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Two-Way Mean Group Estimators for Heterogeneous Panel Models with Fixed T

固定时间维度下异质性面板模型的双向均值组估计

We consider a correlated random coefficient panel data model with two-way fixed effects and interactive fixed effects in a fixed T framework. We propose a two-way mean group (TW-MG) estimator for the expected value of the slope coefficient and propose a leave-one-out jackknife method for valid inference. We also consider a pooled estimator and provide a Hausman-type test for poolability. Simulations demonstrate the excellent performance of our estimators and inference…

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Temporal Wasserstein Imputation: A Versatile Method for Time Series Imputation

时间 Wasserstein 插补:一种灵活的时间序列缺失值方法

Missing data can significantly hamper standard time series analysis, yet they occur frequently in applications. In this paper, we introduce temporal Wasserstein imputation, a novel method for imputing missing data in time series. Unlike most existing techniques, our approach is fully nonparametric, circumventing the need for model specification prior to imputation, making it suitable for empirical applications even with nonlinear dynamics. Its principled algorithmic…

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Causal Identification for Complex Functional Longitudinal Studies

复杂函数型纵向研究的因果识别

Real-time monitoring in modern medical research introduces functional longitudinal data, characterized by continuous-time measurements of outcomes, treatments, and confounders. This complexity leads to uncountably infinite treatment-confounder feedbacks, which traditional causal inference methodologies cannot handle. Inspired by the coarsened data framework, we adopt stochastic process theory, measure theory, and net convergence to propose a nonparametric causal…

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Incremental Causal Effect for Time to Treatment Initialization

治疗启动时间的增量因果效应

We consider time to treatment initialization. This can commonly occur in preventive medicine, such as disease screening and vaccination; it can also occur with non-fatal health conditions such as HIV infection without the onset of AIDS; or in tech industry where items wait to be reviewed manually as abusive or not, etc. While traditional causal inference focused on `when to treat' and its effects, including their possible dependence on subject characteristics, we consider…

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Inference under Staggered Adoption: Case Study of the Affordable Care Act

交错实施下的推断:以《平价医疗法案》为例

Panel data consists of a collection of $N$ units that are observed over $T$ units of time. A policy or treatment is subject to staggered adoption if different units take on treatment at different times and remains treated (or never at all). Assessing the effectiveness of such a policy requires estimating the treatment effect, corresponding to the difference between outcomes for treated versus untreated units. We develop inference procedures that build upon a computationally…

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Regression adjustment in covariate-adaptive randomized experiments with missing covariates

协变量缺失时协变量自适应随机试验的回归调整

Covariate-adaptive randomization is widely used in clinical trials to balance prognostic factors, and regression adjustments are often adopted to further enhance the estimation and inference efficiency. In practice, the covariates may contain missing values. Various methods have been proposed to handle the covariate missing problem under simple randomization. However, the statistical properties of the resulting average treatment effect estimators under stratified…

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Consistency assessment and regional sample size calculation for MRCTs under random effects model

随机效应模型下多区域临床试验的一致性评估与样本量计算

Multi-regional clinical trials (MRCTs) have become common practice for drug development and global registration. Once overall significance is established, demonstrating regional consistency is critical for local health authorities. Methods for evaluating such consistency and calculating regional sample sizes have been proposed based on the fixed effects model using various criteria. To better account for the heterogeneity of treatment effects across regions, the random…

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M-learner:A Flexible And Powerful Framework To Study Heterogeneous Treatment Effect In Mediation Model

M-learner:中介模型中异质处理效应的学习框架

We propose a novel method, termed the M-learner, for estimating heterogeneous indirect and total treatment effects and identifying relevant subgroups within a mediation framework. The procedure comprises four key steps. First, we compute individual-level conditional average indirect/total treatment effect Second, we construct a distance matrix based on pairwise differences. Third, we apply tSNE to project this matrix into a low-dimensional Euclidean space, followed by…

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Inference in Cluster Randomized Trials with Matched Pairs

配对簇随机试验中的推断

This paper studies inference in cluster randomized trials where treatment status is determined according to a "matched pairs" design. Here, by a cluster randomized experiment, we mean one in which treatment is assigned at the level of the cluster; by a "matched pairs" design, we mean that a sample of clusters is paired according to baseline, cluster-level covariates and, within each pair, one cluster is selected at random for treatment. We study the large-sample behavior of…

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Approximate Sparsity Class and Minimax Estimation

近似稀疏函数类与极小极大估计

Motivated by the orthogonal series density estimation in $L^2([0,1],μ)$, in this project we consider a new class of functions that we call the approximate sparsity class. This new class is characterized by the rate of decay of the individual Fourier coefficients for a given orthonormal basis. We establish the $L^2([0,1],μ)$ metric entropy of such class, with which we show the minimax rate of convergence. For the density subset in this class, we propose an adaptive density…

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High-dimensional Longitudinal Inference via a De-sparsified Dantzig-Selector

高维纵向数据下基于去稀疏化 Dantzig 选择器的统计推断

In this paper, we consider statistical inference with generalized linear models in high dimensions under a longitudinal clustered data framework. Specifically, we propose a de-sparsified version of an initial Dantzig-type regularized estimator in regression settings and provide theoretical justification for both linear and generalized linear models. We present extensive numerical simulations demonstrating the effectiveness of our method for continuous and binary data. For…

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Position: Causal Machine Learning Requires Rigorous Synthetic Experiments for Broader Adoption

观点:因果机器学习的广泛应用需要严格的合成实验

Causal machine learning has the potential to revolutionize decision-making by combining the predictive power of machine learning algorithms with the theory of causal inference. However, these methods remain underutilized by the broader machine learning community, in part because current empirical evaluations do not permit assessment of their reliability and robustness, undermining their practical utility. Specifically, one of the principal criticisms made by the community is…

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Sensitivity Analysis to Unobserved Confounding with Copula-based Normalizing Flows

基于 Copula 标准化流的未观测混杂敏感性分析

We propose a novel method for sensitivity analysis to unobserved confounding in causal inference. The method builds on a copula-based causal graphical normalizing flow that we term $ρ$-GNF, where $ρ\in [-1,+1]$ is the sensitivity parameter. The parameter represents the non-causal association between exposure and outcome due to unobserved confounding, which is modeled as a Gaussian copula. In other words, the $ρ$-GNF enables scholars to estimate the average causal effect…

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Nonparametric Causal Survival Analysis with Clustered Interference

聚类干扰下的非参数因果生存分析

Inferring treatment effects on a survival time outcome based on data from an observational study is challenging due to the presence of censoring and possible confounding. An additional challenge occurs when a unit's treatment affects the outcome of other units, i.e., there is interference. In some settings, units may be grouped into clusters such that it is reasonable to assume interference only occurs within clusters, i.e., there is clustered interference. In this paper,…

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A Heterogeneous Spatiotemporal GARCH Model: A Predictive Framework for Volatility in Financial Networks

异质时空 GARCH:金融网络波动率预测框架

We introduce a heterogeneous spatiotemporal GARCH model for geostatistical data or processes on networks, e.g., for modelling and predicting financial return volatility across firms in a latent spatial framework. The model combines classical GARCH(p, q) dynamics with spatially correlated innovations and spatially varying parameters, estimated using local likelihood methods. Spatial dependence is introduced through a geostatistical covariance structure on the innovation…

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Doubly robust pointwise confidence intervals for a monotonic continuous treatment effect curve

单调连续处理效应曲线的双重稳健逐点置信区间

We study nonparametric inference for the causal dose-response (or treatment effect) curve when the treatment variable is continuous rather than binary or discrete. We do this by developing doubly robust confidence intervals for the continuous treatment effect curve (at a fixed point) under the assumption that it is monotonic, based on inverting a likelihood ratio-type test. Monotonicity of the treatment effect curve is often a very natural assumption, and this assumption…

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A Meta-Learning Method for Estimation of Causal Excursion Effects to Assess Time-Varying Moderation

评估时变调节作用的因果偏离效应元学习方法

Advances in wearable technologies and health interventions delivered by smartphones have greatly increased the accessibility of mobile health (mHealth) interventions. Micro-randomized trials (MRTs) are designed to assess the effectiveness of the mHealth intervention and introduce a novel class of causal estimands called "causal excursion effects." These estimands enable the evaluation of how intervention effects change over time and are influenced by individual…

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A Review and Classification of Model Uncertainty

模型不确定性的综述与分类

Model uncertainty is a crucial issue in statistics, econometrics and machine learning, yet its definition remains ambiguous and is subject to various interpretations in the literature. So far, there has not been a universally accepted definition of model uncertainty. We review different understandings of model uncertainty and categorize them into three distinct types: uncertainty about the true model, model selection uncertainty, and model selection instability. We further…

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Structural Periodic Vector Autoregressions

结构周期向量自回归

While seasonality inherent to raw macroeconomic data is commonly removed by seasonal adjustment techniques before it is used for structural inference, this may distort valuable information in the data. As an alternative method to commonly used structural vector autoregressions (SVARs) for seasonally adjusted data, we propose to model potential periodicity in seasonally unadjusted (raw) data directly by structural periodic vector autoregressions (SPVARs). This approach does…

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Nonparametric Estimation of Local Treatment Effects with Continuous Instruments

连续工具变量下局部处理效应的非参数估计

Instrumental variable methods are widely used to address unmeasured confounding, yet much of the existing literature has focused on the binary instrument setting. Extensions to continuous instruments often impose strong parametric assumptions for identification and estimation, which can be difficult to justify and may limit their applicability in complex real-world settings. In this work, we develop theory and methods for nonparametric estimation of treatment effects with a…

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Quasi-Bayes in Latent Variable Models

潜变量模型中的准贝叶斯方法

Latent variable models are widely used to account for unobserved determinants of economic behavior. This paper introduces a quasi-Bayes approach to nonparametrically estimate a large class of latent variable models. As an application, we model U.S. individual log earnings from the Panel Study of Income Dynamics (PSID) as the sum of latent permanent and transitory components. Simulations illustrate the favorable performance of quasi-Bayes estimators relative to common…

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LLM-based Agents for Automated Confounder Discovery and Subgroup Analysis in Causal Inference

用于因果推断中自动混杂发现与子群分析的大语言模型智能体

Estimating individualized treatment effects from observational data presents a persistent challenge due to unmeasured confounding and structural bias. Causal Machine Learning (causal ML) methods, such as causal trees and doubly robust estimators, provide tools for estimating conditional average treatment effects. These methods have limited effectiveness in complex real-world environments due to the presence of latent confounders or those described in unstructured formats.…

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A causal fused lasso for interpretable heterogeneous treatment effects estimation

用于可解释异质性处理效应估计的因果融合lasso

We propose a novel method for estimating heterogeneous treatment effects based on the fused lasso. By first ordering samples based on the propensity or prognostic score, we match units from the treatment and control groups. We then run the fused lasso to obtain piecewise constant treatment effects with respect to the ordering defined by the score. Similar to the existing methods based on discretizing the score, our methods yield interpretable subgroup effects. However,…

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Non-asymptotic estimates for accelerated high order Langevin Monte Carlo algorithms

加速高阶 Langevin Monte Carlo 算法的非渐近估计

In this paper, we propose two new algorithms, namely, aHOLA and aHOLLA, to sample from high-dimensional target distributions with possibly super-linearly growing potentials. We establish non-asymptotic convergence bounds for aHOLA in Wasserstein-1 and Wasserstein-2 distances with rates of convergence equal to $1+q/2$ and $1/2+q/4$, respectively, under a local Hölder condition with exponent $q\in(0,1]$ and a convexity at infinity condition on the potential of the target…

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