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Empirical Bayes for Data Integration

数据整合中的经验贝叶斯方法

We discuss the use of empirical Bayes for data integration, in the sense of transfer learning. Our main interest is in settings where one wishes to learn structure (e.g. feature selection) and one only has access to incomplete data from previous studies, such as summaries, estimates or lists of relevant features. We discuss differences between full Bayes and empirical Bayes, and develop a computational framework for the latter. We discuss how empirical Bayes attains…

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Variational Inference for Sparse Poisson Regression

稀疏泊松回归的变分推断

We have utilized the non-conjugate Variational Bayesian (VB) method for the problem of the sparse Poisson regression model. To provide approximate conjugacy in the model, the likelihood is approximated by a quadratic function, yielding conjugacy between the approximation component and the Gaussian prior on the regression coefficient. Three sparsity-enforcing priors (Laplace, Continuous Spike and Slab, and Bernoulli) are used for this problem. The proposed models are compared…

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Bridging Binarization: Causal Inference with Dichotomized Continuous Exposures

连接二值化与连续暴露:二分连续暴露的因果推断

The average treatment effect (ATE) is a common parameter estimated in causal inference literature, but it is only defined for binary exposures. Thus, despite concerns raised by some researchers, many studies seeking to estimate the causal effect of a continuous exposure create a new binary exposure variable by dichotomizing the continuous values into two categories. In this paper, we affirm binarization as a statistically valid method for answering causal questions about…

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Personalized Policy Learning through Discrete Experimentation: Theory and Empirical Evidence

通过离散实验学习个性化连续策略:理论与实证证据

Randomized Controlled Trials (RCTs), or A/B testing, have become the gold standard for optimizing various operational policies on online platforms. However, RCTs on these platforms typically cover a limited number of discrete treatment levels, while the platforms increasingly face complex operational challenges involving optimizing continuous variables, such as pricing and incentive programs. The current industry practice involves discretizing these continuous decision…

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Moving toward best practice when using propensity score weighting in survey observational studies

调查观察研究中倾向得分加权的规范实践

Propensity score weighting is a common method for estimating treatment effects with survey data. The method is applied to minimize confounding using measured covariates that are often different between individuals in treatment and control. However, existing literature does not reach a consensus on the optimal use of survey weights for population-level inference in the propensity score weighting analysis. Under the balancing weights framework, we provided a unified solution…

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Double Variable Importance Matching to Estimate Distinct Causal Effects on Event Probability and Timing

双重变量重要性匹配:区分事件概率与发生时间的因果效应

In many clinical contexts, estimating effects of treatment in time-to-event data is complicated not only by confounding, censoring, and heterogeneity, but also by the presence of a cured subpopulation in which the event of interest never occurs. In such settings, treatment may have distinct effects on (1) the probability of being cured and (2) the event timing among non-cured individuals. Standard survival analysis and causal inference methods typically do not separate cured…

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An Axiomatic Approach to Comparing Sensitivity Parameters

比较敏感性参数的公理化方法

Many methods are available for assessing the importance of omitted variables in linear regression. These methods typically make different, non-falsifiable assumptions. Hence the data alone cannot tell us which method is most appropriate. Since it is unreasonable to expect results to be robust against all possible robustness checks, researchers often use methods deemed ``interpretable,'' a subjective criterion with no formal definition. In contrast, we develop the first…

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Guardrailed Uplift Targeting: A Causal Optimization Playbook for Marketing Strategy

带业务约束的增量效应定向:营销策略的因果优化框架

This paper introduces a marketing decision framework that optimizes customer targeting by integrating heterogeneous treatment effect estimation with explicit business guardrails. The objective is to maximize revenue and retention while adhering to constraints such as budget, revenue protection, and customer experience. The framework first estimates Conditional Average Treatment Effects (CATE) using uplift learners, then solves a constrained allocation problem to decide whom…

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Covariate Selection for Joint Latent Space Modeling of Sparse Network Data

稀疏网络联合潜空间建模中的协变量选择

Network data are increasingly common in the social sciences and infectious disease epidemiology. Analyses often link network structure to node-level covariates, but existing methods falter with sparse networks and high-dimensional node features. We propose a joint latent space modeling framework for sparse networks with high-dimensional binary node covariates that performs covariate selection while accounting for uncertainty in estimated latent positions. Building on joint…

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Distributed Convoluted Rank Regression for Non-Shareable Data under Non-Additive Losses

非可加损失下不可共享数据的分布式卷积秩回归

We study high-dimensional rank regression when data are distributed across multiple machines and the loss is a non-additive U-statistic, as in convoluted rank regression (CRR). Classical communication-efficient surrogate likelihood (CSL) methods crucially rely on the additivity of the empirical loss and therefore break down for CRR, whose global loss couples all sample pairs across machines. We propose a distributed convoluted rank regression (DCRR) framework that constructs…

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Proper Correlation Coefficients for Nominal Random Variables

适用于名义尺度随机变量的相关系数

This paper develops an intuitive concept of perfect dependence between two variables of which at least one has a nominal scale. Perfect dependence is attainable for all marginal distributions. It furthermore proposes a set of dependence measures that are 1 if and only if this perfect dependence is satisfied. The advantages of these dependence measures relative to classical dependence measures like contingency coefficients, Goodman-Kruskal's lambda and tau and the so-called…

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Validating Causal Message Passing Against Network-Aware Methods on Real Experiments

在真实实验中将因果消息传递与网络感知方法比较验证

Estimating total treatment effects in the presence of network interference typically requires knowledge of the underlying interaction structure. However, in many practical settings, network data is either unavailable, incomplete, or measured with substantial error. We demonstrate that causal message passing, a methodology that leverages temporal structure in outcome data rather than network topology, can recover total treatment effects comparable to network-aware approaches.…

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Sparse group principal component analysis via double thresholding with application to multi-cellular programs

通过双重阈值实现稀疏组主成分分析:多细胞程序应用

Multi-cellular programs (MCPs) are coordinated patterns of gene expression across interacting cell types that collectively drive complex biological processes such as tissue development and immune responses. While MCPs are typically estimated from high-dimensional gene expression data using methods like sparse principal component analysis or latent factor models, these approaches often suffer from high computational costs and limited statistical power. In this work, we…

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Data-driven Error Estimation: Excess Risk Bounds without Class Complexity as Input

数据驱动的误差估计:无需输入函数类复杂度的超额风险界

Constructing confidence intervals that are simultaneously valid across a class of estimates is central to tasks such as multiple mean estimation, generalization guarantees, and adaptive experimental design. We frame this as an ``error estimation problem," where the goal is to determine a high-probability upper bound on the maximum error for a class of estimates. We propose an entirely data-driven approach that derives such bounds for both finite and infinite class settings,…

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Inference-Time Alignment for Diffusion Models via Variationally Stable Doob's Matching

基于变分稳定Doob匹配的扩散模型推理时对齐

Inference-time alignment for diffusion models aims to adapt a pre-trained reference diffusion model toward a target distribution without retraining the reference score network, thereby preserving the generative capacity of the reference model while enforcing desired properties at the inference time. A central mechanism for achieving such alignment is guidance, which modifies the sampling dynamics through an additional drift term. In this work, we introduce variationally…

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Diffusion Index Forecasting with Tensor Data

基于张量数据的扩散指数预测

In this paper, we consider diffusion index forecasting with both tensor and non-tensor predictors, where the tensor structure is preserved with a Canonical Polyadic (CP) tensor factor model. When the number of non-tensor predictors is small, we study the asymptotic properties of the least squares estimator in this tensor factor-augmented regression, allowing for factors with different strengths. We derive an analytical formula for prediction intervals that accounts for the…

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Mixture Quantiles Estimated by Constrained Linear Regression

用约束线性回归估计混合分位数

We study the problem of modeling univariate distributions via their quantile functions. We introduce a flexible family of distributions whose quantile function is a linear combination of basis quantiles. Because the model is linear in its parameters, estimation reduces to constrained linear regression, yielding a convex optimization problem that readily accommodates cardinality constraints as well as L1 or smoothness regularization. For Lq-type objectives we show the…

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Count Data Models with Heterogeneous Peer Effects under Rational Expectations

理性预期下具有异质同伴效应的计数数据模型

This paper develops a peer effect model for count responses under rational expectations. The model accounts for heterogeneity in peer effects across groups based on observed characteristics. Identification is based on the linear model condition that requires the presence of friends of friends who are not direct friends. I show that this identification condition extends to a broad class of nonlinear models. Parameters are estimated using a nested pseudo-likelihood approach.…

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Global Testing in Multivariate Regression Discontinuity Designs

多维断点回归设计中的全局检验

Regression discontinuity (RD) designs with multiple running variables arise in a growing number of empirical applications, including geographic boundaries and multi-score assignment rules. Although recent methodological work has extended estimation and inference tools to multivariate settings, far less attention has been devoted to developing global testing methods that formally assess whether a discontinuity exists anywhere along a multivariate treatment boundary. Existing…

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Conditional Extreme Value Estimation for Dependent Time Series

依赖时间序列的条件极值估计

We study the consistency and weak convergence of the conditional tail function and conditional Hill estimators under broad dependence assumptions for a heavy-tailed response sequence and a covariate sequence. Consistency is established under $α$-mixing, while asymptotic normality follows from $β$-mixing and second-order conditions. A key aspect of our approach is its versatile functional formulation in terms of the conditional tail process. Simulations demonstrate its…

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Functional-SVD for Heterogeneous Trajectories: Case Studies in Health

异质轨迹的函数奇异值分解:健康领域案例

Trajectory data, including time series and longitudinal measurements, are increasingly common in health-related domains such as biomedical research and epidemiology. Real-world trajectory data frequently exhibit heterogeneity across subjects such as patients, sites, and subpopulations, yet many traditional methods are not designed to accommodate such heterogeneity in data analysis. To address this, we propose a unified framework, termed Functional Singular Value…

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Bias-Reduced Estimation of Finite Mixtures: An Application to Latent Group Structures in Panel Data

有限混合模型的偏差缩减估计及面板潜在组结构应用

Finite mixture models are widely used in econometric analyses to capture unobserved heterogeneity. This paper shows that maximum likelihood estimation of finite mixtures of parametric densities can suffer from substantial finite-sample bias in all parameters under mild regularity conditions. The bias arises from the influence of outliers in component densities with unbounded or large support and increases with the degree of overlap among mixture components. I show that…

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Bayesian Estimation of Causal Effects Using Proxies of a Latent Interference Network

利用潜在干扰网络代理进行因果效应的贝叶斯估计

Network interference occurs when treatments assigned to some units affect the outcomes of others. Traditional approaches often assume that the observed network correctly specifies the interference structure. However, in practice, researchers frequently only have access to proxy measurements of the interference network due to limitations in data collection or potential mismatches between measured networks and actual interference pathways. In this paper, we introduce a…

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Conformal Prediction for Causal Effects of Continuous Treatments

连续治疗因果效应的共形预测

Uncertainty quantification of causal effects is crucial for safety-critical applications such as personalized medicine. A powerful approach for this is conformal prediction, which has several practical benefits due to model-agnostic finite-sample guarantees. Yet, existing methods for conformal prediction of causal effects are limited to binary/discrete treatments and make highly restrictive assumptions such as known propensity scores. In this work, we provide a novel…

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