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Stochastic Boundaries in Spatial General Equilibrium: A Diffusion-Based Approach to Causal Inference with Spillover Effects

空间一般均衡中的随机边界:基于扩散的溢出效应因果推断

This paper introduces a novel framework for causal inference in spatial economics that explicitly models the stochastic transition from partial to general equilibrium effects. We develop a Denoising Diffusion Probabilistic Model (DDPM) integrated with boundary detection methods from stochastic process theory to identify when and how treatment effects propagate beyond local markets. Our approach treats the evolution of spatial spillovers as a Lévy process with jump-diffusion…

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Latent confounding in high-dimensional nonlinear models

高维非线性模型中的潜在混杂

We consider the the problem of identifying causal effects given a high-dimensional treatment vector in the presence of low-dimensional latent confounders. We assume a parametric structural causal model in which the outcome is permitted to depend on a sparse linear combination of the treatment vector and confounders nonlinearly. We consider a generalisation of the LAVA estimator of Chernozhukov et al. [2017] for estimating the treatment effects and show that under the…

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Propensity score weighting across counterfactual worlds: longitudinal effects under positivity violations

跨反事实世界的倾向得分加权:正值性违背下的纵向效应

When examining a contrast between two interventions, longitudinal causal inference studies frequently encounter positivity violations when one or both regimes are impossible to observe for some subjects. Existing weighting methods either assume positivity holds or produce effects that conflate interventions' impacts on ultimate outcomes with their effects on intermediate treatments and covariates. We propose a novel class of estimands -- cumulative cross-world weighted…

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Estimation and Inference in High-Dimensional Panel Data Models with Interactive Fixed Effects

含交互固定效应的高维面板数据模型:估计与推断

We develop new econometric methods for estimation and inference in high-dimensional panel data models with interactive fixed effects. Our approach can be regarded as a non-trivial extension of the very popular common correlated effects (CCE) approach. Roughly speaking, we proceed as follows: We first construct a projection device to eliminate the unobserved factors from the model by applying a dimensionality reduction transform to the matrix of cross-sectionally averaged…

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Consistency of an Intercept-Shifted Synthetic-Control Estimator under Weighted Parallel Trends

加权平行趋势下截距平移合成控制估计量的一致性

The average treatment effect on the treated (ATT) in a staggered-adoption panel is estimated using an intercept-augmented synthetic-control (SCM) estimator. A weighted parallel trends plus an intercept shift, together with mild regularity on the weight vectors (non-degenerate dispersion) and expanding pre-treatment length, are sufficient for consistency allowing for heavy-tailed shocks. These conditions can be more interpretable than the autoregressive or low-rank factor…

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Covariate adjustment for linear models in estimating treatment effects in randomised clinical trials. Some useful theory to guide simulation

随机临床试验处理效应估计中的线性模型协变量调整:指导模拟的理论

Building on key papers that were published in special issues of Biometrics in 1957 and 1982 we propose and develop a three-aspect system for evaluating the effect of fitting covariates in the analysis of designed experiments, in particular randomised clinical trials. The three aspects are: first the effect on residual mean square error, second the effect on the variance inflation factor (VIF) and third the effect on second order precision. We concentrate, in particular, on…

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Functional Factor Regression with an Application to Electricity Price Curve Modeling

函数型因子回归及其在电价曲线建模中的应用

We propose a function-on-function linear regression model for time-dependent curve data that is consistently estimated by imposing factor structures on the regressors. An integral operator based on cross-covariances identifies two components for each functional regressor: a predictive low-dimensional component, along with associated factors that are guaranteed to be correlated with the dependent variable, and an infinite-dimensional component that has no predictive power. In…

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DFW: A Novel Weighting Scheme for Covariate Balancing and Treatment Effect Estimation

DFW:用于协变量平衡与处理效应估计的新加权方案

Estimating causal effects from observational data is challenging due to selection bias, which leads to imbalanced covariate distributions across treatment groups. Propensity score-based weighting methods are widely used to address this issue by reweighting samples to simulate a randomized controlled trial (RCT). However, the effectiveness of these methods heavily depends on the observed data and the accuracy of the propensity score estimator. For example, inverse propensity…

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Sparse Asymptotic PCA: Identifying Sparse Latent Factors Across Time Horizon in High-Dimensional Time Series

稀疏渐近主成分分析:识别高维时间序列中跨时间的稀疏潜在因子

This paper introduces a novel sparse latent factor modeling framework using sparse asymptotic Principal Component Analysis (APCA) to analyze the co-movements of high-dimensional panel data over time. Unlike existing methods based on sparse PCA, which assume sparsity in the loading matrices, our approach posits sparsity in the factor processes while allowing non-sparse loadings. This is motivated by the fact that financial returns typically exhibit universal and non-sparse…

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Graph Estimation Based on Neighborhood Selection for Matrix-variate Data

基于邻域选择的矩阵变量数据图估计

Undirected graphical models are powerful tools for uncovering complex relationships among high-dimensional variables. This paper aims to fully recover the structure of an undirected graphical model when the data naturally take matrix form, such as temporal multivariate data. As conventional vector-variate analyses have clear limitations in handling such matrix-structured data, several approaches have been proposed, mostly relying on the likelihood of the Gaussian…

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Weak Identification in Peer Effects Estimation

同伴效应估计中的弱识别

It is commonly accepted that some phenomena are social: for example, individuals' smoking habits often correlate with those of their peers. Such correlations can have a variety of explanations, such as direct contagion or shared socioeconomic circumstances. The network linear-in-means model is a workhorse statistical model which incorporates these peer effects by including average neighborhood characteristics as regressors. Although the model's parameters are identifiable…

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Producing treatment hierarchies in network meta-analysis using probabilistic models and treatment-choice criteria

利用概率模型与治疗选择准则构建网络荟萃分析的治疗层级

A key output of network meta-analysis (NMA) is the relative ranking of treatments; nevertheless, it has attracted substantial criticism. Existing ranking methods often lack clear interpretability and fail to adequately account for uncertainty, over-emphasizing small differences in treatment effects. We propose a novel framework to estimate treatment hierarchies in NMA using a probabilistic model, focusing on a clinically relevant treatment-choice criterion (TCC). Initially,…

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High-Dimensional Matrix-Variate Diffusion Index Models for Time Series Forecasting

用于时间序列预测的高维矩阵扩散指数模型

This paper proposes a novel diffusion-index model for forecasting when predictors are high-dimensional matrix-valued time series. We apply an $α$-PCA method to extract low-dimensional matrix factors and build a bilinear regression linking future outcomes to these factors, estimated via iterative least squares. To handle weak factor structures, we introduce a supervised screening step to select informative rows and columns. Theoretical properties, including consistency and…

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Robust estimation of causal dose-response relationship using exposure data with dose as an instrumental variable

以剂量为工具变量、利用暴露数据稳健估计因果剂量响应关系

An accurate estimation of the dose-response relationship is important to determine the optimal dose. For this purpose, a dose finding trial in which subjects are randomized to a few fixed dose levels is the most commonly used design. Often, the estimation uses response data only, although drug exposure data are often obtained during the trial. The use of exposure data to improve this estimation is difficult, as exposure-response relationships are typically subject to…

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The benefit of dose-exposure-response modeling in the estimation of dose-response relationship and dose optimization: some theoretical and simulation evidence

剂量—暴露—响应建模对剂量响应估计与优化的收益

In randomized dose-finding trials, although drug exposure data form a part of key information for dose selection, the evaluation of the dose-response (DR) relationship often mainly uses DR data. We examine the benefit of dose-exposure-response (DER) modeling by sequentially modeling the dose-exposure (DE) and exposure-response (ER) relationships in parameter estimation and prediction, compared with direct DR modeling without PK data. We consider ER modeling approaches with…

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The Regression Discontinuity Design in Medical Science

医学研究中的回归不连续设计

This article provides an introduction to the Regression Discontinuity (RD) design, and its application to empirical research in the medical sciences. While the main focus of this article is on causal interpretation, key concepts of estimation and inference are also briefly mentioned. A running medical empirical example is provided.

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A New Perspective on High Dimensional Confidence Intervals

高维置信区间的新视角

Classically, confidence intervals are required to have consistent coverage across all values of the parameter. However, this will inevitably break down if the underlying estimation procedure is biased. For this reason, many efforts have focused on debiased versions of the lasso for interval construction. In the process of debiasing, however, the connection to the original estimates are often obscured. In this work, we offer a different perspective focused on average coverage…

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Bounds on causal effects in $2^{K}$ factorial experiments with non-compliance

存在不依从的2^K析因实验中因果效应的界限

Factorial experiments are ubiquitous in the social and biomedical sciences, but when units fail to comply with each assigned factors, identification and estimation of the average treatment effects become impossible without strong assumptions. Leveraging an instrumental variables approach, previous studies have shown how to identify and estimate the causal effect of treatment uptake among respondents who comply with treatment. A major caveat is that these identification…

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Nonparametric data segmentation in multivariate time series via joint characteristic functions

基于联合特征函数的多元时间序列非参数分段

Modern time series data often exhibit complex dependence and structural changes which are not easily characterised by shifts in the mean or model parameters. We propose a nonparametric data segmentation methodology for multivariate time series termed NP-MOJO. By considering joint characteristic functions between the time series and its lagged values, NP-MOJO is able to detect change points in the marginal distribution, but also those in possibly non-linear serial dependence,…

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Estimation and variable selection in high dimension in a causal joint model of survival times and longitudinal outcomes with random effects

带随机效应的生存时间与纵向结果因果联合模型:高维估计与变量选择

We consider a joint survival and mixed-effects model to explain the survival time from longitudinal data and high-dimensional covariates in a population. The longitudinal data is modeled using a non linear mixed-effects model to account for the inter-individual variability in the population. The corresponding regression function serves as a link function incorporated into the survival model. In that way, the longitudinal data is related to the survival time. We consider a…

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Identification and multiply robust estimation of causal effects via instrumental variables from an auxiliary population

利用辅助总体工具变量识别因果效应与多重稳健估计

Estimating causal effects in a target population with unmeasured confounders is challenging, especially when instrumental variables (IVs) are unavailable. However, IVs from auxiliary populations with similar problems can help infer causal effects in the target population. While the homogeneous conditional average treatment effect assumption has been widely used for effect transportability, it has not been explored in IV-based data fusion. We include it as a basic approach,…

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Estimation and variable selection in high dimension in nonlinear mixed-effects models

高维非线性混合效应模型中的估计与变量选择

We consider nonlinear mixed effects models including high-dimensional covariates to model individual parameters variability. The objective is to identify relevant covariates among a large set under sparsity assumption and to estimate model parameters. To face the high dimensional setting we consider a regularized estimator namely the maximum likelihood estimator penalized with the l1-penalty. We rely on the use of the eBIC model choice criteria to select an optimal reduced…

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Peer Effect Estimation in the Presence of Simultaneous Feedback and Unobserved Confounders

同时反馈与未观测混杂下的同伴效应估计

Estimating peer causal effects within complex real-world networks such as social networks is challenging, primarily due to simultaneous feedback between peers and unobserved confounders. Existing methods either address unobserved confounders while ignoring the simultaneous feedback, or account for feedback but under restrictive linear assumptions, thus failing to obtain accurate peer effect estimation. In this paper, we propose DIG2RSI, a novel Deep learning framework which…

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Bayesian Sensitivity Analyses for Policy Evaluation with Difference-in-Differences under Violations of Parallel Trends

平行趋势违背下双重差分政策评估的贝叶斯敏感性分析

Violations of the parallel trends assumption pose significant challenges for causal inference in difference-in-differences (DiD) studies, especially in policy evaluations where pre-treatment dynamics and external shocks may bias estimates. In this work, we propose a Bayesian DiD framework to allow us to estimate the effect of policies when parallel trends is violated. To address potential deviations from the parallel trends assumption, we introduce a formal sensitivity…

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