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Inference for Heteroskedastic PCA with Missing Data

缺失数据下异方差主成分分析的统计推断

This paper studies how to construct confidence regions for principal component analysis (PCA) in high dimension, a problem that has been vastly under-explored. While computing measures of uncertainty for nonlinear/nonconvex estimators is in general difficult in high dimension, the challenge is further compounded by the prevalent presence of missing data and heteroskedastic noise. We propose a novel approach to performing valid inference on the principal subspace under a…

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Difference-based covariance matrix estimate in time series nonparametric regression with applications to specification tests

时间序列非参数回归中基于差分的协方差矩阵估计及其设定检验应用

Long-run covariance matrix estimation is the building block of time series inference. The corresponding difference-based estimator, which avoids detrending, has attracted considerable interest due to its robustness to both smooth and abrupt structural breaks and its competitive finite sample performance. However, existing methods mainly focus on estimators for the univariate process while their direct and multivariate extensions for most linear models are asymptotically…

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Bayesian Geographically Weighted Regression using Fused Lasso Prior

基于融合Lasso先验的贝叶斯地理加权回归

A main purpose of spatial data analysis is to predict the objective variable for the unobserved locations. Although Geographically Weighted Regression (GWR) is often used for this purpose, estimation instability proves to be an issue. To address this issue, Bayesian Geographically Weighted Regression (BGWR) has been proposed. In BGWR, by setting the same prior distribution for all locations, the coefficients' estimation stability is improved. However, when observation…

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Quantile Outcome Adaptive Lasso: Covariate Selection for Inverse Probability Weighting Estimator of Quantile Treatment Effects

分位数结果自适应 Lasso:分位数处理效应逆概率加权估计的协变量选择

When using the propensity score method to estimate the treatment effects, it is important to select the covariates to be included in the propensity score model. The inclusion of covariates unrelated to the outcome in the propensity score model led to bias and large variance in the estimator of treatment effects. Many data-driven covariate selection methods have been proposed for selecting covariates related to outcomes. However, most of them assume an average treatment…

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Advancing Counterfactual Inference through Nonlinear Quantile Regression

通过非线性分位数回归推进反事实推断

The capacity to address counterfactual "what if" inquiries is crucial for understanding and making use of causal influences. Traditional counterfactual inference, under Pearls' counterfactual framework, typically depends on having access to or estimating a structural causal model. Yet, in practice, this causal model is often unknown and might be challenging to identify. Hence, this paper aims to perform reliable counterfactual inference based solely on observational data and…

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Combined Quantile Forecasting for High-Dimensional Non-Gaussian Data

高维非高斯数据的组合分位数预测

This study proposes a novel method for forecasting a scalar variable based on high-dimensional predictors that is applicable to various data distributions. In the literature, one of the popular approaches for forecasting with many predictors is to use factor models. However, these traditional methods are ineffective when the data exhibit non-Gaussian characteristics such as skewness or heavy tails. In this study, we newly utilize a quantile factor model to extract quantile…

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An Online Bootstrap for Time Series

时间序列的在线自助法

Resampling methods such as the bootstrap have proven invaluable in the field of machine learning. However, the applicability of traditional bootstrap methods is limited when dealing with large streams of dependent data, such as time series or spatially correlated observations. In this paper, we propose a novel bootstrap method that is designed to account for data dependencies and can be executed online, making it particularly suitable for real-time applications. This method…

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Doubly Robust Identification of Causal Effects of a Continuous Treatment using Discrete Instruments

利用离散工具变量双重稳健识别连续处理的因果效应

Many empirical applications estimate causal effects of a continuous endogenous variable (treatment) using a binary instrument. Estimation is typically done through linear 2SLS. This approach requires a mean treatment change and causal interpretation requires the LATE-type monotonicity in the first stage. An alternative approach is to explore distributional changes in the treatment, where the first-stage restriction is treatment rank similarity. We propose causal estimands…

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Tree-Guided Rare Feature Selection and Logic Aggregation with Electronic Health Records Data

树引导的稀有特征选择与逻辑聚合:基于电子健康记录数据

Statistical learning with a large number of rare binary features is commonly encountered in analyzing electronic health records (EHR) data, especially in the modeling of disease onset with prior medical diagnoses and procedures. Dealing with the resulting highly sparse and large-scale binary feature matrix is notoriously challenging as conventional methods may suffer from a lack of power in testing and inconsistency in model fitting while machine learning methods may suffer…

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Robust Evaluation of Longitudinal Surrogate Markers with Censored Data

删失数据下纵向替代标志物的稳健评估

The development of statistical methods to evaluate surrogate markers is an active area of research. In many clinical settings, the surrogate marker is not simply a single measurement but is instead a longitudinal trajectory of measurements over time, e.g., fasting plasma glucose measured every 6 months for 3 years. In general, available methods developed for the single-surrogate setting cannot accommodate a longitudinal surrogate marker. Furthermore, many of the methods have…

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Failures and Successes of Cross-Validation for Early-Stopped Gradient Descent

早停梯度下降中交叉验证的失败与成功

We analyze the statistical properties of generalized cross-validation (GCV) and leave-one-out cross-validation (LOOCV) applied to early-stopped gradient descent (GD) in high-dimensional least squares regression. We prove that GCV is generically inconsistent as an estimator of the prediction risk of early-stopped GD, even for a well-specified linear model with isotropic features. In contrast, we show that LOOCV converges uniformly along the GD trajectory to the prediction…

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Nonparametric assessment of regimen response curve estimators

治疗方案响应曲线估计量的非参数评估

Marginal structural models have been widely used in causal inference to estimate mean outcomes under either a static or a prespecified set of treatment decision rules. This approach requires imposing a working model for the mean outcome given a sequence of treatments and possibly baseline covariates. In this paper, we introduce a dynamic marginal structural model that can be used to estimate an optimal decision rule within a class of parametric rules. Specifically, we will…

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Fast Algorithms for Quantile Regression with Selection

含样本选择的分位数回归快速算法

This paper addresses computational challenges in estimating Quantile Regression with Selection (QRS). The estimation of the parameters that model self-selection requires the estimation of the entire quantile process several times. Moreover, closed-form expressions of the asymptotic variance are too cumbersome, making the bootstrap more convenient to perform inference. Taking advantage of recent advancements in the estimation of quantile regression, along with some specific…

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Penalized Generative Variable Selection

惩罚生成式变量选择

Deep networks are increasingly applied to a wide variety of data, including data with high-dimensional predictors. In such analysis, variable selection can be needed along with estimation/model building. Many of the existing deep network studies that incorporate variable selection have been limited to methodological and numerical developments. In this study, we consider modeling/estimation using the conditional Wasserstein Generative Adversarial networks. Group Lasso…

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Estimation with Pairwise Observations

基于成对观测的估计

The paper introduces a new estimation method for the standard linear regression model. The procedure is not driven by the optimisation of any objective function rather, it is a simple weighted average of slopes from observation pairs. The paper shows that such estimator is consistent for carefully selected weights. Other properties, such as asymptotic distributions, have also been derived to facilitate valid statistical inference. Unlike traditional methods, such as Least…

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Estimating Stochastic Block Models in the Presence of Covariates

含协变量的随机块模型估计

In the standard stochastic block model for networks, the probability of a connection between two nodes, often referred to as the edge probability, depends on the unobserved communities each of these nodes belongs to. We consider a flexible framework in which each edge probability, together with the probability of community assignment, are also impacted by observed covariates. We propose a computationally tractable two-step procedure to estimate the conditional edge…

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The role of randomization inference in unraveling individual treatment effects in early phase vaccine trials

早期疫苗试验中个体处理效应的随机化推断

Randomization inference is a powerful tool in early phase vaccine trials when estimating the causal effect of a regimen against a placebo or another regimen. Randomization-based inference often focuses on testing either Fisher's sharp null hypothesis of no treatment effect for any participant or Neyman's weak null hypothesis of no sample average treatment effect. Many recent efforts have explored conducting exact randomization-based inference for other summaries of the…

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Simulation-based transition density approximation for the inference of SDE models

基于模拟的转移密度近似与随机微分方程模型推断

Stochastic Differential Equations (SDEs) serve as a powerful modeling tool in various scientific domains, including systems science, engineering, and ecological science. While the specific form of SDEs is typically known for a given problem, certain model parameters remain unknown. Efficiently inferring these unknown parameters based on observations of the state in discrete time series represents a vital practical subject. The challenge arises in nonlinear SDEs, where…

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Transfer Learning with Large-Scale Quantile Regression

大规模分位数回归中的迁移学习

Quantile regression is increasingly encountered in modern big data applications due to its robustness and flexibility. We consider the scenario of learning the conditional quantiles of a specific target population when the available data may go beyond the target and be supplemented from other sources that possibly share similarities with the target. A crucial question is how to properly distinguish and utilize useful information from other sources to improve the quantile…

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Impact of Physical Activity on Quality of Life During Pregnancy: A Causal ML Approach

孕期身体活动对生活质量的影响:因果机器学习方法

The concept of Quality of Life (QoL) refers to a holistic measurement of an individual's well-being, incorporating psychological and social aspects. Pregnant women, especially those with obesity and stress, often experience lower QoL. Physical activity (PA) has shown the potential to enhance the QoL. However, pregnant women who are overweight and obese rarely meet the recommended level of PA. Studies have investigated the relationship between PA and QoL during pregnancy…

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An Interpretable and Efficient Infinite-Order Vector Autoregressive Model for High-Dimensional Time Series

用于高维时间序列的可解释且高效的无限阶向量自回归模型

As a special infinite-order vector autoregressive (VAR) model, the vector autoregressive moving average (VARMA) model can capture much richer temporal patterns than the widely used finite-order VAR model. However, its practicality has long been hindered by its non-identifiability, computational intractability, and difficulty of interpretation, especially for high-dimensional time series. This paper proposes a novel sparse infinite-order VAR model for high-dimensional time…

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GENIUS-MAWII: For Robust Mendelian Randomization with Many Weak Invalid Instruments

GENIUS-MAWII:应对大量弱且无效工具变量的稳健孟德尔随机化

Mendelian randomization (MR) has become a popular approach to study causal effects by using genetic variants as instrumental variables. We propose a new MR method, GENIUS-MAWII, which simultaneously addresses the two salient phenomena that adversely affect MR analyses: many weak instruments and widespread horizontal pleiotropy. Similar to MR GENIUS (Tchetgen Tchetgen et al., 2021), we achieve identification of the treatment effect by leveraging heteroscedasticity of the…

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Local moment matching with Erlang mixtures under automatic roughness penalization

自动粗糙度惩罚下的Erlang混合局部矩匹配

We consider the class of Erlang mixtures for the task of density estimation on the positive real line when the only available information is given as local moments, a histogram with potentially higher order moments in some bins. By construction, the obtained moment problem is ill-posed and requires regularization. Several penalties can be used for such a task, such as a lasso penalty for sparsity of the representation, but we focus here on a simplified roughness penalty from…

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Mean-preserving rounding integer-valued ARMA models

基于保均值随机舍入的整数值 ARMA 模型

In the past four decades, research on count time series has made significant progress, but research on $\mathbb{Z}$-valued time series is relatively rare. Existing $\mathbb{Z}$-valued models are mainly of autoregressive structure, where the use of the rounding operator is very natural. Because of the discontinuity of the rounding operator, the formulation of the corresponding model identifiability conditions and the computation of parameter estimators need special attention.…

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