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多阶段学习与双重稳健深度神经网络的因果推断AI 解读

Deep neural networks (DNNs) have demonstrated remarkable empirical performance in large-scale supervised learning problems, particularly in scenarios where both the sample size $n$ and the dimension of covariates $p$ are large. This study delves into the application of DNNs across a wide spectrum of intricate causal inference tasks, where direct estimation falls short and necessitates multi-stage learning. Examples include estimating the conditional average treatment effect…

使用新型集成方法稳健估计条件平均处理效应AI 解读

The estimation of Conditional Average Treatment Effects (CATE) is crucial for understanding the heterogeneity of treatment effects in clinical trials. We evaluate the performance of common methods, including causal forests and various meta-learners, across a diverse set of scenarios, revealing that each of the methods struggles in one or more of the tested scenarios. Given the inherent uncertainty of the data-generating process in real-life scenarios, the robustness of a…

通过最优传输自动校正异常值AI 解读

In this paper, we propose a novel conceptual framework to detect outliers using optimal transport with a concave cost function. Conventional outlier detection approaches typically use a two-stage procedure: first, outliers are detected and removed, and then estimation is performed on the cleaned data. However, this approach does not inform outlier removal with the estimation task, leaving room for improvement. To address this limitation, we propose an automatic outlier…

从低层级测量直接估计高层级相关性：基因通路与蛋白质组应用AI 解读

This paper tackles the challenge of estimating correlations between higher-level biological variables (e.g., proteins and gene pathways) when only lower-level measurements are directly observed (e.g., peptides and individual genes). Existing methods typically aggregate lower-level data into higher-level variables and then estimate correlations based on the aggregated data. However, different data aggregation methods can yield varying correlation estimates as they target…

使用时变工具变量的两阶段最小二乘：二型糖尿病治疗强化评估AI 解读

As longitudinal data becomes more available in many settings, policy makers are increasingly interested in the effect of time-varying treatments (e.g. sustained treatment strategies). In settings such as this, the preferred analysis techniques are the g-methods, however these require the untestable assumption of no unmeasured confounding. Instrumental variable analyses can minimise bias through unmeasured confounding. Of these methods, the Two Stage Least Squares technique…

学习线性算子：无穷维回归作为良态非紧逆问题AI 解读

We consider the problem of learning a linear operator $θ$ between two Hilbert spaces from empirical observations, which we interpret as least squares regression in infinite dimensions. We show that this goal can be reformulated as an inverse problem for $θ$ with the feature that its forward operator is generally non-compact (even if $θ$ is assumed to be compact or of $p$-Schatten class). However, we prove that, in terms of spectral properties and regularisation theory, this…

特定因子模型样本相关矩阵有界与发散特征值的渐近位置及成分保留规则AI 解读

Let the dimension $N$ of data and the sample size $T$ tend to $\infty$ with $N/T \to c > 0$. The spectral properties of a sample correlation matrix $\mathbf{C}$ and a sample covariance matrix $\mathbf{S}$ are asymptotically equal whenever the population correlation matrix $\mathbf{R}$ is bounded (El Karoui 2009). We demonstrate this also for general linear models for unbounded $\mathbf{R}$, by examining the behavior of the singular values of multiplicatively perturbed…

稀疏内在得分下的协变量辅助对象排序AI 解读

This paper addresses the item ranking problem with associate covariates, focusing on scenarios where the preference scores can not be fully explained by covariates, and the remaining intrinsic scores, are sparse. Specifically, we extend the pioneering Bradley-Terry-Luce (BTL) model by incorporating covariate information and considering sparse individual intrinsic scores. Our work introduces novel model identification conditions and examines the regularized penalized Maximum…

聚合贝叶斯因果森林：分层数据的灵活因果推断AI 解读

This paper introduces aggregate Bayesian Causal Forests (aBCF), a new Bayesian model for causal inference using aggregated data. Aggregated data are common in policy evaluations where we observe individuals such as students, but participation in an intervention is determined at a higher level of aggregation, such as schools implementing a curriculum. Interventions often have millions of individuals but far fewer higher-level units, making aggregation computationally…

主成分因子置信区域构造中的特异成分横截面相关处理AI 解读

In this paper, we propose a computationally simple estimator of the asymptotic covariance matrix of the Principal Components (PC) factors valid in the presence of cross-correlated idiosyncratic components. The proposed estimator of the asymptotic Mean Square Error (MSE) of PC factors is based on adaptive thresholding the sample covariances of the id iosyncratic residuals with the threshold based on their individual variances. We compare the nite sample performance of…

高维函数型时间序列的因子建模AI 解读

Many economic and scientific problems involve the analysis of high-dimensional functional time series, where the number of functional variables $p$ diverges as the number of serially dependent observations $n$ increases. In this paper, we present a novel functional factor model for high-dimensional functional time series that maintains and makes use of the functional and dynamic structure to achieve great dimension reduction and find the latent factor structure. To estimate…

集群随机试验中用混合效应模型检验处理效应异质性的第一类错误风险AI 解读

Evaluating heterogeneity of treatment effects (HTE) across subgroups is common in both randomized trials and observational studies. Although several statistical challenges of HTE analyses including low statistical power and multiple comparisons are widely acknowledged, issues arising for clustered data, including cluster randomized trials (CRTs), have received less attention. Notably, the potential for model misspecification is increased given the complex clustering…

基于替代终点的临时批准因果路线图AI 解读

For many rare diseases with no approved preventive interventions, promising interventions exist, yet it has been difficult to conduct a pivotal phase 3 trial that could provide direct evidence demonstrating a beneficial effect on the target disease outcome. When a promising putative surrogate endpoint(s) for the target outcome is available, surrogate-based provisional approval of an intervention may be pursued. We apply the Causal Roadmap rubric to define a surrogate…

如何在信息借用下向进行中的篮式试验加入新篮AI 解读

Basket trials test a single therapeutic treatment on several patient populations under one master protocol. A desirable adaptive design feature in these studies may be the incorporation of new baskets to an ongoing study. Limited basket sample sizes can cause issues in power and precision of treatment effect estimates which could be amplified in added baskets due to the shortened recruitment time. While various Bayesian information borrowing techniques have been introduced…

面向一般响应类型的模型化因果特征选择AI 解读

Discovering causal relationships from observational data is a fundamental yet challenging task. Invariant causal prediction (ICP, Peters et al., 2016) is a method for causal feature selection which requires data from heterogeneous settings and exploits that causal models are invariant. ICP has been extended to general additive noise models and to nonparametric settings using conditional independence tests. However, the latter often suffer from low power (or poor type I error…

高维时间序列的动态矩阵因子模型AI 解读

Matrix time series, which consist of matrix-valued data observed over time, are prevalent in various fields such as economics, finance, and engineering. Such matrix time series data are often observed in high dimensions. Matrix factor models are employed to reduce the dimensionality of such data, but they lack the capability to make predictions without specified dynamics in the latent factor process. To address this issue, we propose a two-component dynamic matrix factor…

合成控制的贝叶斯与频率学派推断AI 解读

The synthetic control method has become a widely popular tool to estimate causal effects with observational data. Despite this, inference for synthetic control methods remains challenging. Often, inferential results rely on linear factor model data generating processes. In this paper, we characterize the conditions on the factor model primitives (the factor loadings) for which the statistical risk minimizers are synthetic controls (in the simplex). Then, we propose a…

用于插补与个体化推断的凸化匹配方法AI 解读

We introduce a new convexified matching method for missing value imputation and individualized inference inspired by computational optimal transport. Our method integrates favorable features from mainstream imputation approaches: optimal matching, regression imputation, and synthetic control. We impute counterfactual outcomes based on convex combinations of observed outcomes, defined based on an optimal coupling between the treated and control data sets. The optimal coupling…

用于因果效应识别的快速代理实验设计AI 解读

Identifying causal effects is a key problem of interest across many disciplines. The two long-standing approaches to estimate causal effects are observational and experimental (randomized) studies. Observational studies can suffer from unmeasured confounding, which may render the causal effects unidentifiable. On the other hand, direct experiments on the target variable may be too costly or even infeasible to conduct. A middle ground between these two approaches is to…

非平稳重尾时间序列的统计推断AI 解读

We consider the problem of inference for non-stationary time series with heavy-tailed error distribution. Under a time-varying linear process framework we show that there exists a suitable local approximation by a stationary process with heavy-tails. This enable us to introduce a local approximation-based estimator which estimates consistently time-varying parameters of the model at hand. To develop a robust method, we also suggest a self-weighing scheme which is shown to…

自由节点样条估计与粗糙度正则化的函数型数据分析AI 解读

In the era of big data, an ever-growing volume of information is recorded, either continuously over time or sporadically, at distinct time intervals. Functional Data Analysis (FDA) stands at the cutting edge of this data revolution, offering a powerful framework for handling and extracting meaningful insights from such complex datasets. The currently proposed FDA me\-thods can often encounter challenges, especially when dealing with curves of varying shapes. This can largely…

重尾结果下协变量自适应随机化的处理效应估计AI 解读

Randomized experiments are the gold standard for investigating causal relationships, with comparisons of potential outcomes under different treatment groups used to estimate treatment effects. However, outcomes with heavy-tailed distributions pose significant challenges to traditional statistical approaches. While recent studies have explored these issues under simple randomization, their application in more complex randomization designs, such as stratified randomization or…

Engression：分布回归视角下的外推AI 解读

Distributional regression aims to estimate the full conditional distribution of a target variable, given covariates. Popular methods include linear and tree-ensemble based quantile regression. We propose a neural network-based distributional regression methodology called `engression'. An engression model is generative in the sense that we can sample from the fitted conditional distribution and is also suitable for high-dimensional outcomes. Furthermore, we find that…

核岭 Riesz 表示元：泛化、误设与反事实有效维度AI 解读

Kernel balancing weights provide confidence intervals for average treatment effects, based on the idea of balancing covariates for the treated group and untreated group in feature space, often with ridge regularization. Previous works on the classical kernel ridge balancing weights have certain limitations: (i) not articulating generalization error for the balancing weights, (ii) typically requiring correct specification of features, and (iii) justifying Gaussian…