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Statistical Performance Guarantee for Subgroup Identification with Generic Machine Learning

通用机器学习子群识别的统计性能保证

Across a wide array of disciplines, many researchers use machine learning (ML) algorithms to identify a subgroup of individuals who are likely to benefit from a treatment the most (``exceptional responders'') or those who are harmed by it. A common approach to this subgroup identification problem consists of two steps. First, researchers estimate the conditional average treatment effect (CATE) using an ML algorithm. Next, they use the estimated CATE to select those…

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MOPED: A moving sum method for change point detection in pairwise extremal dependence

MOPED:检测成对极端依赖变点的移动和方法

It is increasingly the case with modern time series that many data sets of practical interest contain abrupt changes in structure. These changes may occur in complex characteristics such as the extremal dependence structure, and identifying such structural breaks remains a challenging problem. Many existing change point detection algorithms focus on changes in dependence across the entire distribution, rather than the tails, and approaches that are tailored to extremes…

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Semiparametric model averaging for high-dimensional quantile regression with nonignorable nonresponse

不可忽略缺失下高维分位数回归的半参数模型平均

Model averaging has demonstrated superior performance for ensemble forecasting in high-dimensional framework, its extension to incomplete datasets remains a critical but underexplored challenge. Moreover, identifying the parsimonious model through averaging procedure in quantile regression demands urgent methodological innovation. In this paper, we propose a novel model averaging method for high-dimensional quantile regression with nonignorable missingness. The idea is to…

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Root-n-consistent Conditional ML estimation of dynamic panel logit models with fixed effects

固定效应动态面板 Logit 模型的根号 n 一致条件极大似然估计

In this paper we first propose a root-n-consistent Conditional Maximum Likelihood (CML) estimator for all the common parameters in the panel logit AR(p) model with strictly exogenous covariates and fixed effects. Our CML estimator (CMLE) converges in probability faster and is more easily computed than the kernel-weighted CMLE of Honoré and Kyriazidou (2000). Next, we propose a root-n-consistent CMLE for the coefficients of the exogenous covariates only. We also discuss new…

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An adaptive design for optimizing treatment assignment in randomized clinical trials

优化随机临床试验处理分配的自适应设计

The treatment assignment mechanism in a randomized clinical trial can be optimized for statistical efficiency within a specified class of randomization mechanisms. Optimal designs of this type have been characterized in terms of the variances of potential outcomes conditional on baseline covariates. Approximating these optimal designs requires information about the conditional variance functions, which is often unavailable or unreliable at the design stage. As a practical…

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Signal Lasso with Non-Convex Penalties for Efficient Network Reconstruction and Topology Inference

非凸惩罚信号套索用于高效网络重构与拓扑推断

Inferring network structures remains an interesting question for its importance on the understanding and controlling collective dynamics of complex systems. The existing shrinking methods such as Lasso-type estimation can not suitably reveal such property. A new method recently suggested, called by {\it signal lasso} (or its updating version: adaptive signal lasso) was proposed to solve the network reconstruction problem, where the signal parameter can be shrunk to either 0…

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Multiply Robust Inference of Average Treatment Effects by High-dimensional Empirical Likelihood

利用高维经验似然进行平均处理效应的多重稳健推断

In this paper, we develop a multiply robust inference procedure of the average treatment effect (ATE) for data with high-dimensional covariates. We consider the case where it is difficult to correctly specify a single parametric model for the propensity scores (PS). For example, the target population is formed from heterogeneous sources with different treatment assignment mechanisms. We propose a novel high-dimensional empirical likelihood weighting method under soft…

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G-HIVE: Parameter Estimation and Approximate Inference for Multivariate Response Generalized Linear Models with Hidden Variables

G-HIVE:含隐藏变量的多响应广义线性模型参数估计与近似推断

In practice, there often exist unobserved variables, also termed hidden variables, associated with both the response and covariates. Existing works in the literature mostly focus on linear regression with hidden variables. However, when the regression model is non-linear, the presence of hidden variables leads to new challenges in parameter identification, estimation, and statistical inference. This paper studies multivariate response generalized linear models (GLMs) with…

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Considerations for Estimating Causal Effects of Informatively Timed Treatments

具有信息性处理时点的因果效应估计

Epidemiological studies are often concerned with estimating causal effects of a sequence of treatment decisions on survival outcomes. In many settings, treatment decisions do not occur at fixed, pre-specified followup times. Rather, timing varies across subjects in ways that may be informative of subsequent treatment decisions and potential outcomes. Awareness of the issue and its potential solutions is lacking in the literature, which motivate this work. Here, we formalize…

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Estimating Fiscal Multipliers by Combining Statistical Identification with Potentially Endogenous Proxies

结合统计识别与潜在内生代理变量估计财政乘数

Different proxy variables used in fiscal policy SVARs lead to contradicting conclusions regarding the size of fiscal multipliers. Our analysis suggests that the conflicting results may stem from violations of the proxy exogeneity assumptions. We propose a novel approach to include proxy variables into a Bayesian non-Gaussian SVAR, tailored to accommodate potentially endogenous proxies. Using our model, we find that increasing government spending is more effective in…

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Treatment effects at the margin: Everyone is marginal

边际上的处理效应:每个人都处于边际

This paper develops a framework for identifying treatment effects when a policy simultaneously alters both the incentive to participate and the outcome of interest -- such as hiring decisions and wages in response to employment subsidies; or working decisions and wages in response to job trainings. This framework was inspired by my PhD project on a Belgian reform that subsidised first-time hiring, inducing entry by marginal firms yet meanwhile changing the wages they pay.…

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Practically significant change points in high dimension -- measuring signal strength pro active component

高维时间序列中具有实际意义的变点:按活跃分量衡量信号强度

We consider the change point testing problem for high-dimensional time series. Unlike conventional approaches, where one tests whether the difference $δ$ of the mean vectors before and after the change point is equal to zero, we argue that the consideration of the null hypothesis $H_0:\|δ\|\leΔ$, for some norm $\|\cdot\|$ and a threshold $Δ>0$, is better suited. By the formulation of the null hypothesis as a composite hypothesis, the change point testing problem becomes…

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Discovering Heterogeneous Treatment Effects in Regression Discontinuity Designs

回归不连续设计中的异质性处理效应发现

The paper proposes a causal supervised machine learning algorithm to uncover treatment effect heterogeneity in sharp and fuzzy regression discontinuity (RD) designs. We develop a criterion for building an honest ``regression discontinuity tree'', where each leaf contains the RD estimate of a treatment conditional on the values of some pre-treatment covariates. It is a priori unknown which covariates are relevant for capturing treatment effect heterogeneity, and it is the…

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Change Point Detection on A Separable Model for Dynamic Networks

动态网络可分离模型的变点检测

This paper studies the unsupervised change point detection problem in time series of networks using the Separable Temporal Exponential-family Random Graph Model (STERGM). Inherently, dynamic network patterns are complex due to dyadic and temporal dependence, and change points detection can identify the discrepancies in the underlying data generating processes to facilitate downstream analysis. In particular, the STERGM that utilizes network statistics and nodal attributes to…

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Doubly robust estimation and sensitivity analysis with outcomes truncated by death in multi-arm clinical trials

多组临床试验中死亡截断结局的双重稳健估计与敏感性分析

In clinical trials, the observation of participant outcomes may frequently be hindered by death, leading to ambiguity in defining a scientifically meaningful final outcome for those who die. Principal stratification methods are valuable tools for addressing the average causal effect among always-survivors, i.e., the average treatment effect among a subpopulation defined as those who would survive regardless of treatment assignment. Although robust methods for the…

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Inference on Nonlinear Counterfactual Functionals under a Multiplicative IV Model

乘法工具变量模型下非线性反事实泛函的推断

Instrumental variable (IV) methods play a central role in causal inference, particularly in settings where treatment assignment is confounded by unobserved variables. IV methods have been extensively developed in recent years and applied across diverse domains, from economics to epidemiology. In this work, we study the recently introduced multiplicative IV (MIV) model and demonstrate its utility for causal inference beyond the average treatment effect. In particular, we show…

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Causal machine learning methods and use of cross-fitting in settings with high-dimensional confounding

高维混杂下的因果机器学习方法与交叉拟合

Observational epidemiological studies commonly seek to estimate the causal effect of an exposure on an outcome. Adjustment for potential confounding bias in modern studies is challenging due to the presence of high-dimensional confounding, which occurs when there are many confounders relative to sample size or complex relationships between continuous confounders and exposure and outcome. Doubly robust methods such as Augmented Inverse Probability Weighting (AIPW) and…

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HAL-Based Plug-in Estimation with Pointwise Asymptotic Normality of the Causal Dose-Response Curve

基于 HAL 的因果剂量反应曲线插件估计与逐点渐近正态性

Estimating and obtaining reliable inference for the marginally adjusted causal dose-response curve for continuous treatments without relying on parametric assumptions is a well-known statistical challenge. Parametric models risk introducing significant bias through model misspecification, compromising the accurate representation of the underlying data and dose-response relationship. On the other hand, nonparametric models face difficulties as the dose-response curve is not…

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Bounds in Wasserstein Distance for Locally Stationary Processes

局部平稳过程的 Wasserstein 距离界

Locally stationary (LSPs) constitute an essential modeling paradigm for capturing the nuanced dynamics inherent in time series data whose statistical characteristics, including mean and variance, evolve smoothly across time. In this paper, we introduce a novel conditional probability distribution estimator specifically tailored for LSPs, employing the Nadaraya-Watson (NW) kernel smoothing methodology. The NW estimator, a prominent local averaging technique, leverages kernel…

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Inference on Partially Identified Parameters with Separable Nuisance Parameters: a Two-Stage Method

可分离辅助参数下部分识别参数的两阶段推断

This paper develops a two-stage method for inference on partially identified parameters in moment inequality models with separable nuisance parameters. In the first stage, the nuisance parameters are estimated separately, and in the second stage, the identified set for the parameters of interest is constructed using a refined chi-squared test with variance correction that accounts for the first-stage estimation error. We establish the asymptotic validity of the proposed…

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A mixture logistic model for panel data with a Markov structure

具有马尔可夫结构的面板数据混合逻辑回归模型

In this study, we propose a mixture logistic regression model with a Markov structure, and consider the estimation of model parameters using maximum likelihood estimation. We also provide a forward type variable selection algorithm to choose the important explanatory variables to reduce the number of parameters in the proposed model.

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Inspection-Guided Randomization: A Flexible and Transparent Restricted Randomization Framework for Better Experimental Design

检查引导随机化:灵活透明的受限随机化实验设计框架

Randomized experiments are considered the gold standard for estimating causal effects. However, out of the set of possible randomized assignments, some may be likely to produce poor effect estimates and misleading conclusions. Restricted randomization is an experimental design strategy that filters out undesirable treatment assignments, but its application has primarily been limited to ensuring covariate balance in two-arm studies where the target estimand is the average…

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Network inference via approximate Bayesian computation. Illustration on a stochastic multi-population neural mass model

近似贝叶斯计算的网络推断:随机多群体神经质量模型示例

In this article, we propose an adapted sequential Monte Carlo approximate Bayesian computation (SMC-ABC) algorithm for network inference in coupled stochastic differential equations (SDEs) used for multivariate time series modeling. Our approach is motivated by neuroscience, specifically the challenge of estimating brain connectivity before and during epileptic seizures. To this end, we make four key contributions. First, we introduce a 6N-dimensional SDE to model the…

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Estimating the average treatment effect in cluster-randomized trials with misclassified outcomes and non-random validation subsets

结局误分类与非随机验证子集下整群随机试验的平均处理效应估计

Randomized trials are viewed as the benchmark for assessing causal effects of treatments on outcomes of interest. Nonetheless, challenges such as measurement error can undermine the standard causal assumptions for randomized trials. In ASPIRE, a cluster-randomized trial, pediatric primary care clinics were assigned to one of two treatments aimed at promoting clinician delivery of a secure firearm program to parents during well-child visits. A key outcome of interest is thus…

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