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用于因果效应估计的组合式模型AI 解读

Many real-world systems can be usefully represented as sets of interacting components. Examples include computational systems, such as query processors and compilers, natural systems, such as cells and ecosystems, and social systems, such as families and organizations. However, current approaches to estimating potential outcomes and causal effects typically treat such systems as single units, represent them with a fixed set of variables, and assume a homogeneous…

未测混杂下生存结局平均处理效应的双重稳健工具变量方法AI 解读

Motivated by conflicting conclusions regarding hydrocortisone's treatment effect on ICU patients with vasopressor-dependent septic shock, we developed a novel instrumental variable (IV) estimator to assess the average treatment effect (ATE) in time-to-event data. In real-world data, IV methods are widely used for estimating causal treatment effects in the presence of unmeasured confounding, but existing approaches for time-to-event outcomes are often constrained by strong…

中介与时变剂量反应曲线的序贯核嵌入AI 解读

We propose simple nonparametric estimators for mediated and time-varying dose response curves based on kernel ridge regression. By embedding Pearl's mediation formula and Robins' g-formula with kernels, we allow treatments, mediators, and covariates to be continuous in general spaces, and also allow for nonlinear treatment-confounder feedback. Our key innovation is a reproducing kernel Hilbert space technique called sequential kernel embedding, which we use to construct…

BudgetIV：多数工具变量无效时因果效应的最优部分识别AI 解读

Instrumental variables (IVs) are widely used to estimate causal effects in the presence of unobserved confounding between exposure and outcome. An IV must affect the outcome exclusively through the exposure and be unconfounded with the outcome. We present a framework for relaxing either or both of these strong assumptions with tuneable and interpretable budget constraints. Our algorithm returns a feasible set of causal effects that can be identified exactly given relevant…

从多模态生物医学观测中学习因果表征AI 解读

Prevalent in biomedical applications (e.g., human phenotype research), multimodal datasets can provide valuable insights into the underlying physiological mechanisms. However, current machine learning (ML) models designed to analyze these datasets often lack interpretability and identifiability guarantees, which are essential for biomedical research. Recent advances in causal representation learning have shown promise in identifying interpretable latent causal variables with…

利用 LU 分解识别与估计结构向量自回归模型AI 解读

Structural vector autoregressive (SVAR) models are widely used to analyze the simultaneous relationships between multiple time-dependent data. Various statistical inference methods have been studied to overcome the identification problems of SVAR models. However, most of these methods impose strong assumptions for innovation processes such as the uncorrelation of components. In this study, we relax the assumptions for innovation processes and propose an identification method…

含未测混杂因素的广义线性模型同时推断AI 解读

Tens of thousands of simultaneous hypothesis tests are routinely performed in genomic studies to identify differentially expressed genes. However, due to unmeasured confounders, many standard statistical approaches may be substantially biased. This paper investigates the large-scale hypothesis testing problem for multivariate generalized linear models in the presence of confounding effects. Under arbitrary confounding mechanisms, we propose a unified statistical estimation…

分层获益概率：部分识别与稳健、稳定的推断AI 解读

We define the Probability of Tiered Benefit in scenarios with a binary exposure and an outcome that is either categorical with $K \geq 2$ ordered tiers or continuous partitioned by $K-1$ fixed thresholds into disjoint intervals. Similarly to other pure counterfactual queries, this parameter is not $g$-identifiable without additional assumptions. We demonstrate that strong monotonicity does not suffice for point identification when $K \geq 3$ and provide sharp bounds both…

带群组识别的高维因子模型惩罚主成分分析AI 解读

This paper investigates the intrinsic group structures within the framework of large-dimensional approximate factor models, which portrays homogeneous effects of the common factors on the individuals that fall into the same group. To this end, we propose a fusion Penalized Principal Component Analysis (PPCA) method and derive a closed-form solution for the $\ell_2$-norm optimization problem. We also show the asymptotic properties of our proposed PPCA estimates. With the PPCA…

具有选择性资格的纵向因果推断AI 解读

Dropout poses a significant challenge to causal inference in longitudinal studies with time-varying treatments. However, existing research does not simultaneously address dropout and time-varying treatments. We examine selective eligibility, an important yet overlooked source of non-ignorable dropout in such settings. This problem arises when a unit's prior treatment history influences its eligibility for subsequent treatments, a common scenario in medical and other…

面向具有空间或协变量依赖文档的图主题建模AI 解读

We address the challenge of incorporating document-level metadata into topic modeling to improve topic mixture estimation. To overcome the computational complexity and lack of theoretical guarantees in existing Bayesian methods, we extend probabilistic latent semantic indexing (pLSI), a frequentist framework for topic modeling, by incorporating document-level covariates or known similarities between documents through a graph formalism. Modeling documents as nodes and edges…

面板数据交互效应的估计AI 解读

This paper analyzes how interaction effects can be consistently estimated under economically plausible assumptions in linear panel models with a fixed $T$-dimension. We advocate for a \emph{correlated interaction term estimator} (CITE) and show that it is consistent under conditions that are not sufficient for consistency of the interaction term estimator that is most common in applied econometric work. Our paper discusses the empirical content of these conditions, shows…

经验贝叶斯估计量的超额均方误差AI 解读

Empirical Bayes estimators are based on minimizing the average risk with the hyper-parameters in the weighting function being estimated from observed data. The performance of an empirical Bayes estimator is typically evaluated by its mean squared error (MSE). However, the explicit expression for its MSE is generally unavailable for finite sample sizes. To address this issue, we define a high-order analytical criterion: the excess MSE. It quantifies the performance difference…

通过双重抽样处理缺失数据的因果分位数处理效应AI 解读

Causal weighted quantile treatment effects (WQTE) are a useful complement to standard causal contrasts that focus on the mean when interest lies at the tails of the counterfactual distribution. To-date, however, methods for estimation and inference regarding causal WQTEs have assumed complete data on all relevant factors. In most practical settings, however, data will be missing or incomplete data, particularly when the data are not collected for research purposes, as is the…

微生物组实验中复杂测量误差的建模：相对丰度与检测效应估计AI 解读

Accurate estimates of microbial species abundances are needed to advance our understanding of the role that microbiomes play in human and environmental health. However, artificially constructed microbiomes demonstrate that intuitive estimators of microbial relative abundances are biased. To address this, we propose a semiparametric method to estimate relative abundances, species detection effects, and/or cross-sample contamination in microbiome experiments. We show that…

过参数化时间序列线性模型中的良性过拟合AI 解读

The success of large-scale models in recent years has increased the importance of statistical models with numerous parameters. Several studies have analyzed over-parameterized linear models with high-dimensional data, which may not be sparse; however, existing results rely on the assumption of sample independence. In this study, we analyze a linear regression model with dependent time-series data in an over-parameterized setting. We consider an estimator using interpolation…

高维线性因子混合分类中高斯普适性的失效AI 解读

The assumption of Gaussian or Gaussian mixture data has been extensively exploited in a long series of precise performance analyses of machine learning (ML) methods, on large datasets having comparably numerous samples and features. To relax this restrictive assumption, subsequent efforts have been devoted to establish "Gaussian equivalent principles" by studying scenarios of Gaussian universality where the asymptotic performance of ML methods on non-Gaussian data remains…

面向具有网络效应的离散选择设计图卷积神经网络AI 解读

We introduce a novel model architecture that incorporates network effects into discrete choice problems, achieving higher predictive performance than standard discrete choice models while offering greater interpretability than general-purpose flexible model classes. Econometric discrete choice models aid in studying individual decision-making, where agents select the option with the highest reward from a discrete set of alternatives. Intuitively, the utility an individual…

用双重差分评估政策效应异质性驱动因素的因果框架AI 解读

Policymakers and researchers often seek to understand how a policy differentially affects a population and the pathways driving this heterogeneity. For example, when studying an excise tax on sweetened beverages, researchers might assess the roles of cross-border shopping, economic competition, and store-level price changes on beverage sales trends. However, traditional policy evaluation tools, like the difference-in-differences (DiD) approach, primarily target average…

扩散模型概率流 ODE 的极小极大最优性AI 解读

Score-based diffusion models have become a foundational paradigm for modern generative modeling, demonstrating exceptional capability in generating samples from complex high-dimensional distributions. Despite the dominant adoption of probability flow ODE-based samplers in practice due to their superior sampling efficiency and precision, rigorous statistical guarantees for these methods have remained elusive in the literature. This work develops the first end-to-end…

L-mixing 时间序列下经典谱估计量的非渐近分析AI 解读

Spectral estimation is a fundamental problem for time series analysis, which is widely applied in economics, speech analysis, seismology, and control systems. The asymptotic convergence theory for classical, non-parametric estimators, is well-understood, but the non-asymptotic theory is still rather limited. Our recent work gave the first non-asymptotic error bounds on the well-known Bartlett and Welch methods, but under restrictive assumptions. In this paper, we derive…

高维稳健回归的广义贝叶斯方法：序列相关误差与预测变量AI 解读

This paper introduces a loss-based generalized Bayesian methodology for high-dimensional robust regression with serially correlated errors and predictors. The proposed framework employs a novel scaled pseudo-Huber (SPH) loss function, which smooths the well-known Huber loss, effectively balancing quadratic ($\ell_2$) and absolute linear ($\ell_1$) loss behaviors. This flexibility enables the framework to accommodate both thin-tailed and heavy-tailed data efficiently. The…

自洽方程引导的神经网络用于删失时间事件数据AI 解读

In survival analysis, estimating the conditional survival function given predictors is often of interest. There is a growing trend in the development of deep learning methods for analyzing censored time-to-event data, especially when dealing with high-dimensional predictors that are complexly interrelated. Many existing deep learning approaches for estimating the conditional survival functions extend the Cox regression models by replacing the linear function of predictor…

利用信息性目标矩阵的高维协方差矩阵正则化AI 解读

The sample covariance matrix becomes non-invertible in high-dimensional settings, making classical multivariate statistical methods inapplicable. Various regularization techniques address this issue by imposing a structured target matrix to improve stability and invertibility. While diagonal matrices are commonly used as targets due to their simplicity, more informative target matrices can enhance performance. This paper explores the use of such targets and estimates the…