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ICH E9（R1）框架下随机试验累积发生率与处理效应的推断AI 解读

In randomized controlled trials (RCTs) that focus on time-to-event outcomes, intercurrent events can arise in two ways: as semi-competing events, which modify the hazard of the primary outcome events, or as competing events, which make the definition of the primary outcome events unclear. Although five strategies have been proposed in the ICH E9 (R1) addendum to address intercurrent events in RCTs, these strategies are not easily applicable to time-to-event outcomes when…

向量自回归中的关系图：大衰退与经济指标连接变化AI 解读

Under a high-dimensional vector autoregressive (VAR) model, we propose a way of efficiently estimating both the stationary graph structure between the nodal time series and their temporal dynamics. The framework is then used to make inferences on the change in interdependencies between several economic indicators due to the impact of the Great Recession, the financial crisis that lasted from 2007 through 2009. There are several key advantages of the proposed framework; (1)…

利用辅助变量提高时变处理效应估计效率AI 解读

Contextual sensing and delivery of digital interventions to improve health outcomes have gained significant traction in behavioral and psychiatric studies. Micro-randomized trials (MRTs) are a common experimental design for obtaining data-driven evidence on the effectiveness of digital interventions where each individual is repeatedly randomized to receive treatments over numerous time points. Throughout the study, individual characteristics and contextual factors around…

改进主研究/外部验证研究设计下回归校准的可迁移性AI 解读

In epidemiology, obtaining accurate individual exposure measurements can be costly and challenging. Thus, these measurements are often subject to error. Regression calibration with a validation study is widely employed as a study design and analysis method to correct for measurement error in the main study due to its broad applicability and simple implementation. However, relying on an external validation study to assess the measurement error process carries the risk of…

因果推断中多类处理效应的统一估计方法AI 解读

In this paper, we introduce a unified estimator to analyze various treatment effects in causal inference, including but not limited to the average treatment effect (ATE) and the quantile treatment effect (QTE). The proposed estimator is developed under the statistical functional and cumulative distribution function structure, which leads to a flexible and robust estimator and covers some frequent treatment effects. In addition, our approach also takes variable selection into…

竞争性参与者下的政策学习AI 解读

Decision makers often aim to learn a treatment assignment policy under a capacity constraint on the number of agents that they can treat. When agents can respond strategically to such policies, competition arises, complicating estimation of the optimal policy. In this paper, we study capacity-constrained treatment assignment in the presence of such interference. We consider a dynamic model where the decision maker allocates treatments at each time step and heterogeneous…

层级非线性时间序列的多重插补及其入学率应用AI 解读

International comparisons of hierarchical time series data sets based on survey data, such as annual country-level estimates of school enrollment rates, can suffer from large amounts of missing data due to differing coverage of surveys across countries and across times. A popular approach to handling missing data in these settings is through multiple imputation, which can be especially effective when there is an auxiliary variable that is strongly predictive of and has a…

Sparklen：面向高维霍克斯过程的 Python 统计学习工具包AI 解读

This paper introduces Sparklen, a statistical learning toolkit for Hawkes processes in Python, designed to bring together efficiency and ease of use. The purpose of this package is to provide the Python community with a complete suite of cutting-edge tools specifically tailored for the study of exponential Hawkes processes, with a particular focus on highdimensional framework. It includes state-of-the-art estimation tools with built-in support for incorporating…

tempdisagg：时间序列时间分解的 Python 框架AI 解读

tempdisagg is a modern, extensible, and production-ready Python framework for temporal disaggregation of time series data. It transforms low-frequency aggregates into consistent, high-frequency estimates using a wide array of econometric techniques-including Chow-Lin, Denton, Litterman, Fernandez, and uniform interpolation-as well as enhanced variants with automated estimation of key parameters such as the autocorrelation coefficient rho. The package introduces features…

利用 Google Trends 构建私人消费趋势指数AI 解读

In recent years, the use of databases that analyze trends, sentiments or news to make economic projections or create indicators has gained significant popularity, particularly with the Google Trends platform. This article explores the potential of Google search data to develop a new index that improves economic forecasts, with a particular focus on one of the key components of economic activity: private consumption (64\% of GDP in Peru). By selecting and estimating…

固定时期数线性因子模型中处理效应的识别与估计AI 解读

This paper provides a new approach for identifying and estimating the Average Treatment Effect on the Treated under a linear factor model that allows for multiple time-varying unobservables. Unlike the majority of the literature on treatment effects in linear factor models, our approach does not require the number of pre-treatment periods to go to infinity to obtain a valid estimator. Our identification approach employs a certain nonlinear transformations of the time…

动态断点回归：事件研究方法AI 解读

I propose a novel argument to identify economically interpretable intertemporal treatment effects in dynamic regression discontinuity designs (RDDs). Specifically, I develop a dynamic potential outcomes model and reformulate two assumptions from the difference-in-differences literature, no anticipation and common trends, to attain point identification of cutoff-specific impulse responses. The estimand of each target parameter can be expressed as the sum of two static RDD…

利用伪观测进行协变量调整的限制平均生存时间贝叶斯分析AI 解读

The difference in restricted mean survival time (RMST) is a clinically meaningful measure to quantify treatment effect in randomized controlled trials, especially when the proportional hazards assumption does not hold. Several frequentist methods exist to estimate RMST adjusted for covariates based on modeling and integrating the survival function. A more natural approach may be a regression model on RMST using pseudo-observations, which allows for a direct estimation…

多层网络回归中的特征向量中心性与社区结构AI 解读

In the analysis of complex networks, centrality measures and community structures play pivotal roles. For multilayer networks, a critical challenge lies in effectively integrating information across diverse layers while accounting for the dependence structures both within and between layers. We propose an innovative two-stage regression model for multilayer networks, combining eigenvector centrality and network community structure within fourth-order tensor-like multilayer…

将元分析整合到特定研究中以估计条件平均处理效应：InMASSAI 解读

Randomized controlled trials are the standard method for estimating causal effects, ensuring sufficient statistical power and confidence through adequate sample sizes. However, achieving such sample sizes is often challenging. This study proposes a novel method for estimating the average treatment effect (ATE) in a target population by integrating and reconstructing information from previous trials using only summary statistics of outcomes and covariates through…

临床试验中利用外部对照：目标量、估计与假设AI 解读

It is increasingly common to augment randomized controlled trial with external controls from observational data, to evaluate the treatment effect of an intervention. Traditional approaches to treatment effect estimation involve ambiguous estimands and unrealistic or strong assumptions, such as mean exchangeability. We introduce a double-indexed notation for potential outcomes to define causal estimands transparently and clarify distinct sources of implicit bias. We show that…

未观测混杂下多处理因果推断的copula敏感性分析AI 解读

Recent work has focused on the potential and pitfalls of causal identification in observational studies with multiple simultaneous treatments. Building on previous work, we show that even if the conditional distribution of unmeasured confounders given treatments were known exactly, the causal effects would not in general be identifiable, although they may be partially identified. Given these results, we propose a sensitivity analysis method for characterizing the effects of…

具有多重符号与排序限制的大型结构VARAI 解读

Large VARs are increasingly used in structural analysis as a unified framework to study the impacts of multiple structural shocks simultaneously. However, the concurrent identification of multiple shocks using sign and ranking restrictions poses significant practical challenges to the point where existing algorithms cannot be used with such large VARs. To address this, we introduce a new numerically efficient algorithm that facilitates the estimation of impulse responses and…

重审希尔伯特空间学习中的一般源条件AI 解读

In Learning Theory, the smoothness assumption on the target function (known as source condition) is a key factor in establishing theoretical convergence rates for an estimator. The existing general form of the source condition, as discussed in learning theory literature, has traditionally been restricted to a class of functions that can be expressed as a product of an operator monotone function and a Lipschitz continuous function. In this note, we remove these restrictions…

深度模式及其在动物追踪中的应用AI 解读

We establish a definition of ordinal patterns for multivariate data sets based on the concept of Tukey's halfspace depth. Given the definition of these \emph{depth patterns}, we are interested in the probabilities of observing specific patterns in time series. For this, we consider the relative frequency of depth patterns as natural estimators for their occurrence probabilities. Depending on the choice of reference distribution and the relation between reference and data…

具有样本外保证的函数型结构方程模型AI 解读

Statistical learning methods typically assume that the training and test data originate from the same distribution, enabling effective risk minimization. However, real-world applications frequently involve distributional shifts, leading to poor model generalization. To address this, recent advances in causal inference and robust learning have introduced strategies such as invariant causal prediction and anchor regression. While these approaches have been explored for…

非参数面板模型中平均处理效应的识别AI 解读

This paper studies identification of average treatment effects in a panel data setting. It introduces a novel nonparametric factor model and proves identification of average treatment effects. The identification proof is based on the introduction of a consistent estimator. Underlying the proof is a result that there is a consistent estimator for the expected outcome in the absence of the treatment for each unit and time period; this result can be applied more broadly, for…

联邦因果推断：超越元分析的多研究平均处理效应估计AI 解读

We study Federated Causal Inference, an approach to estimate treatment effects from decentralized data across centers. We compare three classes of Average Treatment Effect (ATE) estimators derived from the Plug-in G-Formula, ranging from simple meta-analysis to one-shot and multi-shot federated learning, the latter leveraging the full data to learn the outcome model (albeit requiring more communication). Focusing on Randomized Controlled Trials (RCTs), we derive the…

基于区块最大值方法的估计量自助法AI 解读

The block maxima method is a standard approach for analyzing the extremal behavior of a potentially multivariate time series. It has recently been found that the classical approach based on disjoint block maxima may be universally improved by considering sliding block maxima instead. However, the asymptotic variance formula for estimators based on sliding block maxima involves an integral over the covariance of a certain family of multivariate extreme value distributions,…