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底层有向混合图上的簇图：聚合层面因果效应识别AI 解读

The do-calculus is a sound and complete tool for identifying causal effects in acyclic directed mixed graphs (ADMGs) induced by structural causal models (SCMs). However, in many real-world applications, especially in high-dimensional setting, constructing a fully specified ADMG is often infeasible. This limitation has led to growing interest in partially specified causal representations, particularly through cluster-directed mixed graphs (C-DMGs), which group variables into…

利用专家混合模型估计依从者平均因果效应AI 解读

Treatment non-compliance, where individuals deviate from their assigned experimental conditions, frequently complicates the estimation of causal effects. To address this, we introduce a novel learning framework based on a mixture of experts architecture to estimate the Complier Average Causal Effect (CACE). Our framework provides a flexible alternative to classical instrumental variable methods by relaxing their strict monotonicity and exclusion restriction assumptions. We…

为后续工具变量回归学习处理变量表征AI 解读

Traditional instrumental variable (IV) estimators face a fundamental constraint: they can only accommodate as many endogenous treatment variables as available instruments. This limitation becomes particularly challenging in settings where the treatment is presented in a high-dimensional and unstructured manner (e.g. descriptions of patient treatment pathways in a hospital). In such settings, researchers typically resort to applying unsupervised dimension reduction techniques…

干扰程度：存在干扰时因果推断的一般框架AI 解读

One core assumption typically adopted for valid causal inference is that of no interference between experimental units, i.e., the outcome of an experimental unit is unaffected by the treatments assigned to other experimental units. This assumption can be violated in real-life experiments, which significantly complicates the task of causal inference. As the number of potential outcomes increases, it becomes challenging to disentangle direct treatment effects from…

条件矩限制的双重机器学习：工具变量回归、近端因果学习及拓展AI 解读

Solving conditional moment restrictions (CMRs) is a key problem considered in statistics, causal inference, and econometrics, where the aim is to solve for a function of interest that satisfies some conditional moment equalities. Specifically, many techniques for causal inference, such as instrumental variable (IV) regression and proximal causal learning (PCL), are CMR problems. Most CMR estimators use a two-stage approach, where the first-stage estimation is directly…

泊松有向图模型的似然比检验AI 解读

Directed acyclic graphs are widely used to describe the causal effects among random variables, and the inference of those causal effects has become an popular topic in statistics and machine learning, and has wide applications in neuroinformatics, bioinformatics and so on. However, most studies focus on the estimation or inference of the directional relations among continuous random variables, those among discrete random variables have not gained much attentions. In this…

利用特异性进行观察研究中的因果推断AI 解读

Hill's specificity criterion has been highly influential in biomedical and epidemiological research. However, it remains controversial and its application often relies on subjective and qualitative analysis without a comprehensive and rigorous causal theory. Focusing on unmeasured confounding adjustment with multiple treatments and multiple outcomes, this paper develops a formal and quantitative framework for leveraging specificity for causal inference in observational…

利用外部对照提高随机试验累积发生率估计的精度AI 解读

Augmenting the control arm in clinical trials with external data can improve statistical power for demonstrating treatment effects. In many time-to-event outcome trials, participants are subject to truncation by death. Direct application of methods for competing risks analysis on the joint data may introduce bias, for example, due to covariate shifts between the populations. In this work, we consider transportability of the conditional cause-specific hazard of the event of…

秘鲁矿业米塔制度的持久影响：双重机器学习方法AI 解读

This study examines the long-term economic impact of the colonial Mita system in Peru, building on Melissa Dell's foundational work on the enduring effects of forced labor institutions. The Mita, imposed by the Spanish colonial authorities from 1573 to 1812, required indigenous communities within a designated boundary to supply labor to mines, primarily near Potosi. Dell's original regression discontinuity design (RDD) analysis, leveraging the Mita boundary to estimate the…

恰好识别模型中弱工具变量稳健推断程序的实证比较AI 解读

Instrumental variable (IV) regression is recognized as one of the five core methods for causal inference, as identified by Angrist and Pischke (2008). This paper compares two leading approaches to inference under weak identification for just-identified IV models: the classical Anderson-Rubin (AR) procedure and the recently popular tF method proposed by Lee et al. (2022). Using replication data from the American Economic Review (AER) and Monte Carlo simulation experiments, we…

局部因果发现中的结构限制：识别目标变量的直接原因AI 解读

We consider the problem of learning a set of direct causes of a target variable from an observational joint distribution. Learning directed acyclic graphs (DAGs) that represent the causal structure is a fundamental problem in science. Several results are known when the full DAG is identifiable from the distribution, such as assuming a nonlinear Gaussian data-generating process. Here, we are only interested in identifying the direct causes of one target variable (local causal…

高效的双重差分与事件研究估计量AI 解读

This paper investigates efficient Difference-in-Differences (DiD) and Event Study (ES) estimation using short panel data sets within the heterogeneous treatment effect framework, free from parametric functional form assumptions and allowing for variation in treatment timing. We provide an equivalent characterization of the DiD potential outcome model using sequential conditional moment restrictions on observables, which shows that the DiD identification assumptions typically…

部分识别下处理选择问题的决策理论AI 解读

We apply classical statistical decision theory to a large class of treatment choice problems with partial identification. We show that, in a general class of problems with Gaussian likelihood, all decision rules are admissible; it is maximin-welfare optimal to ignore all data; and, for severe enough partial identification, there are infinitely many minimax-regret optimal decision rules, all of which sometimes randomize the policy recommendation. We uniquely characterize the…

高适应Lasso隐含工作模型中的正则化目标最大似然估计AI 解读

We address the challenge of performing Targeted Maximum Likelihood Estimation (TMLE) after an initial Highly Adaptive Lasso (HAL) fit. Existing approaches that utilize the data-adaptive working model selected by HAL-such as the relaxed HAL update-can be simple and versatile but may become computationally unstable when the HAL basis expansions introduce collinearity. Undersmoothed HAL may fail to solve the efficient influence curve (EIC) at the desired level without…

何时可以使用双向固定效应：与新型动态双重差分估计量的比较AI 解读

The conventional Two-Way Fixed-Effects (TWFE) estimator has come under scrutiny lately. Recent literature has revealed potential shortcomings of TWFE when the treatment effects are heterogeneous. Scholars have developed new advanced dynamic Difference-in-Differences (DiD) estimators to tackle these potential shortcomings. However, confusion remains in applied research as to when the conventional TWFE is biased and what issues the novel estimators can and cannot address. In…

FedECA：分布式生存数据因果推断的联邦外部对照组AI 解读

External control arms can inform early clinical development of experimental drugs and provide efficacy evidence for regulatory approval. However, accessing sufficient real-world or historical clinical trials data is challenging. Indeed, regulations protecting patients' rights by strictly controlling data processing make pooling data from multiple sources in a central server often difficult. To address these limitations, we develop a method that leverages federated learning…

用于政策学习的自适应实验设计AI 解读

This study investigates the contextual best arm identification (BAI) problem, aiming to design an adaptive experiment to identify the best treatment arm conditioned on contextual information (covariates). We consider a decision-maker who assigns treatment arms to experimental units during an experiment and recommends the estimated best treatment arm based on the contexts at the end of the experiment. The decision-maker uses a policy for recommendations, which is a function…

序贯合成双重差分AI 解读

We propose the Sequential Synthetic Difference-in-Differences (Sequential SDiD) estimator for event studies with staggered treatment adoption, particularly when the parallel trends assumption fails. The method uses an iterative imputation procedure on aggregated data, where estimates for early-adopting cohorts are used to construct counterfactuals for later ones. We prove the estimator is asymptotically equivalent to an infeasible oracle OLS estimator within a linear model…

异质性处理效应的统计学习：预训练、预后与预测AI 解读

Robust estimation of heterogeneous treatment effects is a fundamental challenge for optimal decision-making in domains ranging from personalized medicine to educational policy. In recent years, predictive machine learning has emerged as a valuable toolbox for causal estimation, enabling more flexible effect estimation. However, accurately estimating conditional average treatment effects (CATE) remains a major challenge, particularly in the presence of many covariates. In…

独立增量与组序贯检验AI 解读

Widely used methods and software for group sequential tests of a null hypothesis of no treatment difference that allow for early stopping of a clinical trial depend primarily on the fact that sequentially-computed test statistics have the independent increments property. However, there are many practical situations where the sequentially-computed test statistics do not possess this property. Key examples are in trials where the primary outcome is a time to an event but where…

超越马尔可夫等价类的稳健因果效应识别AI 解读

Causal effect identification typically requires a fully specified causal graph, which can be difficult to obtain in practice. We provide a sufficient criterion for identifying causal effects from a candidate set of Markov equivalence classes with added background knowledge, which represents cases where determining the causal graph up to a single Markov equivalence class is challenging. Such cases can happen, for example, when the untestable assumptions (e.g. faithfulness)…

KANITE：用于个体处理效应估计的 Kolmogorov–Arnold 网络AI 解读

We introduce KANITE, a framework leveraging Kolmogorov-Arnold Networks (KANs) for Individual Treatment Effect (ITE) estimation under multiple treatments setting in causal inference. By utilizing KAN's unique abilities to learn univariate activation functions as opposed to learning linear weights by Multi-Layer Perceptrons (MLPs), we improve the estimates of ITEs. The KANITE framework comprises two key architectures: 1.Integral Probability Metric (IPM) architecture: This…

二元结果随机实验精确置信区间的快速计算AI 解读

Given a randomized experiment with binary outcomes, exact confidence intervals for the average causal effect of the treatment can be computed through a series of permutation tests. This approach requires minimal assumptions and is valid for all sample sizes, as it does not rely on large-sample approximations such as those implied by the central limit theorem. We show that these confidence intervals can be found in $O(n \log n)$ permutation tests in the case of balanced…

缺失特定独立性与机制变化下的因果推断AI 解读

The recovery of causal effects in structural models with missing data often relies on $m$-graphs, which assume that missingness mechanisms do not directly influence substantive variables. Yet, in many real-world settings, missing data can alter decision-making processes, as the absence of key information may affect downstream actions and states. To overcome this limitation, we introduce $lm$-SCMs and $lm$-graphs, which extend $m$-graphs by integrating a label set that…