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NESTER: An Adaptive Neurosymbolic Method for Causal Effect Estimation

NESTER:用于因果效应估计的自适应神经符号方法

Causal effect estimation from observational data is a central problem in causal inference. Methods based on potential outcomes framework solve this problem by exploiting inductive biases and heuristics from causal inference. Each of these methods addresses a specific aspect of causal effect estimation, such as controlling propensity score, enforcing randomization, etc., by designing neural network (NN) architectures and regularizers. In this paper, we propose an adaptive…

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TAD-SIE: Sample Size Estimation for Clinical Randomized Controlled Trials using a Trend-Adaptive Design with a Synthetic-Intervention-Based Estimator

TAD-SIE:结合趋势自适应设计与合成干预估计的随机临床试验样本量确定

Phase-3 clinical trials provide the highest level of evidence on drug safety and effectiveness needed for market approval by implementing large randomized controlled trials (RCTs). However, 30-40% of these trials fail mainly because such studies have inadequate sample sizes, stemming from the inability to obtain accurate initial estimates of average treatment effect parameters. To remove this obstacle from the drug development cycle, we present a new algorithm called…

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Adaptive Estimation and Uniform Confidence Bands for Nonparametric Structural Functions and Elasticities

非参数结构函数与弹性的自适应估计及一致置信带

We introduce two data-driven procedures for optimal estimation and inference in nonparametric models using instrumental variables. The first is a data-driven choice of sieve dimension for a popular class of sieve two-stage least squares estimators. When implemented with this choice, estimators of both the structural function $h_0$ and its derivatives (such as elasticities) converge at the fastest possible (i.e., minimax) rates in sup-norm. The second is for constructing…

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Drift vs Shift: Decoupling Trends and Changepoint Analysis

漂移与突变:趋势和变点分析的分离

We introduce a new approach for decoupling trends (drift) and changepoints (shifts) in time series. Our locally adaptive model-based approach for robustly decoupling combines Bayesian trend filtering and machine learning based regularization. An over-parameterized Bayesian dynamic linear model (DLM) is first applied to characterize drift. Then a weighted penalized likelihood estimator is paired with the estimated DLM posterior distribution to identify shifts. We show how…

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On Rosenbaum's Rank-based Matching Estimator

论 Rosenbaum 基于秩的匹配估计量

In two influential contributions, Rosenbaum (2005, 2020) advocated for using the distances between component-wise ranks, instead of the original data values, to measure covariate similarity when constructing matching estimators of average treatment effects. While the intuitive benefits of using covariate ranks for matching estimation are apparent, there is no theoretical understanding of such procedures in the literature. We fill this gap by demonstrating that Rosenbaum's…

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Counterfactuals in factor models

因子模型中的反事实

We study a new model where the potential outcomes, corresponding to the values of a (possibly continuous) treatment, are linked through common factors. The factors can be estimated using a panel of regressors. We propose a procedure to estimate time-specific and unit-specific average marginal effects in this context. Our approach can be used either with high-dimensional time series or with large panels. It allows for treatment effects heterogenous across time and units and…

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ddml: Double/debiased machine learning in Stata

ddml:在 Stata 中实施双重/去偏机器学习

We introduce the package ddml for Double/Debiased Machine Learning (DDML) in Stata. Estimators of causal parameters for five different econometric models are supported, allowing for flexible estimation of causal effects of endogenous variables in settings with unknown functional forms and/or many exogenous variables. ddml is compatible with many existing supervised machine learning programs in Stata. We recommend using DDML in combination with stacking estimation which…

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A least distance estimator for a multivariate regression model using deep neural networks

基于深度神经网络的多变量回归最小距离估计

We propose a deep neural network (DNN) based least distance (LD) estimator (DNN-LD) for a multivariate regression problem, addressing the limitations of the conventional methods. Due to the flexibility of a DNN structure, both linear and nonlinear conditional mean functions can be easily modeled, and a multivariate regression model can be realized by simply adding extra nodes at the output layer. The proposed method is more efficient in capturing the dependency structure…

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Optimal Nonparametric Inference on Network Effects with Dependent Edges

边存在依赖时网络效应的最优非参数推断

Testing network effects in weighted directed networks is a foundational problem in econometrics, sociology, and psychology. Yet, the prevalent edge dependency poses a significant methodological challenge. Most existing methods are model-based and come with stringent assumptions, limiting their applicability. In response, we introduce a novel, fully nonparametric framework that requires only minimal regularity assumptions. While inspired by recent developments in $U$-statistic…

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Roughness Signature Functions

粗糙度特征函数

Inspired by the activity signature introduced by Todorov and Tauchen (2010), which was used to measure the activity of a semimartingale, this paper introduces the roughness signature function. The paper illustrates how it can be used to determine whether a discretely observed process is generated by a continuous process that is rougher than a Brownian motion, a pure-jump process, or a combination of the two. Further, if a continuous rough process is present, the function…

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Robustness Against Weak or Invalid Instruments: Exploring Nonlinear Treatment Models with Machine Learning

对弱工具变量或无效工具变量的稳健性:利用机器学习探索非线性治疗模型

We discuss causal inference for observational studies with possibly invalid instrumental variables. We propose a novel methodology called two-stage curvature identification (TSCI) by exploring the nonlinear treatment model with machine learning. {The first-stage machine learning enables improving the instrumental variable's strength and adjusting for different forms of violating the instrumental variable assumptions.} The success of TSCI requires the instrumental variable's…

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Disentangle Estimation of Causal Effects from Cross-Silo Data

跨数据孤岛的因果效应解耦估计

Estimating causal effects among different events is of great importance to critical fields such as drug development. Nevertheless, the data features associated with events may be distributed across various silos and remain private within respective parties, impeding direct information exchange between them. This, in turn, can result in biased estimations of local causal effects, which rely on the characteristics of only a subset of the covariates. To tackle this challenge,…

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Residual Importance Weighted Transfer Learning For High-dimensional Linear Regression

残差重要性加权的高维线性回归迁移学习

Transfer learning is an emerging paradigm for leveraging multiple sources to improve the statistical inference on a single target. In this paper, we propose a novel approach named residual importance weighted transfer learning (RIW-TL) for high-dimensional linear models built on penalized likelihood. Compared to existing methods such as Trans-Lasso that selects sources in an all-in-all-out manner, RIW-TL includes samples via importance weighting and thus may permit more…

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A note on the prediction error of principal component regression in high dimensions

高维主成分回归的预测误差注记

We analyze the prediction error of principal component regression (PCR) and prove high probability bounds for the corresponding squared risk conditional on the design. Our first main result shows that PCR performs comparably to the oracle method obtained by replacing empirical principal components by their population counterparts, provided that an effective rank condition holds. On the other hand, if the latter condition is violated, then empirical eigenvalues start to have…

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Adaptive learning of density ratios in RKHS

RKHS 中密度比的自适应学习

Estimating the ratio of two probability densities from finitely many observations of the densities is a central problem in machine learning and statistics with applications in two-sample testing, divergence estimation, generative modeling, covariate shift adaptation, conditional density estimation, and novelty detection. In this work, we analyze a large class of density ratio estimation methods that minimize a regularized Bregman divergence between the true density ratio and…

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Estimating and Mitigating the Congestion Effect of Curbside Pick-ups and Drop-offs: A Causal Inference Approach

路边上下客拥堵效应的估计与缓解:因果推断方法

Curb space is one of the busiest areas in urban road networks. Especially in recent years, the rapid increase of ride-hailing trips and commercial deliveries has induced massive pick-ups/drop-offs (PUDOs), which occupy the limited curb space that was designed and built decades ago. These PUDOs could jam curbside utilization and disturb the mainline traffic flow, evidently leading to significant negative societal externalities. However, there is a lack of an analytical…

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The Contextual Lasso: Sparse Linear Models via Deep Neural Networks

情境套索:通过深度神经网络实现稀疏线性模型

Sparse linear models are one of several core tools for interpretable machine learning, a field of emerging importance as predictive models permeate decision-making in many domains. Unfortunately, sparse linear models are far less flexible as functions of their input features than black-box models like deep neural networks. With this capability gap in mind, we study a not-uncommon situation where the input features dichotomize into two groups: explanatory features, which are…

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Bayesian Effect Selection in Additive Models with an Application to Time-to-Event Data

可加模型中的贝叶斯效应选择及其在生存数据中的应用

Accurately selecting and estimating smooth functional effects in additive models with potentially many functions is a challenging task. We introduce a novel Demmler-Reinsch basis expansion to model the functional effects that allows us to orthogonally decompose an effect into its linear and nonlinear parts. We show that our representation allows to consistently estimate both parts as opposed to commonly employed mixed model representations. Equipping the reparameterized…

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Transfer Learning for Causal Effect Estimation

用于因果效应估计的迁移学习

We present a Transfer Causal Learning (TCL) framework when target and source domains share the same covariate/feature spaces, aiming to improve causal effect estimation accuracy in limited data. Limited data is very common in medical applications, where some rare medical conditions, such as sepsis, are of interest. Our proposed method, named \texttt{$\ell_1$-TCL}, incorporates $\ell_1$ regularized TL for nuisance models (e.g., propensity score model); the TL estimator of the…

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How industrial clusters influence the growth of the regional GDP: A spatial-approach

产业集群如何影响地区 GDP 增长:空间计量视角

In this paper, we employ spatial econometric methods to analyze panel data from German NUTS 3 regions. Our goal is to gain a deeper understanding of the significance and interdependence of industry clusters in shaping the dynamics of GDP. To achieve a more nuanced spatial differentiation, we introduce indicator matrices for each industry sector which allows for extending the spatial Durbin model to a new version of it. This approach is essential due to both the economic…

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Extrapolation of Relative Treatment Effects using Change-point Survival Models

利用变点生存模型外推相对治疗效应

Introduction: Modelling of relative treatment effects is an important aspect to consider when extrapolating the long-term survival outcomes of treatments. Flexible parametric models offer the ability to accurately model the observed data, however, the extrapolated relative treatment effects and subsequent survival function may lack face validity. Methods: We investigate the ability of change-point survival models to estimate changes in the relative treatment effects,…

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Universality in block dependent linear models with applications to nonparametric regression

块依赖线性模型的普适性及其在非参数回归中的应用

Over the past decade, characterizing the exact asymptotic risk of regularized estimators in high-dimensional regression has emerged as a popular line of work. This literature considers the proportional asymptotics framework, where the number of features and samples both diverge, at a rate proportional to each other. Substantial work in this area relies on Gaussianity assumptions on the observed covariates. Further, these studies often assume the design entries to be…

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Post-Selection Inference for the Cox Model with Interval-Censored Data

区间删失数据下Cox模型的后选择推断

We develop a post-selection inference method for the Cox proportional hazards model with interval-censored data, which provides asymptotically valid p-values and confidence intervals conditional on the model selected by lasso. The method is based on a pivotal quantity that is shown to converge to a uniform distribution under local alternatives. The proof can be adapted to many other regression models, which is illustrated by the extension to generalized linear models and the…

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Unconditional Quantile Partial Effects via Conditional Quantile Regression

通过条件分位数回归估计无条件分位数偏效应

This paper develops a semi-parametric procedure for estimation of unconditional quantile partial effects using quantile regression coefficients. The estimator is based on an identification result showing that, for continuous covariates, unconditional quantile effects are a weighted average of conditional ones at particular quantile levels that depend on the covariates. We propose a two-step estimator for the unconditional effects where in the first step one estimates a…

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