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Empirical Bayes Estimation in Heterogeneous Coefficient Panel Models

异质系数面板模型中的经验贝叶斯估计

We develop an empirical Bayes (EB) G-modeling framework for short-panel linear models with nonparametric prior for the random intercepts, slopes, dynamics, and non-spherical error variances. We establish identification and consistency of the nonparametric maximum likelihood estimator (NPMLE) under general conditions, and provide low-level sufficient conditions for several models of empirical interest. Conditions for regret consistency of the EB estimators are also…

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A Doubly Robust Machine Learning Approach for Disentangling Treatment Effect Heterogeneity with Functional Outcomes

分解函数型结局处理效应异质性的双重稳健机器学习方法

Causal inference is paramount for understanding the effects of interventions, yet extracting personalized insights from increasingly complex data remains a significant challenge for modern machine learning. This is the case, in particular, when considering functional outcomes observed over a continuous domain (e.g., time, or space). Estimation of heterogeneous treatment effects, known as CATE, has emerged as a crucial tool for personalized decision-making, but existing…

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Renet: Principled and Efficient Relaxation for the Elastic Net via Dynamic Objective Selection

Renet:通过动态目标选择为弹性网提供有原则且高效的松弛方法

We introduce Renet, a principled generalization of the Relaxed Lasso to the Elastic Net family of estimators. While, on the one hand, $\ell_1$-regularization is a standard tool for variable selection in high-dimensional regimes and, on the other hand, the $\ell_2$ penalty provides stability and solution uniqueness through strict convexity, the standard Elastic Net nevertheless suffers from shrinkage bias that frequently yields suboptimal prediction accuracy. We propose to…

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Instrumented Difference-in-Differences with Heterogeneous Treatment Effects

异质处理效应下的工具变量双重差分

Many studies exploit variation in the timing of policy adoption across units as an instrument for treatment. This paper formalizes the underlying identification strategy as an instrumented difference-in-differences (DID-IV). In this design, a Wald-DID estimand, which scales the DID estimand of the outcome by the DID estimand of the treatment, captures the local average treatment effect on the treated (LATET). We extend the canonical DID-IV design to multiple period settings…

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Kernel-based Optimally Weighted Conformal Time-Series Prediction

基于核方法的最优加权保形时间序列预测

In this work, we present a novel conformal prediction method for time-series, which we call Kernel-based Optimally Weighted Conformal Prediction Intervals (KOWCPI). Specifically, KOWCPI adapts the classic Reweighted Nadaraya-Watson (RNW) estimator for quantile regression on dependent data and learns optimal data-adaptive weights. Theoretically, we tackle the challenge of establishing a conditional coverage guarantee for non-exchangeable data under strong mixing conditions on…

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Fact or friction: Jumps at ultra high frequency

事实还是摩擦:超高频价格跳跃

This paper shows that jumps in financial asset prices are often erroneously identified and are, in fact, rare events accounting for a very small proportion of the total price variation. We apply new econometric techniques to a comprehensive set of ultra high-frequency equity and foreign exchange tick data recorded at millisecond precision, allowing us to examine the price evolution at the individual order level. We show that in both theory and practice, traditional measures…

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Inference for High-Dimensional Local Projection

高维局部投影的统计推断

This paper rigorously analyzes the properties of the local projection (LP) methodology within a high-dimensional (HD) framework, with a central focus on achieving robust long-horizon inference. We integrate a general dependence structure into h-step ahead forecasting models via a flexible specification of the residual terms. Additionally, we study the corresponding HD covariance matrix estimation, explicitly addressing the complexity arising from the long-horizon setting.…

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Distributional Instruments: Identification and Estimation with Quantile Least Squares

分布型工具变量:识别与分位数最小二乘估计

We study instrumental-variable designs where policy reforms strongly shift the distribution of an endogenous variable but only weakly move its mean. We formalize this by introducing distributional relevance: instruments may be purely distributional. Within a triangular model, distributional relevance suffices for nonparametric identification of average structural effects via a control function. We then propose Quantile Least Squares (Q-LS), which aggregates conditional…

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Optimizing precision in stepped-wedge designs via machine learning and quadratic inference functions

通过机器学习与二次推断函数优化阶梯楔形设计的估计精度

Stepped-wedge designs are increasingly used in randomized experiments to accommodate logistical and ethical constraints by staggering treatment roll-out over time. Despite their popularity, existing analytical methods largely rely on parametric models with linear covariate adjustment and prespecified correlation structures, which may limit achievable precision in practice. We propose a new class of estimators for the causal average treatment effect in stepped-wedge designs…

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Generalized Prediction-Powered Inference, with Application to Binary Classifier Evaluation

广义预测驱动推断及其在二分类器评估中的应用

In the partially-observed outcome setting, a recent set of proposals known as "prediction-powered inference" (PPI) involve (i) applying a pre-trained machine learning model to predict the response, and then (ii) using these predictions to obtain an estimator of the parameter of interest with asymptotic variance no greater than that which would be obtained using only the labeled observations. While existing PPI proposals consider estimators arising from M-estimation, in this…

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A roadmap for systematic identification and analysis of multiple biases in causal inference

因果推断中系统识别与联合分析多重偏差的路线图

Observational studies examining causal effects rely on unverifiable assumptions, the violation of which can induce multiple biases. Quantitative bias analysis (QBA) methods examine the sensitivity of findings to such violations, generally, by producing estimates under alternative assumptions, incorporating external information. Although substantial guidance exists for implementing QBA, there is limited guidance on how to systematically determine the assumptions underlying a…

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Modewise Additive Factor Model for Matrix Time Series

矩阵时间序列的逐模态加性因子模型

We introduce a Modewise Additive Factor Model (MAFM) for matrix-valued time series that captures row-specific and column-specific latent effects through an additive structure, offering greater flexibility than multiplicative frameworks such as Tucker and CP factor models. In MAFM, each observation decomposes into a row-factor component, a column-factor component, and noise, allowing distinct sources of variation along different modes to be modeled separately. We develop a…

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Doubly Robust Estimation of Desirability of Outcome Ranking (DOOR) Probability with Application to MDRO Studies

结局优劣排序概率的双重稳健估计及其耐多药菌研究应用

In observational studies, adjusting for confounders is required if a treatment comparison is planned. A crude comparison of the primary endpoint without covariate adjustment will suffer from biases, and the addition of regression models could improve precision by incorporating imbalanced covariates and thus help make correct inference. Desirability of outcome ranking (DOOR) is a patient-centric benefit-risk evaluation methodology designed for randomized clinical trials.…

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Dimension-free Bounds for Covariance Estimation with Tensor-Train Structure

张量列结构下协方差估计的无维界

We consider a problem of covariance estimation from a sample of i.i.d. high-dimensional random vectors. To avoid the curse of dimensionality, we impose an additional assumption on the structure of the covariance matrix $Σ$. To be more precise, we study the case when $Σ$ can be approximated by a sum of double Kronecker products of smaller matrices in a tensor train (TT) format. Our setup naturally extends widely known Kronecker sum and CANDECOMP/PARAFAC models but admits…

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Nonparametric Testability of Slutsky Symmetry

斯勒茨基对称性的非参数可检验性

Economic theory implies strong limitations on what types of consumption behavior are considered rational. Rationality implies that the Slutsky matrix, which captures the substitution effects of compensated price changes on demand for different goods, is symmetric and negative semi-definite. While empirically informed versions of negative semi-definiteness have been shown to be nonparametrically testable, the analogous question for Slutsky symmetry has remained open.…

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Bayesian identification of early warning signals for long-range dependent climatic time series

长程相依气候时间序列早期预警信号的贝叶斯识别

Detecting early warning signals in climatic time series is essential for anticipating critical transitions and tipping points. Common statistical indicators include increased variance and lag-one autocorrelation prior to bifurcation points. However, these indicators are sensitive to observational noise, long-term mean trends, and long-memory dependence, all of which are prevalent in climatic time series. Such effects can easily obscure genuine signals or generate spurious…

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Variational autoencoder for inference of nonlinear mixed effect models based on ordinary differential equations

基于常微分方程的非线性混合效应模型的变分自编码器推断

We propose a variational autoencoder (VAE) approach for parameter estimation in nonlinear mixed-effects models based on ordinary differential equations (NLME-ODEs) using longitudinal data from multiple subjects. In moderate dimensions, likelihood-based inference via the stochastic approximation EM algorithm (SAEM) is widely used, but it relies on Markov Chain Monte-Carlo (MCMC) to approximate subject-specific posteriors. As model complexity increases or observations per…

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Estimating Interventional Distributions with Uncertain Causal Graphs through Meta-Learning

通过元学习估计因果图不确定时的干预分布

In scientific domains -- from biology to the social sciences -- many questions boil down to \textit{What effect will we observe if we intervene on a particular variable?} If the causal relationships (e.g.~a causal graph) are known, it is possible to estimate the intervention distributions. In the absence of this domain knowledge, the causal structure must be discovered from the available observational data. However, observational data are often compatible with multiple…

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A joint QoL-Survival framework with debiased estimation under truncation by death

死亡截断下生活质量与生存的联合框架及去偏估计

Evaluating quality-of-life (QoL) outcomes in populations with high mortality risk is complicated by truncation by death, since QoL is undefined for individuals who do not survive to the planned measurement time. We propose a framework that jointly models the distribution of QoL and survival without extrapolating QoL beyond death. Inspired by multistate formulations, we extend the joint characterization of binary health states and mortality to continuous QoL outcomes. Because…

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Asymptotic Inference for Rank Correlations

秩相关系数的渐近推断

Kendall's tau and Spearman's rho are widely used tools for measuring dependence. Surprisingly, when it comes to asymptotic inference for these rank correlations, some fundamental results and methods have not yet been developed, in particular for discrete random variables and in the time series case, and concerning variance estimation in general. Consequently, asymptotic confidence intervals are not available. We provide a comprehensive treatment of asymptotic inference for…

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Holistic Multi-Scale Inference of the Leverage Effect: Efficiency under Dependent Microstructure Noise

杠杆效应的整体多尺度推断:相依微观结构噪声下的效率

This paper addresses the long-standing challenge of estimating the leverage effect from high-frequency data contaminated by dependent, non-Gaussian microstructure noise. We depart from the conventional reliance on pre-averaging or volatility "plug-in" methods by introducing a holistic multi-scale framework that operates directly on the leverage effect. We propose two novel estimators: the Subsampling-and-Averaging Leverage Effect (SALE) and the Multi-Scale Leverage Effect…

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Mapping Drivers of Greenness: Spatial Variable Selection for MODIS Vegetation Indices

植被绿度驱动因素的空间变量选择:面向 MODIS 植被指数

Understanding how environmental drivers relate to vegetation condition motivates spatially varying regression models, but estimating a separate coefficient surface for every predictor can yield noisy patterns and poor interpretability when many predictors are irrelevant. Motivated by MODIS vegetation index studies, we examine predictors from spectral bands, productivity and energy fluxes, observation geometry, and land surface characteristics. Because these relationships…

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Triply Robust Panel Estimators

三重稳健面板估计量

This paper studies estimation of causal effects in a panel data setting. We introduce a new estimator, the Triply RObust Panel (TROP) estimator, that combines (i) a flexible model for the potential outcomes based on a low-rank factor structure on top of a two-way-fixed effect specification, with (ii) unit weights intended to upweight units similar to the treated units and (iii) time weights intended to upweight time periods close to the treated time periods. We study the…

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Estimating causal effects of functional treatments with modified functional treatment policies

通过修正函数型处理策略估计函数型处理的因果效应

Functional data are increasingly prevalent in biomedical research. While functional data analysis has been established for decades, causal inference with functional treatments remains largely unexplored. Existing methods typically focus on estimating the causal average dose response functional (ADRF), which requires strong positivity assumptions and offers limited interpretability. In this work, we target a new causal estimand, the modified functional treatment policy…

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