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整合多项多变量结局观察研究的因果元分析AI 解读

Integrating multiple observational studies to make unconfounded causal or descriptive comparisons of group potential outcomes in a large natural population is challenging. Moreover, retrospective cohorts, being convenience samples, are usually unrepresentative of the natural population of interest and have groups with unbalanced covariates. We propose a general covariate-balancing framework based on pseudo-populations that extends established weighting methods to the…

前向正交离差 GMM 与大样本偏差的消除AI 解读

It is well known that generalized method of moments (GMM) estimators of dynamic panel data regressions can have significant bias when the number of time periods ($T$) is not small compared to the number of cross-sectional units ($n$). The bias is attributed to the use of many instrumental variables. This paper shows that if the maximum number of instrumental variables used in a period increases with $T$ at a rate slower than $T^{1/2}$, then GMM estimators that exploit the…

离散采样周期性长记忆过程的滤波型估计AI 解读

The generalized filtered method of moments was developed in the recent papers by Alomari et al., 2020, and Ayache et al., 2022. It used functional data obtained from continuously sampled cyclic long-memory stochastic processes to simultaneously estimate their parameters. However, the majority of applications deal with discretely sampled processes or time series. This paper extends the approach to accommodate discrete-time scenarios. It proves that the new discrete estimates…

条件相对效应可迁移假设下的因果推断AI 解读

When extending inferences from a randomized trial to a new target population, the transportability condition for conditional difference effect measures is invoked to identify the marginal causal mean difference in the target population. However, many clinical investigators believe that conditional relative effect measures are more likely to be "transportable" between populations. Here, we examine the identification and estimation of the marginal counterfactual mean…

主层因果效应的可迁移性AI 解读

Recent research in causal inference has made important progress in addressing challenges to the external validity of trial findings. Such methods weight trial participant data to more closely resemble the distribution of effect-modifying covariates in a well-defined target population. In the presence of participant non-adherence to study medication, these methods effectively transport an intention-to-treat effect that averages over heterogeneous compliance behaviors. In this…

研发支出的即时预测：机器学习方法AI 解读

Macroeconomic data are crucial for monitoring countries' performance and driving policy. However, traditional data acquisition processes are slow, subject to delays, and performed at a low frequency. We address this 'ragged-edge' problem with a two-step framework. The first step is a supervised learning model predicting observed low-frequency figures. We propose a neural-network-based nowcasting model that exploits mixed-frequency, high-dimensional data. The second step uses…

用收缩方法估计生存终点随机试验中重叠亚组的治疗效应AI 解读

In randomized controlled trials, forest plots are frequently used to investigate the homogeneity of treatment effect estimates in subgroups. However, the interpretation of subgroup-specific treatment effect estimates requires great care due to the smaller sample size of subgroups and the large number of investigated subgroups. Bayesian shrinkage methods have been proposed to address these issues, but they often focus on disjoint subgroups while subgroups displayed in forest…

用于高维协方差矩阵的层级 DCC-HEAVY 模型AI 解读

We introduce a HD DCC-HEAVY class of hierarchical-type factor models for high-dimensional covariance matrices, employing the realized measures built from higher-frequency data. The modelling approach features straightforward estimation and forecasting schemes, independent of the cross-sectional dimension of the assets under consideration, and accounts for sophisticated asymmetric dynamics in the covariances. Empirical analyses suggest that the HD DCC-HEAVY models have a…

比较分组生存数据的限制平均生存时间：贝叶斯非参数方法AI 解读

Comparing survival experiences of different groups of data is an important issue in several applied problems. A typical example is where one wishes to investigate treatment effects. Here we propose a new Bayesian approach based on restricted mean survival times (RMST). A nonparametric prior is specified for the underlying survival functions: this extends the standard univariate neutral to the right processes to a multivariate setting and induces a prior for the RMST's. We…

多元Hawkes过程路径的ERM-Lasso分类算法AI 解读

We are interested in the problem of classifying Multivariate Hawkes Processes (MHP) paths coming from several classes. MHP form a versatile family of point processes that models interactions between connected individuals within a network. In this paper, the classes are discriminated by the exogenous intensity vector and the adjacency matrix, which encodes the strength of the interactions. The observed learning data consist of labeled repeated and independent paths on a fixed…

粗糙波动率的非参数检验AI 解读

We develop a nonparametric test for deciding whether volatility of an asset follows a standard semimartingale process, with paths of finite quadratic variation, or a rough process with paths of infinite quadratic variation. The test utilizes the fact that volatility is rough if and only if volatility increments are negatively autocorrelated at high frequencies. It is based on the sample autocovariance of increments of spot volatility estimates computed from high-frequency…

必要与充分因果概率的半参数有效推断AI 解读

Causal attribution, which aims to explain why events or behaviors occur, is crucial in causal inference and enhances our understanding of cause-and-effect relationships in scientific research. The probabilities of necessary causation (PN) and sufficient causation (PS) are two of the most common quantities for attribution in causal inference. While many works have explored the identification or bounds of PN and PS, efficient estimation remains unaddressed. To fill this gap,…

通过高维贝叶斯协整构建低波动股票组合AI 解读

We employ a Bayesian modelling technique for high dimensional cointegration estimation to construct low volatility portfolios from a large number of stocks. The proposed Bayesian framework effectively identifies sparse and important cointegration relationships amongst large baskets of stocks across various asset spaces, resulting in portfolios with reduced volatility. Such cointegration relationships persist well over the out-of-sample testing time, providing practical…

UTOPIA：可训练的最优预测区间聚合AI 解读

Uncertainty quantification in prediction presents a compelling challenge with vast applications across various domains, including biomedical science, economics, and weather forecasting. There exists a wide array of methods for constructing prediction intervals, such as quantile regression and conformal prediction. However, practitioners often face the challenge of selecting the most suitable method for a specific real-world data problem. In response to this dilemma, we…

存在混杂的加性噪声模型中平均因果效应的识别AI 解读

Additive noise models (ANMs) are an important setting studied in causal inference. Most of the existing works on ANMs assume causal sufficiency, i.e., there are no unobserved confounders. This paper focuses on confounded ANMs, where a set of treatment variables and a target variable are affected by an unobserved confounder that follows a multivariate Gaussian distribution. We introduce a novel approach for estimating the average causal effects (ACEs) of any subset of the…

稀疏异方差贝叶斯高维回归量化卒中失语症严重程度的预测不确定性AI 解读

Sparse linear regression methods for high-dimensional data commonly assume that residuals have constant variance, which can be violated in practice. For example, Aphasia Quotient (AQ) is a critical measure of language impairment and informs treatment decisions, but it is challenging to measure in stroke patients. It is of interest to use high-resolution T2 neuroimages of brain damage to predict AQ. However, sparse regression models show marked evidence of heteroscedastic…

时变处理的反事实生成模型AI 解读

Estimating the counterfactual outcome of treatment is essential for decision-making in public health and clinical science, among others. Often, treatments are administered in a sequential, time-varying manner, leading to an exponentially increased number of possible counterfactual outcomes. Furthermore, in modern applications, the outcomes are high-dimensional and conventional average treatment effect estimation fails to capture disparities in individuals. To tackle these…

通过相关系数多重检验正则化股票收益协方差矩阵AI 解读

This paper develops a large-scale inference approach for the regularization of stock return covariance matrices. The framework allows for the presence of heavy tails and multivariate GARCH-type effects of unknown form among the stock returns. The approach involves simultaneous testing of all pairwise correlations, followed by setting non-statistically significant elements to zero. This adaptive thresholding is achieved through sign-based Monte Carlo resampling within…

结合不可信数据的元分析AI 解读

[See paper for full abstract] Meta-analysis is a crucial tool for answering scientific questions. It is usually conducted on a relatively small amount of ``trusted'' data -- ideally from randomized, controlled trials -- which allow causal effects to be reliably estimated with minimal assumptions. We show how to answer causal questions much more precisely by making two changes. First, we incorporate untrusted data drawn from large observational databases, related scientific…

存在部分无效工具变量时双向孟德尔随机化的识别与估计AI 解读

We consider the challenging problem of estimating causal effects from purely observational data in the bi-directional Mendelian randomization (MR), where some invalid instruments, as well as unmeasured confounding, usually exist. To address this problem, most existing methods attempt to find proper valid instrumental variables (IVs) for the target causal effect by expert knowledge or by assuming that the causal model is a one-directional MR model. As such, in this paper, we…

生存结局序贯试验模拟的推断：夹心方差、Bootstrap 与 Jackknife 比较AI 解读

Sequential trial emulation (STE) is an approach to estimating causal treatment effects by emulating a sequence of target trials from observational data. In STE, inverse probability weighting is commonly utilised to address time-varying confounding and/or dependent censoring. Then structural models for potential outcomes are applied to the weighted data to estimate treatment effects. For inference, the simple sandwich variance estimator is popular but conservative, while…

利用混杂因素替代变量估计因果暴露反应曲线：空气污染与儿童健康AI 解读

In this paper, we undertake a case study to estimate a causal exposure-response function (ERF) for long-term exposure to fine particulate matter (PM$_{2.5}$) and respiratory hospitalizations in socioeconomically disadvantaged children using nationwide Medicaid claims data. These data present specific challenges. First, family income-based Medicaid eligibility criteria for children differ by state, creating socioeconomically distinct populations and leading to clustered data.…

异质性因果效应的最大熵估计AI 解读

For the purpose of causal inference we employ a stochastic model of the data generating process, utilizing individual propensity probabilities for the treatment, and also individual and counterfactual prognosis probabilities for the outcome. We assume a generalized version of the stable unit treatment value assumption, but we do not assume any version of strongly ignorable treatment assignment. Instead of conducting a sensitivity analysis, we utilize the principle of maximum…

多阶段框架下上游油气行业甲烷排放估计AI 解读

Measurement-based methane inventories, which involve surveying oil and gas facilities and compiling data to estimate methane emissions, are becoming the gold standard for quantifying emissions. However, there is a current lack of statistical guidance for the design and analysis of such surveys. The only existing method is a Monte Carlo procedure which is difficult to interpret, computationally intensive, and lacks available open-source code for its implementation. We provide…