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Safe Policy Learning under Regression Discontinuity Designs with Multiple Cutoffs

多阈值断点回归设计下的安全政策学习

The regression discontinuity (RD) design is widely used for program evaluation with observational data. The primary focus of the existing literature has been the estimation of the local average treatment effect at the existing treatment cutoff. In contrast, we consider policy learning under the RD design. Because the treatment assignment mechanism is deterministic, learning better treatment cutoffs requires extrapolation. We develop a robust optimization approach to finding…

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Large-scale Multiple Testing of Cross-covariance Functions with Applications to Functional Network Models

交叉协方差函数的大规模多重检验及其在函数网络模型中的应用

The estimation of functional networks through functional covariance and graphical models have recently attracted increasing attention in settings with high dimensional functional data, where the number of functional variables p is comparable to, and maybe larger than, the number of subjects. However, the existing methods all depend on regularization techniques, which make it unclear how the involved tuning parameters are related to the number of false edges. In this paper,…

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Fitting an Equation to Data Impartially

对称地拟合数据中的方程关系

We consider the problem of fitting a relationship (e.g. a potential scientific law) to data involving multiple variables. Ordinary (least squares) regression is not suitable for this because the estimated relationship will differ according to which variable is chosen as being dependent, and the dependent variable is unrealistically assumed to be the only variable which has any measurement error (noise). We present a very general method for estimating a linear functional…

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Rank-transformed subsampling: inference for multiple data splitting and exchangeable p-values

秩变换子抽样:多重数据划分与可交换 p 值的推断

Many testing problems are readily amenable to randomised tests such as those employing data splitting. However despite their usefulness in principle, randomised tests have obvious drawbacks. Firstly, two analyses of the same dataset may lead to different results. Secondly, the test typically loses power because it does not fully utilise the entire sample. As a remedy to these drawbacks, we study how to combine the test statistics or p-values resulting from multiple random…

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A Principal Square Response Forward Regression Method for Dimension Reduction

主平方响应前向回归的降维方法

Dimension reduction techniques, such as Sufficient Dimension Reduction (SDR), are indispensable for analyzing high-dimensional datasets. This paper introduces a novel SDR method named Principal Square Response Forward Regression (PSRFR) for estimating the central subspace of the response variable Y, given the vector of predictor variables $\bm{X}$. We provide a computational algorithm for implementing PSRFR and establish its consistency and asymptotic properties. Monte Carlo…

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Double Machine Learning at Scale to Predict Causal Impact of Customer Actions

大规模双重机器学习:预测客户行为的因果影响

Causal Impact (CI) of customer actions are broadly used across the industry to inform both short- and long-term investment decisions of various types. In this paper, we apply the double machine learning (DML) methodology to estimate the CI values across 100s of customer actions of business interest and 100s of millions of customers. We operationalize DML through a causal ML library based on Spark with a flexible, JSON-driven model configuration approach to estimate CI at…

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Simulation-calibration testing for inference in Lasso regressions

Lasso 回归推断的模拟校准检验

We propose a test of the significance of a variable appearing on the Lasso path and use it in a procedure for selecting one of the models of the Lasso path, controlling the Family-Wise Error Rate. Our null hypothesis depends on a set A of already selected variables and states that it contains all the active variables. We focus on the regularization parameter value from which a first variable outside A is selected. As the test statistic, we use this quantity's conditional…

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Estimand-based Inference in Presence of Long-Term Survivors

存在长期存活者时基于目标量的推断

In this article, we develop nonparametric inference methods for comparing survival data across two samples, which are beneficial for clinical trials of novel cancer therapies where long-term survival is a critical outcome. These therapies, including immunotherapies or other advanced treatments, aim to establish durable effects. They often exhibit distinct survival patterns such as crossing or delayed separation and potentially leveling-off at the tails of survival curves,…

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A sparse PAC-Bayesian approach for high-dimensional quantile prediction

高维分位数预测的稀疏 PAC-Bayes 方法

Quantile regression, a robust method for estimating conditional quantiles, has advanced significantly in fields such as econometrics, statistics, and machine learning. In high-dimensional settings, where the number of covariates exceeds sample size, penalized methods like lasso have been developed to address sparsity challenges. Bayesian methods, initially connected to quantile regression via the asymmetric Laplace likelihood, have also evolved, though issues with posterior…

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Inference for linear functionals of high-dimensional longitudinal proteomics data using generalized estimating equations

高维纵向蛋白质组数据中广义估计方程线性泛函的推断

Regression analysis of correlated data, where multiple correlated responses are recorded on the same unit, is ubiquitous in many scientific areas. With the advent of new technologies, in particular high-throughput omics profiling assays, such correlated data increasingly consist of large number of variables compared with the available sample size. Motivated by recent longitudinal proteomics studies of COVID-19, we propose a novel inference procedure for linear functionals of…

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Uplift Modeling Under Limited Supervision

有限监督下的增益建模

Estimating causal effects in e-commerce tends to involve costly treatment assignments which can be impractical in large-scale settings. Leveraging machine learning to predict such treatment effects without actual intervention is a standard practice to diminish the risk. However, existing methods for treatment effect prediction tend to rely on training sets of substantial size, which are built from real experiments and are thus inherently risky to create. In this work we…

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Double Machine Learning meets Panel Data -- Promises, Pitfalls, and Potential Solutions

双重机器学习与面板数据:潜力、陷阱及可能的解决方案

Estimating causal effect using machine learning (ML) algorithms can help to relax functional form assumptions if used within appropriate frameworks. However, most of these frameworks assume settings with cross-sectional data, whereas researchers often have access to panel data, which in traditional methods helps to deal with unobserved heterogeneity between units. In this paper, we explore how we can adapt double/debiased machine learning (DML) (Chernozhukov et al., 2018)…

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Bayesian nonparametric mixtures of categorical directed graphs for heterogeneous causal inference

用于异质性因果推断的分类变量有向图贝叶斯非参数混合模型

Quantifying causal effects of exposures on outcomes, such as a treatment and a disease respectively, is a crucial issue in medical science for the administration of effective therapies. Importantly, any related causal analysis should account for all those variables, e.g. clinical features, that can act as risk factors involved in the occurrence of a disease. In addition, the selection of targeted strategies for therapy administration requires to quantify such treatment…

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Bandit Algorithms for Policy Learning: Methods, Implementation, and Welfare-performance

政策学习中的多臂老虎机算法:方法、实现与福利表现

Static supervised learning-in which experimental data serves as a training sample for the estimation of an optimal treatment assignment policy-is a commonly assumed framework of policy learning. An arguably more realistic but challenging scenario is a dynamic setting in which the planner performs experimentation and exploitation simultaneously with subjects that arrive sequentially. This paper studies bandit algorithms for learning an optimal individualised treatment…

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Adaptive Split Balancing for Optimal Random Forest

实现最优收敛率的自适应分裂平衡随机森林

In this paper, we propose a new random forest algorithm that constructs the trees using a novel adaptive split-balancing method. Rather than relying on the widely-used random feature selection, we propose a permutation-based balanced splitting criterion. The adaptive split balancing forest (ASBF), achieves minimax optimality under the Lipschitz class. Its localized version, which fits local regressions at the leaf level, attains the minimax rate under the broad Hölder class $\mathcal{H}^{q,β}$…

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Long-term Causal Inference Under Persistent Confounding via Data Combination

持续混杂下通过数据结合开展长期因果推断

We study the identification and estimation of long-term treatment effects when both experimental and observational data are available. Since the long-term outcome is observed only after a long delay, it is not measured in the experimental data, but only recorded in the observational data. However, both types of data include observations of some short-term outcomes. In this paper, we uniquely tackle the challenge of persistent unmeasured confounders, i.e., some unmeasured…

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Estimation of Optimal Dynamic Treatment Assignment Rules under Policy Constraints

政策约束下最优动态处理分配规则的估计

Many policies involve dynamics in their treatment assignments, where individuals receive sequential interventions over multiple stages. We study estimation of an optimal dynamic treatment regime that guides the optimal treatment assignment for each individual at each stage based on their history. We propose an empirical welfare maximization approach in this dynamic framework, which estimates the optimal dynamic treatment regime using data from an experimental or…

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Variable selection in the joint frailty model of recurrent and terminal events using Broken Adaptive Ridge regression

复发与终末事件联合脆弱模型中的Broken Adaptive Ridge变量选择

We introduce a novel method to simultaneously perform variable selection and estimation in the joint frailty model of recurrent and terminal events using the Broken Adaptive Ridge Regression penalty. The BAR penalty can be summarized as an iteratively reweighted squared $L_2$-penalized regression, which approximates the $L_0$-regularization method. Our method allows for the number of covariates to diverge with the sample size. Under certain regularity conditions, we prove…

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Evidence Estimation in Gaussian Graphical Models Using a Telescoping Block Decomposition of the Precision Matrix

基于精度矩阵伸缩块分解的高斯图模型证据估计

Marginal likelihood, also known as model evidence, is a fundamental quantity in Bayesian statistics. It is used for model selection using Bayes factors or for empirical Bayes tuning of prior hyper-parameters. Yet, the calculation of evidence has remained a longstanding open problem in Gaussian graphical models. Currently, the only feasible solutions that exist are for special cases such as the Wishart or G-Wishart, in moderate dimensions. We develop an approach based on a…

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Comparing Propensity Score-Based Methods in Estimating the Treatment Effects: A Simulation Study

倾向得分处理效应估计方法的模拟比较

In observational studies, the recorded treatment assignment is not purely random, but it is influenced by external factors such as patient characteristics, reimbursement policies, and existing guidelines. Therefore, the treatment effect can be estimated only after accounting for confounding factors. Propensity score (PS) methods are a family of methods that is widely used for this purpose. Although they are all based on the estimation of the a posteriori probability of…

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Estimation and inference of average treatment effects under heterogeneous additive treatment effect model

异质加性处理效应模型下平均处理效应的估计与推断

Randomized experiments are the gold standard for estimating treatment effects, yet network interference challenges the validity of traditional estimators by violating the stable unit treatment value assumption and introducing bias. While cluster randomized experiments mitigate this bias, they encounter limitations in handling network complexity and fail to distinguish between direct and indirect effects. To address these challenges, we develop a design-based asymptotic…

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State Space Model of Realized Volatility under the Existence of Dependent Market Microstructure Noise

存在相关市场微观结构噪声时的已实现波动率状态空间模型

Volatility means the degree of variation of a stock price which is important in finance. Realized Volatility (RV) is an estimator of the volatility calculated using high-frequency observed prices. RV has lately attracted considerable attention of econometrics and mathematical finance. However, it is known that high-frequency data includes observation errors called market microstructure noise (MN). Nagakura and Watanabe[2015] proposed a state space model that resolves RV into…

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An Oracle Gradient Regularized Newton Method for Quadratic Measurements Regression

二次测量回归的Oracle梯度正则化牛顿法

Recovering an unknown signal from quadratic measurements has gained popularity due to its wide range of applications, including phase retrieval, fusion frame phase retrieval, and positive operator-valued measures. In this paper, we employ a least squares approach to reconstruct the signal and establish its non-asymptotic statistical properties. Our analysis shows that the estimator perfectly recovers the true signal in the noiseless case, while the error between the…

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Model-based clustering for covariance matrices via penalized Wishart mixture models

基于惩罚Wishart混合模型的协方差矩阵聚类

Covariance matrices provide a valuable source of information about complex interactions and dependencies within the data. However, from a clustering perspective, this information has often been underutilized and overlooked. Indeed, commonly adopted distance-based approaches tend to rely primarily on mean levels to characterize and differentiate between groups. Recently, there have been promising efforts to cluster covariance matrices directly, thereby distinguishing groups…

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