by current transfer learning approaches and thus may undermine the resulting performance. We propose a transfer learning procedure in the framework of high-dimensional quantile regression models to accommodate heterogeneity and…

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Optimal Treatment Allocation for Efficient Policy Evaluation in Sequential Decision Making

序贯决策中用于高效政策评估的最优处理分配

A/B testing is critical for modern technological companies to evaluate the effectiveness of newly developed products against standard baselines. This paper studies optimal designs that aim to maximize the amount of information obtained from online experiments to estimate treatment effects accurately. We propose three optimal allocation strategies in a dynamic setting where treatments are sequentially assigned over time. These strategies are designed to minimize the variance…

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Identification of time-varying counterfactual parameters in nonlinear panel models

非线性面板模型中时变反事实参数的识别

We develop a general framework for the identification of counterfactual parameters in a class of nonlinear semiparametric panel models with fixed effects and time effects. Our method applies to models for discrete outcomes (e.g., two-way fixed effects binary choice) or continuous outcomes (e.g., censored regression), with discrete or continuous regressors. Our results do not require parametric assumptions on the error terms or time-homogeneity on the outcome equation. Our…

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Regularised optimal self-transport is approximate Gaussian mixture maximum likelihood

正则化最优自传输近似高斯混合模型极大似然

We investigate the link between regularised self-transport problems and maximum likelihood estimation in Gaussian mixture models (GMM). This link suggests that self-transport followed by a clustering technique leads to principled estimators at a reasonable computational cost. Also, robustness, sparsity and stability properties of the optimal transport plan arguably make the regularised self-transport a statistical tool of choice for the GMM.

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Pooled Bewley Estimator of Long Run Relationships in Dynamic Heterogenous Panels

动态异质面板长期关系的合并 Bewley 估计量

Using a transformation of the autoregressive distributed lag model due to Bewley, a novel pooled Bewley (PB) estimator of long-run coefficients for dynamic panels with heterogeneous short-run dynamics is proposed. The PB estimator is directly comparable to the widely used Pooled Mean Group (PMG) estimator, and is shown to be consistent and asymptotically normal. Monte Carlo simulations show good small sample performance of PB compared to the existing estimators in the…

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Robust Parameter Estimation for the Lee-Carter Family: A Probabilistic Principal Component Approach

Lee–Carter 模型族的稳健参数估计:概率主成分方法

The well-known Lee-Carter model uses a bilinear form $\log(m_{x,t})=a_x+b_xk_t$ to represent the log mortality rate and has been widely researched and developed over the past thirty years. However, there has been little attention being paid to the robustness of the parameters against outliers, especially when estimating $b_x$. In response, we propose a robust estimation method for a wide family of Lee-Carter-type models, treating the problem as a Probabilistic Principal…

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High Precision Causal Model Evaluation with Conditional Randomization

条件随机化下的高精度因果模型评估

The gold standard for causal model evaluation involves comparing model predictions with true effects estimated from randomized controlled trials (RCT). However, RCTs are not always feasible or ethical to perform. In contrast, conditionally randomized experiments based on inverse probability weighting (IPW) offer a more realistic approach but may suffer from high estimation variance. To tackle this challenge and enhance causal model evaluation in real-world conditional…

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The use of restricted mean survival time to estimate treatment effect under model misspecification, a simulation study

模型误设下利用限制平均生存时间估计治疗效应:模拟研究

The use of the non-parametric Restricted Mean Survival Time endpoint (RMST) has grown in popularity as trialists look to analyse time-to-event outcomes without the restrictions of the proportional hazards assumption. In this paper, we evaluate the power and type I error rate of the parametric and non-parametric RMST estimators when treatment effect is explained by multiple covariates, including an interaction term. Utilising the RMST estimator in this way allows the combined…

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Sketching for Convex and Nonconvex Regularized Least Squares with Sharp Guarantees

凸与非凸正则化最小二乘的草图算法及其精确保证

Randomized algorithms are important for solving large-scale optimization problems. In this paper, we propose a fast sketching algorithm for least square problems regularized by convex or nonconvex regularization functions, Sketching for Regularized Optimization (SRO). Our SRO algorithm first generates a sketch of the original data matrix, then solves the sketched problem. Different from existing randomized algorithms, our algorithm handles general Frechet subdifferentiable…

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Causal inference with Machine Learning-Based Covariate Representation

基于机器学习协变量表示的因果推断

Utilizing covariate information has been a powerful approach to improve the efficiency and accuracy for causal inference, which support massive amount of randomized experiments run on data-driven enterprises. However, state-of-art approaches can become practically unreliable when the dimension of covariate increases to just 50, whereas experiments on large platforms can observe even higher dimension of covariate. We propose a machine-learning-assisted covariate…

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Phase transitions in nonparametric regressions

非参数回归中的相变

When the unknown regression function of a single variable is known to have derivatives up to the $(γ+1)$th order bounded in absolute values by a common constant everywhere or a.e. (i.e., $(γ+1)$th degree of smoothness), the minimax optimal rate of the mean integrated squared error (MISE) is stated as $\left(\frac{1}{n}\right)^{\frac{2γ+2}{2γ+3}}$ in the literature. This paper shows that: (i) if $n\leq\left(γ+1\right)^{2γ+3}$, the minimax optimal MISE rate is $\frac{\log n}{n\log(\log n)}$…

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