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揭示观测研究中的偏差机制AI 解读

Observational studies are a key resource for causal inference but are often affected by systematic biases. Prior work has focused mainly on detecting these biases, via sensitivity analyses and comparisons with randomized controlled trials, or mitigating them through debiasing techniques. However, there remains a lack of methodology for uncovering the underlying mechanisms driving these biases, e.g., whether due to hidden confounding or selection of participants. In this…

时变安慰剂效应确证性临床试验中的半参数加权样条回归AI 解读

In confirmatory Phase 3 clinical trials with recruitment over the years, the underlying placebo effect may follow an unknown temporal trend. Taking a clinical trial on Hidradenitis Suppurativa (HS) as an example, fluctuations or variabilities are common in HS-related endpoints, mainly due to the natural disease characteristics, variations of evaluation from different physicians, and standard of care evolvement. The adjustment of time-varying placebo effects receives some…

带协变量的多臂老虎机核 ε-贪心策略AI 解读

We consider the $ε$-greedy strategy for the multi-arm bandit with covariates (MABC) problem, where the mean reward functions are assumed to lie in a reproducing kernel Hilbert space (RKHS). We propose to estimate the unknown mean reward functions using an online weighted kernel ridge regression estimator, and show the resultant estimator to be consistent under appropriate decay rates of the exploration probability sequence, $\{ε_t\}_t$, and regularization parameter, $\{λ_t\}_t$…

投影寻踪密度比估计AI 解读

Density ratio estimation (DRE) is a paramount task in machine learning, for its broad applications across multiple domains, such as covariate shift adaptation, causal inference, independence tests and beyond. Parametric methods for estimating the density ratio possibly lead to biased results if models are misspecified, while conventional non-parametric methods suffer from the curse of dimensionality when the dimension of data is large. To address these challenges, in this…

因子化尾部波动模型：扩展高维厚尾数据的超阈值方法AI 解读

Ecess-over-Threshold method is a crucial technique in extreme value analysis, which approximately models larger observations over a threshold using a Generalized Pareto Distribution. This paper presents a comprehensive framework for analyzing tail risk in high-dimensional data by introducing the Factorized Tail Volatility Model (FTVM) and integrating it with central quantile models through the EoT method. This integrated framework is termed the FTVM-EoT method. In this…

最节能路径问题的载重渐近分析与动态速度优化AI 解读

We study the effect of using high-resolution elevation data on the selection of the most fuel-efficient(greenest) path for different trucks in various urban environments.We adapt a variant of the Comprehensive Modal Emission Model(CMEM) to show that the optimal speed and the greenest path are slope dependent (dynamic).When there are no elevation changes in a road network, the most fuel-efficient path is the shortest path with a constant (static) optimal speed…

个体参与者数据元分析中处理效应的学生化置换检验AI 解读

Meta-analysis is a well-established tool used to combine data from several independent studies, each of which usually compares the effect of an experimental treatment with a control group. While meta-analyses are often performed using aggregated study summaries, they may also be conducted using individual participant data (IPD). Classical meta-analysis models may be generalized to handle continuous IPD by formulating them within a linear mixed model framework. IPD…

嵌套非参数工具变量回归AI 解读

Several causal parameters in short panel data models are functionals of a nested nonparametric instrumental variable regression (nested NPIV). Recent examples include mediated, time varying, and long term treatment effects identified using proxy variables. In econometrics, examples arise in triangular simultaneous equations and hedonic price systems. However, it appears that explicit mean square convergence rates for nested NPIV are unknown, preventing inference on some of…

比例风险模型中的倾向加权加回归调整不具一般双重稳健性AI 解读

Recently, it has become common for applied works to combine commonly used survival analysis modeling methods, such as the multivariable Cox model and propensity score weighting, with the intention of forming a doubly robust estimator of an exposure effect hazard ratio that is unbiased in large samples when either the Cox model or the propensity score model is correctly specified. This combination does not, in general, produce a doubly robust estimator, even after regression…

用于因果效应部分识别的数据融合AI 解读

Data fusion techniques integrate information from heterogeneous data sources to improve learning, generalization, and decision making across data sciences. In causal inference, these methods leverage rich observational data to improve causal effect estimation, while maintaining the trustworthiness of randomized controlled trials. Existing approaches often relax the strong no unobserved confounding assumption by instead assuming exchangeability of counterfactual outcomes…

通过纳入协变量的最优传输收紧因果效应界AI 解读

Causal estimands can vary significantly depending on the relationship between outcomes in treatment and control groups, potentially leading to wide partial identification (PI) intervals that impede decision making. Incorporating covariates can substantially tighten these bounds, but requires determining the range of PI over probability models consistent with the joint distributions of observed covariates and outcomes in treatment and control groups. This problem is known to…

用于总价值最大化的经验贝叶斯选择AI 解读

We study the problem of selecting the best $m$ units from a set of $n$ as $m / n \to α\in (0, 1)$, where noisy, heteroskedastic measurements of the units' true values are available and the decision-maker wishes to maximize the aggregate true value of the units selected. Given a parametric prior distribution, the empirical Bayes decision rule incurs $O_p(n^{-1})$ regret relative to the Bayesian oracle that knows the true prior. More generally, if the error in the estimated…

基于正态混合准极大似然的双重自回归模型稳健估计AI 解读

This paper investigates the estimation of the double autoregressive (DAR) model in the presence of skewed and heavy-tailed innovations. We propose a novel Normal Mixture Quasi-Maximum Likelihood Estimation (NM-QMLE) method to address the limitations of conventional quasi-maximum likelihood estimation (QMLE) under non-Gaussian conditions. By incorporating a normal mixture distribution into the quasi-likelihood framework, NM-QMLE effectively captures both heavy-tailed behavior…

一般一阶方法的逐元素动力学与普适性AI 解读

General first order methods (GFOMs), including various gradient descent and AMP algorithms, constitute a broad class of iterative algorithms in modern statistical learning problems. Some GFOMs also serve as constructive proof devices, iteratively characterizing the empirical distributions of statistical estimators in the large system limits for any fixed number of iterations. This paper develops a non-asymptotic, entrywise characterization for a general class of GFOMs. Our…

金融尾部风险预测评价：等预测能力检验AI 解读

This paper provides comprehensive simulation results on the finite sample properties of the Diebold-Mariano (DM) test by Diebold and Mariano (1995) and the model confidence set (MCS) testing procedure by Hansen et al. (2011) applied to the asymmetric loss functions specific to financial tail risk forecasts, such as Value-at-Risk (VaR) and Expected Shortfall (ES). We focus on statistical loss functions that are strictly consistent in the sense of Gneiting (2011a). We find…

JANET：时间序列联合自适应预测区域估计AI 解读

Conformal prediction provides machine learning models with prediction sets that offer theoretical guarantees, but the underlying assumption of exchangeability limits its applicability to time series data. Furthermore, existing approaches struggle to handle multi-step ahead prediction tasks, where uncertainty estimates across multiple future time points are crucial. We propose JANET (Joint Adaptive predictioN-region Estimation for Time-series), a novel framework for…

通过协变量调整提高复发事件曲线下面积估计精度AI 解读

The area under the curve (AUC) of the mean cumulative function (MCF) has recently been introduced as a novel estimand for evaluating treatment effects in recurrent event settings, offering an alternative to the commonly used Lin-Wei-Yang-Ying (LWYY) model. The AUC of the MCF provides a clinically interpretable summary measure that captures the overall burden of disease progression, regardless of whether the proportionality assumption holds. To improve the precision of the…

广义因果自助法设计的整数规划AI 解读

In experimental causal inference, we distinguish between two sources of uncertainty: design uncertainty, due to the treatment assignment mechanism, and sampling uncertainty, when the sample is drawn from a super-population. This distinction matters in settings with small fixed samples and heterogeneous treatment effects, as in geographical experiments. The standard bootstrap procedure most often used by practitioners primarily estimates sampling uncertainty, and the causal…

网络引导惩罚回归及其在蛋白质组学数据中的应用AI 解读

Network theory has proven invaluable in unraveling complex protein interactions. Previous studies have employed statistical methods rooted in network theory, including the Gaussian graphical model, to infer networks among proteins, identifying hub proteins based on key structural properties of networks such as degree centrality. However, there has been limited research examining a prognostic role of hub proteins on outcomes, while adjusting for clinical covariates in the…

基于简约性原则的分布外泛化理论AI 解读

Modern foundation models exhibit remarkable out-of-distribution (OOD) generalization, solving tasks far beyond the support of their training data. However, the theoretical principles underpinning this phenomenon remain elusive. This paper investigates this problem by examining the compositional generalization abilities of diffusion models in image generation. Our analysis reveals that while neural network architectures are expressive enough to represent a wide range of…

利用实验纠正观察性研究中的选择偏差AI 解读

Researchers increasingly have access to two types of data: (i) large observational datasets where treatment (e.g., class size) is not randomized but several primary outcomes (e.g., graduation rates) and secondary outcomes (e.g., test scores) are observed and (ii) experimental data in which treatment is randomized but only secondary outcomes are observed. We develop a new method to estimate treatment effects on primary outcomes in such settings. We use the difference between…

非平稳宏观数据反事实分析的合成经济周期方法AI 解读

This paper investigates the use of synthetic control methods for causal inference in macroeconomic settings when dealing with possibly nonstationary data. While the synthetic control approach has gained popularity for estimating counterfactual outcomes, we caution researchers against assuming a common nonstationary trend factor across units for macroeconomic outcomes, as doing so may result in misleading causal estimation-a pitfall we refer to as the spurious synthetic…

具有分布目标的最优政策学习中的公平性正则化AI 解读

A decision maker typically (i) incorporates training data to learn about the relative effectiveness of treatments, and (ii) chooses an implementation mechanism that implies an ``optimal'' predicted outcome distribution according to some target functional. Nevertheless, a fairness-aware decision maker may not be satisfied achieving said optimality at the cost of being ``unfair" against a subgroup of the population, in the sense that the outcome distribution in that subgroup…

高维有界响应的 Horseshoe 先验贝叶斯 Beta 回归AI 解读

Bounded continuous responses -- such as proportions -- arise frequently in diverse scientific fields including climatology, biostatistics, and finance. Beta regression is a widely adopted framework for modeling such data, due to the flexibility of the Beta distribution over the unit interval. While Bayesian extensions of Beta regression have shown promise, existing methods are limited to low-dimensional settings and lack theoretical guarantees. In this work, we propose a…