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Characterizing Survivor Principal Strata Over Time: Identification, Efficient Estimation, and Sensitivity Analysis

随时间刻画幸存者主层:识别、有效估计与敏感性分析

Longitudinal studies with functional outcomes subject to truncation-by-death frequently report time-indexed survivor average causal effect estimates, defined among individuals who would survive regardless of treatment assignment. Because the survivor stratum can change over time, the resulting effect estimates may pertain to populations with different characteristics. We propose accompanying survivor average causal effect estimates with measures of covariate divergence…

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On the use of G-computation in small randomized controlled trials with many covariates

小样本多协变量随机对照试验中的G计算

In contemporary randomized controlled trials (RCTs), the number of patients is often small relative to the number of baseline covariates collected. In such settings, maximum likelihood estimators of conditional treatment effects in generalized linear models, along with their standard errors, may exhibit substantial bias. This study examines whether similar bias arises in G-computation estimators of marginal treatment effects, which are known for their robustness to model…

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Debiased Inference for Bounding Wage Inequality with Many Controls

多控制变量下工资不平等界的去偏推断

We study estimation and inference for a partially identified parameter whose identified set depends on a first-stage nuisance parameter that must itself be estimated. Combining the criterion-function approach with the theory of Neyman-orthogonal moments that underlies double/debiased machine learning, we propose a two-step procedure: the point-identified nuisance is estimated by flexible machine-learning methods, and the set-identified target is recovered as a level set of a…

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Debiased Machine Learning for Unobserved Heterogeneity: High-Dimensional Panels and Measurement Error Models

不可观测异质性的去偏机器学习:高维面板与测量误差模型

Developing robust inference for models with nonparametric Unobserved Heterogeneity (UH) is both important and challenging. We propose novel Debiased Machine Learning (DML) procedures for valid inference on functionals of UH, allowing for partial identification of multivariate target and high-dimensional nuisance parameters. Our main contribution is a full characterization of all relevant Neyman-orthogonal moments in models with nonparametric UH, where relevance means…

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Debiased and Simultaneous Inference for Heterogeneous Factorial Effect Modifiers via Residualized Walsh-Hadamard Scores

基于残差化 Walsh–Hadamard 得分的异质析因效应修饰因子去偏与同时推断

In factorial randomized experiments with $K$ binary treatment components, we study which baseline covariates modify component main effects and interactions. We define effect-modifier cells $(j,S)$, $j\in[p]$ and $\emptyset\neq S\subseteq[K]$, through the coefficients $θ^\ast_{jS}$ of population linear projections of conditional Walsh--Hadamard contrasts $τ_{S}$ onto standardized covariates. Using baseline-robust direct scores, we develop frequentist inference for all $p(2^K-1)$…

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The INSIDE assumption under all positive coding: interpretation and partial empirical assessment

全正编码下的 INSIDE 假设:解释与部分经验评估

Mendelian randomisation (MR) implemented through instrumental variable (IV) analysis is a popular strategy for strengthening causal inference in observational studies. A key assumption for several MR estimators, including MR-Egger regression, is the INstrument Strength Independent of Direct Effect (INSIDE) assumption. However, there is no established empirical test for assessing the plausibility of this assumption. Moreover, INSIDE depends on how genetic variants are coded…

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Are there asymmetries in euro area monetary policy transmission?

欧元区货币政策传导是否存在不对称性?

We answer the question posed in the title with a nonlinear mixed-frequency vector autoregression, estimated with Bayesian additive regression trees. The model combines monthly macro-financial variables with quarterly bank lending survey data, and identifies the dynamic responses from high-frequency policy surprises. Sign asymmetry dominates; a tightening produces monetary policy transmission mostly in line with the theoretical predictions, whereas easing of any size produces…

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A statistical framework for identifying subgroup vulnerability to predictive multiplicity in clinical AI

识别临床AI预测多重性中亚组脆弱性的统计框架

AI models trained on the same data can disagree about patient risk, with disagreement potentially concentrated in clinically important subgroups. We propose V(S), a statistically grounded vulnerability index combining an observable lower-bound witness of model disagreement with clinical severity, and develop inference and multiplicity-adjustment procedures for auditing prespecified subgroups. We applied the framework to two large critical-care cohorts, MIMIC-IV (n = 65,078)…

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Who Drives the System? Classifying Mean-Field Particle Systems from Trajectory Data

谁驱动系统?根据轨迹数据分类平均场粒子系统

We study the supervised classification problem for interacting particle systems (IPS) from trajectory observations. The IPS belongs to one of K classes, each characterized by a distinct interaction drift. Given a learning dataset, the goal is then to predict the class label of a newly observed system based on the trajectory of a single particle. This setting raises several statistical challenges. First, the particles within each system interact and are therefore dependent.…

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BRP-GABLE: An Interpretable Rule-Based Prediction Framework for Multiple Outcome Types

BRP-GABLE:适用于多种结果类型的可解释规则预测框架

Interpretable prediction models are important in biomedical research, where predictive accuracy must often be balanced against the ability to examine predictor-outcome relationships. Automatic Binary Logistic Estimation (ABLE) provides interpretable rule-based representations by constructing additive models using threshold rules. However, the original method is restricted to binary outcomes, and its greedy forward construction follows a search path, making candidate rules…

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Testing for Unobserved Heterogeneity in Censored Duration Models: EM Approach

删失持续时间模型中的未观测异质性检验:EM方法

Ignoring unobserved heterogeneity in duration models biases parameter estimates and invalidates inference, but testing for it is non-regular: the null hypothesis lies on the boundary of the parameter space and some parameters are unidentified under the null. These features render standard asymptotic theory inapplicable. This paper develops an EM test for unobserved heterogeneity in censored Weibull duration models, building on the EM approach of Li, Chen, and Marriott…

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Optimal detection of general moment changes: Simultaneous mean and covariance change detection and beyond

一般矩变点的最优检测:均值与协方差变点同时检测及推广

We study multiple change-point detection in multivariate time series whose distributions change in a piecewise constant manner. Distributional changes can manifest across different moment orders, from shifts in the mean and covariance to changes in higher-order moments. Higher-order moments capture increasingly rich distributional features but become difficult to estimate in high dimensions. Our tensor representation unifies moments of different orders within a common linear…

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Big Wins, Small Net Gains: Direct and Spillover Effects of First Industry Entries in Puerto Rico

本地收益大、净收益小:波多黎各首次行业进入的直接与溢出效应

I study how first sizable industry entries reshape local and neighboring labor markets in Puerto Rico. Using over a decade of quarterly municipality--industry data (2014Q1--2025Q1), I identify ``first sizable entries'' as large, persistent jumps in establishments, covered employment, and wage bill, and treat these as shocks to local industry presence at the municipio--industry level. Methodologically, I combine staggered-adoption difference-in-differences estimators that are…

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A Dimension-Agnostic Bootstrap Anderson-Rubin Test For Instrumental Variable Regressions

工具变量回归中维度自适应的自助法 Anderson–Rubin 检验

Weak-identification-robust tests for instrumental variable (IV) regressions are typically developed separately depending on whether the number of IVs is treated as fixed or increasing with the sample size, forcing researchers to make a stance on the asymptotic behavior, which is often ambiguous in practice. This paper proposes a bootstrap-based, dimension-agnostic Anderson-Rubin (AR) test that achieves correct asymptotic size regardless of whether the number of IVs is fixed…

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Continuously Updating GMM in Linear IV Models: A Polynomial Approach

线性IV模型中持续更新GMM的多项式方法

This paper characterizes the global minimum of the continuously updating generalized method of moments (CU-GMM) objective in linear instrumental variables models. We allow optimal weighting matrices under heteroskedasticity, autocorrelation, or clustering. We show that the objective is a ratio of polynomials. For one endogenous regressor, stationary points of CU-GMM objective function are real eigenvalues of a companion matrix. Comparing their objective values with the value…

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LOCO-AdaMP: Built-in LOCO Inference for Adaptive Minipatch Ensembles with Enhanced Prediction

LOCO-AdaMP:兼顾预测与内置变量重要性推断的自适应小块集成

As black-box machine learning models become increasingly common, extracting interpretations with uncertainty quantification has become a critical challenge. One popular type of interpretation is leave-one-covariate-out (LOCO) feature importance, while prior LOCO inference methods often require data-splitting or model-refitting. A recent ensemble framework, LOCO-MP, addresses these challenges using minipatches that subsample both observations and features, but massive feature…

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Is the treatment beneficial? Causal Inference with Ordinal Outcomes: A Bayesian Solution

处理是否有益?有序结局因果推断的贝叶斯方法

Randomized experiments with ordinal outcomes are common across scientific applications, but conventional causal estimands such as the average treatment effect are difficult to interpret because ordinal categories lack meaningful numerical spacing. Two interpretable estimands, the probabilities that the treatment is beneficial and strictly beneficial, depend on the joint distribution of the potential outcomes and are therefore not identifiable from observed data. The sharp…

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Cross-Fitting-Free Debiased Machine Learning with Multiway Dependence

多维聚类依赖下无需交叉拟合的去偏机器学习

This paper develops an asymptotic theory for two-step debiased machine learning (DML) estimators in generalised method of moments (GMM) models with general multiway clustered dependence, without relying on cross-fitting. While cross-fitting is commonly employed, it can be statistically inefficient and computationally burdensome when first-stage learners are complex and the effective sample size is governed by the number of independent clusters. We show that valid inference…

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Graph-Split Bayesian Causal Forest for Spatial Heterogeneous Treatment Effect Estimation

图分割贝叶斯因果森林:空间异质性处理效应估计

In spatial observational studies, treatment assignment and outcomes often exhibit spatial dependence patterns, and treatment effects may vary across space and subpopulations due to both measured and unmeasured spatially structured confounders. Accounting for spatial dependence while estimating heterogeneous treatment effects (HTEs) is a central task in spatial causal inference. Causal Bayesian additive regression tree methods are popular nonparametric methods for modeling…

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Nonparametric Identification and Estimation of Causal Effects on Latent Outcomes

潜在结果变量因果效应的非参数识别与估计

How should researchers conduct causal inference when the outcome of interest is latent and measured imperfectly by multiple indicators? We develop a general nonparametric framework for identifying and estimating average treatment effects on latent outcomes in randomized experiments. We show that latent-outcome estimation faces a fundamental but overlooked noncomparability problem due to measurement-set dependence: adding, removing, or replacing measurement targets a…

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Simple Specification-Free Causal Inference in Large Panels

大面板中的简洁、无需特定参数设定的因果推断

We propose a simple and transparent approach to causal inference using panel data with a large number of units and periods. Instead of imposing a particular parametric specification on the untreated potential outcomes, we assume they follow a nonparametric nonseparable factor model. We use long pre-treatment outcome histories to construct a measure of similarity between the latent factors of different units. Using this measure, we impute missing counterfactual means and…

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BGM-IV: AI-Powered Bayesian Generative Modeling for Instrumental Variable Regression with High-Dimensional Covariates

BGM-IV:面向高维协变量工具变量回归的贝叶斯生成建模

Instrumental-variable (IV) regression enables causal estimation under endogeneity, but modern IV problems often involve nonlinear structural effects and high-dimensional covariates. Existing methods typically operate in observed or generic learned feature spaces, and they often yield point estimates without uncertainty quantification. We introduce BGM-IV, a Bayesian generative modeling approach that performs nonlinear IV regression through posterior inference in a causally…

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Data-Driven Tuning in Kernel Specification Tests: Selection Asymptotics, Validity, and Power

核设定检验的数据驱动调参:选择渐近理论、有效性与功效

We develop model checks for conditional moment restrictions whose tuning parameters, the kernel bandwidth and the regularization level, are selected by cross-validation. The tests regress the estimated residuals on the covariates via kernel ridge regression (KRR), yielding a coefficient function in a reproducing kernel Hilbert space (RKHS) that vanishes under the null and is nonzero for any misspecification not annihilated by the Neyman projection. Our central contribution…

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Identification and Estimation in a Nonseparable Instrumental Variable Model with Multivariate Outcomes

多元结果非可分工具变量模型的识别与估计

This paper proposes a novel nonseparable instrumental variable model to address endogeneity in settings with multivariate outcomes. While traditional approaches typically estimate separate one-dimensional quantile models for each outcome, the inherent correlation among different dimensions frequently invalidates their fundamental assumptions. To overcome this limitation, our framework jointly models the distribution of multiple outcomes. By assuming that the structural…

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